spa-s-132 and Brain-Diseases

spa-s-132 has been researched along with Brain-Diseases* in 1 studies

Other Studies

1 other study(ies) available for spa-s-132 and Brain-Diseases

Article	Year
Potent antifungal effects of a new derivative of partricin A in a murine model of cerebral cryptococcosis. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3 A new member of the polyene family, N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate (SPA), was investigated and was found to be more effective than amphotericin B (i) in vivo by enhancing mouse resistance to cryptococcal meningoencephalitis and (ii) in vitro by potentiating the anticryptococcal activity of murine microglial cells. Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Brain Diseases; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Meningitis, Cryptococcal; Mice; Polyenes	1997

Article

Year

Potent antifungal effects of a new derivative of partricin A in a murine model of cerebral cryptococcosis.

Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3

A new member of the polyene family, N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate (SPA), was investigated and was found to be more effective than amphotericin B (i) in vivo by enhancing mouse resistance to cryptococcal meningoencephalitis and (ii) in vitro by potentiating the anticryptococcal activity of murine microglial cells.

Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Brain Diseases; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Meningitis, Cryptococcal; Mice; Polyenes

1997