sotalol has been researched along with Delayed Effects, Prenatal Exposure in 2 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increased motor activity and poor performance in the active avoidance test were observed in the offspring of rats treated with dl-propranolol or sotalol during pregnancy, but not with atenolol and d-propranolol." | 3.68 | Behavioral and biochemical studies in rats following prenatal treatment with beta-adrenoceptor antagonists. ( Gitter, S; Gordon, I; Rehavi, M; Speiser, Z, 1991) |
| " Investigators have hoped that these drugs would be as effective as sotalol and amiodarone but have fewer adverse effects." | 2.40 | The side effect profile of class III antiarrhythmic drugs: focus on d,l-sotalol. ( MacNeil, DJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MacNeil, DJ | 1 |
| Speiser, Z | 1 |
| Gordon, I | 1 |
| Rehavi, M | 1 |
| Gitter, S | 1 |
1 review available for sotalol and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
The side effect profile of class III antiarrhythmic drugs: focus on d,l-sotalol.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Conduction System; Heart Failur | 1997 |
1 other study available for sotalol and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Behavioral and biochemical studies in rats following prenatal treatment with beta-adrenoceptor antagonists.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atenolol; Avoidance Le | 1991 |