Page last updated: 2024-11-04

sotalol and Cardiomyopathies

sotalol has been researched along with Cardiomyopathies in 13 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"We explored the central hemodynamic responses to oral sotalol during dose titration in patients with ventricular arrhythmias who underwent programmed ventricular stimulation."7.68Effect of oral sotalol on systemic hemodynamics and programmed electrical stimulation in patients with ventricular arrhythmias and structural heart disease. ( Deitchman, D; Gomes, JA; Kukin, M; Pe, E; Stewart, D; Winters, SL, 1993)
"Sotalol is a non-selective beta-adrenergic blocking agent with class III antiarrhythmic properties."5.27The effect of sotalol on exercise-induced ventricular arrhythmias. ( Glogar, D; Petzl, DH; Probst, P; Schuster, E, 1988)
"A case is described of cardiogenic shock that occurred following use of sotalol in a patient with severe left ventricular dysfunction."3.81Left Ventricular Assist Device (LVAD) as a Bridge to Recovery for Tachycardia-Mediated Cardiomyopathy. ( Bergin, P; Kaye, DM; Mariani, JA; McGiffin, DC; Saxena, P; Stokes, MB, 2015)
"We explored the central hemodynamic responses to oral sotalol during dose titration in patients with ventricular arrhythmias who underwent programmed ventricular stimulation."3.68Effect of oral sotalol on systemic hemodynamics and programmed electrical stimulation in patients with ventricular arrhythmias and structural heart disease. ( Deitchman, D; Gomes, JA; Kukin, M; Pe, E; Stewart, D; Winters, SL, 1993)
" At each dosing extreme, on-drug JTc was significantly longer in women (p < or =0."2.69JTc prolongation with d,l-sotalol in women versus men. ( Archibald, D; Hardy, S; Lehmann, MH; MacNeil, DJ, 1999)
"Sotalol is a non-selective beta-adrenergic blocking agent with class III antiarrhythmic properties."1.27The effect of sotalol on exercise-induced ventricular arrhythmias. ( Glogar, D; Petzl, DH; Probst, P; Schuster, E, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sarangi, PK1
Joseph, E1
Irodi, A1
Chacko, BR1
Chase, D1
Ge, H2
Li, X2
Zhang, Y1
Liu, H2
Jiang, H2
Stokes, MB1
Saxena, P1
Mariani, JA1
Kaye, DM1
Bergin, P1
McGiffin, DC1
Winter, RL1
Hariu, CD1
Saunders, AB1
Furushima, H1
Chinushi, M2
Okamura, K1
Komura, S1
Tanabe, Y1
Sato, A1
Izumi, D1
Aizawa, Y2
Winters, SL1
Kukin, M1
Pe, E1
Stewart, D1
Deitchman, D1
Gomes, JA1
Montero, M1
Schmitt, C1
Lehmann, MH1
Hardy, S1
Archibald, D1
MacNeil, DJ1
Laurenzi, F1
Avella, A1
Adinolfi, E1
Dini, P1
Mezaki, T1
Aoki, Y1
Nakagawa, I1
Washizuka, T1
Hackett, LP1
Wojnar-Horton, RE1
Dusci, LJ1
Ilett, KF1
Roberts, MJ1
Petzl, DH1
Probst, P1
Glogar, D1
Schuster, E1

Trials

2 trials available for sotalol and Cardiomyopathies

ArticleYear
Effect of dl-sotalol on mortality and recurrence of ventricular tachyarrhythmias: ischemic compared to nonischemic cardiomyopathy.
    Pacing and clinical electrophysiology : PACE, 2007, Volume: 30, Issue:9

    Topics: Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Comorbidity; Female; Humans; Incidence; Japan; Male;

2007
JTc prolongation with d,l-sotalol in women versus men.
    The American journal of cardiology, 1999, Feb-01, Volume: 83, Issue:3

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiomyopathies; Electrocardiography; Female; Humans;

1999

Other Studies

11 other studies available for sotalol and Cardiomyopathies

ArticleYear
An unusual childhood cardiomyopathy.
    European heart journal. Cardiovascular Imaging, 2019, Aug-01, Volume: 20, Issue:8

    Topics: Adolescent; Anti-Arrhythmia Agents; Cardiomyopathies; Catheter Ablation; Contrast Media; Diagnosis,

2019
[Clinical course and treatment of ectopic atrial tachycardia in 144 children].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2015, Volume: 53, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Catheter Ablation; Child; Child, Preschool; Ec

2015
Left Ventricular Assist Device (LVAD) as a Bridge to Recovery for Tachycardia-Mediated Cardiomyopathy.
    Journal of cardiac surgery, 2015, Volume: 30, Issue:11

    Topics: Anti-Arrhythmia Agents; Cardiomyopathies; Heart Ventricles; Heart-Assist Devices; Humans; Male; Midd

2015
Predictors of Pharmacological Therapy of Ectopic Atrial Tachycardia in Children.
    Pediatric cardiology, 2017, Volume: 38, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Child; Child, Preschool; China; Drug Therapy,

2017
ECG of the month. Arrhythmogenic right ventricular cardiomyopathy in a Boxer.
    Journal of the American Veterinary Medical Association, 2010, May-01, Volume: 236, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzazepines; Cardiomyopathies; Cardiotoni

2010
Effect of oral sotalol on systemic hemodynamics and programmed electrical stimulation in patients with ventricular arrhythmias and structural heart disease.
    The American journal of cardiology, 1993, Aug-12, Volume: 72, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiac Pacing, Artifici

1993
Recording of transmembrane action potentials in chronic ischemic heart disease and dilated cardiomyopathy and the effects of the new class III antiarrhythmic agents D-sotalol and dofetilide.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:4

    Topics: Anti-Arrhythmia Agents; Cardiomyopathies; Coronary Disease; Heart; Heart Ventricles; Humans; In Vitr

1996
[Role of electrophysiology in the prognosis and therapy of cardiomyopathies].
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:10

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopath

1999
Demonstration of transient entrainment in monomorphic sustained ventricular tachycardia associated with cardiac sarcoidosis.
    Japanese circulation journal, 2000, Volume: 64, Issue:8

    Topics: Cardiomyopathies; Electric Stimulation Therapy; Electrocardiography; Humans; Male; Middle Aged; Pred

2000
Excretion of sotalol in breast milk.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Cardiomyopathies; Female; Humans; Infant, Newborn; Milk, Human; Pregnan

1990
The effect of sotalol on exercise-induced ventricular arrhythmias.
    European heart journal, 1988, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathies; Coronary Disease; D

1988