sotalol has been researched along with Injury, Myocardial Reperfusion in 5 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 7.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "The effect of (+/-)-sotalol (a beta-blocker with class III antiarrhythmic activity) against reperfusion-induced arrhythmias was studied in artificially ventilated, open-chest, Sprague-Dawley and Wistar rats." | 7.67 | Effect of sotalol against reperfusion-induced arrhythmias in Sprague-Dawley and Wistar rats. ( De Champlain, J; Lamontagne, D; Nadeau, R; Rochette, L; Vermeulen, M; Yamaguchi, N, 1989) |
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 3.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "The effect of (+/-)-sotalol (a beta-blocker with class III antiarrhythmic activity) against reperfusion-induced arrhythmias was studied in artificially ventilated, open-chest, Sprague-Dawley and Wistar rats." | 3.67 | Effect of sotalol against reperfusion-induced arrhythmias in Sprague-Dawley and Wistar rats. ( De Champlain, J; Lamontagne, D; Nadeau, R; Rochette, L; Vermeulen, M; Yamaguchi, N, 1989) |
| "Duration of ventricular tachycardia (VT) episodes was reduced from 15." | 1.37 | First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model. ( Bhandari, A; Dow, JS; Kloner, RA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koini, EN | 1 |
| Papazafiri, P | 1 |
| Vassilopoulos, A | 1 |
| Koufaki, M | 1 |
| Horváth, Z | 1 |
| Koncz, I | 1 |
| Virág, L | 1 |
| Papp, GJ | 1 |
| Varró, A | 1 |
| Calogeropoulou, T | 1 |
| Kloner, RA | 1 |
| Dow, JS | 1 |
| Bhandari, A | 1 |
| Bellemin-Baurreau, J | 1 |
| Poizot, A | 1 |
| Hicks, PE | 1 |
| Armstrong, JM | 1 |
| Manning, AS | 1 |
| Bruyninckx, C | 1 |
| Ramboux, J | 1 |
| Chatelain, P | 1 |
| Lamontagne, D | 1 |
| Rochette, L | 1 |
| Vermeulen, M | 1 |
| Yamaguchi, N | 1 |
| Nadeau, R | 1 |
| De Champlain, J | 1 |
5 other studies available for sotalol and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
5,7,8-Trimethyl-benzopyran and 5,7,8-trimethyl-1,4-benzoxazine aminoamide derivatives as novel antiarrhythmics against ischemia-reperfusion injury.
Topics: Action Potentials; Amides; Animals; Anti-Arrhythmia Agents; Antioxidants; Benzopyrans; Benzoxazines; | 2009 |
First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model.
Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Female; Infusions, Intravenous; In | 2011 |
An in vitro method for the evaluation of antiarrhythmic and antiischemic agents by using programmed electrical stimulation of rabbit heart.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Glycine; Heart; | 1994 |
SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans | 1995 |
Effect of sotalol against reperfusion-induced arrhythmias in Sprague-Dawley and Wistar rats.
Topics: Animals; Arrhythmias, Cardiac; Electrophysiology; Hemodynamics; In Vitro Techniques; Male; Myocardia | 1989 |