sotalol has been researched along with Constriction, Pathological in 3 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subaortic stenosis (SAS) is a commonly diagnosed canine congenital cardiac defect, with severe forms of carrying a poor long-term prognosis." | 3.11 | Echocardiographic and electrocardiographic effects of atenolol versus sotalol in dogs with severe subaortic stenosis. ( LeBlanc, NL; Owens, EJ; Scollan, KF; Treseder, J, 2022) |
| "Dogs with severe subaortic stenosis (SAS) are at risk of dying suddenly from fatal arrhythmias." | 1.91 | Association of sotalol versus atenolol therapy with survival in dogs with severe subaortic stenosis. ( Obernberger, C; Shear, M; Showers, A; Tjostheim, SS, 2023) |
| "Resistance across the stenosis decreased significantly (p less than 0." | 1.26 | Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart. ( Buck, JD; Gross, GJ; Hardman, HF; Warltier, DC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Owens, EJ | 1 |
| LeBlanc, NL | 1 |
| Treseder, J | 1 |
| Scollan, KF | 1 |
| Tjostheim, SS | 1 |
| Showers, A | 1 |
| Obernberger, C | 1 |
| Shear, M | 1 |
| Buck, JD | 1 |
| Hardman, HF | 1 |
| Warltier, DC | 1 |
| Gross, GJ | 1 |
1 trial available for sotalol and Constriction, Pathological
| Article | Year |
|---|---|
Echocardiographic and electrocardiographic effects of atenolol versus sotalol in dogs with severe subaortic stenosis.
Topics: Animals; Anti-Arrhythmia Agents; Aortic Stenosis, Subvalvular; Atenolol; Constriction, Pathologic; C | 2022 |
2 other studies available for sotalol and Constriction, Pathological
| Article | Year |
|---|---|
Association of sotalol versus atenolol therapy with survival in dogs with severe subaortic stenosis.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Aortic Stenosis, Subvalvular; Atenolol | 2023 |
Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation | 1981 |