Page last updated: 2024-11-04

sotalol and Syncope

sotalol has been researched along with Syncope in 22 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
" The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy."7.75Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009)
"Thirteen patients developed syncope and a prolonged QTc interval while taking therapeutic doses of sotalol."7.67Sotalol, hypokalaemia, syncope, and torsade de pointes. ( Barlow, JB; McKibbin, JK; Millar, RN; Obel, IW; Pocock, WA, 1984)
"Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide."5.10Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002)
" The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy."3.75Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009)
"Thirteen patients developed syncope and a prolonged QTc interval while taking therapeutic doses of sotalol."3.67Sotalol, hypokalaemia, syncope, and torsade de pointes. ( Barlow, JB; McKibbin, JK; Millar, RN; Obel, IW; Pocock, WA, 1984)
"Arrhythmogenic right ventricular dysplasia is an inherited, progressive condition."1.31Arrhythmogenic right ventricular dysplasia. An illustrated review highlighting developments in the diagnosis and management of this potentially fatal condition. ( Fisher, NG; Gilbert, TJ, 2000)
"Ventricular arrhythmias play an important role in the pathophysiologic aspects of sudden cardiac death."1.27Identification of patients at high risk for sudden cardiac death. ( Bigger, JT, 1984)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's5 (22.73)18.2507
2000's8 (36.36)29.6817
2010's3 (13.64)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Reynolds, MR1
Bunch, TJ1
Steinberg, BA1
Ronk, CJ1
Kim, H1
Wieloch, M1
Lip, GYH1
Chatterjee, D1
DeLillo, DM1
Jesty, SA1
Souza, MJ1
Conte, G1
Sieira, J1
Ciconte, G1
de Asmundis, C1
Chierchia, GB1
Baltogiannis, G1
Di Giovanni, G1
La Meir, M1
Wellens, F1
Czapla, J1
Wauters, K1
Levinstein, M1
Saitoh, Y1
Irfan, G1
Julià, J1
Pappaert, G1
Brugada, P1
Ferasin, L1
Keivanidou, A1
Arnaoutoglou, C1
Krommydas, A1
Papanikolaou, G1
Tsiptses, K1
Chrisopoulos, C1
Kirpizidis, C1
Er, F1
Nia, AM1
Erdmann, E1
Meurs, KM1
Spier, AW1
Wright, NA1
Atkins, CE1
DeFrancesco, TC1
Gordon, SG1
Hamlin, RL1
Keene, BW1
Miller, MW1
Moise, NS1
Zakrzewska, A1
Makowska, AM1
Górnicka, B1
Szostek, M1
Bar-Andziak, E1
Binder, WD1
Fifer, MA1
King, ME1
Stone, JR1
Laakso, M1
Pentikäinen, PJ1
Pyörälä, K1
Neuvonen, PJ1
McKibbin, JK1
Pocock, WA1
Barlow, JB1
Millar, RN1
Obel, IW1
Bigger, JT1
Antonaccio, MJ1
Lessem, JN1
Soyka, LF1
Kuck, KH1
Kunze, KP1
Roewer, N1
Bleifeld, W1
Galatius-Jensen, S1
Clemmensen, PM1
Pietersen, AH1
Nielsen, HV1
Makkar, RR1
Fromm, BS1
Steinman, RT1
Meissner, MD1
Lehmann, MH1
de Meester, A1
Chaudron, JM1
de Roy, L1
Panhuyzen-Goedkoop, NM1
Crijns, HJ1
Tarantini, G1
Menti, L1
Angelini, A1
Martini, B1
Thiene, G1
Daliento, L1
Fisher, NG1
Gilbert, TJ1
Kuntz, RE1
Ruskin, JN1
Weinberger, S1
Lorell, BH1

Reviews

1 review available for sotalol and Syncope

ArticleYear
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
    JAMA, 1993, Dec-01, Volume: 270, Issue:21

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramid

1993

Trials

1 trial available for sotalol and Syncope

ArticleYear
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
    Journal of the American Veterinary Medical Association, 2002, Aug-15, Volume: 221, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C

2002

Other Studies

20 other studies available for sotalol and Syncope

ArticleYear
Novel methodology for the evaluation of symptoms reported by patients with newly diagnosed atrial fibrillation: Application of natural language processing to electronic medical records data.
    Journal of cardiovascular electrophysiology, 2023, Volume: 34, Issue:4

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Dizziness; Dronedarone; Dyspnea; Electronic Heal

2023
A case of palpitation and pre-syncope.
    BMJ (Clinical research ed.), 2017, 05-24, Volume: 357

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Sotalol; Sy

2017
Episodic syncope caused by ventricular flutter in a tiger (Panthera tigris).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2013, Volume: 44, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Lidocaine; Male; Panthera; Sotalol; Syncope; Ventricular Flutter

2013
Implantable cardioverter-defibrillator therapy in Brugada syndrome: a 20-year single-center experience.
    Journal of the American College of Cardiology, 2015, Mar-10, Volume: 65, Issue:9

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Belgium; Brugada Syndr

2015
Recurrent syncope associated with paroxysmal supraventricular tachycardia in a Devon Rex cat diagnosed by implantable loop recorder.
    Journal of feline medicine and surgery, 2009, Volume: 11, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Cat Diseases; Cats; Electrocardiography, Ambulatory; Male; Sotalol;

2009
Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy.
    Cardiology journal, 2009, Volume: 16, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents; Atrial Fibrillation; Ciprofloxacin;

2009
[79-year-old patient with paroxysmal artial fibrillation and syncope].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:45

    Topics: Aged; Antihypertensive Agents; Atrial Fibrillation; Diagnosis, Differential; Electrocardiography; Hu

2009
[Dramatic symptoms of pheochromocytoma in old woman during antiarrhythmic therapy with sotalol: case report].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 15, Issue:85

    Topics: Adrenal Gland Neoplasms; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Diagnosis, Differential; F

2003
Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging.
    The New England journal of medicine, 2005, Aug-25, Volume: 353, Issue:8

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Diagnosis, Differentia

2005
Prolongation of the Q-T interval caused by sotalol--possible association with ventricular tachyarrhythmias.
    European heart journal, 1981, Volume: 2, Issue:4

    Topics: Adrenergic beta-Antagonists; Atenolol; Electrocardiography; Heart Ventricles; Humans; Kinetics; Male

1981
Sotalol, hypokalaemia, syncope, and torsade de pointes.
    British heart journal, 1984, Volume: 51, Issue:2

    Topics: Adult; Aged; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; H

1984
Identification of patients at high risk for sudden cardiac death.
    The American journal of cardiology, 1984, Nov-14, Volume: 54, Issue:9

    Topics: Anilides; Arrhythmias, Cardiac; Death, Sudden; Encainide; Heart; Heart Ventricles; Humans; Prognosis

1984
Sotalol, hypokalaemia, syncope, and torsade de pointes.
    British heart journal, 1984, Volume: 52, Issue:3

    Topics: Aged; Humans; Hypokalemia; Sotalol; Syncope; Tachycardia

1984
Sotalol-induced torsade de pointes.
    American heart journal, 1984, Volume: 107, Issue:1

    Topics: Adult; Electrocardiography; Female; Humans; Sotalol; Syncope; Tachycardia

1984
[Diagnosis of long QT syndrome with the help of atropine provoked ventricular tachycardia].
    Ugeskrift for laeger, 1994, Jan-31, Volume: 156, Issue:5

    Topics: Atropine; Electrocardiography; Female; Humans; Injections, Intravenous; Long QT Syndrome; Middle Age

1994
Usefulness of isoproterenol in the induction of clinical sustained ventricular tachycardia during electrophysiological study.
    Acta cardiologica, 1997, Volume: 52, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Atenolol; Cardiac Pacing, Artificial; E

1997
[Iatrogenic collapse; can this be prevented?].
    Nederlands tijdschrift voor geneeskunde, 1997, Feb-08, Volume: 141, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Disopyramide; Erythro

1997
Life-threatening ventricular arrhythmias associated with giant cell myocarditis (possibly sarcoidosis).
    The American journal of cardiology, 2000, May-15, Volume: 85, Issue:10

    Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Diagnosis, Differential; Female; Humans; Middle Ag

2000
Arrhythmogenic right ventricular dysplasia. An illustrated review highlighting developments in the diagnosis and management of this potentially fatal condition.
    Postgraduate medical journal, 2000, Volume: 76, Issue:897

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Arrhythmogenic Right Ventric

2000
The advantage of d-sotalol over dl-sotalol in a patient with ventricular arrhythmias and comorbid bronchospasm.
    Chest, 1992, Volume: 102, Issue:5

    Topics: Bronchial Spasm; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Sotalol; Stereoisomerism; Sy

1992