sotalol has been researched along with Cardiac Hypertrophy in 3 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of 6 months treatment with Sotalol on the blood pressure, left ventricular mass and function, were studied in patients with essential hypertension and left ventricular hypertrophy." | 4.78 | [Effect of sotalol on left ventricular mass and function in the hypertensive patient]. ( Dallocchio, M; Durandet, P; Gosse, P; Leherissier, A; Roudaut, R; Vrancea, F, 1991) |
| "The effects of changes in left ventricular mass following beta-adrenergic blockade therapy (sotalol) on left ventricular filling indices were examined in 16 patients with essential hypertension aged 46 +/- 8." | 3.67 | Effect of regression of left ventricular hypertrophy following sotalol therapy on diastolic function in hypertensive patients. ( Helmi, SM; Ibrahim, MM; Zaghloul, SS, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gosse, P | 1 |
| Durandet, P | 1 |
| Roudaut, R | 1 |
| Leherissier, A | 1 |
| Vrancea, F | 1 |
| Dallocchio, M | 1 |
| Ibrahim, MM | 1 |
| Zaghloul, SS | 1 |
| Helmi, SM | 1 |
| Fournier, C | 1 |
| Bourmayan, C | 1 |
| Cadillac, M | 1 |
| Dinanian, J | 1 |
| Blondeau, M | 1 |
| Gay, J | 1 |
1 review available for sotalol and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Effect of sotalol on left ventricular mass and function in the hypertensive patient].
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography, Doppler; Female; Heart Rate; Humans; Hy | 1991 |
1 trial available for sotalol and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Intermediate-term trial treatment of arrhythmia in hypertrophic myocardiopathy with sotalol].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiomegaly; Clinical Trials as T | 1988 |
1 other study available for sotalol and Cardiac Hypertrophy
| Article | Year |
|---|---|
Effect of regression of left ventricular hypertrophy following sotalol therapy on diastolic function in hypertensive patients.
Topics: Adult; Blood Pressure; Cardiomegaly; Diastole; Echocardiography; Female; Heart Rate; Humans; Hyperte | 1987 |