spa-s-843 and Cryptococcosis

spa-s-843 has been researched along with Cryptococcosis* in 2 studies

Other Studies

2 other study(ies) available for spa-s-843 and Cryptococcosis

Article	Year
Efficacy of SPK-843, a novel polyene antifungal, in a murine model of systemic cryptococcosis. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 SPK-843, a new polyene antifungal, possessed efficacy in a murine model of systemic infection caused by Cryptococcus neoformans. The administration of 4.0 mg/kg SPK-843 led to better survival prolongation and fungal reduction than those observed with the administration of 0.7 mg/kg amphotericin B and 80 mg/kg fluconazole (P < 0.001), without histopathological renal changes. Topics: Animals; Antifungal Agents; Brain; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Polyenes	2008
In vitro activity of a new polyene SPK-843 against Candida spp, Cryptococcus neoformans and Aspergillus spp clinical isolates. Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:3 Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Multiple, Fungal; Humans; Italy; Microbial Sensitivity Tests; Polyenes; Sensitivity and Specificity	2003

Article

Year

Efficacy of SPK-843, a novel polyene antifungal, in a murine model of systemic cryptococcosis.

Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

SPK-843, a new polyene antifungal, possessed efficacy in a murine model of systemic infection caused by Cryptococcus neoformans. The administration of 4.0 mg/kg SPK-843 led to better survival prolongation and fungal reduction than those observed with the administration of 0.7 mg/kg amphotericin B and 80 mg/kg fluconazole (P < 0.001), without histopathological renal changes.

Topics: Animals; Antifungal Agents; Brain; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Polyenes

2008

In vitro activity of a new polyene SPK-843 against Candida spp, Cryptococcus neoformans and Aspergillus spp clinical isolates.

Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:3

Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Multiple, Fungal; Humans; Italy; Microbial Sensitivity Tests; Polyenes; Sensitivity and Specificity

2003