sotalol has been researched along with Drug Overdose in 7 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Torsade de pointes is a well-established toxic effect of sotalol hydrochloride." | 7.69 | Torsade de pointes and prolonged QT interval from surreptitious use of sotalol: use of drug levels in diagnosis. ( Estes, NA; Foote, CB; Homoud, MK; Link, MS; Sloan, SB; Wang, PJ, 1997) |
| " We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse." | 7.69 | Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997) |
| "Torsade de pointes is a polymorphic ventricular tachyarrhythmia associated with a long QT interval." | 6.40 | Torsade de pointes with sotalol overdose treated successfully with lidocaine. ( Assimes, TL; Malcolm, I, 1998) |
| "Torsade de pointes is a well-established toxic effect of sotalol hydrochloride." | 3.69 | Torsade de pointes and prolonged QT interval from surreptitious use of sotalol: use of drug levels in diagnosis. ( Estes, NA; Foote, CB; Homoud, MK; Link, MS; Sloan, SB; Wang, PJ, 1997) |
| " We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse." | 3.69 | Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997) |
| "Torsade de pointes is a polymorphic ventricular tachyarrhythmia associated with a long QT interval." | 2.40 | Torsade de pointes with sotalol overdose treated successfully with lidocaine. ( Assimes, TL; Malcolm, I, 1998) |
| "Sotalol is a beta-blocker with additional class III activity." | 2.38 | Class III antiarrhythmics in overdose. Presenting features and management principles. ( Holt, DW; Leatham, EW; McKenna, WJ, 1993) |
| "Propranolol was the only beta blocker associated with seizure; of those who ingested more than 2 g of propranolol, two thirds had a seizure." | 1.29 | Relative toxicity of beta blockers in overdose. ( Buckley, NA; Dawson, AH; Epid, D; Reith, DM; Sayer, GP; Whyte, IM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lauterbach, M | 1 |
| Lip, GY | 1 |
| Ferner, RE | 1 |
| Leatham, EW | 1 |
| Holt, DW | 1 |
| McKenna, WJ | 1 |
| Reith, DM | 1 |
| Dawson, AH | 1 |
| Epid, D | 1 |
| Whyte, IM | 1 |
| Buckley, NA | 1 |
| Sayer, GP | 1 |
| Link, MS | 1 |
| Foote, CB | 1 |
| Sloan, SB | 1 |
| Homoud, MK | 1 |
| Wang, PJ | 1 |
| Estes, NA | 1 |
| Sandeman, DJ | 1 |
| Alahakoon, TI | 1 |
| Bentley, SC | 1 |
| Assimes, TL | 1 |
| Malcolm, I | 1 |
3 reviews available for sotalol and Drug Overdose
| Article | Year |
|---|---|
Poisoning with anti-hypertensive drugs: beta-adrenoceptor blocker drugs.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cardiovascular System; Central Nervous System; | 1995 |
Class III antiarrhythmics in overdose. Presenting features and management principles.
Topics: Amiodarone; Anti-Arrhythmia Agents; Biological Availability; Bretylium Compounds; Drug Overdose; Hum | 1993 |
Torsade de pointes with sotalol overdose treated successfully with lidocaine.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Follo | 1998 |
4 other studies available for sotalol and Drug Overdose
| Article | Year |
|---|---|
Response to Neuvonen et al: Sotalol, unlike the other beta-blockers, increases the QT
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Drug Overdose; Humans; Sotalol; Torsades | 2019 |
Relative toxicity of beta blockers in overdose.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child, Preschool; Databases, Factual | 1996 |
Torsade de pointes and prolonged QT interval from surreptitious use of sotalol: use of drug levels in diagnosis.
Topics: Adult; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Female; Humans; Long QT Syndrome; | 1997 |
Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine.
Topics: Adrenergic Agonists; Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Critical Care; | 1997 |