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sotalol and Hyperthyroidism

sotalol has been researched along with Hyperthyroidism in 10 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.

Research Excerpts

ExcerptRelevanceReference
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."9.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
"Serum T4, T3, rT3 and T3 resin uptake (T3 RU) were measured before and after 7 days of treatment with either propranolol, alprenolol, sotalol, atenolol or metoprolol in hyperthyroid patients."7.66Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism. ( Christensen, LK; Hansen, JM; Perrild, H; Skovsted, L, 1983)
"Ten hyperthyroid patients were studied before and after 2 weeks' beta-adrenoceptor blockade with sotalol."7.66Sotalol in hyperthyroidism. ( Kaur, S; Krassas, G; Ramsay, I, 1981)
" As the effects of beta-blocking agents on the symptoms of hyperthyroidism are correlated with the serum concentration of the drugs, sotalol, with its long half-life and unaltered elimination in hyperthyroidism, has certain advantages over propranolol in the treatment of thyrotoxicosis."6.65Pharmacokinetics of propranolol and sotalol in hyperthyroidism. ( Anttila, M; Aro, A; Korhonen, T; Sundquist, H, 1982)
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."5.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
" Because sympathetic activity is greatly enhanced with hyperthyroidism, we studied the effects of isoproterenol and the beta-blocker sotalol on cardiac contractility."3.68Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations. ( Grupp, G; Grupp, IL; Hewett, TE; Robbins, J; Subramaniam, A, 1993)
"Serum T4, T3, rT3 and T3 resin uptake (T3 RU) were measured before and after 7 days of treatment with either propranolol, alprenolol, sotalol, atenolol or metoprolol in hyperthyroid patients."3.66Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism. ( Christensen, LK; Hansen, JM; Perrild, H; Skovsted, L, 1983)
"Ten hyperthyroid patients were studied before and after 2 weeks' beta-adrenoceptor blockade with sotalol."3.66Sotalol in hyperthyroidism. ( Kaur, S; Krassas, G; Ramsay, I, 1981)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batcher, EL1
Tang, XC1
Singh, BN1
Singh, SN1
Reda, DJ1
Hershman, JM1
Perrild, H1
Hansen, JM1
Skovsted, L1
Christensen, LK1
Aro, A1
Anttila, M1
Korhonen, T1
Sundquist, H1
Kaur, S1
Krassas, G1
Ramsay, I2
Grupp, IL1
Subramaniam, A1
Hewett, TE1
Robbins, J1
Grupp, G1
Michel, JP1
Bonnetblanc, JM1
Catanzano, G1
Gualde, N1
Loubet, A1
Leboutet, MJ1
Liozon, F1
Wahlberg, P2
Carlsson, SA1
Wennström, J1
Ekelund, P1
Turner, P1

Reviews

1 review available for sotalol and Hyperthyroidism

ArticleYear
Beta-adrenergic receptor blocking drugs in hyperthyroidism.
    Drugs, 1974, Volume: 7, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Antithyroid Agents; Ethanolamines; Humans; Hyperthyroidism;

1974

Trials

3 trials available for sotalol and Hyperthyroidism

ArticleYear
Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation.
    The American journal of medicine, 2007, Volume: 120, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Female; Humans; Hyper

2007
Pharmacokinetics of propranolol and sotalol in hyperthyroidism.
    European journal of clinical pharmacology, 1982, Volume: 21, Issue:5

    Topics: Adult; Aged; Biological Availability; Female; Humans; Hyperthyroidism; Kinetics; Male; Middle Aged;

1982
Control of thyrotoxicosis with sotalol.
    Annals of clinical research, 1976, Volume: 8, Issue:6

    Topics: Clinical Trials as Topic; Drug Evaluation; Heart Rate; Humans; Hyperthyroidism; Sotalol

1976

Other Studies

6 other studies available for sotalol and Hyperthyroidism

ArticleYear
Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism.
    Clinical endocrinology, 1983, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Humans; Hyperthyroidism; Metoprolol;

1983
Sotalol in hyperthyroidism.
    Clinical endocrinology, 1981, Volume: 15, Issue:6

    Topics: Adult; Blood Pressure; Body Weight; Female; Humans; Hyperthyroidism; Male; Middle Aged; Pulse; Sotal

1981
Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Female; Heart; Hyperthyroidi

1993
Adrenergic beta-receptor blockade in hyperthyroidism.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:5

    Topics: Adrenergic beta-Antagonists; Humans; Hyperthyroidism; Propranolol; Sotalol

1975
Cutaneous thickening in hyperthyroidism treated with radioactive iodine and sotalol.
    Lancet (London, England), 1979, Jan-06, Volume: 1, Issue:8106

    Topics: Female; Humans; Hyperthyroidism; Iodine Radioisotopes; Male; Middle Aged; Scleroderma, Localized; So

1979
Long-term control of thyrotoxicosis with the beta-blocker sotalol--a model of untreated hyperthyroidism?
    Acta endocrinologica, 1978, Volume: 87, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hyperthyroidism; Male; Middle Aged; Sotalol; Thyrotrop

1978