sotalol has been researched along with Paroxysmal Reciprocal Tachycardia in 19 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a randomized, double-blind, placebo-controled, parallel-group comparison study of the efficacy and safety of sotalol in the prophylaxis of paroxysmal supraventricular tachyarrhythmias (PSVTs) (including paroxysmal atrial fibrillation and paroxysmal reentrant SVTs)." | 9.08 | Multicenter comparative study of the efficacy and safety of sotalol in the prophylactic treatment of patients with paroxysmal supraventricular tachyarrhythmias. ( Anderson, K; Joseph, SP; Joy, M; Wanless, RS, 1997) |
| "This study investigated the hemodynamic effects of oral sotalol during both sinus rhythm and paroxysmal atrial fibrillation." | 9.07 | Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation. ( Alboni, P; Chioin, R; Fucà, G; Paparella, N; Pedini, I; Razzolini, R; Scarfò, S, 1993) |
| "This study was designed to evaluate and compare the effects of oral sotalol for the treatment of vagal and adrenergic paroxysmal atrial fibrillation (PAF)." | 7.70 | Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation. ( Aslan, O; Bayata, S; Postaci, N; Yeşil, M; Yücel, O, 1999) |
| "In conclusion, for patients with paroxysmal atrial fibrillation admitted for dofetilide or sotalol loading, T-wave markers of increased repolarization heterogeneity are measurable within hours after initiation." | 5.40 | Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation. ( Dorsey, P; Hayes, M; Kaplan, R; Passman, R; Sauer, AJ; Shah, SJ; Xue, J, 2014) |
| "We performed a randomized, double-blind, placebo-controled, parallel-group comparison study of the efficacy and safety of sotalol in the prophylaxis of paroxysmal supraventricular tachyarrhythmias (PSVTs) (including paroxysmal atrial fibrillation and paroxysmal reentrant SVTs)." | 5.08 | Multicenter comparative study of the efficacy and safety of sotalol in the prophylactic treatment of patients with paroxysmal supraventricular tachyarrhythmias. ( Anderson, K; Joseph, SP; Joy, M; Wanless, RS, 1997) |
| "This study investigated the hemodynamic effects of oral sotalol during both sinus rhythm and paroxysmal atrial fibrillation." | 5.07 | Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation. ( Alboni, P; Chioin, R; Fucà, G; Paparella, N; Pedini, I; Razzolini, R; Scarfò, S, 1993) |
| "This study was designed to evaluate and compare the effects of oral sotalol for the treatment of vagal and adrenergic paroxysmal atrial fibrillation (PAF)." | 3.70 | Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation. ( Aslan, O; Bayata, S; Postaci, N; Yeşil, M; Yücel, O, 1999) |
| "The indication to treat symptomatic paroxysmal atrial fibrillation is discussed controversely." | 2.69 | [Medicamentous prevention of symptomatic paroxysmal atrial fibrillation/flutter onset. Goals and design of the SOPAT Study. Executive committee of the investigators representing trial physicians]. ( Koch, HP; Lüderitz, B; Meinertz, T; Patten, M; Sonntag, F, 1999) |
| " A total of 15 possible adverse effects were reported, occurring in 10 patients with sotalol versus 4 with placebo." | 2.67 | Efficacy and safety of intravenous sotalol for termination of paroxysmal supraventricular tachycardia. The Sotalol Versus Placebo Multicenter Study Group. ( Gorgels, A; Jordaens, L; Stroobandt, R; Temmerman, J, 1991) |
| "In conclusion, for patients with paroxysmal atrial fibrillation admitted for dofetilide or sotalol loading, T-wave markers of increased repolarization heterogeneity are measurable within hours after initiation." | 1.40 | Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation. ( Dorsey, P; Hayes, M; Kaplan, R; Passman, R; Sauer, AJ; Shah, SJ; Xue, J, 2014) |
| "2% after intravenous d-sotalol, but no adverse symptoms developed." | 1.28 | Efficacy, safety, and tolerance of d-sotalol in patients with refractory supraventricular tachyarrhythmias. ( Bigger, JT; Kidwell, GA; Reiffel, JA; Sahar, DI; Squatrito, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sauer, AJ | 1 |
| Kaplan, R | 1 |
| Xue, J | 1 |
| Dorsey, P | 1 |
| Hayes, M | 1 |
| Shah, SJ | 1 |
| Passman, R | 1 |
| Tereshchenko, SN | 1 |
| Uteshev, IuA | 1 |
| Morozova, MN | 1 |
| Chuich, NG | 1 |
| Kochetov, AG | 1 |
| Liakishev, AA | 1 |
| Rizos, I | 1 |
| Senges, J | 1 |
| Jauernig, R | 1 |
| Lengfelder, W | 1 |
| Czygan, E | 1 |
| Brachmann, J | 1 |
| Kübler, W | 1 |
| Hamer, AW | 1 |
| Strathmore, N | 1 |
| Vohra, JK | 1 |
| Hunt, VD | 1 |
| Gutiérrez-Larraya, F | 1 |
| Jabón, A | 1 |
| Manz, M | 1 |
| Lüderitz, B | 2 |
| Alboni, P | 1 |
| Razzolini, R | 1 |
| Scarfò, S | 1 |
| Paparella, N | 1 |
| Fucà, G | 1 |
| Pedini, I | 1 |
| Chioin, R | 1 |
| Wanless, RS | 1 |
| Anderson, K | 1 |
| Joy, M | 1 |
| Joseph, SP | 1 |
| Heisel, A | 1 |
| Jung, J | 1 |
| Neuzner, J | 1 |
| Schieffer, H | 1 |
| Fröhlig, G | 1 |
| Basta, M | 1 |
| Klein, GJ | 1 |
| Yee, R | 1 |
| Krahn, A | 1 |
| Lee, J | 1 |
| Patten, M | 1 |
| Koch, HP | 1 |
| Sonntag, F | 1 |
| Meinertz, T | 1 |
| Yeşil, M | 1 |
| Bayata, S | 1 |
| Postaci, N | 1 |
| Yücel, O | 1 |
| Aslan, O | 1 |
| Inama, G | 1 |
| Furlanello, F | 1 |
| Vergara, G | 1 |
| Guarnerio, M | 1 |
| Braito, G | 1 |
| Nassivera, E | 1 |
| Jordaens, L | 1 |
| Gorgels, A | 1 |
| Stroobandt, R | 1 |
| Temmerman, J | 1 |
| Camm, AJ | 1 |
| Paul, V | 1 |
| Sahar, DI | 1 |
| Reiffel, JA | 1 |
| Bigger, JT | 1 |
| Squatrito, A | 1 |
| Kidwell, GA | 1 |
| Ramsdale, DR | 1 |
| Peterson, C | 1 |
| Gettes, LS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety Assessment for Sotalol Protocol in Outpatient Unit[NCT05418036] | Phase 4 | 110 participants (Anticipated) | Interventional | 2020-10-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for sotalol and Paroxysmal Reciprocal Tachycardia
| Article | Year |
|---|---|
[Tachycardias: considerations in childhood in the 90s].
Topics: Adenosine; Adolescent; Adult; Amiodarone; Atrial Flutter; Child; Child, Preschool; Electrocardiograp | 1993 |
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Fle | 1993 |
Current role of pharmacologic therapy for patients with paroxysmal supraventricular tachycardia.
Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Calcium Channel Blockers; Digoxin; El | 1997 |
Sotalol for paroxysmal supraventricular tachycardias.
Topics: Double-Blind Method; Humans; Randomized Controlled Trials as Topic; Sotalol; Tachycardia, Paroxysmal | 1990 |
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillatio | 1970 |
9 trials available for sotalol and Paroxysmal Reciprocal Tachycardia
| Article | Year |
|---|---|
[Effect of bisoprolol and sotalol on clinical status of patients with proximal form of atrial fibrillation and chronic heart failure].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Fibrillation; Bisoprolol; Exercise Test; Female; He | 2007 |
[Circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation. Results of the APAF trial].
Topics: Adolescent; Adult; Aged; Amiodarone; Angina, Unstable; Anti-Arrhythmia Agents; Atrial Fibrillation; | 2008 |
Oral flecainide, sotalol, and verapamil for the termination of paroxysmal supraventricular tachycardia.
Topics: Administration, Oral; Adult; Cardiac Pacing, Artificial; Female; Flecainide; Humans; Male; Middle Ag | 1993 |
Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation.
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Cardiac Catheterization; Cardiac Pacing, Art | 1993 |
Multicenter comparative study of the efficacy and safety of sotalol in the prophylactic treatment of patients with paroxysmal supraventricular tachyarrhythmias.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; D | 1997 |
[Medicamentous prevention of symptomatic paroxysmal atrial fibrillation/flutter onset. Goals and design of the SOPAT Study. Executive committee of the investigators representing trial physicians].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dose-Response Relationship, Drug; Doubl | 1999 |
[Sotalol in the Wolff-Parkinson-White syndrome: an electrophysiological and clinical study].
Topics: Adult; Atrial Fibrillation; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Fema | 1992 |
Efficacy and safety of intravenous sotalol for termination of paroxysmal supraventricular tachycardia. The Sotalol Versus Placebo Multicenter Study Group.
Topics: Adult; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Injections, Intravenous; Mal | 1991 |
Sotalol for paroxysmal supraventricular tachycardias.
Topics: Double-Blind Method; Humans; Randomized Controlled Trials as Topic; Sotalol; Tachycardia, Paroxysmal | 1990 |
6 other studies available for sotalol and Paroxysmal Reciprocal Tachycardia
| Article | Year |
|---|---|
Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation.
Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Diagnosis, Computer- | 2014 |
Differential effects of sotalol and metoprolol on induction of paroxysmal supraventricular tachycardia.
Topics: Adult; Aged; Atrioventricular Node; Female; Humans; Male; Metoprolol; Middle Aged; Recurrence; Sotal | 1984 |
[Biatrial stimulation in therapy of paroxysmal atrial tachycardia: a case report].
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function; Combined Modalit | 1997 |
Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrilla | 1999 |
Efficacy, safety, and tolerance of d-sotalol in patients with refractory supraventricular tachyarrhythmias.
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Female; | 1989 |
Successful termination of combined rapid atrial flutter/fibrillation and ventricular tachycardia by intravenous sotalol.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Humans; Infusions | 1987 |