sotalol has been researched along with Edema, Fetal in 10 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the case of atrial flutters the pregnant woman is treated with sotalol administered orally and, if no sinus rhythm is obtained nor a reduced ventricular rhythm occurs, subsequently with digoxin." | 4.81 | [Protocols for the treatment of supraventricular tachycardias in the fetus]. ( Ambachtsheer, EB; Meijboom, EJ; Oudijk, MA; Stoutenbeek, P, 2001) |
| "Fetal hydrops was seen in 20 patients; 17 received maternal therapy, 2 were delivered and 1 was not treated because it had a severe nontreatable cardiac malformation." | 2.69 | Atrial flutter in the perinatal age group: diagnosis, management and outcome. ( Benatar, AA; Brenner, JI; Kleinman, CS; Lisowski, LA; Meijboom, EJ; Soyeur, DJ; Stoutenbeek, P; Verheijen, PM, 2000) |
| "Fetal arrhythmias are common, and they may resolve spontaneously in majority of the cases." | 1.56 | Fetal arrhythmias: diagnosis and treatment. ( Yuan, SM, 2020) |
| "Fetal hydrops was present in six patients (five with SVT, one with AF)." | 1.39 | Sotalol as first-line treatment for fetal tachycardia and neonatal follow-up. ( Freund, MW; Manten, GT; Oudijk, MA; Pistorius, L; ter Heide, H; van der Heijden, LB, 2013) |
| "Digoxin therapy was initiated and sotalol was later added for new-onset hydrops." | 1.35 | Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? A case report. ( Gonzalez, JM; Merriman, JB; Rychik, J; Ural, SH, 2008) |
| " The mortality rate in this study was 19% (4 of 21 fetuses; 3 had SVT and 1 had AF); 3 deaths occurred just days after the initiation of sotalol therapy, and 1 occurred after a dosage increase." | 1.31 | Sotalol in the treatment of fetal dysrhythmias. ( Kapusta, L; Kleinman, CS; Meijboom, EJ; Michon, MM; Oudijk, MA; Stoutenbeek, P; Visser, GH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Refaat, M | 1 |
| El Dick, J | 1 |
| Sabra, M | 1 |
| Bitar, F | 1 |
| Tayeh, C | 1 |
| Abutaqa, M | 1 |
| Arabi, M | 1 |
| Yuan, SM | 1 |
| Merriman, JB | 1 |
| Gonzalez, JM | 1 |
| Rychik, J | 1 |
| Ural, SH | 1 |
| Suri, V | 1 |
| Keepanaseril, A | 1 |
| Aggarwal, N | 1 |
| Vijayvergiya, R | 1 |
| Shah, A | 1 |
| Moon-Grady, A | 1 |
| Bhogal, N | 1 |
| Collins, KK | 1 |
| Tacy, T | 1 |
| Brook, M | 1 |
| Hornberger, LK | 1 |
| van der Heijden, LB | 1 |
| Oudijk, MA | 3 |
| Manten, GT | 1 |
| ter Heide, H | 1 |
| Pistorius, L | 1 |
| Freund, MW | 1 |
| Jouannic, JM | 1 |
| Delahaye, S | 1 |
| Le Bidois, J | 1 |
| Fermont, L | 1 |
| Villain, E | 1 |
| Dommergues, M | 1 |
| Dumez, Y | 1 |
| Lisowski, LA | 1 |
| Verheijen, PM | 1 |
| Benatar, AA | 1 |
| Soyeur, DJ | 1 |
| Stoutenbeek, P | 3 |
| Brenner, JI | 1 |
| Kleinman, CS | 2 |
| Meijboom, EJ | 3 |
| Michon, MM | 1 |
| Kapusta, L | 1 |
| Visser, GH | 1 |
| Ambachtsheer, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety Assessment for Sotalol Protocol in Outpatient Unit[NCT05418036] | Phase 4 | 110 participants (Anticipated) | Interventional | 2020-10-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for sotalol and Edema, Fetal
| Article | Year |
|---|---|
Sotalol as an effective adjunct therapy in the management of supraventricular tachycardia induced fetal hydrops fetalis.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Female; Fetal Diseases; Flecainid | 2020 |
Prenatal management with digoxin and sotalol combination for fetal supraventricular tachycardia: case report and review of literature.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Female; Humans; Hydrops Fetalis; | 2009 |
[Protocols for the treatment of supraventricular tachycardias in the fetus].
Topics: Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Drug Therapy, Combination; Fema | 2001 |
1 trial available for sotalol and Edema, Fetal
| Article | Year |
|---|---|
Atrial flutter in the perinatal age group: diagnosis, management and outcome.
Topics: Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Echocardiography, Doppler; Electric Countershock; E | 2000 |
6 other studies available for sotalol and Edema, Fetal
| Article | Year |
|---|---|
Fetal arrhythmias: diagnosis and treatment.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digoxin; Female; Humans; Hydrops Fetalis; Pregnancy; S | 2020 |
Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? A case report.
Topics: Adolescent; Anti-Arrhythmia Agents; Digoxin; Female; Fetal Therapies; Humans; Hydrops Fetalis; Pregn | 2008 |
Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias.
Topics: Abortion, Induced; Anti-Arrhythmia Agents; Atrial Flutter; Bradycardia; Catheter Ablation; Digoxin; | 2012 |
Sotalol as first-line treatment for fetal tachycardia and neonatal follow-up.
Topics: Anti-Arrhythmia Agents; Atrial Flutter; Echocardiography; Female; Fetal Diseases; Follow-Up Studies; | 2013 |
[Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Echocardiography; F | 2003 |
Sotalol in the treatment of fetal dysrhythmias.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Hydrops Fetalis; Inf | 2000 |