sotalol has been researched along with Kidney Failure, Chronic in 7 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The assay procedure has been successfully used during pharmacokinetic studies in healthy volunteers and patients as well as during toxicokinetic analysis." | 1.27 | Determination of sotalol in human body fluids for pharmacokinetic and toxicokinetic studies using high-performance liquid chromatography. ( Braun, J; Geldmacher-von Mallinckrodt, M; Gluth, B; Gluth, WP; Sörgel, F, 1988) |
| " For an anuric patient, serum half-life was calculated to be 69 h." | 1.26 | Pharmacokinetics of sotalol after chronic administration to patients with renal insufficiency. ( Berglund, G; Descamps, R; Thomis, JA, 1980) |
| " Since beta-blockers may impair renal function, even in therapeutic concentrations, the dosage of sotalol, in particular, must be reduced in patient with kidney disease." | 1.25 | Serum levels and half-life of sotalol in chronic renal failure. ( Anttila, M; Forsström, J; Kasanen, A; Sundquist, HK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kontopoulos, A | 1 |
| Filindris, A | 1 |
| Manoudis, F | 1 |
| Metaxas, P | 1 |
| Berglund, G | 1 |
| Descamps, R | 1 |
| Thomis, JA | 1 |
| Blair, AD | 1 |
| Burgess, ED | 1 |
| Maxwell, BM | 1 |
| Cutler, RE | 1 |
| Patrick, GM | 1 |
| Pollock, CA | 1 |
| Ibels, LS | 1 |
| Caterson, RJ | 1 |
| Tjandramaga, TB | 1 |
| Verbeeck, R | 1 |
| Thomas, J | 1 |
| Verbesselt, R | 1 |
| Verberckmoes, R | 1 |
| Schepper, PJ | 1 |
| Sundquist, HK | 1 |
| Anttila, M | 1 |
| Forsström, J | 1 |
| Kasanen, A | 1 |
| Gluth, WP | 1 |
| Sörgel, F | 1 |
| Gluth, B | 1 |
| Braun, J | 1 |
| Geldmacher-von Mallinckrodt, M | 1 |
7 other studies available for sotalol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Satalol-induced torsade de pointes.
Topics: Adult; Humans; Kidney Failure, Chronic; Male; Sotalol; Tachycardia | 1981 |
Pharmacokinetics of sotalol after chronic administration to patients with renal insufficiency.
Topics: Aged; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney Failure, | 1980 |
Sotalol kinetics in renal insufficiency.
Topics: Adult; Aged; Creatinine; Humans; Kidney Failure, Chronic; Kinetics; Middle Aged; Renal Dialysis; Sot | 1981 |
Sotalol and end-stage renal failure.
Topics: Aged; Atrial Fibrillation; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Sotalol | 1994 |
The effect of end-stage renal failure and haemodialysis on the elimination kinetics of sotalol.
Topics: Adult; Half-Life; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Sotalol | 1976 |
Serum levels and half-life of sotalol in chronic renal failure.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Creatinine; Female; Half-Life; Humans; Kidney Fai | 1975 |
Determination of sotalol in human body fluids for pharmacokinetic and toxicokinetic studies using high-performance liquid chromatography.
Topics: Biological Availability; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Kidn | 1988 |