sotalol has been researched along with Canine Diseases in 10 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias." | 9.14 | Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010) |
| "To determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias." | 7.88 | Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. ( Bélanger, C; Gunther-Harrington, CT; Kaplan, JL; Mueller, MS; Nishimura, S; Oldach, MS; Stern, JA; Visser, LC, 2018) |
| "To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias." | 5.14 | Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010) |
| "Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide." | 5.10 | Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002) |
| "To determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias." | 3.88 | Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. ( Bélanger, C; Gunther-Harrington, CT; Kaplan, JL; Mueller, MS; Nishimura, S; Oldach, MS; Stern, JA; Visser, LC, 2018) |
| "Subaortic stenosis (SAS) is a commonly diagnosed canine congenital cardiac defect, with severe forms of carrying a poor long-term prognosis." | 3.11 | Echocardiographic and electrocardiographic effects of atenolol versus sotalol in dogs with severe subaortic stenosis. ( LeBlanc, NL; Owens, EJ; Scollan, KF; Treseder, J, 2022) |
| "Dogs with severe subaortic stenosis (SAS) are at risk of dying suddenly from fatal arrhythmias." | 1.91 | Association of sotalol versus atenolol therapy with survival in dogs with severe subaortic stenosis. ( Obernberger, C; Shear, M; Showers, A; Tjostheim, SS, 2023) |
| "Treatment with sotalol enhanced the "zone of avoidance"." | 1.36 | "Zone of avoidance": RR interval distribution in tachograms, histograms, and Poincaré plots of a Boxer dog. ( Gladuli, A; Hemsley, SA; Moïse, NS; Otani, NF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Owens, EJ | 1 |
| LeBlanc, NL | 1 |
| Treseder, J | 1 |
| Scollan, KF | 1 |
| Tjostheim, SS | 1 |
| Showers, A | 1 |
| Obernberger, C | 1 |
| Shear, M | 1 |
| Visser, LC | 1 |
| Kaplan, JL | 1 |
| Nishimura, S | 1 |
| Gunther-Harrington, CT | 1 |
| Bélanger, C | 1 |
| Oldach, MS | 1 |
| Stern, JA | 1 |
| Mueller, MS | 1 |
| Sanders, RA | 1 |
| Kurosawa, TA | 1 |
| Armentano, RA | 1 |
| Schmidt, MK | 1 |
| Maisenbacher, HW | 1 |
| Winter, RL | 1 |
| Hariu, CD | 1 |
| Saunders, AB | 1 |
| Gelzer, AR | 1 |
| Kraus, MS | 1 |
| Rishniw, M | 1 |
| Hemsley, SA | 2 |
| Moïse, NS | 4 |
| Gladuli, A | 1 |
| Otani, NF | 1 |
| Meurs, KM | 1 |
| Spier, AW | 1 |
| Wright, NA | 1 |
| Atkins, CE | 1 |
| DeFrancesco, TC | 1 |
| Gordon, SG | 1 |
| Hamlin, RL | 1 |
| Keene, BW | 1 |
| Miller, MW | 1 |
| Mérot, J | 1 |
| Probst, V | 1 |
| Debailleul, M | 1 |
| Gerlach, U | 1 |
| Le Marec, H | 1 |
| Charpentier, F | 1 |
3 trials available for sotalol and Canine Diseases
| Article | Year |
|---|---|
Echocardiographic and electrocardiographic effects of atenolol versus sotalol in dogs with severe subaortic stenosis.
Topics: Animals; Anti-Arrhythmia Agents; Aortic Stenosis, Subvalvular; Atenolol; Constriction, Pathologic; C | 2022 |
Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dog Diseases; Dogs; Drug | 2010 |
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C | 2002 |
7 other studies available for sotalol and Canine Diseases
| Article | Year |
|---|---|
Association of sotalol versus atenolol therapy with survival in dogs with severe subaortic stenosis.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Aortic Stenosis, Subvalvular; Atenolol | 2023 |
Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dog Diseases; Dogs; Echocardiography; Female; | 2018 |
ECG of the month. Ventricular arrhythmia in a dog.
Topics: Animals; Anti-Arrhythmia Agents; Dog Diseases; Dogs; Electrocardiography; Fatal Outcome; Female; Mex | 2013 |
ECG of the Month. Atrial flutter.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Dog Diseases; Dogs; Electrocardiography; Male; Sota | 2010 |
ECG of the month. Arrhythmogenic right ventricular cardiomyopathy in a Boxer.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzazepines; Cardiomyopathies; Cardiotoni | 2010 |
"Zone of avoidance": RR interval distribution in tachograms, histograms, and Poincaré plots of a Boxer dog.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Dog Diseases; Dogs; Electrocardiography, Ambulat | 2010 |
Electropharmacological characterization of cardiac repolarization in German shepherd dogs with an inherited syndrome of sudden death: abnormal response to potassium channel blockers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromans; Death, Sudden, Cardiac; Dog Disease | 2000 |