sotalol has been researched along with Extrasystole, Ventricular in 12 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias." | 9.14 | Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010) |
| "In the presence of sotalol, torsade de pointes reproducibly occurred in atrioventricular node-blocked hearts after lowering the potassium concentration to 1." | 5.31 | Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation. ( Breithardt, G; Eckardt, L; Haverkamp, W, 2002) |
| "To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias." | 5.14 | Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010) |
| "Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide." | 5.10 | Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002) |
| "To analyze action of digoxin and some non-digitalis drugs (beta-blockers, verapamil, amiodarone, d,l-sotalol) and their combinations on electrical activity of atria, frequency and structure of ventricular rhythm in patients with permanent atrial fibrillation." | 3.72 | [Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach]. ( Blagova, OV; Bogdanova, EA; Nedostup, AV; Platonova, AA, 2004) |
| "Sotalol's ability to suppress ventricular ectopy is similar to that of class I agents and better than that of standard beta-blockers." | 2.40 | Sotalol: An important new antiarrhythmic. ( Anderson, JL; Prystowsky, EN, 1999) |
| "Flecainide was the most effective AAD in the achievement of complete/near complete or significant PVC burden reduction, compared to propafenone and sotalol." | 1.91 | Idiopathic premature ventricular complexes treatment: Comparison of flecainide, propafenone, and sotalol. ( Bukumirić, Z; Jurčević, R; Kojić, D; Marić, M; Radunović, A; Rajsic, S; Sušić, M; Tomović, M; Žugić, V, 2023) |
| " A medication episode was defined as a timeframe in which the highest dosage at a fixed level of a single drug was used in a patient." | 1.62 | The Efficacy of Anti-Arrhythmic Drugs in Children With Idiopathic Frequent Symptomatic or Asymptomatic Premature Ventricular Complexes With or Without Asymptomatic Ventricular Tachycardia: a Retrospective Multi-Center Study. ( Bertels, RA; Blom, NA; Filippini, LH; Kammeraad, JAE; Knobbe, I; Kuipers, IM; Zeelenberg, AM, 2021) |
| "In the presence of sotalol, torsade de pointes reproducibly occurred in atrioventricular node-blocked hearts after lowering the potassium concentration to 1." | 1.31 | Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation. ( Breithardt, G; Eckardt, L; Haverkamp, W, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kojić, D | 1 |
| Radunović, A | 1 |
| Bukumirić, Z | 1 |
| Rajsic, S | 1 |
| Sušić, M | 1 |
| Marić, M | 1 |
| Žugić, V | 1 |
| Jurčević, R | 1 |
| Tomović, M | 1 |
| Bertels, RA | 1 |
| Kammeraad, JAE | 1 |
| Zeelenberg, AM | 1 |
| Filippini, LH | 1 |
| Knobbe, I | 1 |
| Kuipers, IM | 1 |
| Blom, NA | 1 |
| Sanders, RA | 1 |
| Kurosawa, TA | 1 |
| Venkataraman, G | 1 |
| Strickberger, SA | 1 |
| Gelzer, AR | 1 |
| Kraus, MS | 1 |
| Rishniw, M | 1 |
| Hemsley, SA | 1 |
| Moïse, NS | 2 |
| Makarov, LM | 1 |
| Komoliatova, VN | 1 |
| Meurs, KM | 1 |
| Spier, AW | 1 |
| Wright, NA | 1 |
| Atkins, CE | 1 |
| DeFrancesco, TC | 1 |
| Gordon, SG | 1 |
| Hamlin, RL | 1 |
| Keene, BW | 1 |
| Miller, MW | 1 |
| Nedostup, AV | 1 |
| Blagova, OV | 1 |
| Bogdanova, EA | 1 |
| Platonova, AA | 1 |
| Biagetti, MO | 1 |
| Arini, PD | 1 |
| Valverde, ER | 1 |
| Bretran, GC | 1 |
| Quinteiro, RA | 1 |
| Anderson, JL | 1 |
| Prystowsky, EN | 1 |
| Dionisio, P | 1 |
| Stroobandt, R | 1 |
| Vandenbulcke, F | 1 |
| Sinnaeve, A | 1 |
| Eckardt, L | 1 |
| Breithardt, G | 1 |
| Haverkamp, W | 1 |
1 review available for sotalol and Extrasystole, Ventricular
| Article | Year |
|---|---|
Sotalol: An important new antiarrhythmic.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Defibri | 1999 |
2 trials available for sotalol and Extrasystole, Ventricular
| Article | Year |
|---|---|
Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dog Diseases; Dogs; Drug | 2010 |
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C | 2002 |
9 other studies available for sotalol and Extrasystole, Ventricular
| Article | Year |
|---|---|
Idiopathic premature ventricular complexes treatment: Comparison of flecainide, propafenone, and sotalol.
Topics: Anti-Arrhythmia Agents; Electrocardiography; Flecainide; Humans; Propafenone; Retrospective Studies; | 2023 |
The Efficacy of Anti-Arrhythmic Drugs in Children With Idiopathic Frequent Symptomatic or Asymptomatic Premature Ventricular Complexes With or Without Asymptomatic Ventricular Tachycardia: a Retrospective Multi-Center Study.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Child; Child, Preschool; Female; Fl | 2021 |
ECG of the month. Ventricular arrhythmia in a dog.
Topics: Animals; Anti-Arrhythmia Agents; Dog Diseases; Dogs; Electrocardiography; Fatal Outcome; Female; Mex | 2013 |
Atrial fibrillation degenerates into ventricular fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Defibrillators, Impla | 2010 |
[Appearance of ECG signs of the Brugada syndrome during therapy with class 1C antiarrhythmic drug ethacizine].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Brugada Syndrome; Drug Substitution; Electrocardiograp | 2011 |
[Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Electrocardi | 2004 |
Role of dipolar and nondipolar components of the T wave in determining the T wave residuum in an isolated rabbit heart model.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Electric Stimu | 2004 |
Rate adaptive dual chamber pacing: inappropriate rate response due to pseudomalfunction of the QT biosensor.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Bradycardia; Cardiac Pacing, | 1999 |
Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Electrocardiography; El | 2002 |