Page last updated: 2024-08-24

sparfloxacin and Electrocardiogram QT Prolonged

sparfloxacin has been researched along with Electrocardiogram QT Prolonged in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Aimoto, M; Kawakami, S; Kurimoto, R; Nagasawa, Y; Sakai, K; Takahara, A1
Sugiyama, A1
Hashimoto, K; Satoh, Y; Sugiyama, A; Takahara, A1
Ahluwalia, G1
Chiba, K; Hashimoto, K; Sugiyama, A; Takasuna, K; Watanabe, K1
Chiba, K; Hashimoto, K; Satoh, Y; Shiina, H; Sugiyama, A1
Anderson, ME; Mazur, A; Roden, DM; Yang, T1

Reviews

1 review(s) available for sparfloxacin and Electrocardiogram QT Prolonged

ArticleYear
[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 121, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Antitubercular Agents; Cation Transport Proteins; Cisapride; Disease Models, Animal; Dogs; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gastrointestinal Agents; Haloperidol; Histamine H1 Antagonists; Long QT Syndrome; Potassium Channels; Potassium Channels, Voltage-Gated; Sulpiride; Terfenadine; Torsades de Pointes

2003

Other Studies

7 other study(ies) available for sparfloxacin and Electrocardiogram QT Prolonged

ArticleYear
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs.
    Journal of pharmacological sciences, 2020, Volume: 143, Issue:1

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Electrocardiography; Fluoroquinolones; Guinea Pigs; Halothane; Isoflurane; Long QT Syndrome; Male; Sevoflurane

2020
Effects of mexiletine on the canine model of sparfloxacin-induced long QT syndrome.
    European journal of pharmacology, 2003, Aug-22, Volume: 476, Issue:1-2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Blood Pressure; Bundle of His; Chromatography, High Pressure Liquid; Disease Models, Animal; Dogs; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Injections, Intravenous; Long QT Syndrome; Mexiletine; Refractory Period, Electrophysiological; Time Factors; Ventricular Function, Left

2003
Torsade de pointes probably induced by sparfloxain.
    The Journal of the Association of Physicians of India, 2003, Volume: 51

    Topics: Adult; Diagnosis, Differential; Female; Fluoroquinolones; Humans; India; Long QT Syndrome; Torsades de Pointes; Tuberculosis, Pulmonary

2003
Acute hypokalemia may not be an effective way to sensitize the in situ canine heart for sparfloxacin-induced long QT syndrome.
    Journal of pharmacological sciences, 2006, Volume: 100, Issue:1

    Topics: Animals; Antitubercular Agents; Dogs; Drug Evaluation, Preclinical; Female; Fluoroquinolones; Furosemide; Heart Conduction System; Hypokalemia; Long QT Syndrome; Models, Animal; Time Factors

2006
Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades.
    Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1

    Topics: Action Potentials; Animals; Anti-Infective Agents; Dogs; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart; Heart Block; Levofloxacin; Long QT Syndrome; Male; Models, Animal; Ofloxacin; Torsades de Pointes; Ventricular Dysfunction, Right

2000
Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Arrhythmias, Cardiac; Aza Compounds; Cation Transport Proteins; DNA-Binding Proteins; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gatifloxacin; Long QT Syndrome; Mice; Models, Animal; Moxifloxacin; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinolines; Rabbits; Trans-Activators; Tumor Cells, Cultured

2001