sotalol has been researched along with Hypoxia in 8 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 7.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 3.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| "Experimental induction of pulmonary emphysema caused an increase in sensitivity of the rat to toxicity from inhalation of propellants." | 1.25 | Toxicity of aerosol propellants in the respiratory and circulatory systems. VII. Influence of pulmonary emphysema and anesthesia in the rat. ( Aviado, DM; Watanabe, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sundin, LI | 1 |
| MacKenzie, I | 1 |
| Saville, VL | 1 |
| Waterfall, JF | 1 |
| Watanabe, T | 1 |
| Aviado, DM | 1 |
| Perry, SF | 1 |
| Thomas, S | 1 |
| Baskin, EP | 1 |
| Serik, CM | 1 |
| Wallace, AA | 1 |
| Brookes, LM | 1 |
| Selnick, HG | 1 |
| Claremon, DA | 1 |
| Lynch, JJ | 1 |
| Mian, R | 2 |
| Marshall, JM | 2 |
| Kumar, P | 1 |
| Cobbe, SM | 1 |
| Manley, BS | 1 |
| Alexopoulos, D | 1 |
8 other studies available for sotalol and Hypoxia
| Article | Year |
|---|---|
Responses of the branchial circulation to hypoxia in the Atlantic cod, Gadus morhua.
Topics: Animals; Blood Circulation; Blood Pressure; Cardiac Output; Epinephrine; Female; Fishes; Gills; Hypo | 1995 |
Differential class III and glibenclamide effects on action potential duration in guinea-pig papillary muscle during normoxia and hypoxia/ischaemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrophysiology; Glyburide; Guinea Pigs; Heart | 1993 |
Toxicity of aerosol propellants in the respiratory and circulatory systems. VII. Influence of pulmonary emphysema and anesthesia in the rat.
Topics: Adrenergic beta-Antagonists; Aerosol Propellants; Aerosols; Anesthesia; Animals; Arrhythmias, Cardia | 1975 |
The effects of endogenous or exogenous catecholamines on blood respiratory status during acute hypoxia in rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Carrier Proteins; Catecholamines; Epineph | 1991 |
Effects of new and potent methanesulfonanilide class III antiarrhythmic agents on myocardial refractoriness and contractility in isolated cardiac muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Ferrets; Heart; Hypo | 1991 |
The roles of catecholamines in responses evoked in arterioles and venules of rat skeletal muscle by systemic hypoxia.
Topics: Animals; Drug Synergism; Hypoxia; Male; Muscles; Norepinephrine; Phentolamine; Rats; Rats, Inbred St | 1991 |
Interactions between K+ and beta 2-adrenoreceptors in determining muscle vasodilatation induced in the rat by systemic hypoxia.
Topics: Animals; Blood Gas Analysis; Brachial Artery; Femoral Artery; Hypoxia; Muscles; Oxygen; Potassium; R | 1990 |
Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol.
Topics: Acidosis; Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Cultu | 1985 |