sotalol has been researched along with Genetic Predisposition in 4 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a 53-year-old man with recurrent syncopal events and a malignant family history who was treated for 13 years with sotalol drug therapy with no further occurrence of Brugada syndrome symptoms." | 7.72 | Effectiveness of sotalol treatment in symptomatic Brugada syndrome. ( Chen, S; Chiamvimonvat, N; Glatter, KA; Keating, M; Scheinman, MM; Wang, Q, 2004) |
| "We describe a 53-year-old man with recurrent syncopal events and a malignant family history who was treated for 13 years with sotalol drug therapy with no further occurrence of Brugada syndrome symptoms." | 3.72 | Effectiveness of sotalol treatment in symptomatic Brugada syndrome. ( Chen, S; Chiamvimonvat, N; Glatter, KA; Keating, M; Scheinman, MM; Wang, Q, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romero, L | 1 |
| Trenor, B | 1 |
| Yang, PC | 1 |
| Saiz, J | 1 |
| Clancy, CE | 1 |
| Glatter, KA | 1 |
| Wang, Q | 1 |
| Keating, M | 1 |
| Chen, S | 1 |
| Chiamvimonvat, N | 1 |
| Scheinman, MM | 1 |
| Lehtonen, A | 1 |
| Fodstad, H | 1 |
| Laitinen-Forsblom, P | 1 |
| Toivonen, L | 1 |
| Kontula, K | 1 |
| Swan, H | 1 |
| Kaufman, ES | 1 |
1 review available for sotalol and Genetic Predisposition
| Article | Year |
|---|---|
Quinidine in short QT syndrome: an old drug for a new disease.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; | 2007 |
3 other studies available for sotalol and Genetic Predisposition
| Article | Year |
|---|---|
In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.
Topics: Action Potentials; Anti-Arrhythmia Agents; Astemizole; Cisapride; Computer Simulation; Gene Expressi | 2014 |
Effectiveness of sotalol treatment in symptomatic Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Diagnosis, Differential; Electrocardiography; Female; Genetic Predisp | 2004 |
Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; DNA Mutational Analysis; Electrocardiog | 2007 |