sotalol has been researched along with Death, Sudden in 8 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This open, parallel-group study compares quinidine and sotalol treatment for maintenance of sinus rhythm after direct current conversion of patients with chronic atrial fibrillation." | 9.06 | Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation. ( Edvardsson, N; Juul-Möller, S; Rehnqvist-Ahlberg, N, 1990) |
| "This open, parallel-group study compares quinidine and sotalol treatment for maintenance of sinus rhythm after direct current conversion of patients with chronic atrial fibrillation." | 5.06 | Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation. ( Edvardsson, N; Juul-Möller, S; Rehnqvist-Ahlberg, N, 1990) |
| "Recently completed Beta-Blocker Heart Attack Trial in which propranolol was administered to patients following an acute myocardial infarction resulted in a 26% decrease in total mortality and a 23% decrease in total coronary events in the propranolol-treated patients as compared to the placebo patients during the average follow-up of 25 months." | 5.05 | The Beta-Blocker Heart Attack Trial in perspective. ( Goldstein, S, 1983) |
| "Ventricular arrhythmias play an important role in the pathophysiologic aspects of sudden cardiac death." | 1.27 | Identification of patients at high risk for sudden cardiac death. ( Bigger, JT, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conte, G | 1 |
| Sieira, J | 1 |
| Ciconte, G | 1 |
| de Asmundis, C | 1 |
| Chierchia, GB | 1 |
| Baltogiannis, G | 1 |
| Di Giovanni, G | 1 |
| La Meir, M | 1 |
| Wellens, F | 1 |
| Czapla, J | 1 |
| Wauters, K | 1 |
| Levinstein, M | 1 |
| Saitoh, Y | 1 |
| Irfan, G | 1 |
| Julià, J | 1 |
| Pappaert, G | 1 |
| Brugada, P | 2 |
| Goldstein, S | 1 |
| Bigger, JT | 1 |
| Feld, GK | 1 |
| Juul-Möller, S | 1 |
| Edvardsson, N | 1 |
| Rehnqvist-Ahlberg, N | 1 |
| Roden, DM | 1 |
| Woosley, RL | 1 |
| Lemery, R | 1 |
| Havenith, M | 1 |
| Barbour, D | 1 |
| Roberts, WC | 1 |
| Wellens, HJ | 1 |
| Lynch, JJ | 1 |
| Coskey, LA | 1 |
| Montgomery, DG | 1 |
| Lucchesi, BR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000492] | Phase 3 | 0 participants | Interventional | 1977-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sotalol and Death, Sudden
| Article | Year |
|---|---|
Atrial fibrillation. Is there a safe and highly effective pharmacological treatment?
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Death, Sudden; Electric Count | 1990 |
2 trials available for sotalol and Death, Sudden
| Article | Year |
|---|---|
The Beta-Blocker Heart Attack Trial in perspective.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sud | 1983 |
Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Death, Sudden; Dose-Response Rel | 1990 |
5 other studies available for sotalol and Death, Sudden
| Article | Year |
|---|---|
Implantable cardioverter-defibrillator therapy in Brugada syndrome: a 20-year single-center experience.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Belgium; Brugada Syndr | 2015 |
Identification of patients at high risk for sudden cardiac death.
Topics: Anilides; Arrhythmias, Cardiac; Death, Sudden; Encainide; Heart; Heart Ventricles; Humans; Prognosis | 1984 |
QT prolongation and arrhythmia suppression.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Deafness; Death, Sudden; Elect | 1985 |
Sudden death in hemochromatosis after closed-chest catheter ablation of the atrioventricular junction.
Topics: Atrial Fibrillation; Atrioventricular Node; Death, Sudden; Electric Countershock; Electrocardiograph | 1988 |
Prevention of ventricular fibrillation by dextrorotatory sotalol in a conscious canine model of sudden coronary death.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Coronary Disease; Death, Sudden; Diseas | 1985 |