sotalol has been researched along with Blood Pressure, Low in 10 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sotalol is an antiarrhythmic agent with combined beta-blocking and class III antiarrhythmic properties." | 6.68 | Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group. ( Das, G; Falk, R; Hanyok, JJ; Hardy, SA; Karagounis, L; Platia, E; Sung, RJ; Tan, HL, 1995) |
| "The relative safety and efficacy of intravenous administration of adenosine, lignocaine, disopyramide, flecainide, and sotalol for termination of stable, induced ventricular tachycardia was assessed in serial trials." | 5.06 | Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia. ( Camm, AJ; Garratt, CJ; Griffith, MJ; Linker, NJ; Ward, DE, 1990) |
| "Sotalol is an antiarrhythmic agent with combined beta-blocking and class III antiarrhythmic properties." | 2.68 | Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group. ( Das, G; Falk, R; Hanyok, JJ; Hardy, SA; Karagounis, L; Platia, E; Sung, RJ; Tan, HL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zena, LA | 1 |
| da Silva, GS | 1 |
| Gargaglioni, LH | 1 |
| Bícego, KC | 1 |
| Leaver, SK | 1 |
| Ho, TB | 1 |
| Eibs, HG | 1 |
| Oberdisse, U | 1 |
| Brambach, U | 1 |
| Sung, RJ | 1 |
| Tan, HL | 1 |
| Karagounis, L | 1 |
| Hanyok, JJ | 1 |
| Falk, R | 1 |
| Platia, E | 1 |
| Das, G | 1 |
| Hardy, SA | 1 |
| Owens, P | 1 |
| O'Brien, E | 1 |
| Gauthier, P | 1 |
| Nadeau, RA | 1 |
| de Champlain, J | 2 |
| Neuvonen, PJ | 1 |
| Elonen, E | 1 |
| Tarssanen, L | 1 |
| Griffith, MJ | 1 |
| Linker, NJ | 1 |
| Garratt, CJ | 1 |
| Ward, DE | 1 |
| Camm, AJ | 1 |
| Warren, R | 1 |
| Vohra, J | 1 |
| Hunt, D | 1 |
| Hamer, A | 1 |
| Bouvier, M | 1 |
| Drolet, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "PGDT With the Hypotension Prediction Index to Reduce the Number and Duration of Intraoperative Hypotension and the Incidence of Renal Failure in Patients Undergoing Lung Surgery"[NCT04149314] | 142 participants (Actual) | Interventional | 2019-11-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for sotalol and Blood Pressure, Low
| Article | Year |
|---|---|
Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group.
Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Dose-Response Relationship, | 1995 |
Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia.
Topics: Adenosine; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramid | 1990 |
8 other studies available for sotalol and Blood Pressure, Low
| Article | Year |
|---|---|
Baroreflex regulation affects ventilation in the cururu toad Rhinella schneideri.
Topics: Animals; Anura; Atropine; Baroreflex; Blood Pressure; Heart Rate; Hyperoxia; Hypotension; Nitropruss | 2016 |
Inadvertent toxic drug reaction in the management of atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Digoxin; Drug Interactions; Electrocardiog | 2006 |
[Intoxication with beta-receptor blockers (author's transl)].
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Antidotes; Bradycardia; Bundle-Branch Block; Buprano | 1982 |
Hypotension in patients with coronary disease: can profound hypotensive events cause myocardial ischaemic events?
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Amb | 1999 |
Cardiac reflex activity in chemically sympathectomized dogs in response to hypotension or hypertension.
Topics: Animals; Arrhythmia, Sinus; Dogs; Female; Heart Rate; Hydroxydopamines; Hypertension; Hypotension; M | 1977 |
Sotalol intoxication, two patients with concentration-effect relationships.
Topics: Adult; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; Half-Life; Human | 1979 |
Serious interactions of sotalol with amiodarone and flecainide.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Drug Administration Schedule; Drug Interactions; Drug Therap | 1990 |
Abnormal regulation of the sympathoadrenal system in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Adrenal Medulla; Animals; Blood Pressure; Desoxycorticosterone; Epinephrine; Heart Rate; Hypertensio | 1987 |