Page last updated: 2024-08-24

sparfloxacin and Torsade de Pointes

sparfloxacin has been researched along with Torsade de Pointes in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (10.00)	18.2507
2000's	6 (60.00)	29.6817
2010's	3 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Kang, W; Kim, EJ; Lee, HW; Lim, MS; Noh, K; Park, J; Seo, JJ; Seong, SJ; Yoon, YR	1
Bae, YM; Cho, H; Kim, B; Kim, HJ; Kim, JG; Kim, KS; Leem, CH; Park, SW; Shin, HC; Sung, DJ; Won, KJ; Zhang, YH	1
Byotra, SP; Kakar, A	1
Sugiyama, A	1
Ahluwalia, G	1
Chiba, K; Hashimoto, K; Sugiyama, A; Takasuna, K	1
Gallacher, DJ; Lu, HR; Van de Water, A; Vlaminckx, E	1
Dupont, H; Gachot, B; Regnier, B; Souweine, B; Timsit, JF; Wolff, M	1
Chiba, K; Hashimoto, K; Satoh, Y; Shiina, H; Sugiyama, A	1

Reviews

1 review(s) available for sparfloxacin and Torsade de Pointes

Article	Year
[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 121, Issue:6 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Antitubercular Agents; Cation Transport Proteins; Cisapride; Disease Models, Animal; Dogs; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gastrointestinal Agents; Haloperidol; Histamine H1 Antagonists; Long QT Syndrome; Potassium Channels; Potassium Channels, Voltage-Gated; Sulpiride; Terfenadine; Torsades de Pointes	2003

Article

Year

[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 121, Issue:6

Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Antitubercular Agents; Cation Transport Proteins; Cisapride; Disease Models, Animal; Dogs; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gastrointestinal Agents; Haloperidol; Histamine H1 Antagonists; Long QT Syndrome; Potassium Channels; Potassium Channels, Voltage-Gated; Sulpiride; Terfenadine; Torsades de Pointes

2003

Other Studies

9 other study(ies) available for sparfloxacin and Torsade de Pointes

Article	Year
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Pharmacometabolomic approach to predict QT prolongation in guinea pigs. PloS one, 2013, Volume: 8, Issue:4 Topics: Animals; Electrocardiography; Fluoroquinolones; Guinea Pigs; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Phenotype; Prognosis; Sotalol; Torsades de Pointes	2013
Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs. PloS one, 2016, Volume: 11, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Heart Ventricles; Mice; Myocardial Contraction; Myocytes, Cardiac; Potassium Channel Blockers; Rats, Sprague-Dawley; Torsades de Pointes	2016
Torsade de pointes probably induced by sparfloxacin. The Journal of the Association of Physicians of India, 2002, Volume: 50 Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Torsades de Pointes; Tuberculosis, Pulmonary	2002
Torsade de pointes probably induced by sparfloxain. The Journal of the Association of Physicians of India, 2003, Volume: 51 Topics: Adult; Diagnosis, Differential; Female; Fluoroquinolones; Humans; India; Long QT Syndrome; Torsades de Pointes; Tuberculosis, Pulmonary	2003
Comparison of sensitivity of surrogate markers of drug-induced torsades de pointes in canine hearts. European journal of pharmacology, 2004, Oct-11, Volume: 502, Issue:1-2 Topics: Action Potentials; Animals; Biomarkers; Dogs; Electrocardiography; Female; Fluoroquinolones; Heart; Heart Rate; Torsades de Pointes	2004
Calmodulin antagonist W-7 prevents sparfloxacin-induced early afterdepolarizations (EADs) in isolated rabbit purkinje fibers: importance of beat-to-beat instability of the repolarization. Journal of cardiovascular electrophysiology, 2006, Volume: 17, Issue:4 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Electrophysiologic Techniques, Cardiac; Enzyme Inhibitors; Female; Fluoroquinolones; Heart Rate; In Vitro Techniques; Purkinje Fibers; Rabbits; Sulfonamides; Torsades de Pointes	2006
Torsades de pointe probably related to sparfloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:4 Topics: Anti-Infective Agents; Female; Fluoroquinolones; Humans; Mastoiditis; Middle Aged; Otitis Media; Pneumococcal Infections; Quinolones; Torsades de Pointes	1996
Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades. Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1 Topics: Action Potentials; Animals; Anti-Infective Agents; Dogs; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart; Heart Block; Levofloxacin; Long QT Syndrome; Male; Models, Animal; Ofloxacin; Torsades de Pointes; Ventricular Dysfunction, Right	2000