Page last updated: 2024-11-04

sotalol and Mitral Stenosis

sotalol has been researched along with Mitral Stenosis in 1 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
"Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors."1.28Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. ( Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodde, OE1
Zerkowski, HR1
Borst, HG1
Maier, W1
Michel, MC1

Other Studies

1 other study available for sotalol and Mitral Stenosis

ArticleYear
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
    European heart journal, 1989, Volume: 10 Suppl B

    Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure

1989