sotalol has been researched along with Bradycardia in 26 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of our study was to compare sotalol (S) versus beta-blocking agents (BB) in terms of prevention of ATA, cardioversions (CVs), and cardiovascular hospitalizations (H) in patients paced for bradycardia-tachycardia form of sinus node disease (BT-SND)." | 9.13 | The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker. ( Boriani, G; Botto, G; Capucci, A; Favale, S; Marotta, T; Molon, G; Porfilio, A; Proclemer, A; Spampinato, A; Vimercati, M, 2008) |
| "We sought to determine the yield of in-hospital monitoring for detection of significant arrhythmia complications in patients starting sotalol therapy for atrial arrhythmias and to identify factors that might predict safe outpatient initiation." | 7.70 | Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications. ( Chung, MK; Jaeger, FJ; Kidwell, GA; Miller, DP; Morant, VA; Niebauer, MJ; Pinski, SL; Schweikert, RA; Tchou, PJ; Trohman, RG; Wilkoff, BL, 1998) |
| "Glucagon is considered the drug of choice for treating bradycardia and hypotension encountered during beta-blocker poisoning." | 7.69 | Sotalol-induced bradycardia reversed by glucagon. ( Daya, MR; Fernandes, CM, 1995) |
| "The authors envisage the hypothesis of an embryofetal intoxication by a beta-blocker (B-), sotalol, taken by the mother, not hypertensive, during all her pregnancy (160 mg/day)." | 7.67 | [Possible embryofetopathy caused by beta-blocker (sotalol) taken throughout the pregnancy]. ( Babin, JP; Carre, M; Martin, C, 1985) |
| "Sotalol was initiated." | 6.73 | Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation. ( Butter, C; Gerhardt, L; Helms, S; Schlegl, M; Stockburger, M, 2007) |
| "Sotalol is a beta-adrenergic blocking drug with the additional property of lengthening the cardiac action potential." | 6.67 | Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery. ( Dion, R; Evenepoel, M; Evrard, P; Goenen, M; Jacquet, L; Marenne, F; Verhelst, R, 1994) |
| " Conversion to sinus rhythm was achieved in 16 out of 22 hemodynamically stable children with a dosage of 4." | 5.30 | Sotalol for atrial tachycardias after surgery for congenital heart disease. ( Beaufort-Krol, GC; Bink-Boelkens, MT, 1997) |
| " The aim of our study was to compare sotalol (S) versus beta-blocking agents (BB) in terms of prevention of ATA, cardioversions (CVs), and cardiovascular hospitalizations (H) in patients paced for bradycardia-tachycardia form of sinus node disease (BT-SND)." | 5.13 | The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker. ( Boriani, G; Botto, G; Capucci, A; Favale, S; Marotta, T; Molon, G; Porfilio, A; Proclemer, A; Spampinato, A; Vimercati, M, 2008) |
| " β blockers, alone or in combination with digoxin, or non-dihydropyridine calcium-channel blockers (not in heart failure) effectively lower the heart rate." | 4.93 | Rate control in atrial fibrillation. ( Crijns, HJ; Olshansky, B; Rienstra, M; Van Gelder, IC, 2016) |
| "Sotalol, a Vaughan-Williams Class III antiarrhythmic medication, is used to manage atrial arrhythmias." | 3.96 | Multicenter Analysis of Dosing Protocols for Sotalol Initiation. ( Biswas, M; Chung, M; Levy, A; Newton-Cheh, C; Noseworthy, PA; Rosenberg, MA; Tarakji, K; Weber, R, 2020) |
| "We sought to determine the yield of in-hospital monitoring for detection of significant arrhythmia complications in patients starting sotalol therapy for atrial arrhythmias and to identify factors that might predict safe outpatient initiation." | 3.70 | Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications. ( Chung, MK; Jaeger, FJ; Kidwell, GA; Miller, DP; Morant, VA; Niebauer, MJ; Pinski, SL; Schweikert, RA; Tchou, PJ; Trohman, RG; Wilkoff, BL, 1998) |
| "Glucagon is considered the drug of choice for treating bradycardia and hypotension encountered during beta-blocker poisoning." | 3.69 | Sotalol-induced bradycardia reversed by glucagon. ( Daya, MR; Fernandes, CM, 1995) |
| "The authors envisage the hypothesis of an embryofetal intoxication by a beta-blocker (B-), sotalol, taken by the mother, not hypertensive, during all her pregnancy (160 mg/day)." | 3.67 | [Possible embryofetopathy caused by beta-blocker (sotalol) taken throughout the pregnancy]. ( Babin, JP; Carre, M; Martin, C, 1985) |
| "Sotalol was initiated." | 2.73 | Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation. ( Butter, C; Gerhardt, L; Helms, S; Schlegl, M; Stockburger, M, 2007) |
| "Sotalol is a beta-adrenergic blocking drug with the additional property of lengthening the cardiac action potential." | 2.67 | Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery. ( Dion, R; Evenepoel, M; Evrard, P; Goenen, M; Jacquet, L; Marenne, F; Verhelst, R, 1994) |
| "Drugs can cause cardiac arrhythmias in a number of clinical situations, and many of the implicated agents are used to treat non-cardiac conditions." | 2.40 | Drug-induced cardiac arrhythmias: incidence, prevention and management. ( Doig, JC, 1997) |
| " Conversion to sinus rhythm was achieved in 16 out of 22 hemodynamically stable children with a dosage of 4." | 1.30 | Sotalol for atrial tachycardias after surgery for congenital heart disease. ( Beaufort-Krol, GC; Bink-Boelkens, MT, 1997) |
| "In the d,l-sotalol- and erythromycin-treated hearts, torsades de pointes occurred only in the presence of hypokalemia and bradycardia, whereas, in the presence of clofilium, bradycardia alone caused torsades de pointes." | 1.30 | Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin. ( Borggrefe, M; Breithardt, G; Clague, JR; Eckardt, L; Haverkamp, W; Johna, R; Mertens, H, 1998) |
| "On sotalol, VT was initiated in only one." | 1.28 | Dual chamber rate responsive pacing to allow sotalol therapy for ventricular tachycardia. ( Davis, MJ; Horrigan, MC; May, C; Smith, P, 1992) |
| " The effects of six beta-adrenoceptive antagonists [(+/-)-propranolol, (+)-propranolol, (+/-)-sotalol, (+/-)-practolol, (+/-)-pindolol and (+/-)-procinolol] were studied on airway resistance and heart rate in guinea-pigs and dose-response curves constructed." | 1.25 | Comparative study of six -adrenoceptive antagonists on airway resistance and heart rate in the guinea-pig. ( Advenier, C; Boissier, JR; Giudicelli, JF, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 11 (42.31) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Biswas, M | 1 |
| Levy, A | 1 |
| Weber, R | 1 |
| Tarakji, K | 1 |
| Chung, M | 1 |
| Noseworthy, PA | 1 |
| Newton-Cheh, C | 1 |
| Rosenberg, MA | 1 |
| Van Gelder, IC | 1 |
| Rienstra, M | 1 |
| Crijns, HJ | 1 |
| Olshansky, B | 1 |
| Capucci, A | 1 |
| Botto, G | 1 |
| Molon, G | 1 |
| Spampinato, A | 1 |
| Favale, S | 1 |
| Proclemer, A | 1 |
| Porfilio, A | 1 |
| Marotta, T | 1 |
| Vimercati, M | 1 |
| Boriani, G | 1 |
| Shah, A | 1 |
| Moon-Grady, A | 1 |
| Bhogal, N | 1 |
| Collins, KK | 1 |
| Tacy, T | 1 |
| Brook, M | 1 |
| Hornberger, LK | 1 |
| Rajawat, YS | 1 |
| Patel, VV | 1 |
| Gerstenfeld, EP | 1 |
| Nayak, H | 1 |
| Marchlinski, FE | 1 |
| Leaver, SK | 1 |
| Ho, TB | 1 |
| Brunckhorst, CB | 1 |
| Stockburger, M | 1 |
| Gerhardt, L | 1 |
| Helms, S | 1 |
| Schlegl, M | 1 |
| Butter, C | 1 |
| Eibs, HG | 1 |
| Oberdisse, U | 1 |
| Brambach, U | 1 |
| Kelcher, S | 1 |
| Fernandes, CM | 1 |
| Daya, MR | 1 |
| Jacquet, L | 1 |
| Evenepoel, M | 1 |
| Marenne, F | 1 |
| Evrard, P | 1 |
| Verhelst, R | 1 |
| Dion, R | 1 |
| Goenen, M | 1 |
| Beaufort-Krol, GC | 1 |
| Bink-Boelkens, MT | 1 |
| Doig, JC | 1 |
| Chung, MK | 1 |
| Schweikert, RA | 1 |
| Wilkoff, BL | 1 |
| Niebauer, MJ | 1 |
| Pinski, SL | 1 |
| Trohman, RG | 1 |
| Kidwell, GA | 1 |
| Jaeger, FJ | 1 |
| Morant, VA | 1 |
| Miller, DP | 1 |
| Tchou, PJ | 1 |
| Eckardt, L | 1 |
| Haverkamp, W | 1 |
| Mertens, H | 1 |
| Johna, R | 1 |
| Clague, JR | 1 |
| Borggrefe, M | 1 |
| Breithardt, G | 1 |
| Dionisio, P | 1 |
| Stroobandt, R | 1 |
| Vandenbulcke, F | 1 |
| Sinnaeve, A | 1 |
| Kähkönen, S | 1 |
| Kaartinen, M | 1 |
| Juhela, P | 1 |
| Horrigan, MC | 1 |
| Davis, MJ | 1 |
| May, C | 1 |
| Smith, P | 1 |
| Beyer, ME | 1 |
| Hoffmeister, HM | 1 |
| Seipel, L | 1 |
| Weissenburger, J | 1 |
| Davy, JM | 1 |
| Chézalviel, F | 1 |
| Ertzbischoff, O | 1 |
| Poirier, JM | 1 |
| Engel, F | 1 |
| Lainée, P | 1 |
| Penin, E | 1 |
| Motté, G | 1 |
| Cheymol, G | 2 |
| Babin, JP | 1 |
| Carre, M | 1 |
| Martin, C | 1 |
| Gupta, K | 1 |
| Mouillé, P | 1 |
| Laubie, M | 1 |
| Schmitt, H | 1 |
| Advenier, C | 1 |
| Boissier, JR | 1 |
| Giudicelli, JF | 1 |
2 reviews available for sotalol and Bradycardia
| Article | Year |
|---|---|
Rate control in atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Age Factors; Amiodarone; Anti-Arrhythmia Agents; Atenolol; Atrial Fibri | 2016 |
Drug-induced cardiac arrhythmias: incidence, prevention and management.
Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-Infective Agents; | 1997 |
3 trials available for sotalol and Bradycardia
21 other studies available for sotalol and Bradycardia
| Article | Year |
|---|---|
Multicenter Analysis of Dosing Protocols for Sotalol Initiation.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Drug D | 2020 |
Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias.
Topics: Abortion, Induced; Anti-Arrhythmia Agents; Atrial Flutter; Bradycardia; Catheter Ablation; Digoxin; | 2012 |
Advantages and pitfalls of combining device-based and pharmacologic therapies for the treatment of ventricular arrhythmias: observations from a tertiary referral center.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bradycardia; Combined Modality Therapy; Defibrillators, Implanta | 2004 |
Inadvertent toxic drug reaction in the management of atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Digoxin; Drug Interactions; Electrocardiog | 2006 |
[Conversion to sinus rhythm].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Diagnosis, Differential; Diarrhea; Electri | 2006 |
[Intoxication with beta-receptor blockers (author's transl)].
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Antidotes; Bradycardia; Bundle-Branch Block; Buprano | 1982 |
Taking age into account.
Topics: Aged; Aged, 80 and over; Aging; Bradycardia; Creatinine; Female; Humans; Kidney; Renal Circulation; | 1995 |
Sotalol-induced bradycardia reversed by glucagon.
Topics: Aged; Aged, 80 and over; Bradycardia; Electrocardiography; Female; Glucagon; Humans; Sotalol | 1995 |
Sotalol for atrial tachycardias after surgery for congenital heart disease.
Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Bradycardi | 1997 |
Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia | 1998 |
Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin.
Topics: Animals; Bradycardia; Electrocardiography; Erythromycin; Hypokalemia; In Vitro Techniques; Male; Qua | 1998 |
Rate adaptive dual chamber pacing: inappropriate rate response due to pseudomalfunction of the QT biosensor.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Bradycardia; Cardiac Pacing, | 1999 |
Permanent pacing-aid to carry out long-term lithium therapy in manic patient with symptomatic bradycardia.
Topics: Adrenergic beta-Antagonists; Aged; Antimanic Agents; Atenolol; Bipolar Disorder; Bradycardia; Glauco | 2000 |
Which beta-blocker?
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Heart Failure; Huma | 2001 |
Dual chamber rate responsive pacing to allow sotalol therapy for ventricular tachycardia.
Topics: Bradycardia; Cardiac Pacing, Artificial; Female; Humans; Male; Middle Aged; Pacemaker, Artificial; S | 1992 |
Hemodynamic effects of cibenzoline on normal myocardium and after pretreatment with DL-sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Bradycardia; Cardiac Output; Dose-Response Relation | 1992 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, A | 1991 |
[Possible embryofetopathy caused by beta-blocker (sotalol) taken throughout the pregnancy].
Topics: Abnormalities, Drug-Induced; Adult; Bradycardia; Cardiac Complexes, Premature; Facial Bones; Female; | 1985 |
Hazards of B-blockers in the elderly: severe bradycardia due to Sotacor overdose.
Topics: Aged; Bradycardia; Electrocardiography; Female; Humans; Hypertension; Sotalol | 1985 |
[Comparative study of chronotropic and inotropic effects of different beta adrenolytic drugs].
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Bradycardia; Dogs; Drug Antagoni | 1972 |
Comparative study of six -adrenoceptive antagonists on airway resistance and heart rate in the guinea-pig.
Topics: Acetanilides; Adrenergic beta-Antagonists; Airway Resistance; Alcohols; Animals; Bradycardia; Bronch | 1972 |