sotalol has been researched along with Cardiovascular Diseases in 7 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sotalol is a beta-adrenoceptor blocking agent devoid of intrinsic sympathomimetic activity, membrane stabilising actions and cardioselectivity." | 3.76 | Sotalol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use. ( Deedwania, P; Nademanee, K; Singh, BN; Sorkin, EM; Ward, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, KY | 1 |
| Tseng, PT | 1 |
| Wu, YC | 1 |
| Tu, YK | 1 |
| Stubbs, B | 1 |
| Su, KP | 1 |
| Matsuoka, YJ | 1 |
| Hsu, CW | 1 |
| Lin, CH | 1 |
| Chen, YW | 1 |
| Lin, PY | 1 |
| Murin, J | 1 |
| Naditch-Brûlé, L | 1 |
| Brette, S | 1 |
| Chiang, CE | 1 |
| O'Neill, J | 1 |
| Steg, PG | 1 |
| Pappone, C | 1 |
| Augello, G | 1 |
| Sala, S | 1 |
| Gugliotta, F | 1 |
| Vicedomini, G | 1 |
| Gulletta, S | 1 |
| Paglino, G | 1 |
| Mazzone, P | 1 |
| Sora, N | 1 |
| Greiss, I | 1 |
| Santagostino, A | 1 |
| LiVolsi, L | 1 |
| Pappone, N | 1 |
| Radinovic, A | 1 |
| Manguso, F | 1 |
| Santinelli, V | 1 |
| Poisson, D | 1 |
| Pariat, C | 1 |
| Lefebvre, MA | 1 |
| Potocki, B | 1 |
| Courtois, P | 1 |
| Meyer, C | 1 |
| Singh, BN | 2 |
| Deedwania, P | 1 |
| Nademanee, K | 1 |
| Ward, A | 1 |
| Sorkin, EM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Treating Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF2) Trial[NCT00340314] | Phase 4 | 198 participants | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sotalol and Cardiovascular Diseases
| Article | Year |
|---|---|
Do beta-adrenergic blocking agents increase asthma exacerbation? A network meta-analysis of randomized controlled trials.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Cardiovascular Diseases; Ce | 2021 |
Sotalol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.
Topics: Adult; Aged; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Female; Humans; Pregnancy; | 1987 |
2 trials available for sotalol and Cardiovascular Diseases
| Article | Year |
|---|---|
A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.
Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Diseases; | 2006 |
Sotalol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.
Topics: Adult; Aged; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Female; Humans; Pregnancy; | 1987 |
4 other studies available for sotalol and Cardiovascular Diseases
| Article | Year |
|---|---|
Clinical characteristics, management, and control of permanent vs. nonpermanent atrial fibrillation: insights from the RealiseAF survey.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Dis | 2014 |
[Cardiovascular effects of hypothalamic stimulations in anesthetized dogs: changes under the action of sotalol].
Topics: Anesthetics; Animals; Cardiovascular Diseases; Dogs; Electric Stimulation; Hypothalamus; Sotalol | 1984 |
New drugs in the cardiovascular arena.
Topics: Amlodipine; Bisoprolol; Cardiovascular Agents; Cardiovascular Diseases; Humans; Quinolines; Sotalol; | 1993 |
CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiovascular Diseases; Clinical Trials as Top | 2001 |