sotalol has been researched along with Renal Insufficiency in 4 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Due to risk of serious adverse drug events (ADEs) sotalol use is limited in renal insufficiency and heart failure." | 3.77 | Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement. ( Finks, SW; Manguso, AH; Rogers, KC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mulder, VC | 1 |
| Oudemans-Van Straaten, HM | 1 |
| Zandstra, DF | 1 |
| Franssen, EJ | 1 |
| Finks, SW | 1 |
| Rogers, KC | 1 |
| Manguso, AH | 1 |
| Dancey, D | 1 |
| Wulffhart, Z | 1 |
| McEwan, P | 1 |
| van Uum, SH | 1 |
| van den Merkhof, LF | 1 |
| Lucassen, AM | 1 |
| Wuis, EW | 1 |
| Diemont, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety Assessment for Sotalol Protocol in Outpatient Unit[NCT05418036] | Phase 4 | 110 participants (Anticipated) | Interventional | 2020-10-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for sotalol and Renal Insufficiency
| Article | Year |
|---|---|
Massive ingestion of cardiac drugs: toxicokinetic aspects of digoxin and sotalol during hemofiltration.
Topics: Aged; Anti-Arrhythmia Agents; Digoxin; Hemofiltration; Humans; Immunoglobulin Fab Fragments; Male; R | 2010 |
Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Dr | 2011 |
Sotalol-induced torsades de pointes in patients with renal failure.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Electrocardiography; F | 1997 |
Successful haemodialysis in sotalol-induced torsade de pointes in a patient with progressive renal failure.
Topics: Adrenergic beta-Antagonists; Humans; Male; Middle Aged; Renal Dialysis; Renal Insufficiency; Sotalol | 1997 |