Page last updated: 2024-11-04

sotalol and Marfan Syndrome

sotalol has been researched along with Marfan Syndrome in 1 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2.

Research Excerpts

ExcerptRelevanceReference
"Sotalol was partially effective for AVRT, however, it did not prevent AF, RF ablation cured all arrythmias."5.35[Sotalol prevents atrio-ventricular tachycardia but not atrial fibrillation with rapid ventricular response in a patient wiht WPW syndrome]. ( Bodalski, R; Orczykowski, M; Szufladowicz, E; Szumowski, L; Walczak, F; Zakrzewska-Koperska, J, 2008)
"Sotalol was partially effective for AVRT, however, it did not prevent AF, RF ablation cured all arrythmias."1.35[Sotalol prevents atrio-ventricular tachycardia but not atrial fibrillation with rapid ventricular response in a patient wiht WPW syndrome]. ( Bodalski, R; Orczykowski, M; Szufladowicz, E; Szumowski, L; Walczak, F; Zakrzewska-Koperska, J, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orczykowski, M1
Szumowski, L1
Szufladowicz, E1
Bodalski, R1
Zakrzewska-Koperska, J1
Walczak, F1

Other Studies

1 other study available for sotalol and Marfan Syndrome

ArticleYear
[Sotalol prevents atrio-ventricular tachycardia but not atrial fibrillation with rapid ventricular response in a patient wiht WPW syndrome].
    Kardiologia polska, 2008, Volume: 66, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Catheter Ablation; Electrocardiography; Humans; Male; Marfan Syndrome

2008