sotalol has been researched along with Tremor in 9 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Log dose-response curves for increases in both heart rate (mostly beta 1), and amplitude of physiologic tremor (beta 2) were constructed for each subject in the control state and 2 hr after 10 or 40 mg propranolol, 200 mg sotalol, or placebo." | 9.05 | Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremor. ( Fish, A; Perucca, E; Pickles, H; Richens, A, 1981) |
| "In order to elucidate the mode of action of beta-adrenoreceptor antagonists in essential tremor, the efficacy of chronic oral administration of metoprolol, atenolol and sotalol was compared in a randomised, double-blind placebo controlled trial in twenty-four patients." | 9.05 | Beta-adrenoreceptor mechanisms in essential tremor; a double-blind placebo controlled trial of metoprolol, sotalol and atenolol. ( Jefferson, D; Leigh, PN; Marsden, CD; Twomey, A, 1983) |
| "The effects of intravenous doses of propranolol, sotalol, timolol, atenolol and placebo on exercise-induced tachycardia and exercise-induced increases in hand tremor were assessed in four healthy volunteers." | 5.06 | Exercise-induced hand tremor: a possible test for beta 2-adrenoceptor selectivity in man? ( Abila, B; Marshall, RW; Richens, A; Wilson, JF, 1986) |
| " Log dose-response curves for increases in both heart rate (mostly beta 1), and amplitude of physiologic tremor (beta 2) were constructed for each subject in the control state and 2 hr after 10 or 40 mg propranolol, 200 mg sotalol, or placebo." | 5.05 | Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremor. ( Fish, A; Perucca, E; Pickles, H; Richens, A, 1981) |
| "In order to elucidate the mode of action of beta-adrenoreceptor antagonists in essential tremor, the efficacy of chronic oral administration of metoprolol, atenolol and sotalol was compared in a randomised, double-blind placebo controlled trial in twenty-four patients." | 5.05 | Beta-adrenoreceptor mechanisms in essential tremor; a double-blind placebo controlled trial of metoprolol, sotalol and atenolol. ( Jefferson, D; Leigh, PN; Marsden, CD; Twomey, A, 1983) |
| "Three different beta-adrenoreceptor antagonists--propranolol, sotalol, and atenolol--were compared in a double-blind study with placebo in nine patients with essential tremor." | 5.04 | beta-Adrenoreceptor antagonists in essential tremor. ( Jefferson, D; Jenner, P; Marsden, CD, 1979) |
| "The effect of beta-adrenoceptor antagonists, varying in lipophilicity and receptor selectivity, were studied on tremor elicited by L-5-hydroxytryptophan (L-5-HTP) in rats pretreated with a peripherally acting decarboxylase inhibitor and a monoamine oxidase inhibitor, or by the directly acting 5-HT agonist 5-methoxy-N,N-dimethyltryptamine (5-MeODMT)." | 3.67 | Blockade of central beta-adrenoceptors attenuates tremor induced by 5-hydroxytryptamine (5-HT)-receptor activation in rats. ( Hallberg, H, 1987) |
| " The dose-response curves constructed with intra-arterial or intravenous isoprenaline behave similarly in the presence of both atenolol 50 mg and propranolol 40 mg." | 1.27 | Enhancement of physiological finger tremor by intravenous isoprenaline infusions in man: evaluation of its role in the assessment of beta-adrenoceptor antagonists. ( Arnold, JM; McDevitt, DG, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leigh, PN | 2 |
| Marsden, CD | 3 |
| Twomey, A | 2 |
| Jefferson, D | 3 |
| Pickles, H | 1 |
| Perucca, E | 1 |
| Fish, A | 1 |
| Richens, A | 2 |
| Gerstenbrand, F | 1 |
| Klingler, D | 1 |
| Poewe, W | 1 |
| Arnold, JM | 1 |
| McDevitt, DG | 1 |
| Jenner, P | 1 |
| Abila, B | 1 |
| Wilson, JF | 1 |
| Marshall, RW | 1 |
| Hallberg, H | 1 |
| Whitlock, FA | 1 |
| Price, J | 1 |
1 review available for sotalol and Tremor
| Article | Year |
|---|---|
Use of beta-adrenergic receptor blocking drugs in psychiatry.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Di | 1974 |
5 trials available for sotalol and Tremor
| Article | Year |
|---|---|
beta-Adrenoceptor antagonists and essential tremor.
Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprol | 1981 |
Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremor.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Dose-Response Relationship, Drug; Female; | 1981 |
Beta-adrenoreceptor mechanisms in essential tremor; a double-blind placebo controlled trial of metoprolol, sotalol and atenolol.
Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans | 1983 |
beta-Adrenoreceptor antagonists in essential tremor.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Place | 1979 |
Exercise-induced hand tremor: a possible test for beta 2-adrenoceptor selectivity in man?
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Hand; Heart Rate; Humans; Male; Physical Exertion; Pro | 1986 |
3 other studies available for sotalol and Tremor
| Article | Year |
|---|---|
[Therapy of essential tremor with special reference to the use of beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bupranolol; Double-Blind Method; Female; Humans; | 1982 |
Enhancement of physiological finger tremor by intravenous isoprenaline infusions in man: evaluation of its role in the assessment of beta-adrenoceptor antagonists.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Dose-Response Relationship | 1984 |
Blockade of central beta-adrenoceptors attenuates tremor induced by 5-hydroxytryptamine (5-HT)-receptor activation in rats.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Male; M | 1987 |