sotalol has been researched along with Kidney Diseases in 3 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Very slight accumulation of sotalol and hydrochlorothiazide was observed, so it appears unnecessary to reduce the dosage in patients with a creatinine clearance of 30 ml/min or more." | 1.27 | Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency. ( Fillastre, JP; Fourtillan, JB; Ingrand, I; Kher, A; Lefebvre, MA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A | 1 |
| Tam, KY | 1 |
| Kher, A | 1 |
| Fillastre, JP | 1 |
| Fourtillan, JB | 1 |
| Lefebvre, MA | 1 |
| Ingrand, I | 1 |
| Dumas, M | 1 |
| d'Athis, P | 1 |
| Besancenot, JF | 1 |
| Chadoint-Noudeau, V | 1 |
| Chalopin, JM | 1 |
| Rifle, G | 1 |
| Escousse, A | 1 |
3 other studies available for sotalol and Kidney Diseases
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological | 2010 |
Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency.
Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Kinetics; Sotalol | 1984 |
Variations of sotalol kinetics in renal insufficiency.
Topics: Arrhythmias, Cardiac; Creatinine; Half-Life; Humans; Kidney Diseases; Risk Factors; Sotalol | 1989 |