Page last updated: 2024-11-04

sotalol and Auricular Fibrillation

sotalol has been researched along with Auricular Fibrillation in 324 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
" Sotalol is a nonselective β-adrenergic receptor antagonist with class III antiarrhythmic properties that has been mostly used for atrial fibrillation treatment and suppressing recurrent ventricular tachyarrhythmias."9.41The Arrhythmogenicity of Sotalol and its Role in Heart Failure: A Literature Review. ( Alvarez, C; Augustin, N; Kluger, J, 2023)
"Sotalol is recommended to prevent relapse of atrial fibrillation after cardioversion (CV)."9.22Reduction over time of QTc prolongation in patients with sotalol after cardioversion of atrial fibrillation. ( Darpö, B; Ferber, G; Frick, M; Lenhoff, H; Rosenqvist, M, 2016)
"Sotalol is a commonly prescribed antiarrhythmic drug (AAD) used for maintaining sinus rhythm in patients with atrial fibrillation (AF)."9.19Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease. ( Al-Khatib, SM; Allen-LaPointe, N; Anstrom, KJ; Daubert, JP; DeWald, T; Horton, JR; Lokhnygina, Y; Peterson, ED; Piccini, JP; Shaw, LK; Steinberg, BA; Thomas, K; Wojdyla, DM, 2014)
" The aim of our study was to compare sotalol (S) versus beta-blocking agents (BB) in terms of prevention of ATA, cardioversions (CVs), and cardiovascular hospitalizations (H) in patients paced for bradycardia-tachycardia form of sinus node disease (BT-SND)."9.13The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker. ( Boriani, G; Botto, G; Capucci, A; Favale, S; Marotta, T; Molon, G; Porfilio, A; Proclemer, A; Spampinato, A; Vimercati, M, 2008)
"To evaluate the effects and adverse reactions of amiodarone and sotalol in treatment of atrial fibrillation."9.12[Effects of amiodarone versus sotalol in treatment of atrial fibrillation: a random controlled clinical study]. ( Chen, YX; Guo, WL; Huang, CX; Jiang, H; Jin, CR; Liu, ZM; Niu, F; Yang, B, 2006)
"To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients with symptomatic persistent atrial fibrillation, adequate anticoagulant therapy, and planned electrical cardioversion."9.12Azimilide vs. placebo and sotalol for persistent atrial fibrillation: the A-COMET-II (Azimilide-CardiOversion MaintEnance Trial-II) trial. ( Borggrefe, M; Lombardi, F; Lüderitz, B; Ruzyllo, W, 2006)
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."9.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
"Patients (n=187) with symptomatic persistent atrial fibrillation at the background of ischemic heart disease after restoration of sinus rhythm were randomized for treatment with sotalol 80 - 160 mg/day (n=48), or with combinations of sotalol with perindopril 4 - 8 mg/day (n=48), rosuvastatin 5 - 20 mg/day (n=45), or omega-3 polyunsaturated fatty acids containing preparation 1 g/day (n=45)."9.12[Influence of perindopril, rosuvastatin, or omega-3 polyunsaturated fatty acids on efficacy of antirecurrence therapy with sotalol in patients with persistent atrial fibrillation]. ( Bodrikova, VV; Kanorskaia, IuS; Kanorskiĭ, SG, 2007)
"Amiodarone and sotalol are commonly used for the maintenance of sinus rhythm, but the efficacy of these agents administered as high-dose infusions for rapid conversion of atrial fibrillation is unknown."9.11Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial. ( Cooper, MJ; Crampton, R; Eipper, V; Guy, D; Kijvanit, P; Ross, DL; Thomas, SP; Wallace, E, 2004)
"Oral low-dose sotalol provides a considerable reduction in the occurrence of atrial fibrillation."9.11Preoperative use of sotalol versus atenolol for atrial fibrillation after cardiac surgery. ( Blasco, M; Carbonell, N; Jordá, A; Martínez-León, J; Núñez, J; Otero, E; Sanjuán, R, 2004)
"These results show that MgCl(2), in addition to sotalol, is not more effective than sotalol alone in the prevention of tachyarrhythmias after CABG."9.11Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery. ( Beukema, WP; Geertman, H; Sie, HT; van der Starre, PJ; van Rooyen-Butijn, M, 2004)
" We investigated the effects of pretreatment with oral d,l-sotalol on rate-dependent changes in atrial monophasic action potential (MAP) duration after cardioversion of chronic AF with reference to the efficacy in preventing the arrhythmia recurrence."9.11Sotalol reverses remodeled action potential in patients with chronic atrial fibrillation but does not prevent arrhythmia recurrence. ( Ito, A; Kodama, I; Osaka, T; Yamazaki, M; Yokoyama, E, 2004)
"This prospective, randomized, double-blind, placebo-controlled study compared the efficacy and safety of amiodarone and sotalol in the prevention of atrial fibrillation (AF) following open heart surgery."9.11Amiodarone versus sotalol for the treatment of atrial fibrillation after open heart surgery: the Reduction in Postoperative Cardiovascular Arrhythmic Events (REDUCE) trial. ( Arcidi, JM; Hilleman, DE; Lenz, TL; Mohiuddin, SM; Mooss, AN; Packard, KA; Rovang, KS; Sugimoto, JT; Wurdeman, RL, 2004)
"This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation."9.11Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation. ( Chlouverakis, GI; Hamilos, ME; Igoumenidis, NE; Klapsinos, NC; Kochiadakis, GE; Tzerakis, PG; Vardas, PE, 2004)
"Flecainide and sotalol prolong the atrial action potential during atrial fibrillation in humans."9.11Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation. ( Breithardt, G; Eckardt, L; Engelen, M; Franz, MR; Haverkamp, W; Kirchhof, P; Ribbing, M; Wasmer, K, 2005)
"In this double-blind, placebo-controlled trial, we randomly assigned 665 patients who were receiving anticoagulants and had persistent atrial fibrillation to receive amiodarone (267 patients), sotalol (261 patients), or placebo (137 patients) and monitored them for 1 to 4."9.11Amiodarone versus sotalol for atrial fibrillation. ( Atwood, JE; Ezekowitz, MD; Fletcher, RD; Harris, CL; Jacobson, AK; Lewis, HD; Lopez, B; Raisch, DW; Reda, DJ; Sharma, SC; Singh, BN; Singh, SN; Tang, XC, 2005)
"The Sotalol-Amiodarone Fibrillation Efficacy Trial (SAFE-T) is a randomized, double-blind, multicenter, placebo-controlled trial in which the effects of sotalol and amiodarone in maintaining stability of sinus rhythm are being examined in patients with persistent atrial fibrillation at 20 Veterans Affairs medical centers."9.10Comparison of sotalol versus amiodarone in maintaining stability of sinus rhythm in patients with atrial fibrillation (Sotalol-Amiodarone Fibrillation Efficacy Trial [Safe-T]). ( Antman, EM; Atwood, JE; Ezekowitz, MD; Falk, RH; Fletcher, RD; Fye, CL; Jacobson, AK; Lewis, HD; Lopez, B; Reda, DJ; Sharma, SC; Singh, BN; Singh, SN; Tang, XC, 2003)
"For patients in whom antiarrhythmic drug therapy is indicated, low dose amiodarone significantly reduces atrial fibrillation-related costs by reducing the number of atrial fibrillation-related procedures."9.10Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial. ( Couturier, A; Dubuc, M; Frasure-Smith, N; Gagné, P; Lambert, J; Lumer, GB; Nattel, S; Roy, D; Talajic, M; Thibault, B, 2002)
"To compare sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation."9.09An open label, randomised, crossover study comparing sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation. ( Birchall, AS; Channer, KS; Smith, M; Steeds, RP, 1999)
"The purpose of this prospective, randomized, double-blind, placebo-controlled study was to assess the efficacy of preoperatively and postoperatively administered oral d,l sotalol in preventing the occurrence of postoperative atrial fibrillation (AF)."9.09Oral d,l sotalol reduces the incidence of postoperative atrial fibrillation in coronary artery bypass surgery patients: a randomized, double-blind, placebo-controlled study. ( Chao, S; Ergin, A; Gomes, JA; Ip, J; Lansman, S; Mehta, D; Newhouse, TT; Pe, E; Santoni-Rugiu, F, 1999)
"Currently d,l-sotalol is widely used to prevent recurrence of atrial fibrillation and/or atrial flutter, although a randomized dose-response study has not previously been conducted to guide therapy for this indication."9.09Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with symptomatic atrial fibrillation and/or atrial flutter. d,l-Sotalol Atrial Fibrillation/Flutter Study Group. ( Benditt, DG; Browne, K; Chang-Sing, P; Deering, TF; Jin, J; Singh, BN; Williams, JH; Zucker, R, 1999)
"To compare the efficacy and safety of sotalol and quinidine after conversion of atrial fibrillation (AF) of <6 months, a prospective multicenter trial enrolled 121 patients who were randomized to receive dl-sotalol (160 to 320 mg/day, 58 patients) or quinidine sulfate (600 to 800 mg/day, 63 patients)."9.09Efficacy and safety of sotalol versus quinidine for the maintenance of sinus rhythm after conversion of atrial fibrillation. SOCESP Investigators. The Cardiology Society of São Paulo. ( de Paola, AA; Veloso, HH, 1999)
"We undertook a prospective, multicenter trial to test the hypothesis that low doses of amiodarone would be more efficacious in preventing recurrent atrial fibrillation than therapy with sotalol or propafenone."9.09Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators. ( Connolly, S; Dorian, P; Dubuc, M; Eisenberg, MJ; Gagné, P; Green, M; Kus, T; Lambert, J; Nattel, S; Roy, D; Talajic, M; Thibault, B, 2000)
"A prospective, randomized controlled trial of new-onset atrial fibrillation was conducted to compare the efficacy and safety of sotalol and amiodarone (active treatment) with rate control by digoxin alone for successful reversion to sinus rhythm at 48 hours."9.09A prospective, randomized controlled trial comparing the efficacy and safety of sotalol, amiodarone, and digoxin for the reversion of new-onset atrial fibrillation. ( Joseph, AP; Ward, MR, 2000)
"In patients with persistent atrial fibrillation, oral treatment with magnesium alone or as an adjuvant to sotalol, does not influence the recurrence rate of atrial fibrillation after elective cardioversion."9.09The effect of oral magnesium, alone or as an adjuvant to sotalol, after cardioversion in patients with persistent atrial fibrillation. ( Darpö, B; Frick, M; Ostergren, J; Rosenqvist, M, 2000)
"To assess and compare the safety and efficacy of amiodarone and sotalol in the treatment of patients with recurrent symptomatic atrial fibrillation."9.09Low dose amiodarone and sotalol in the treatment of recurrent, symptomatic atrial fibrillation: a comparative, placebo controlled study. ( Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Simantirakis, EN; Vardas, PE, 2000)
"This randomized study compared the efficacy and safety of amiodarone, propafenone and sotalol in the prevention of atrial fibrillation."9.09Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm? ( Chrysostomakis, SI; Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Mavrakis, HE; Vardas, PE, 2000)
"To compare the effects of sotalol and metoprolol on heart rate, during isotonic (ITE) and isometric (IME) exercise and daily activities, in digitalized patients with chronic atrial fibrillation."9.09Sotalol vs metoprolol for ventricular rate control in patients with chronic atrial fibrillation who have undergone digitalization: a single-blinded crossover study. ( Igoumenidis, NE; Kalebubas, MD; Kanoupakis, EM; Kochiadakis, GE; Mavrakis, HE; Vardakis, KE; Vardas, PE, 2001)
"The purpose of the study was to compare the efficacy and safety of sotalol and bisoprolol in the maintenance of sinus rhythm after electrical cardioversion of atrial fibrillation."9.09Maintenance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation; sotalol vs bisoprolol. ( Alt, EU; Lehmann, G; Ndrepepa, G; Plewan, A; Schmitt, C; Schömig, A; Schreieck, J, 2001)
"This study was performed to evaluate, using a randomized double-blind, placebo-controlled protocol, the long-term efficacy and safety of propafenone and sotalol in maintaining sinus rhythm after conversion of recurrent symptomatic atrial fibrillation (AF)."9.09Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation. ( Bellandi, F; Dabizzi, RP; Frascarelli, F; Giovannini, T; Leoncini, M; Maioli, M; Simonetti, I, 2001)
"We assessed the efficacy of postoperatively administered oral Sotalol in preventing the occurrence of postoperative atrial fibrillation."9.09Effect of Sotalol in the prevention of atrial fibrillation following coronary artery bypass grafting. ( Ishida, K; Matsuura, K; Sudo, Y; Takahara, Y, 2001)
"This study compared the efficacy and safety of sotalol and quinidine for conversion and prevention of recurrent atrial fibrillation."9.08Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine. ( Baedeker, F; Hohnloser, SH; van de Loo, A, 1995)
"Aim of the present study was to assess the efficacy and safety of flecainide (F) and sotalol (S) for the prevention of recurrences of paroxysmal atrial fibrillation (PAF)."9.08[A comparison between flecainide and sotalol in the prevention of recurrences of paroxysmal atrial fibrillation]. ( Burattini, M; Carunchio, A; Ceci, V; Fera, MS; Galati, A; Greco, G; Mazza, A, 1995)
"We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment."9.08Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995)
"To assess the propafenone and sotalol efficacy in the prevention of paroxysmal atrial fibrillation (FA) we enrolled, in a double blind placebo controlled study over 1 year, 300 patients (168 males); mean age 52."9.08[Propafenone and sotalol: long-term efficacy and tolerability in the prevention of paroxysmal atrial fibrillation. A placebo-controlled double-blind study]. ( Bellandi, F; Cantini, F; Dabizzi, RP; Niccoli, L; Palchetti, R, 1996)
"The main goal of this study is to evaluate the safety and efficacy of propafenone versus sotalol as an initial choice of treatment in patients with symptomatic paroxysmal atrial fibrillation (AF), according to a double-blind randomized system."9.08Comparisons of oral propafenone and sotalol as an initial treatment in patients with symptomatic paroxysmal atrial fibrillation. ( Chang, MS; Chen, SA; Chen, YJ; Cheng, JJ; Chiang, CE; Fong, AN; Huang, JL; Lee, SH; Tai, CT; Wen, ZC; Yu, WC, 1997)
"Sotalol's usefulness in treatment of atrial fibrillation and atrial flutter is unproven."9.08Efficacy and safety of sotalol in patients with refractory atrial fibrillation or flutter. ( Ferrick, KJ; Fisher, JD; Gallik, DM; Kim, SG; Roth, JA, 1997)
"To compare the safety and efficacy of amiodarone and sotalol in the treatment of patients with recurrent symptomatic atrial fibrillation (AF), 70 patients were entered into a randomized, double-blind study."9.08Low-dose amiodarone versus sotalol for suppression of recurrent symptomatic atrial fibrillation. ( Igoumenidis, NE; Kanoupakis, EM; Kochiadakis, GE; Marketou, ME; Solomou, MC; Vardas, PE, 1998)
"To analyze the recurrences of atrial fibrillation in patients treated with sotalol or quinidine."9.08[Analysis of atrial fibrillation recurrence during therapy with sotalol or quinidine. Researchers of +SOCESP]. ( de Paola, AA; Veloso, HH, 1998)
"This study sought to compare the efficacy and safety of intravenous flecainide and sotalol for immediate cardioversion of atrial fibrillation."9.08Prospective comparison of flecainide versus sotalol for immediate cardioversion of atrial fibrillation. ( Ebner, A; Gatterer, E; Gattermeier, M; Heinze, G; Hohenwallner, W; Kratzer, H; Kuhn, P; Lenz, K; Poelzl, G; Reisinger, J; Slany, J; Wiesinger, K; Zeindlhofer, E, 1998)
"Thus, a selective approach based on a clinical risk prediction algorithm should improve the cost-effectiveness and safety of low-dose sotalol in the prevention of atrial fibrillation after coronary bypass surgery."9.08Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification? A prospective placebo-controlled study using low-dose sotalol. ( Buser, P; Huber, M; Osswald, S; Pfisterer, M; Schmidhauser, C; Skarvan, K; Stulz, P; Weber, UK, 1998)
"The purpose of our study (conducted between August 1995 and September 1996) was to evaluate prospectively the efficacy of intravenous administration (in 10 min) of sotalol, flecainide or the combination of these drugs to restore sinus rhythm in patients (without cardiac/pulmonary failure) who came to the First Heart Aid of our hospital with atrial fibrillation lasting less than 24 h."9.08Treatment of recent onset atrial fibrillation with intravenous sotalol and/or flecainide. ( Braat, SH; Heymeriks, J; Peters, FP; Wellens, HJ, 1998)
"To compare the efficacy and safety of a single dose of ibutilide, a new class III antiarrhythmic drug, with that of DL-sotalol in terminating chronic atrial fibrillation or flutter in haemodynamically stable patients."9.08Superiority of ibutilide (a new class III agent) over DL-sotalol in converting atrial flutter and atrial fibrillation. The Ibutilide/Sotalol Comparator Study Group. ( Golitsyn, SR; Harry, JD; Perry, KT; Ruda, MY; Stangl, K; Steinbeck, G; Touboul, P; Van Wijk, LV; Vos, MA; Wellens, HJ, 1998)
"To establish the value of adjuvant dl-sotalol to digoxin for control of the ventricular response in chronic atrial fibrillation, 60 patients were evaluated in a multicenter, randomized, double-blind, parallel, placebo-controlled study."9.07Comparative effects of the combination of digoxin and dl-sotalol therapy versus digoxin monotherapy for control of ventricular response in chronic atrial fibrillation. dl-Sotalol Atrial Fibrillation Study Group. ( Bellinger, R; Brodsky, M; Powers, L; Saini, R; Weiss, R; Zoble, R, 1994)
"This study investigated the hemodynamic effects of oral sotalol during both sinus rhythm and paroxysmal atrial fibrillation."9.07Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation. ( Alboni, P; Chioin, R; Fucà, G; Paparella, N; Pedini, I; Razzolini, R; Scarfò, S, 1993)
"This open, parallel-group study compares quinidine and sotalol treatment for maintenance of sinus rhythm after direct current conversion of patients with chronic atrial fibrillation."9.06Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation. ( Edvardsson, N; Juul-Möller, S; Rehnqvist-Ahlberg, N, 1990)
"The efficacy of sotalol in treating acute atrial fibrillation and flutter after open heart surgery was compared with that of a digoxin/disopyramide combination."9.05Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass. Comparison with disopyramide and digoxin in a randomised trial. ( Campbell, TJ; Gavaghan, TP; Morgan, JJ, 1985)
"To assess the clinical and cost-effectiveness of magnesium sulphate compared with sotalol, and to assess the clinical effectiveness of magnesium sulphate compared with placebo in the prevention of atrial fibrillation (AF) in patients who have had a coronary artery bypass graft (CABG)."8.84Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation. ( Frampton, GK; Jones, J; Price, A; Shepherd, J; Tanajewski, L; Turner, D, 2008)
"Many clinicians choose sotalol for the prevention of recurrences of atrial fibrillation (AF) as an alternative to quinidine, which has been associated with an increase in long-term mortality."8.80Comparison of sotalol versus quinidine for maintenance of normal sinus rhythm in patients with chronic atrial fibrillation. ( Bauman, J; Southworth, MR; Viana, M; Zarembski, D, 1999)
"The DASH-AF (Feasibility and Safety of Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients With Atrial Fibrillation) trial evaluates the safety and feasibility of intravenous (IV) sotalol, achieving a steady state with maximum QTc prolongation within 6 hours instead of the traditional 5-dose inpatient oral (PO) titration."8.31Feasibility and Safety of Intravenous Sotalol Loading in Adult Patients With Atrial Fibrillation (DASH-AF). ( Ahmed, A; Atkins, D; Bawa, D; Bommana, S; Bush, J; Charate, R; Darden, D; Garg, J; Gopinathannair, R; Kabra, R; Kennedy, R; Koreber, S; Lakkireddy, D; Mohanty, S; Natale, A; Park, P; Pothineni, NVK; Seo, BW; Tummala, R; Vasamreddy, C, 2023)
"Amiodarone, the most effective antiarrhythmic drug in atrial fibrillation, inhibits apixaban and rivaroxaban elimination, thus possibly increasing anticoagulant-related risk for bleeding."8.31Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study. ( Chung, CP; Daugherty, JR; Dickson, AL; Dupont, WD; Hung, AM; Murray, KT; Ray, WA; Smalley, W; Stein, CM; Zimmerman, E, 2023)
"Sotalol and dronedarone are both used for maintenance of sinus rhythm for patients with atrial fibrillation."8.31Dronedarone Versus Sotalol in Antiarrhythmic Drug-Naive Veterans With Atrial Fibrillation. ( Blomström-Lundqvist, C; Camm, AJ; Din, N; Fan, J; Kabadi, S; Kowey, P; Pundi, K; Rashkin, J; Sandhu, AT; Singh, JP; Turakhia, MP; Wieloch, M, 2023)
"Use of d,l-sotalol for rhythm control in patients with atrial fibrillation (AF) has raised safety concerns."8.31Mortality and ventricular arrhythmias in patients on d,l-sotalol for rhythm control of atrial fibrillation: A nationwide cohort study. ( Darpo, B; Frick, M; Järnbert-Petersson, H; Lenhoff, H; Tornvall, P, 2023)
"There exists variability in the administration of in-patient sotalol therapy for symptomatic atrial fibrillation (AF)."8.12Economics and outcomes of sotalol in-patient dosing approaches in patients with atrial fibrillation. ( B Muhlestein, J; Burnham, TS; Jared Bunch, T; L Anderson, J; L Bair, T; Steinberg, BA; T May, H; U Knowlton, K; Varela, DL, 2022)
"We aimed to evaluate the effectiveness and safety of dronedarone versus sotalol in real-world practice in Asian patients with atrial fibrillation (AF)."7.96Comparative clinical outcomes of dronedarone and sotalol in Asian patients with atrial fibrillation: a nationwide cohort study. ( Choi, EK; Kim, JA; Kim, JH; Kwon, TY; Lee, SR; Lee, YE; Oh, S, 2020)
"To evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF)."7.88Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation. ( Broux, B; De Clercq, D; Decloedt, A; Deprez, P; van Loon, G; Van Steenkiste, G; Ven, S; Vera, L, 2018)
"Our objective was to evaluate the efficacy and safety of intravenous (IV) sotalol in the treatment of incessant tachyarrhythmias in children with normal cardiac function."7.85Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children. ( Ge, H; Jiang, H; Li, X; Liu, H; Zhang, Y, 2017)
"To evaluate the efficacy of sotalol depending on the magnitude of changes in adrenal responsiveness and autonomic nervous system tone in patients with paroxysmal atrial fibrillation (AF)."7.83[A change in adrenal responsiveness in sotalol-treated patients with paroxysmal atrial fibrillation depending on autonomic nervous system tone]. ( Afanasyev, SA; Batalov, RE; Borisova, EV; Kisteneva, IV; Popov, SV; Rebrova, TY, 2016)
"Sotalol and amiodarone are commonly prescribed antiarrhythmics for the treatment of post-operative atrial fibrillation (POAF)."7.83Mortality risk of sotalol and amiodarone for post-CABG atrial fibrillation. ( Brophy, JM; Johnson, SM, 2016)
"To estimate cost-effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation (AF)."7.81Analysis of the cost-effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia. ( Jankovic, SM; Kostic, M; Paunovic, D; Tesic, D, 2015)
"Inpatient antiarrhythmic drug initiation for atrial fibrillation is mandated for dofetilide (DF) and is often performed for sotalol (SL), particularly if proarrhythmia risk factors are present."7.81Risk prediction for adverse events during initiation of sotalol and dofetilide for the treatment of atrial fibrillation. ( Agusala, K; Caprio, T; Kulkarni, C; Oesterle, A; Passman, R; Subacius, H, 2015)
"Ranolazine is evaluated for antiarrhythmic therapy of atrial fibrillation (AF)."7.79Antiarrhythmic effect of ranolazine in combination with class III drugs in an experimental whole-heart model of atrial fibrillation. ( Breithardt, G; Eckardt, L; Frommeyer, G; Kaese, S; Kaiser, D; Milberg, P; Uphaus, T, 2013)
"In several clinical and pre-clinical studies, application of ranolazine (RAN) led to suppression of atrial fibrillation (AF)."7.79Sodium channel block by ranolazine in an experimental model of stretch-related atrial fibrillation: prolongation of interatrial conduction time and increase in post-repolarization refractoriness. ( Belardinelli, L; Breithardt, G; Eckardt, L; Frommeyer, G; Ghezelbash, S; Milberg, P; Osada, N; Rajamani, S; Razvan, R, 2013)
" The aim of this study was to determine the effects of IPC versus intravenous (IV) d,l-sotalol and flecainide infusion on transmural atrial electrophysiology and sustained atrial fibrillation (AF) in the goat."7.75Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation. ( Accord, RE; Allessie, MA; Hermans, JJ; Maessen, JG; Schotten, U; Smits, JF; van Brakel, TJ, 2009)
" The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy."7.75Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009)
"This study evaluated antiarrhythmic effects of d,l-sotalol in a canine atrial fibrillation (AF) model with left ventricular dysfunction."7.75d,l-Sotalol reverses abbreviated atrial refractoriness and prevents promotion of atrial fibrillation in a canine model with left ventricular dysfunction induced by atrial tachypacing. ( Fujiki, A; Hashimoto, N; Inoue, H; Mizumaki, K; Nakatani, Y; Sakabe, M; Sakamoto, T, 2009)
"Sotalol is a class III antiarrhythmic agent that is highly effective for tachyarrhythmias in adults, but its efficacy in patients with congenital heart disease (CHD) remains unclear."7.74Efficacy and safety of sotalol for refractory tachyarrhythmias in congenital heart disease. ( Kamakura, S; Kurosaki, K; Miyazaki, A; Ohuchi, H; Yagihara, T; Yamada, O, 2008)
" Antiarrhythmic therapy with sotalol at 240 mg/day was started, and after 48 h the patient experienced several episodes of sustained torsade de pointes, dramatic marked QT interval prolongation and negative T wave, in absence of overt cardiac disease, renal failure, electrolyte abnormalities or baseline QT interval prolongation."7.73Sustained torsade de pointes occurring early during oral sotalol therapy for atrial fibrillation recurrence prophylaxis in a patient without heart disease. ( Boldini, A; Brentana, L; D'Aloia, A; Dei Cas, L; Faggiano, P; Pedrinazzi, C; Procopio, R, 2005)
"The combination of sotalol and magnesium can significantly reduce the incidence of post-operative atrial fibrillation following coronary surgery."7.73Does prophylactic sotalol and magnesium decrease the incidence of atrial fibrillation following coronary artery bypass surgery: a propensity-matched analysis. ( Aerra, V; Fabri, BM; Grayson, AD; Kuduvalli, M; Moloto, AN; Oo, AY; Srinivasan, AK, 2006)
"We present 4 patients with atrial fibrillation treated with sotalol who developed torsade de pointes due to marked prolongation of the QT interval."7.72A case series of sotalol-induced torsade de pointes in patients with atrial fibrillation--a tale with a twist. ( Chua, T; Hsu, LF; Kam, RM; Tan, HH; Teo, WS, 2003)
"In experimental studies, sotalol has limited class III action in the electrically remodeled atrium and did not prevent atrial fibrillation (AF) induction."7.71Electrophysiologic actions of dl-sotalol in patients with persistent atrial fibrillation. ( Lau, CP; Tse, HF, 2002)
"We sought to determine the yield of in-hospital monitoring for detection of significant arrhythmia complications in patients starting sotalol therapy for atrial arrhythmias and to identify factors that might predict safe outpatient initiation."7.70Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications. ( Chung, MK; Jaeger, FJ; Kidwell, GA; Miller, DP; Morant, VA; Niebauer, MJ; Pinski, SL; Schweikert, RA; Tchou, PJ; Trohman, RG; Wilkoff, BL, 1998)
" She had used sotalol 80 mg once daily for three years without any episodes of proarrhythmia or other adverse effects."7.70T wave alternans after sotalol: evidence for increased sensitivity to sotalol after conversion from atrial fibrillation to sinus rhythm. ( Tan, HL; Wilde, AA, 1998)
"To study the incidence and mode of onset of early reinitiation of atrial fibrillation (ERAF) following successful internal cardioversion of chronic atrial fibrillation, and to determine the effects of sotalol in the prevention of ERAF."7.70Incidence and modes of onset of early reinitiation of atrial fibrillation after successful internal cardioversion, and its prevention by intravenous sotalol. ( Ayers, GM; Lau, CP; Tse, HF, 1999)
"This study was designed to evaluate and compare the effects of oral sotalol for the treatment of vagal and adrenergic paroxysmal atrial fibrillation (PAF)."7.70Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation. ( Aslan, O; Bayata, S; Postaci, N; Yeşil, M; Yücel, O, 1999)
"This study was undertaken to assess the effects of sotalol on the transthoracic cardioversion energy requirement for chronic atrial fibrillation (AF) and on the atrial electrograms during AF recorded by two basket electrodes."7.70Intravenous sotalol decreases transthoracic cardioversion energy requirement for chronic atrial fibrillation in humans: assessment of the electrophysiological effects by biatrial basket electrodes. ( Huang, SK; Lai, LP; Lien, WP; Lin, JL; Tseng, YZ, 2000)
"To investigate the effects of low dose sotalol on the signal averaged surface P wave in patients with paroxysmal atrial fibrillation."7.69Effect of low dose sotalol on the signal averaged P wave in patients with paroxysmal atrial fibrillation. ( Cooper, J; de Bono, DP; Garratt, CJ; Stafford, PJ; Vincent, R, 1995)
"The aim of this study was to evaluate of oral sotalol hydrochloride effects on atrial signal-averaged ECG (ASAECG) during time- and frequency-domain analysis in patients with paroxysmal atrial fibrillation (PAF) during ischemic heart disease (IHD)."7.69[The effect of sotalol hydrochloride therapy on atrial signal-averaged ECG in patients with paroxysmal atrial fibrillation]. ( Banasiak, W; Fuglewicz, A; Kałka, D; Lacheta, W; Pieróg, M; Ponikowski, P; Telichowski, A; Telichowski, C; Wiech, K; Zeborowski, J, 1996)
"A 69 year old woman was treated with sotalol (320 mg daily) for intermittent atrial fibrillation."7.68Sotalol-induced torsade de pointes: management with magnesium infusion. ( Arstall, MA; Hii, JT; Horowitz, JD; Lehman, RG, 1992)
"Dronedarone was associated with a statistically significantly lower risk of all-cause death versus sotalol (hazard ratio [HR] = 0."7.01Dronedarone versus sotalol in patients with atrial fibrillation: A systematic literature review and network meta-analysis. ( Blomström-Lundqvist, C; Camm, AJ; Crotty, C; Fazeli, MS; Kowey, PR; Kreidieh, B; Singh, JP; Turakhia, MP, 2023)
"Sotalol was initiated."6.73Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation. ( Butter, C; Gerhardt, L; Helms, S; Schlegl, M; Stockburger, M, 2007)
"Sotalol is an antiarrhythmic agent with combined beta-blocking and class III antiarrhythmic properties."6.68Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group. ( Das, G; Falk, R; Hanyok, JJ; Hardy, SA; Karagounis, L; Platia, E; Sung, RJ; Tan, HL, 1995)
" If sinus rhythm could not be established at that time, electric cardioversion was performed and the drug was continued in lower dosage thereafter."6.67[Sotalol and quinidine/verapamil (Cordichin) in chronic atrial fibrillation--conversion and 12-month follow-up--a randomized comparison]. ( Betz, P; Kalusche, D; Roskamm, H; Stockinger, J, 1994)
"Sotalol is a beta-adrenergic blocking drug with the additional property of lengthening the cardiac action potential."6.67Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery. ( Dion, R; Evenepoel, M; Evrard, P; Goenen, M; Jacquet, L; Marenne, F; Verhelst, R, 1994)
"Sotalol was effective in reducing the incidence of atrial fibrillation."6.67Oral sotalol reduces the incidence of atrial fibrillation after coronary artery bypass surgery. ( Berggren, H; Edvardsson, N; Nyström, U; Pizzarelli, GP; Rådegran, K, 1993)
"Amiodarone was associated with the highest rate of patients experiencing at least one serious adverse event (OR 2."6.47Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation. ( Eckert, L; Freemantle, N; Lafuente-Lafuente, C; Mitchell, S; Reynolds, M, 2011)
"Both amiodarone and sotalol were more effective than placebo treatment in reducing the incidence of postoperative AFF."6.41Amiodarone vs. sotalol as prophylaxis against atrial fibrillation/flutter after heart surgery: a meta-analysis. ( Lenz, TL; Mohiuddin, SM; Mooss, AN; Wurdeman, RL, 2002)
"This study suggests that flecainide and beta-blockers association is complementary to implantable cardioverter-defibrillator and catheter ablation and is safe for treating persistent symptomatic VA in patients with ARVC."5.72Safety and efficacy of flecainide associated with beta-blockers in arrhythmogenic right ventricular cardiomyopathy. ( Badenco, N; Duthoit, G; Frank, R; Gandjbakhch, E; Hidden-Lucet, F; Himbert, C; Laredo, M; Maupain, C; Rolland, T; Waintraub, X, 2022)
" Sotalol is a nonselective β-adrenergic receptor antagonist with class III antiarrhythmic properties that has been mostly used for atrial fibrillation treatment and suppressing recurrent ventricular tachyarrhythmias."5.41The Arrhythmogenicity of Sotalol and its Role in Heart Failure: A Literature Review. ( Alvarez, C; Augustin, N; Kluger, J, 2023)
"In conclusion, for patients with paroxysmal atrial fibrillation admitted for dofetilide or sotalol loading, T-wave markers of increased repolarization heterogeneity are measurable within hours after initiation."5.40Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation. ( Dorsey, P; Hayes, M; Kaplan, R; Passman, R; Sauer, AJ; Shah, SJ; Xue, J, 2014)
" Adverse events (AEs) associated with AADs may influence patient compliance and compromise the management of atrial fibrillation (AF)."5.37One-year treatment persistence and potential adverse events among patients with atrial fibrillation treated with amiodarone or sotalol: a retrospective claims database analysis. ( Jhaveri, M; Kim, MH; Klingman, D; Lin, J; Smith, PJ, 2011)
"Oral sotalol treatment was started after unsuccessful DC cardioversion and given at least 7 days before renewed cardioversion."5.33Rate of conversion and recurrence after sotalol treatment in patients with direct current-refractory atrial fibrillation. ( Frick, M; Nergärdh, A; Nordlander, R, 2006)
"If the fetal atrial flutter is resistant to these therapies, a combination of other congenital cardiac diseases or organic abnormalities should be considered."5.33Fetal atrial flutter: a case report and experience of sotalol treatment. ( Chiu, TH; Ho, M; Huang, LC; Hung, YC; Lee, CC; Wu, TH, 2006)
" Conversion to sinus rhythm was achieved in 16 out of 22 hemodynamically stable children with a dosage of 4."5.30Sotalol for atrial tachycardias after surgery for congenital heart disease. ( Beaufort-Krol, GC; Bink-Boelkens, MT, 1997)
"Univariate predictors for recurrence included coronary artery disease (p < 0."5.30Patient characteristics and underlying heart disease as predictors of recurrent atrial fibrillation after internal and external cardioversion in patients treated with oral sotalol. ( Alt, E; Ammer, R; Ayers, GM; Lehmann, G; Pasquantonio, J; Pütter, K; Schömig, A, 1997)
"Sotalol is a betablocker with additional antiarrythmic properties."5.30[Sotalol--atrial fibrillation, reduced renal function and sudden death]. ( Bathen, J; Madsen, S, 1998)
"Sotalol has Class II and III antiarrhythmic effects."5.28Atrial fibrillation in Wolff-Parkinson-White syndrome: reversal of isoproterenol effects by sotalol. ( Madrid, AH; Maŕin Huerta, EM; Mestre, JL; Moro, C; Novo, L, 1992)
" Twenty-nine patients with supraventricular tachyarrhythmias were treated on 31 occasions to determine the effective therapeutic dosage and optimal method of administration."5.27Sotalol infusion in the treatment of supraventricular tachyarrhythmias. ( Harte, M; Horgan, JH; Teo, KK, 1985)
" The history of this approach has been disappointing, marked by catastrophic failures such as those of sodium channel blockers or sotalol to treat ventricular arrhythmias in the setting of structural cardiomyopathies, which led to increased mortality, and by modest clinical efficacy in paroxysmal atrial fibrillation."5.22The Future of Antiarrhythmic Drug Therapy: Will Drugs Be Entirely Replaced by Procedures? ( Valderrábano, M, 2022)
"Sotalol is recommended to prevent relapse of atrial fibrillation after cardioversion (CV)."5.22Reduction over time of QTc prolongation in patients with sotalol after cardioversion of atrial fibrillation. ( Darpö, B; Ferber, G; Frick, M; Lenhoff, H; Rosenqvist, M, 2016)
"Sotalol is a commonly prescribed antiarrhythmic drug (AAD) used for maintaining sinus rhythm in patients with atrial fibrillation (AF)."5.19Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease. ( Al-Khatib, SM; Allen-LaPointe, N; Anstrom, KJ; Daubert, JP; DeWald, T; Horton, JR; Lokhnygina, Y; Peterson, ED; Piccini, JP; Shaw, LK; Steinberg, BA; Thomas, K; Wojdyla, DM, 2014)
" The aim of our study was to compare sotalol (S) versus beta-blocking agents (BB) in terms of prevention of ATA, cardioversions (CVs), and cardiovascular hospitalizations (H) in patients paced for bradycardia-tachycardia form of sinus node disease (BT-SND)."5.13The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker. ( Boriani, G; Botto, G; Capucci, A; Favale, S; Marotta, T; Molon, G; Porfilio, A; Proclemer, A; Spampinato, A; Vimercati, M, 2008)
"A total of 55 patients with AF and/or CHF (New York Heart Association functional class > or =III) who had ICDs were divided into 3 groups [amiodarone (n=24), sotalol (n=12), beta-blocker (n=19)] and the cumulative rates of inappropriate shocks were compared."5.13Effects of antiarrhythmic drugs on inappropriate shocks in patients with implantable cardioverter defibrillators. ( Choi, KJ; Kim, HY; Kim, J; Kim, YH; Lee, CH; Nam, GB; Park, HG; Park, KM, 2008)
"To evaluate the effects and adverse reactions of amiodarone and sotalol in treatment of atrial fibrillation."5.12[Effects of amiodarone versus sotalol in treatment of atrial fibrillation: a random controlled clinical study]. ( Chen, YX; Guo, WL; Huang, CX; Jiang, H; Jin, CR; Liu, ZM; Niu, F; Yang, B, 2006)
"To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients with symptomatic persistent atrial fibrillation, adequate anticoagulant therapy, and planned electrical cardioversion."5.12Azimilide vs. placebo and sotalol for persistent atrial fibrillation: the A-COMET-II (Azimilide-CardiOversion MaintEnance Trial-II) trial. ( Borggrefe, M; Lombardi, F; Lüderitz, B; Ruzyllo, W, 2006)
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."5.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
"Patients (n=187) with symptomatic persistent atrial fibrillation at the background of ischemic heart disease after restoration of sinus rhythm were randomized for treatment with sotalol 80 - 160 mg/day (n=48), or with combinations of sotalol with perindopril 4 - 8 mg/day (n=48), rosuvastatin 5 - 20 mg/day (n=45), or omega-3 polyunsaturated fatty acids containing preparation 1 g/day (n=45)."5.12[Influence of perindopril, rosuvastatin, or omega-3 polyunsaturated fatty acids on efficacy of antirecurrence therapy with sotalol in patients with persistent atrial fibrillation]. ( Bodrikova, VV; Kanorskaia, IuS; Kanorskiĭ, SG, 2007)
"Amiodarone and sotalol are commonly used for the maintenance of sinus rhythm, but the efficacy of these agents administered as high-dose infusions for rapid conversion of atrial fibrillation is unknown."5.11Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial. ( Cooper, MJ; Crampton, R; Eipper, V; Guy, D; Kijvanit, P; Ross, DL; Thomas, SP; Wallace, E, 2004)
"Oral low-dose sotalol provides a considerable reduction in the occurrence of atrial fibrillation."5.11Preoperative use of sotalol versus atenolol for atrial fibrillation after cardiac surgery. ( Blasco, M; Carbonell, N; Jordá, A; Martínez-León, J; Núñez, J; Otero, E; Sanjuán, R, 2004)
"Atrial fibrillation (AF) frequently occurs after cardiac surgical procedures, and beta-blockers, sotalol, and amiodarone may reduce the frequency of AF after open heart surgery."5.11A comparison between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: the pilot study of prevention of postoperative atrial fibrillation (SPPAF), a randomized, placebo-controlled trial. ( Auer, J; Berent, R; Eber, B; Hartl, P; Lamm, G; Lassnig, E; Lehner, E; Ng, CK; Puschmann, R; Schwarz, C; Strasser, U; Weber, T, 2004)
"These results show that MgCl(2), in addition to sotalol, is not more effective than sotalol alone in the prevention of tachyarrhythmias after CABG."5.11Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery. ( Beukema, WP; Geertman, H; Sie, HT; van der Starre, PJ; van Rooyen-Butijn, M, 2004)
" We investigated the effects of pretreatment with oral d,l-sotalol on rate-dependent changes in atrial monophasic action potential (MAP) duration after cardioversion of chronic AF with reference to the efficacy in preventing the arrhythmia recurrence."5.11Sotalol reverses remodeled action potential in patients with chronic atrial fibrillation but does not prevent arrhythmia recurrence. ( Ito, A; Kodama, I; Osaka, T; Yamazaki, M; Yokoyama, E, 2004)
"This prospective, randomized, double-blind, placebo-controlled study compared the efficacy and safety of amiodarone and sotalol in the prevention of atrial fibrillation (AF) following open heart surgery."5.11Amiodarone versus sotalol for the treatment of atrial fibrillation after open heart surgery: the Reduction in Postoperative Cardiovascular Arrhythmic Events (REDUCE) trial. ( Arcidi, JM; Hilleman, DE; Lenz, TL; Mohiuddin, SM; Mooss, AN; Packard, KA; Rovang, KS; Sugimoto, JT; Wurdeman, RL, 2004)
"This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation."5.11Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation. ( Chlouverakis, GI; Hamilos, ME; Igoumenidis, NE; Klapsinos, NC; Kochiadakis, GE; Tzerakis, PG; Vardas, PE, 2004)
"Flecainide and sotalol prolong the atrial action potential during atrial fibrillation in humans."5.11Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation. ( Breithardt, G; Eckardt, L; Engelen, M; Franz, MR; Haverkamp, W; Kirchhof, P; Ribbing, M; Wasmer, K, 2005)
"In this double-blind, placebo-controlled trial, we randomly assigned 665 patients who were receiving anticoagulants and had persistent atrial fibrillation to receive amiodarone (267 patients), sotalol (261 patients), or placebo (137 patients) and monitored them for 1 to 4."5.11Amiodarone versus sotalol for atrial fibrillation. ( Atwood, JE; Ezekowitz, MD; Fletcher, RD; Harris, CL; Jacobson, AK; Lewis, HD; Lopez, B; Raisch, DW; Reda, DJ; Sharma, SC; Singh, BN; Singh, SN; Tang, XC, 2005)
"There was a strong trend towards lower mortality associated with the use of class I antiarrhythmic agents or sotalol in managing patients with atrial fibrillation after acute myocardial infarction."5.10Management and outcome of patients with atrial fibrillation during acute myocardial infarction: the GUSTO-III experience. Global use of strategies to open occluded coronary arteries. ( Califf, RM; Criger, DA; Ohman, EM; Topol, EJ; White, HD; Wilcox, RG; Wong, CK, 2002)
"The Sotalol-Amiodarone Fibrillation Efficacy Trial (SAFE-T) is a randomized, double-blind, multicenter, placebo-controlled trial in which the effects of sotalol and amiodarone in maintaining stability of sinus rhythm are being examined in patients with persistent atrial fibrillation at 20 Veterans Affairs medical centers."5.10Comparison of sotalol versus amiodarone in maintaining stability of sinus rhythm in patients with atrial fibrillation (Sotalol-Amiodarone Fibrillation Efficacy Trial [Safe-T]). ( Antman, EM; Atwood, JE; Ezekowitz, MD; Falk, RH; Fletcher, RD; Fye, CL; Jacobson, AK; Lewis, HD; Lopez, B; Reda, DJ; Sharma, SC; Singh, BN; Singh, SN; Tang, XC, 2003)
"In this multicentre randomized controlled trial, 68 patients affected by severely symptomatic paroxysmal atrial fibrillation were assigned, after successful atrioventricular junction ablation and pacing treatment, to antiarrhythmic drug therapy with amiodarone, propafenone, flecainide or sotalol and were compared with 69 patients assigned, after successful AV junction ablation and pacing treatment, to no antiarrhythmic drug therapy."5.10An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation. ( Alboni, P; Bongiorni, MG; Botto, GL; Brignole, M; Bruna, C; Gasparini, M; Menozzi, C; Ometto, R; Verlato, R; Vincenti, A, 2002)
"For patients in whom antiarrhythmic drug therapy is indicated, low dose amiodarone significantly reduces atrial fibrillation-related costs by reducing the number of atrial fibrillation-related procedures."5.10Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial. ( Couturier, A; Dubuc, M; Frasure-Smith, N; Gagné, P; Lambert, J; Lumer, GB; Nattel, S; Roy, D; Talajic, M; Thibault, B, 2002)
"To compare sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation."5.09An open label, randomised, crossover study comparing sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation. ( Birchall, AS; Channer, KS; Smith, M; Steeds, RP, 1999)
"The purpose of this prospective, randomized, double-blind, placebo-controlled study was to assess the efficacy of preoperatively and postoperatively administered oral d,l sotalol in preventing the occurrence of postoperative atrial fibrillation (AF)."5.09Oral d,l sotalol reduces the incidence of postoperative atrial fibrillation in coronary artery bypass surgery patients: a randomized, double-blind, placebo-controlled study. ( Chao, S; Ergin, A; Gomes, JA; Ip, J; Lansman, S; Mehta, D; Newhouse, TT; Pe, E; Santoni-Rugiu, F, 1999)
"Currently d,l-sotalol is widely used to prevent recurrence of atrial fibrillation and/or atrial flutter, although a randomized dose-response study has not previously been conducted to guide therapy for this indication."5.09Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with symptomatic atrial fibrillation and/or atrial flutter. d,l-Sotalol Atrial Fibrillation/Flutter Study Group. ( Benditt, DG; Browne, K; Chang-Sing, P; Deering, TF; Jin, J; Singh, BN; Williams, JH; Zucker, R, 1999)
"To compare the efficacy and safety of sotalol and quinidine after conversion of atrial fibrillation (AF) of <6 months, a prospective multicenter trial enrolled 121 patients who were randomized to receive dl-sotalol (160 to 320 mg/day, 58 patients) or quinidine sulfate (600 to 800 mg/day, 63 patients)."5.09Efficacy and safety of sotalol versus quinidine for the maintenance of sinus rhythm after conversion of atrial fibrillation. SOCESP Investigators. The Cardiology Society of São Paulo. ( de Paola, AA; Veloso, HH, 1999)
"We undertook a prospective, multicenter trial to test the hypothesis that low doses of amiodarone would be more efficacious in preventing recurrent atrial fibrillation than therapy with sotalol or propafenone."5.09Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators. ( Connolly, S; Dorian, P; Dubuc, M; Eisenberg, MJ; Gagné, P; Green, M; Kus, T; Lambert, J; Nattel, S; Roy, D; Talajic, M; Thibault, B, 2000)
"A prospective, randomized controlled trial of new-onset atrial fibrillation was conducted to compare the efficacy and safety of sotalol and amiodarone (active treatment) with rate control by digoxin alone for successful reversion to sinus rhythm at 48 hours."5.09A prospective, randomized controlled trial comparing the efficacy and safety of sotalol, amiodarone, and digoxin for the reversion of new-onset atrial fibrillation. ( Joseph, AP; Ward, MR, 2000)
"In patients with persistent atrial fibrillation, oral treatment with magnesium alone or as an adjuvant to sotalol, does not influence the recurrence rate of atrial fibrillation after elective cardioversion."5.09The effect of oral magnesium, alone or as an adjuvant to sotalol, after cardioversion in patients with persistent atrial fibrillation. ( Darpö, B; Frick, M; Ostergren, J; Rosenqvist, M, 2000)
"To assess and compare the safety and efficacy of amiodarone and sotalol in the treatment of patients with recurrent symptomatic atrial fibrillation."5.09Low dose amiodarone and sotalol in the treatment of recurrent, symptomatic atrial fibrillation: a comparative, placebo controlled study. ( Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Simantirakis, EN; Vardas, PE, 2000)
"This randomized study compared the efficacy and safety of amiodarone, propafenone and sotalol in the prevention of atrial fibrillation."5.09Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm? ( Chrysostomakis, SI; Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Mavrakis, HE; Vardas, PE, 2000)
"To compare the effects of sotalol and metoprolol on heart rate, during isotonic (ITE) and isometric (IME) exercise and daily activities, in digitalized patients with chronic atrial fibrillation."5.09Sotalol vs metoprolol for ventricular rate control in patients with chronic atrial fibrillation who have undergone digitalization: a single-blinded crossover study. ( Igoumenidis, NE; Kalebubas, MD; Kanoupakis, EM; Kochiadakis, GE; Mavrakis, HE; Vardakis, KE; Vardas, PE, 2001)
"The purpose of the study was to compare the efficacy and safety of sotalol and bisoprolol in the maintenance of sinus rhythm after electrical cardioversion of atrial fibrillation."5.09Maintenance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation; sotalol vs bisoprolol. ( Alt, EU; Lehmann, G; Ndrepepa, G; Plewan, A; Schmitt, C; Schömig, A; Schreieck, J, 2001)
"This study was performed to evaluate, using a randomized double-blind, placebo-controlled protocol, the long-term efficacy and safety of propafenone and sotalol in maintaining sinus rhythm after conversion of recurrent symptomatic atrial fibrillation (AF)."5.09Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation. ( Bellandi, F; Dabizzi, RP; Frascarelli, F; Giovannini, T; Leoncini, M; Maioli, M; Simonetti, I, 2001)
"We assessed the efficacy of postoperatively administered oral Sotalol in preventing the occurrence of postoperative atrial fibrillation."5.09Effect of Sotalol in the prevention of atrial fibrillation following coronary artery bypass grafting. ( Ishida, K; Matsuura, K; Sudo, Y; Takahara, Y, 2001)
"This study compared the efficacy and safety of sotalol and quinidine for conversion and prevention of recurrent atrial fibrillation."5.08Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine. ( Baedeker, F; Hohnloser, SH; van de Loo, A, 1995)
"Aim of the present study was to assess the efficacy and safety of flecainide (F) and sotalol (S) for the prevention of recurrences of paroxysmal atrial fibrillation (PAF)."5.08[A comparison between flecainide and sotalol in the prevention of recurrences of paroxysmal atrial fibrillation]. ( Burattini, M; Carunchio, A; Ceci, V; Fera, MS; Galati, A; Greco, G; Mazza, A, 1995)
"We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment."5.08Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995)
"This study determined the effect of sotalol on atrial function after electrical cardioversion of atrial fibrillation."5.08Aggravation of postcardioversion atrial dysfunction by sotalol. ( Falk, RH; Pollak, A, 1995)
"To assess the propafenone and sotalol efficacy in the prevention of paroxysmal atrial fibrillation (FA) we enrolled, in a double blind placebo controlled study over 1 year, 300 patients (168 males); mean age 52."5.08[Propafenone and sotalol: long-term efficacy and tolerability in the prevention of paroxysmal atrial fibrillation. A placebo-controlled double-blind study]. ( Bellandi, F; Cantini, F; Dabizzi, RP; Niccoli, L; Palchetti, R, 1996)
"The main goal of this study is to evaluate the safety and efficacy of propafenone versus sotalol as an initial choice of treatment in patients with symptomatic paroxysmal atrial fibrillation (AF), according to a double-blind randomized system."5.08Comparisons of oral propafenone and sotalol as an initial treatment in patients with symptomatic paroxysmal atrial fibrillation. ( Chang, MS; Chen, SA; Chen, YJ; Cheng, JJ; Chiang, CE; Fong, AN; Huang, JL; Lee, SH; Tai, CT; Wen, ZC; Yu, WC, 1997)
"Sotalol's usefulness in treatment of atrial fibrillation and atrial flutter is unproven."5.08Efficacy and safety of sotalol in patients with refractory atrial fibrillation or flutter. ( Ferrick, KJ; Fisher, JD; Gallik, DM; Kim, SG; Roth, JA, 1997)
"To compare the safety and efficacy of amiodarone and sotalol in the treatment of patients with recurrent symptomatic atrial fibrillation (AF), 70 patients were entered into a randomized, double-blind study."5.08Low-dose amiodarone versus sotalol for suppression of recurrent symptomatic atrial fibrillation. ( Igoumenidis, NE; Kanoupakis, EM; Kochiadakis, GE; Marketou, ME; Solomou, MC; Vardas, PE, 1998)
"To analyze the recurrences of atrial fibrillation in patients treated with sotalol or quinidine."5.08[Analysis of atrial fibrillation recurrence during therapy with sotalol or quinidine. Researchers of +SOCESP]. ( de Paola, AA; Veloso, HH, 1998)
"This study sought to compare the efficacy and safety of intravenous flecainide and sotalol for immediate cardioversion of atrial fibrillation."5.08Prospective comparison of flecainide versus sotalol for immediate cardioversion of atrial fibrillation. ( Ebner, A; Gatterer, E; Gattermeier, M; Heinze, G; Hohenwallner, W; Kratzer, H; Kuhn, P; Lenz, K; Poelzl, G; Reisinger, J; Slany, J; Wiesinger, K; Zeindlhofer, E, 1998)
"Thus, a selective approach based on a clinical risk prediction algorithm should improve the cost-effectiveness and safety of low-dose sotalol in the prevention of atrial fibrillation after coronary bypass surgery."5.08Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification? A prospective placebo-controlled study using low-dose sotalol. ( Buser, P; Huber, M; Osswald, S; Pfisterer, M; Schmidhauser, C; Skarvan, K; Stulz, P; Weber, UK, 1998)
"The purpose of our study (conducted between August 1995 and September 1996) was to evaluate prospectively the efficacy of intravenous administration (in 10 min) of sotalol, flecainide or the combination of these drugs to restore sinus rhythm in patients (without cardiac/pulmonary failure) who came to the First Heart Aid of our hospital with atrial fibrillation lasting less than 24 h."5.08Treatment of recent onset atrial fibrillation with intravenous sotalol and/or flecainide. ( Braat, SH; Heymeriks, J; Peters, FP; Wellens, HJ, 1998)
"To compare the efficacy and safety of a single dose of ibutilide, a new class III antiarrhythmic drug, with that of DL-sotalol in terminating chronic atrial fibrillation or flutter in haemodynamically stable patients."5.08Superiority of ibutilide (a new class III agent) over DL-sotalol in converting atrial flutter and atrial fibrillation. The Ibutilide/Sotalol Comparator Study Group. ( Golitsyn, SR; Harry, JD; Perry, KT; Ruda, MY; Stangl, K; Steinbeck, G; Touboul, P; Van Wijk, LV; Vos, MA; Wellens, HJ, 1998)
"To establish the value of adjuvant dl-sotalol to digoxin for control of the ventricular response in chronic atrial fibrillation, 60 patients were evaluated in a multicenter, randomized, double-blind, parallel, placebo-controlled study."5.07Comparative effects of the combination of digoxin and dl-sotalol therapy versus digoxin monotherapy for control of ventricular response in chronic atrial fibrillation. dl-Sotalol Atrial Fibrillation Study Group. ( Bellinger, R; Brodsky, M; Powers, L; Saini, R; Weiss, R; Zoble, R, 1994)
"This study investigated the hemodynamic effects of oral sotalol during both sinus rhythm and paroxysmal atrial fibrillation."5.07Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation. ( Alboni, P; Chioin, R; Fucà, G; Paparella, N; Pedini, I; Razzolini, R; Scarfò, S, 1993)
"This open, parallel-group study compares quinidine and sotalol treatment for maintenance of sinus rhythm after direct current conversion of patients with chronic atrial fibrillation."5.06Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation. ( Edvardsson, N; Juul-Möller, S; Rehnqvist-Ahlberg, N, 1990)
"The efficacy of sotalol in treating acute atrial fibrillation and flutter after open heart surgery was compared with that of a digoxin/disopyramide combination."5.05Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass. Comparison with disopyramide and digoxin in a randomised trial. ( Campbell, TJ; Gavaghan, TP; Morgan, JJ, 1985)
" β blockers, alone or in combination with digoxin, or non-dihydropyridine calcium-channel blockers (not in heart failure) effectively lower the heart rate."4.93Rate control in atrial fibrillation. ( Crijns, HJ; Olshansky, B; Rienstra, M; Van Gelder, IC, 2016)
"To assess the clinical and cost-effectiveness of magnesium sulphate compared with sotalol, and to assess the clinical effectiveness of magnesium sulphate compared with placebo in the prevention of atrial fibrillation (AF) in patients who have had a coronary artery bypass graft (CABG)."4.84Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation. ( Frampton, GK; Jones, J; Price, A; Shepherd, J; Tanajewski, L; Turner, D, 2008)
" Most recently, the introduction of dofetilide has widened the therapeutic options in patients with severe heart disease, and the Canadian Trial of Atrial Fibrillation indicated the superior efficacy of amiodarone at low doses."4.82Antiarrhythmic drug therapy of atrial fibrillation. ( Mounsey, JP; VerNooy, RA, 2004)
"Many clinicians choose sotalol for the prevention of recurrences of atrial fibrillation (AF) as an alternative to quinidine, which has been associated with an increase in long-term mortality."4.80Comparison of sotalol versus quinidine for maintenance of normal sinus rhythm in patients with chronic atrial fibrillation. ( Bauman, J; Southworth, MR; Viana, M; Zarembski, D, 1999)
"In summary, the Class III antiarrhythmic agents amiodarone and sotalol are effective in restoring sinus rhythm in patients with chronic atrial fibrillation with a higher effectiveness of amiodarone."4.79Indications and limitations of class II and III antiarrhythmic drugs in atrial fibrillation. ( Hohnloser, SH, 1994)
" In patients with successful DC conversion of chronic atrial fibrillation, sotalol proved to be as effective as quinidine in maintaining sinus rhythm but was better tolerated and provided beneficial rate control during atrial fibrillation in those patients who relapsed."4.78Comparison of class I and class III action in atrial fibrillation. ( Edvardsson, N, 1993)
"Among the drugs recommended to prevent recurrences of atrial fibrillation after external electric shock, antiarrhythmic agents of classes Ia (quinidine, disopyramide), Ic (cibenzoline, flecainide, propafenone) and III (sotalol) seem to have the same effectiveness in maintaining the sinus rhythm in about 50 percent of the cases after 6 months and one year."4.78[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock]. ( Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R, 1993)
"Oral sotalol is a class III antiarrhythmic commonly used for the maintenance of sinus rhythm in patients with atrial fibrillation (AF)."4.31Protocol Development and Initial Experience With Intravenous Sotalol Loading for Atrial Arrhythmias. ( Bunch, TJ; Dechand, J; Feuerborn, ML; Freedman, RA; Groh, C; Navaravong, L; Ranjan, R; Steinberg, BA; Torre, M; Vadlamudi, RS; Varela, D, 2023)
"The DASH-AF (Feasibility and Safety of Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients With Atrial Fibrillation) trial evaluates the safety and feasibility of intravenous (IV) sotalol, achieving a steady state with maximum QTc prolongation within 6 hours instead of the traditional 5-dose inpatient oral (PO) titration."4.31Feasibility and Safety of Intravenous Sotalol Loading in Adult Patients With Atrial Fibrillation (DASH-AF). ( Ahmed, A; Atkins, D; Bawa, D; Bommana, S; Bush, J; Charate, R; Darden, D; Garg, J; Gopinathannair, R; Kabra, R; Kennedy, R; Koreber, S; Lakkireddy, D; Mohanty, S; Natale, A; Park, P; Pothineni, NVK; Seo, BW; Tummala, R; Vasamreddy, C, 2023)
"Amiodarone, the most effective antiarrhythmic drug in atrial fibrillation, inhibits apixaban and rivaroxaban elimination, thus possibly increasing anticoagulant-related risk for bleeding."4.31Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study. ( Chung, CP; Daugherty, JR; Dickson, AL; Dupont, WD; Hung, AM; Murray, KT; Ray, WA; Smalley, W; Stein, CM; Zimmerman, E, 2023)
"Sotalol and dronedarone are both used for maintenance of sinus rhythm for patients with atrial fibrillation."4.31Dronedarone Versus Sotalol in Antiarrhythmic Drug-Naive Veterans With Atrial Fibrillation. ( Blomström-Lundqvist, C; Camm, AJ; Din, N; Fan, J; Kabadi, S; Kowey, P; Pundi, K; Rashkin, J; Sandhu, AT; Singh, JP; Turakhia, MP; Wieloch, M, 2023)
"Use of d,l-sotalol for rhythm control in patients with atrial fibrillation (AF) has raised safety concerns."4.31Mortality and ventricular arrhythmias in patients on d,l-sotalol for rhythm control of atrial fibrillation: A nationwide cohort study. ( Darpo, B; Frick, M; Järnbert-Petersson, H; Lenhoff, H; Tornvall, P, 2023)
"There exists variability in the administration of in-patient sotalol therapy for symptomatic atrial fibrillation (AF)."4.12Economics and outcomes of sotalol in-patient dosing approaches in patients with atrial fibrillation. ( B Muhlestein, J; Burnham, TS; Jared Bunch, T; L Anderson, J; L Bair, T; Steinberg, BA; T May, H; U Knowlton, K; Varela, DL, 2022)
" Arrhythmias for which sotalol was initiated included atrioventricular reciprocating tachycardia/atrioventricular nodal reciprocating tachycardia (n = 105 [55%]), atrial flutter (n = 31 [16%]), ectopic atrial tachycardia (n = 26 [14%]), VT (n = 21 [11%]), and atrial fibrillation (n = 7 [4%])."3.96Adverse event rate during inpatient sotalol initiation for the management of supraventricular and ventricular tachycardia in the pediatric and young adult population. ( Abrams, DJ; Alexander, ME; Bevilacqua, LM; Bezzerides, VJ; Chandler, SF; Chu, E; DeWitt, ES; Mah, DY; Triedman, JK; Walsh, EP; Whitehill, RD, 2020)
"We aimed to evaluate the effectiveness and safety of dronedarone versus sotalol in real-world practice in Asian patients with atrial fibrillation (AF)."3.96Comparative clinical outcomes of dronedarone and sotalol in Asian patients with atrial fibrillation: a nationwide cohort study. ( Choi, EK; Kim, JA; Kim, JH; Kwon, TY; Lee, SR; Lee, YE; Oh, S, 2020)
"To evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF)."3.88Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation. ( Broux, B; De Clercq, D; Decloedt, A; Deprez, P; van Loon, G; Van Steenkiste, G; Ven, S; Vera, L, 2018)
"In this clinical setting, we found that thiazides, vessel-active calcium channel blockers, and nonselective beta blockers (specifically sotalol) were associated with a lower risk of incident CHF among patients with atrial fibrillation."3.88Associations between relevant cardiovascular pharmacotherapies and incident heart failure in patients with atrial fibrillation: a cohort study in primary care. ( Ärnlöv, J; Carlsson, AC; Holzmann, MJ; Sundquist, J; Sundquist, K; Wändell, P, 2018)
"Dronedarone was the only anti-arrhythmic drug with significantly lower risk for arrhythmic death, sustained ventricular arrhythmia or ICD implantation than sotalol among patients with atrial fibrillation."3.88Ventricular arrhythmia and death among atrial fibrillation patients using anti-arrhythmic drugs. ( Friberg, L, 2018)
"Our objective was to evaluate the efficacy and safety of intravenous (IV) sotalol in the treatment of incessant tachyarrhythmias in children with normal cardiac function."3.85Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children. ( Ge, H; Jiang, H; Li, X; Liu, H; Zhang, Y, 2017)
"To evaluate the efficacy of sotalol depending on the magnitude of changes in adrenal responsiveness and autonomic nervous system tone in patients with paroxysmal atrial fibrillation (AF)."3.83[A change in adrenal responsiveness in sotalol-treated patients with paroxysmal atrial fibrillation depending on autonomic nervous system tone]. ( Afanasyev, SA; Batalov, RE; Borisova, EV; Kisteneva, IV; Popov, SV; Rebrova, TY, 2016)
"Sotalol and amiodarone are commonly prescribed antiarrhythmics for the treatment of post-operative atrial fibrillation (POAF)."3.83Mortality risk of sotalol and amiodarone for post-CABG atrial fibrillation. ( Brophy, JM; Johnson, SM, 2016)
"To estimate cost-effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation (AF)."3.81Analysis of the cost-effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia. ( Jankovic, SM; Kostic, M; Paunovic, D; Tesic, D, 2015)
"Inpatient antiarrhythmic drug initiation for atrial fibrillation is mandated for dofetilide (DF) and is often performed for sotalol (SL), particularly if proarrhythmia risk factors are present."3.81Risk prediction for adverse events during initiation of sotalol and dofetilide for the treatment of atrial fibrillation. ( Agusala, K; Caprio, T; Kulkarni, C; Oesterle, A; Passman, R; Subacius, H, 2015)
"Retrospective analysis of 2 double-blind, parallel-group trials (EURIDIS [European Trial in Atrial Fibrillation or Flutter Patients Receiving Dronedarone for the Maintenance of Sinus Rhythm] and ADONIS [American-Australian-African Trial With Dronedarone in Atrial Fibrillation or Flutter Patients for the Maintenance of Sinus Rhythm]) comparing the efficacy and safety of dronedarone with placebo over 12 months."3.80Efficacy and safety of dronedarone in patients previously treated with other antiarrhythmic agents. ( Aliot, EM; Capucci, A; Connolly, S; Crijns, HJ; Guerra, F; Hohnloser, SH; Kowey, PR; Radzik, D; Roy, D, 2014)
"Ranolazine is evaluated for antiarrhythmic therapy of atrial fibrillation (AF)."3.79Antiarrhythmic effect of ranolazine in combination with class III drugs in an experimental whole-heart model of atrial fibrillation. ( Breithardt, G; Eckardt, L; Frommeyer, G; Kaese, S; Kaiser, D; Milberg, P; Uphaus, T, 2013)
"In several clinical and pre-clinical studies, application of ranolazine (RAN) led to suppression of atrial fibrillation (AF)."3.79Sodium channel block by ranolazine in an experimental model of stretch-related atrial fibrillation: prolongation of interatrial conduction time and increase in post-repolarization refractoriness. ( Belardinelli, L; Breithardt, G; Eckardt, L; Frommeyer, G; Ghezelbash, S; Milberg, P; Osada, N; Rajamani, S; Razvan, R, 2013)
" dl-Sotalol (SOT) is a β-blocker commonly used in the rhythm-control treatment of atrial fibrillation."3.78Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations. ( Antzelevitch, C; Gibson, JK; Lynch, JJ; Pourrier, M; Sicouri, S, 2012)
"Due to risk of serious adverse drug events (ADEs) sotalol use is limited in renal insufficiency and heart failure."3.77Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement. ( Finks, SW; Manguso, AH; Rogers, KC, 2011)
"An 82-year-old woman with persistent atrial fibrillation underwent successful electrical cardioversion and was begun on sotalol."3.76Sotalol and a broken heart. ( Friedman, PL; Matas, N; Montgomery, S, 2010)
" The aim of this study was to determine the effects of IPC versus intravenous (IV) d,l-sotalol and flecainide infusion on transmural atrial electrophysiology and sustained atrial fibrillation (AF) in the goat."3.75Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation. ( Accord, RE; Allessie, MA; Hermans, JJ; Maessen, JG; Schotten, U; Smits, JF; van Brakel, TJ, 2009)
" The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy."3.75Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009)
"This study evaluated antiarrhythmic effects of d,l-sotalol in a canine atrial fibrillation (AF) model with left ventricular dysfunction."3.75d,l-Sotalol reverses abbreviated atrial refractoriness and prevents promotion of atrial fibrillation in a canine model with left ventricular dysfunction induced by atrial tachypacing. ( Fujiki, A; Hashimoto, N; Inoue, H; Mizumaki, K; Nakatani, Y; Sakabe, M; Sakamoto, T, 2009)
"Sotalol is a class III antiarrhythmic agent that is highly effective for tachyarrhythmias in adults, but its efficacy in patients with congenital heart disease (CHD) remains unclear."3.74Efficacy and safety of sotalol for refractory tachyarrhythmias in congenital heart disease. ( Kamakura, S; Kurosaki, K; Miyazaki, A; Ohuchi, H; Yagihara, T; Yamada, O, 2008)
"Pharmacotherapy of atrial fibrillation has changed towards increased beta-blocker use with a coincident decrease in the use of other rate-limiting drugs and sotalol."3.74Atrial fibrillation pharmacotherapy after hospital discharge between 1995 and 2004: a shift towards beta-blockers. ( Abildstrom, SZ; Folke, F; Friberg, J; Gadsbøll, N; Gislason, GH; Hansen, ML; Køber, L; Madsen, M; Poulsen, HE; Rasmussen, S; Schramm, TK; Sørensen, R; Torp-Pedersen, C, 2008)
" Antiarrhythmic therapy with sotalol at 240 mg/day was started, and after 48 h the patient experienced several episodes of sustained torsade de pointes, dramatic marked QT interval prolongation and negative T wave, in absence of overt cardiac disease, renal failure, electrolyte abnormalities or baseline QT interval prolongation."3.73Sustained torsade de pointes occurring early during oral sotalol therapy for atrial fibrillation recurrence prophylaxis in a patient without heart disease. ( Boldini, A; Brentana, L; D'Aloia, A; Dei Cas, L; Faggiano, P; Pedrinazzi, C; Procopio, R, 2005)
"The combination of sotalol and magnesium can significantly reduce the incidence of post-operative atrial fibrillation following coronary surgery."3.73Does prophylactic sotalol and magnesium decrease the incidence of atrial fibrillation following coronary artery bypass surgery: a propensity-matched analysis. ( Aerra, V; Fabri, BM; Grayson, AD; Kuduvalli, M; Moloto, AN; Oo, AY; Srinivasan, AK, 2006)
"We present 4 patients with atrial fibrillation treated with sotalol who developed torsade de pointes due to marked prolongation of the QT interval."3.72A case series of sotalol-induced torsade de pointes in patients with atrial fibrillation--a tale with a twist. ( Chua, T; Hsu, LF; Kam, RM; Tan, HH; Teo, WS, 2003)
"To determine how well dofetilide and Betapace AF (sotalol, approved solely for atrial fibrillation and atrial flutter), with their detailed dosing and monitoring guidelines for safety, were accepted into clinical practice during the 2 calendar years after their introduction."3.72New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance. ( Kramer, JM; LaPointe, NM; Pamer, CA, 2003)
"To analyze action of digoxin and some non-digitalis drugs (beta-blockers, verapamil, amiodarone, d,l-sotalol) and their combinations on electrical activity of atria, frequency and structure of ventricular rhythm in patients with permanent atrial fibrillation."3.72[Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach]. ( Blagova, OV; Bogdanova, EA; Nedostup, AV; Platonova, AA, 2004)
"In experimental studies, sotalol has limited class III action in the electrically remodeled atrium and did not prevent atrial fibrillation (AF) induction."3.71Electrophysiologic actions of dl-sotalol in patients with persistent atrial fibrillation. ( Lau, CP; Tse, HF, 2002)
"To compare the effects of class Ic and III antiarrhythmic agents on the termination and prevention of atrial fibrillation, the present study investigated the use-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium."3.71Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium. ( Kanmatuse, K; Kojima, T; Kunimoto, S; Masaki, R; Nakai, T; Oshikawa, N; Ozawa, Y; Saito, S; Watanabe, H; Watanabe, I, 2001)
"Clinical trials suggest that sotalol and dofetilide are much more effective in preventing atrial fibrillation (AF) than in terminating it."3.71The class III antiarrhythmic drugs dofetilide and sotalol prevent AF induction by atrial premature complexes at doses that fail to terminate AF. ( Derakhchan, K; Nattel, S; Talajic, M; Villemaire, C, 2001)
"In a 68-year-old woman with severe chronic hepatitis an extensive investigation revealed no other cause than the use of sotalol for 10 months due to atrial fibrillation."3.71[Chronic hepatitis ascribed to the use of sotalol]. ( Janssens, AR; Kootte, AM; Ouwehand, DK; van Leeuwen, AM, 2001)
"We sought to determine the yield of in-hospital monitoring for detection of significant arrhythmia complications in patients starting sotalol therapy for atrial arrhythmias and to identify factors that might predict safe outpatient initiation."3.70Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications. ( Chung, MK; Jaeger, FJ; Kidwell, GA; Miller, DP; Morant, VA; Niebauer, MJ; Pinski, SL; Schweikert, RA; Tchou, PJ; Trohman, RG; Wilkoff, BL, 1998)
" She had used sotalol 80 mg once daily for three years without any episodes of proarrhythmia or other adverse effects."3.70T wave alternans after sotalol: evidence for increased sensitivity to sotalol after conversion from atrial fibrillation to sinus rhythm. ( Tan, HL; Wilde, AA, 1998)
"To study the incidence and mode of onset of early reinitiation of atrial fibrillation (ERAF) following successful internal cardioversion of chronic atrial fibrillation, and to determine the effects of sotalol in the prevention of ERAF."3.70Incidence and modes of onset of early reinitiation of atrial fibrillation after successful internal cardioversion, and its prevention by intravenous sotalol. ( Ayers, GM; Lau, CP; Tse, HF, 1999)
"This study was designed to evaluate and compare the effects of oral sotalol for the treatment of vagal and adrenergic paroxysmal atrial fibrillation (PAF)."3.70Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation. ( Aslan, O; Bayata, S; Postaci, N; Yeşil, M; Yücel, O, 1999)
"This study was undertaken to assess the effects of sotalol on the transthoracic cardioversion energy requirement for chronic atrial fibrillation (AF) and on the atrial electrograms during AF recorded by two basket electrodes."3.70Intravenous sotalol decreases transthoracic cardioversion energy requirement for chronic atrial fibrillation in humans: assessment of the electrophysiological effects by biatrial basket electrodes. ( Huang, SK; Lai, LP; Lien, WP; Lin, JL; Tseng, YZ, 2000)
" 1 and 2, atrial fibrillation was treated with either quinidine or quinidine and sotalol in combination."3.69Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports. ( Faber, TS; Hohnloser, S; Just, H; Van de Loo, A; Zehender, M, 1994)
"To investigate the effects of low dose sotalol on the signal averaged surface P wave in patients with paroxysmal atrial fibrillation."3.69Effect of low dose sotalol on the signal averaged P wave in patients with paroxysmal atrial fibrillation. ( Cooper, J; de Bono, DP; Garratt, CJ; Stafford, PJ; Vincent, R, 1995)
"The aim of this study was to evaluate of oral sotalol hydrochloride effects on atrial signal-averaged ECG (ASAECG) during time- and frequency-domain analysis in patients with paroxysmal atrial fibrillation (PAF) during ischemic heart disease (IHD)."3.69[The effect of sotalol hydrochloride therapy on atrial signal-averaged ECG in patients with paroxysmal atrial fibrillation]. ( Banasiak, W; Fuglewicz, A; Kałka, D; Lacheta, W; Pieróg, M; Ponikowski, P; Telichowski, A; Telichowski, C; Wiech, K; Zeborowski, J, 1996)
"We evaluated the effects of representative class Ia (procainamide), Ic (propafenone), and III (sotalol) antiarrhythmic drugs on sustained cholinergic atrial fibrillation and atrial electrophysiological properties in anesthetized, open-chest dogs."3.68Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness. ( Bourne, GW; Nattel, S; Talajic, M; Villemaire, C; Wang, J; Wang, Z, 1993)
"A 69 year old woman was treated with sotalol (320 mg daily) for intermittent atrial fibrillation."3.68Sotalol-induced torsade de pointes: management with magnesium infusion. ( Arstall, MA; Hii, JT; Horowitz, JD; Lehman, RG, 1992)
"One hundred nine patients with recurrent episodes of symptomatic atrial fibrillation or flutter, or both, who had failed one to five previous antiarrhythmic drug trials were treated with propafenone and, subsequently, sotalol if atrial fibrillation recurred."3.68Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; McGowan, N, 1990)
"The effects of oral Sotalol were assessed by electrophysiological investigations in 6 patients with ventricular preexcitation (Wolff-Parkinson-White syndrome) and a short anterograde refractory period (less than or equal to 280 ms) of the accessory pathway."3.67[Effects of oral sotalol on the conduction of accessory atrioventricular pathways]. ( Blanc, JJ; Boschat, J; Ollivier, JP; Penther, P, 1985)
"Dronedarone was associated with a statistically significantly lower risk of all-cause death versus sotalol (hazard ratio [HR] = 0."3.01Dronedarone versus sotalol in patients with atrial fibrillation: A systematic literature review and network meta-analysis. ( Blomström-Lundqvist, C; Camm, AJ; Crotty, C; Fazeli, MS; Kowey, PR; Kreidieh, B; Singh, JP; Turakhia, MP, 2023)
"Pregnancy is associated with a greater risk of arrhythmias, and patients with a history of arrhythmias are at significant risk of arrhythmia recurrence during pregnancy."2.82Arrhythmias in Pregnancy. ( Briller, JE; Elkayam, U; Lakkireddy, DR; Mason, PK; Merchant, FM; Patel, H; Pillarisetti, J; Russo, AM; Tamirisa, KP; Vaseghi, M; Volgman, AS, 2022)
"Persistent AF and hypertension are independent risk factors for late AF recurrence after pulmonary vein isolation."2.79Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up. ( Balsam, P; Kiliszek, M; Kochanowski, J; Koźluk, E; Lodziński, P; Opolski, G; Piątkowska, A; Piątkowski, R; Scisło, P, 2014)
"Sotalol was superior to placebo in step 4 (OR: 2."2.74Systematic electrocardioversion for atrial fibrillation and role of antiarrhythmic drugs: a substudy of the SAFE-T trial. ( Reda, D; Singh, BN; Singh, SN; Tang, XC, 2009)
"Propafenone was given to Group 1 (G1); sotalol to Group 2 (G2); amiodarone to Group 3 (G3) and diltiazem to Group 4 (G4) at doses of 300 mg/day, 80 mg/day, 400 mg/day and 180 mg/day orally respectively."2.73[The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery]. ( Aytekin, S; Aytekin, V; Men, EE; Tuğcu, A; Yildirimtürk, O, 2008)
" Despite careful precautions, serious proarrhythmias, the major limiting side effect of dofetilide, still occurred during long-term follow-up."2.73Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function. ( Bauman, JL; Kehoe, RF; Leal, S; Mykytsey, A; Razminia, M; Saleem, M; Wang, T; Zheutlin, T, 2007)
"Sotalol was initiated."2.73Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation. ( Butter, C; Gerhardt, L; Helms, S; Schlegl, M; Stockburger, M, 2007)
"Sudden cardiac death was observed in 16 patients, 8 patients in each group."2.72Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study. ( Crijns, HJ; Hagens, VE; Rienstra, M; Van Gelder, IC; Van Veldhuisen, DJ, 2006)
"Amiodarone was more effective at one year than either sotalol or class I agents for the strategy of maintenance of sinus rhythm without cardioversion."2.71Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug. ( , 2003)
"In patients with persistent atrial fibrillation (AF), the efficacy and safety of two anti-arrhythmic drugs in preventing the recurrence of AF after successful direct current (DC) cardioversion was prospectively assessed in a multi-centre double-blind, placebo-controlled, randomised trial using daily trans-telephonic monitoring."2.71Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial. ( Bauer, P; Breithardt, G; Engberding, R; Fetsch, T; Koch, HP; Lukl, J; Meinertz, T; Oeff, M; Seipel, L; Trappe, HJ; Treese, N, 2004)
"Many patients with paroxysmal atrial fibrillation (AF) become refractory to antiarrhythmic drugs (AADs)."2.71Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation. ( Block, JE; Calkins, H; Cher, D; Kocheril, AG; Sharma, AD; Stubbs, HA, 2005)
"However, patients with no symptomatic recurrences of AF had higher scores at 3 months on measures of global well-being than those with recurrences in the first 3 months (7."2.70Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation. ( Connolly, SJ; Dorian, P; Green, M; Newman, D; Paquette, M; Roy, D; Talajic, M, 2002)
"The indication to treat symptomatic paroxysmal atrial fibrillation is discussed controversely."2.69[Medicamentous prevention of symptomatic paroxysmal atrial fibrillation/flutter onset. Goals and design of the SOPAT Study. Executive committee of the investigators representing trial physicians]. ( Koch, HP; Lüderitz, B; Meinertz, T; Patten, M; Sonntag, F, 1999)
"Sotalol is an antiarrhythmic agent with combined beta-blocking and class III antiarrhythmic properties."2.68Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group. ( Das, G; Falk, R; Hanyok, JJ; Hardy, SA; Karagounis, L; Platia, E; Sung, RJ; Tan, HL, 1995)
"In case of PAF recurrence pts withdrew from the study."2.68[Comparison of anti-arrhythmic therapy guided by the transesophageal electropharmacologic test and emperic therapy in the prophylaxis of atrial fibrillation recurrence]. ( Burattini, M; Carunchio, A; Ceci, V; Coletta, C; Fera, MS; Galati, A; Mazza, A, 1997)
" If sinus rhythm could not be established at that time, electric cardioversion was performed and the drug was continued in lower dosage thereafter."2.67[Sotalol and quinidine/verapamil (Cordichin) in chronic atrial fibrillation--conversion and 12-month follow-up--a randomized comparison]. ( Betz, P; Kalusche, D; Roskamm, H; Stockinger, J, 1994)
"Sotalol is a beta-adrenergic blocking drug with the additional property of lengthening the cardiac action potential."2.67Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery. ( Dion, R; Evenepoel, M; Evrard, P; Goenen, M; Jacquet, L; Marenne, F; Verhelst, R, 1994)
"Sotalol was effective in reducing the incidence of atrial fibrillation."2.67Oral sotalol reduces the incidence of atrial fibrillation after coronary artery bypass surgery. ( Berggren, H; Edvardsson, N; Nyström, U; Pizzarelli, GP; Rådegran, K, 1993)
"Amiodarone was associated with the highest rate of patients experiencing at least one serious adverse event (OR 2."2.47Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation. ( Eckert, L; Freemantle, N; Lafuente-Lafuente, C; Mitchell, S; Reynolds, M, 2011)
"Atrial flutter is most often arising from a macroreentry circuit in the right atrium or around scar tissue in case or previous cardiothoracic surgery."2.43[Atrial flutter and fibrillation]. ( Scharf, C, 2005)
"Amiodarone has been demonstrated to be more efficacious than propafenone or sotalol in the Canadian Trial of Atrial Fibrillation."2.42Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. ( Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL, 2003)
"Amiodarone is a highly efficacious antiarrhythmic agent for many cardiac arrhythmias, ranging from atrial fibrillation to malignant ventricular tachyarrhythmias, and seems to be superior to other antiarrhythmic agents."2.42Arrhythmias in the intensive care patient. ( Brandts, B; Trappe, HJ; Weismueller, P, 2003)
" Sotalol requires careful patient selection due to the risk of proarrhythmia and although cardiac effects are rare with amiodarone therapy, potentially serious non-cardiac adverse effects can limit the long-term use of this agent."2.41The role of class III antiarrhythmic agents in maintaining sinus rhythm. ( Brachmann, J, 2000)
"Amiodarone has minimal proarrhythmic risk but has numerous noncardiac toxicities that require frequent monitoring."2.41A review of class III antiarrhythmic agents for atrial fibrillation: maintenance of normal sinus rhythm. ( Cox, CD; Tsikouris, JP, 2001)
"Both amiodarone and sotalol were more effective than placebo treatment in reducing the incidence of postoperative AFF."2.41Amiodarone vs. sotalol as prophylaxis against atrial fibrillation/flutter after heart surgery: a meta-analysis. ( Lenz, TL; Mohiuddin, SM; Mooss, AN; Wurdeman, RL, 2002)
"Sotalol's ability to suppress ventricular ectopy is similar to that of class I agents and better than that of standard beta-blockers."2.40Sotalol: An important new antiarrhythmic. ( Anderson, JL; Prystowsky, EN, 1999)
"Sotalol has a rapid onset of action, allowing it to be efficacious when used orally shortly after surgery."2.40Prevention of atrial fibrillation in the postoperative cardiac patient: significance of oral class III antiarrhythmic agents. ( Morady, F, 1999)
"This study suggests that flecainide and beta-blockers association is complementary to implantable cardioverter-defibrillator and catheter ablation and is safe for treating persistent symptomatic VA in patients with ARVC."1.72Safety and efficacy of flecainide associated with beta-blockers in arrhythmogenic right ventricular cardiomyopathy. ( Badenco, N; Duthoit, G; Frank, R; Gandjbakhch, E; Hidden-Lucet, F; Himbert, C; Laredo, M; Maupain, C; Rolland, T; Waintraub, X, 2022)
"Flecainide was used most frequently (26."1.62Limited duration of antiarrhythmic drug use for newly diagnosed atrial fibrillation in a nationwide population under age 65. ( D'Angelo, RN; Goldstein, L; Kalsekar, I; Khanna, R; Rahman, M; Tung, P; Yadalam, S; Yeh, RW; Zimetbaum, PJ, 2021)
" The objective of this study was to describe prescribing practices of sotalol and dofetilide and to compare safety outcomes between standard and nonstandard dosing strategies."1.56Assessment of Sotalol and Dofetilide Dosing at a Large Academic Medical Center. ( Knowles, D; Malloy, R; Ting, C, 2020)
"Sotalol hydrochloride was a safe anti-arrhythmic drug in the management of this case."1.46Atrial fibrillation management in a breeding stallion. ( Burger, D; Dauvillier, J; Heliczer, N; Lorello, O; Mitchell, K; Navas de Solis, C; Schwarzwald, CC, 2017)
"In this study, we assessed influence of electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits."1.43Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits. ( Chiba, T; Kondo, N; Takahara, A, 2016)
"Dronedarone has failed to make an impact on AAD prescribing."1.43The evolving landscape of oral anti-arrhythmic prescriptions for atrial fibrillation in England: 1998-2014. ( Ahsan, SY; Di Mario, C; Hayward, C; Lyon, AR; Patel, HC; Patel, K; Rowland, E, 2016)
"In conclusion, for patients with paroxysmal atrial fibrillation admitted for dofetilide or sotalol loading, T-wave markers of increased repolarization heterogeneity are measurable within hours after initiation."1.40Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation. ( Dorsey, P; Hayes, M; Kaplan, R; Passman, R; Sauer, AJ; Shah, SJ; Xue, J, 2014)
"Amiodarone was the most widely used active compound (82%) and apparently the most effective."1.39[Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs]. ( Alegret, JM; Freire, F; Romero-Menor, C; Viñolas, X, 2013)
" Adverse events (AEs) associated with AADs may influence patient compliance and compromise the management of atrial fibrillation (AF)."1.37One-year treatment persistence and potential adverse events among patients with atrial fibrillation treated with amiodarone or sotalol: a retrospective claims database analysis. ( Jhaveri, M; Kim, MH; Klingman, D; Lin, J; Smith, PJ, 2011)
" Rhythm control agents are associated with clinically important adverse events."1.36Rhythm control agents and adverse events in patients with atrial fibrillation. ( Hobbs, FD; Hodgkinson, J; Taylor, CJ, 2010)
"Amiodarone or sotalol was used in all postoperative patients for 6 months, except in 8 who had bradycardia."1.33Ablation of atrial fibrillation using microwave energy--early experience. ( Hamzeh, K; Jamil, H; Kabbani, SS; Murad, G; Sabbagh, A, 2005)
"Oral sotalol treatment was started after unsuccessful DC cardioversion and given at least 7 days before renewed cardioversion."1.33Rate of conversion and recurrence after sotalol treatment in patients with direct current-refractory atrial fibrillation. ( Frick, M; Nergärdh, A; Nordlander, R, 2006)
"The current recommended starting dose of sotalol is 80 mg orally twice per day, followed by a judicious increase in dosage every 3 days under continuous telemetry monitoring."1.33Comparison of a standard versus accelerated dosing regimen for D,L-sotalol for the treatment of atrial and ventricular dysrhythmias. ( Gerling, BR; Greenberg, ML; Holzberger, PT; Jones, DR; Juriansz, GJ; Kim, RJ, 2006)
"If the fetal atrial flutter is resistant to these therapies, a combination of other congenital cardiac diseases or organic abnormalities should be considered."1.33Fetal atrial flutter: a case report and experience of sotalol treatment. ( Chiu, TH; Ho, M; Huang, LC; Hung, YC; Lee, CC; Wu, TH, 2006)
"The difference in the time course of AF recurrence in patients with ERAF from those with long AF duration suggests distinct arrhythmogenic mechanisms."1.32Clinical predictors and time course of arrhythmia recurrence in patients with early reinitiation of atrial fibrillation after successful internal cardioversion. ( Lau, CP; Tse, HF, 2003)
" Preprinted order forms or procedural guidelines, as well as computer-assisted dosing programs, can be utilized to prevent inappropriate or miscalculated dosing of these agents, which potentially can cause life-threatening ventricular arrhythmias."1.32Initiation and monitoring of class III antiarrhythmic agents. ( Freeland, S; Worthy, C; Zolnierz, M, 2003)
"The amiodarone was omitted in 17 cases because of its side effects."1.32[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium]. ( Borbély, M; Dani, G; Erdej, F; Hajdara, I; Katona, A; Márk, L; Nagy, E; Sziklai, G, 2004)
"Typical arrhythmias are torsade de pointes occurring during treatment with K(+)-channel inhibitors (e."1.31[Ion channels and arrhythmias]. ( Borchard, U; Hafner, D, 2000)
" The mortality rate in this study was 19% (4 of 21 fetuses; 3 had SVT and 1 had AF); 3 deaths occurred just days after the initiation of sotalol therapy, and 1 occurred after a dosage increase."1.31Sotalol in the treatment of fetal dysrhythmias. ( Kapusta, L; Kleinman, CS; Meijboom, EJ; Michon, MM; Oudijk, MA; Stoutenbeek, P; Visser, GH, 2000)
"The tachyarrhythmias were suppressed by sodium channel blocker, potassium channel blocker or magnesium."1.31Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation. ( Chang, MS; Chen, SA; Chen, YJ; Lin, CI, 2000)
"Average follow up at first AF recurrence was 18."1.31Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters. ( Bacchi Reggiani, L; Bartolotti, M; Biffi, M; Boriani, G; Branzi, A; Zannoli, R, 2002)
"Atrial tachyarrhythmias were induced by right atrial burst pacing."1.30Low energy transvenous cardioversion of short duration atrial tachyarrhythmias in humans using a single lead system. ( Fries, R; Heisel, A; Jung, J; Ozbek, C; Schieffer, H; Sen, S; Stopp, M, 1997)
"Ventricular proarrhythmia is avoided provided that shocks are well synchronized to R waves that are not at closely coupled intervals or preceded by long-short cycles."1.30Initial clinical experience with an implantable human atrial defibrillator. ( Camm, AJ; Ho, DS; Lau, CP; Lee, KL; Lok, NS; Murgatroyd, F; Sopher, M; Tse, HF, 1997)
" Conversion to sinus rhythm was achieved in 16 out of 22 hemodynamically stable children with a dosage of 4."1.30Sotalol for atrial tachycardias after surgery for congenital heart disease. ( Beaufort-Krol, GC; Bink-Boelkens, MT, 1997)
"Univariate predictors for recurrence included coronary artery disease (p < 0."1.30Patient characteristics and underlying heart disease as predictors of recurrent atrial fibrillation after internal and external cardioversion in patients treated with oral sotalol. ( Alt, E; Ammer, R; Ayers, GM; Lehmann, G; Pasquantonio, J; Pütter, K; Schömig, A, 1997)
"Recurrence is common, although antiarrhythmic drugs often effectively decrease the number and duration of recurrent AF episodes."1.30Factors influencing long term persistence of sinus rhythm after a first electrical cardioversion for atrial fibrillation. ( Duytschaever, M; Haerynck, F; Jordaens, L; Tavernier, R, 1998)
"Sotalol is a betablocker with additional antiarrythmic properties."1.30[Sotalol--atrial fibrillation, reduced renal function and sudden death]. ( Bathen, J; Madsen, S, 1998)
"Sotalol may inhibit IK."1.29Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms. ( Hara, Y; Masuda, Y; Mori, K; Nakaya, H; Saito, T, 1995)
"Undersensing of ventricular tachyarrhythmias is a potentially serious problem, as it may lead to failure to deliver therapy."1.29Undersensing during ventricular tachyarrhythmias in a third-generation implantable cardioverter defibrillator: diagnosis using stored electrograms and correction with programming. ( Damle, RS; Kelly, PA; Mann, DE; Reiter, MJ, 1994)
"Sotalol dose was not appropriately adjusted for creatinine clearance which is age and gender dependent."1.29Sotalol proarrhythmia: a report of five cases and an audit of the use of a sotalol in a teaching hospital. ( Basta, MN; Fletcher, PJ; Leitch, JW, 1996)
"Sotalol has Class II and III antiarrhythmic effects."1.28Atrial fibrillation in Wolff-Parkinson-White syndrome: reversal of isoproterenol effects by sotalol. ( Madrid, AH; Maŕin Huerta, EM; Mestre, JL; Moro, C; Novo, L, 1992)
"2% after intravenous d-sotalol, but no adverse symptoms developed."1.28Efficacy, safety, and tolerance of d-sotalol in patients with refractory supraventricular tachyarrhythmias. ( Bigger, JT; Kidwell, GA; Reiffel, JA; Sahar, DI; Squatrito, A, 1989)
" Twenty-nine patients with supraventricular tachyarrhythmias were treated on 31 occasions to determine the effective therapeutic dosage and optimal method of administration."1.27Sotalol infusion in the treatment of supraventricular tachyarrhythmias. ( Harte, M; Horgan, JH; Teo, KK, 1985)

Research

Studies (324)

TimeframeStudies, this research(%)All Research%
pre-199011 (3.40)18.7374
1990's86 (26.54)18.2507
2000's148 (45.68)29.6817
2010's54 (16.67)24.3611
2020's25 (7.72)2.80

Authors

AuthorsStudies
Rolland, T1
Badenco, N1
Maupain, C1
Duthoit, G1
Waintraub, X1
Laredo, M1
Himbert, C1
Frank, R1
Hidden-Lucet, F1
Gandjbakhch, E1
Wetterslev, M1
Møller, MH1
Granholm, A1
Hassager, C1
Haase, N1
Aslam, TN1
Shen, J1
Young, PJ1
Aneman, A1
Hästbacka, J1
Siegemund, M1
Cronhjort, M1
Lindqvist, E1
Myatra, SN1
Kalvit, K1
Arabi, YM1
Szczeklik, W1
Sigurdsson, MI1
Balik, M1
Keus, F1
Perner, A1
Field, ME1
Varela, DL1
Burnham, TS1
T May, H1
L Bair, T1
Steinberg, BA5
B Muhlestein, J1
L Anderson, J1
U Knowlton, K1
Jared Bunch, T1
Tamirisa, KP2
Elkayam, U1
Briller, JE1
Mason, PK1
Pillarisetti, J1
Merchant, FM1
Patel, H1
Lakkireddy, DR1
Russo, AM1
Volgman, AS1
Vaseghi, M1
Wharton, JM1
Piccini, JP5
Koren, A1
Huse, S1
Ronk, CJ2
Udongwo, N1
Desai, D1
Kozlik, A1
Ilagan, J1
Chaughtai, S1
Zacks, ES1
Reynolds, MR1
Bunch, TJ2
Kim, H1
Wieloch, M2
Lip, GYH1
Valderrábano, M1
Feuerborn, ML1
Dechand, J1
Vadlamudi, RS1
Torre, M1
Freedman, RA1
Groh, C1
Navaravong, L1
Ranjan, R1
Varela, D1
Ken-Opurum, J1
Srinivas, SS1
Vadagam, P1
Faith, L1
Park, S1
Charland, S1
Revel, A1
Preblick, R1
Lakkireddy, D1
Ahmed, A1
Atkins, D1
Bawa, D1
Garg, J1
Bush, J1
Charate, R1
Bommana, S1
Pothineni, NVK1
Kabra, R1
Darden, D1
Koreber, S1
Tummala, R1
Vasamreddy, C1
Park, P1
Mohanty, S1
Gopinathannair, R1
Seo, BW1
Natale, A1
Kennedy, R1
Singh, JP2
Blomström-Lundqvist, C2
Turakhia, MP2
Camm, AJ3
Fazeli, MS1
Kreidieh, B1
Crotty, C1
Kowey, PR5
Ray, WA1
Chung, CP1
Stein, CM1
Smalley, W1
Zimmerman, E1
Dupont, WD1
Hung, AM1
Daugherty, JR1
Dickson, AL1
Murray, KT1
Augustin, N1
Alvarez, C1
Kluger, J2
Pundi, K1
Fan, J1
Kabadi, S1
Din, N1
Kowey, P1
Rashkin, J1
Sandhu, AT1
Lenhoff, H3
Järnbert-Petersson, H1
Darpo, B4
Tornvall, P2
Frick, M5
Deering, TF2
Reiffel, JA3
Solomon, AJ1
Ornelas-Loredo, A1
Kany, S1
Abraham, V1
Alzahrani, Z1
Darbar, FA1
Sridhar, A1
Ahmed, M1
Alamar, I1
Menon, A1
Zhang, M1
Chen, Y1
Hong, L1
Konda, S1
Darbar, D1
Chandler, SF1
Chu, E1
Whitehill, RD1
Bevilacqua, LM1
Bezzerides, VJ1
DeWitt, ES1
Alexander, ME1
Abrams, DJ1
Triedman, JK1
Walsh, EP1
Mah, DY1
Ting, C1
Malloy, R1
Knowles, D1
Lee, SR1
Choi, EK1
Kim, JH1
Kim, JA1
Kwon, TY1
Lee, YE1
Oh, S1
Page, A1
Couderc, JP1
D'Angelo, RN1
Rahman, M1
Khanna, R1
Yeh, RW1
Goldstein, L1
Yadalam, S1
Kalsekar, I1
Tung, P1
Zimetbaum, PJ2
Mascarenhas, DAN1
Mudumbi, PC1
Kantharia, BK1
Heliczer, N1
Mitchell, K1
Lorello, O1
Dauvillier, J1
Burger, D1
Schwarzwald, CC1
Navas de Solis, C1
Khan, I1
Patel, HC2
Nanayakkara, S1
Raju, H1
Voskoboinik, A1
Mariani, JA1
Decloedt, A1
Broux, B1
De Clercq, D1
Deprez, P1
Van Steenkiste, G1
Vera, L1
Ven, S1
van Loon, G1
Wu, C1
Tcherny-Lessenot, S1
Dai, W1
Wang, Y1
Kechemir, H1
Gandhi, S1
Lin, S1
Juhaeri, J1
Wändell, P1
Carlsson, AC1
Holzmann, MJ1
Ärnlöv, J1
Sundquist, J1
Sundquist, K1
Friberg, L1
Dobrev, D1
Aguilar, M1
Heijman, J1
Guichard, JB1
Nattel, S10
Chen, JA1
Ptaszek, LM1
Celano, CM1
Beach, SR1
Arsenault, KA1
Yusuf, AM1
Crystal, E4
Healey, JS1
Morillo, CA1
Nair, GM1
Whitlock, RP1
Frommeyer, G2
Milberg, P2
Uphaus, T1
Kaiser, D1
Kaese, S1
Breithardt, G6
Eckardt, L3
Deftereos, S1
Giannopoulos, G1
Kossyvakis, C1
Efremidis, M1
Panagopoulou, V1
Raisakis, K1
Kaoukis, A1
Karageorgiou, S1
Bouras, G1
Katsivas, A1
Pyrgakis, V1
Stefanadis, C1
Thelle, DS1
Selmer, R1
Gjesdal, K1
Sakshaug, S1
Jugessur, A1
Graff-Iversen, S1
Tverdal, A1
Nystad, W1
Zhao, Y1
He, X1
Mathew, JP1
Fullerton, DA1
Hegland, DD1
Hernandez, AF1
Mills, RM1
Klaskala, W1
Peterson, ED3
Lodziński, P1
Kiliszek, M1
Koźluk, E1
Piątkowska, A1
Balsam, P1
Kochanowski, J1
Scisło, P1
Piątkowski, R1
Opolski, G1
Murin, J1
Naditch-Brûlé, L1
Brette, S1
Chiang, CE3
O'Neill, J1
Steg, PG1
Sauer, AJ1
Kaplan, R1
Xue, J1
Dorsey, P1
Hayes, M1
Shah, SJ1
Passman, R2
Al-Khatib, SM2
Wojdyla, DM1
Shaw, LK1
Horton, JR1
Lokhnygina, Y1
Anstrom, KJ1
DeWald, T1
Allen-LaPointe, N1
Thomas, K1
Daubert, JP1
Tesic, D1
Kostic, M1
Paunovic, D1
Jankovic, SM1
Guerra, F1
Hohnloser, SH4
Crijns, HJ5
Aliot, EM1
Radzik, D1
Roy, D7
Connolly, S2
Capucci, A2
Allen LaPointe, NM1
Dai, D1
Thomas, L1
Agusala, K1
Oesterle, A1
Kulkarni, C1
Caprio, T1
Subacius, H1
Qin, D1
Leef, G1
Alam, MB1
Rattan, R1
Munir, MB1
Patel, D1
Khattak, F1
Adelstein, E1
Jain, SK1
Saba, S1
Barrell, EA1
Fiorenza, LR1
Perkins, GA1
Kraus, MS1
Ferber, G1
Rosenqvist, M2
Borisova, EV1
Afanasyev, SA1
Rebrova, TY1
Kisteneva, IV1
Batalov, RE1
Popov, SV1
Chiba, T1
Kondo, N1
Takahara, A1
Johnson, SM1
Brophy, JM1
Hayward, C1
Patel, K1
Di Mario, C1
Lyon, AR1
Ahsan, SY1
Rowland, E1
Van Gelder, IC4
Rienstra, M2
Olshansky, B1
Chouchoulis, K1
Chiladakis, J1
Koutsogiannis, N1
Davlouros, P1
Kaza, M1
Alexopoulos, D1
Li, X1
Zhang, Y2
Liu, H1
Jiang, H2
Ge, H1
Men, EE1
Yildirimtürk, O1
Tuğcu, A1
Aytekin, V1
Aytekin, S1
Shepherd, J1
Jones, J1
Frampton, GK1
Tanajewski, L1
Turner, D1
Price, A1
Botto, G1
Molon, G1
Spampinato, A1
Favale, S1
Proclemer, A1
Porfilio, A1
Marotta, T1
Vimercati, M1
Boriani, G3
Palardy, M1
Ducharme, A1
Tardif, JC1
White, M1
Racine, N1
Tétreault, K1
Dabouz, F1
Talajic, M8
Miyazaki, A1
Ohuchi, H1
Kurosaki, K1
Kamakura, S1
Yagihara, T1
Yamada, O1
van Brakel, TJ1
Hermans, JJ1
Accord, RE1
Schotten, U2
Smits, JF1
Allessie, MA3
Maessen, JG1
Singh, SN8
Tang, XC6
Reda, D1
Singh, BN8
Keivanidou, A1
Arnaoutoglou, C1
Krommydas, A1
Papanikolaou, G1
Tsiptses, K1
Chrisopoulos, C1
Kirpizidis, C1
Kim, MH2
Klingman, D2
Lin, J2
Pathak, P1
Battleman, DS1
Lip, GY3
Watson, T2
Friedman, PL3
Montgomery, S1
Matas, N1
Mihálcz, A1
Földesi, C1
Kardos, A1
Ladunga, K1
Szili-Török, T1
Sakamoto, T1
Fujiki, A1
Nakatani, Y1
Sakabe, M1
Mizumaki, K1
Hashimoto, N1
Inoue, H2
Kapa, S1
Nagel, JJ1
Jahangir, A1
Asirvatham, SJ1
Er, F1
Nia, AM1
Erdmann, E1
Venkataraman, G1
Strickberger, SA1
Camm, J1
Crijns, H1
Dorian, P8
Le Heuzey, JY1
Pedrazzini, L1
Prystowsky, EN2
Salette, G1
Schwartz, PJ1
Torp-Pedersen, C2
Weintraub, W1
Taylor, CJ1
Hodgkinson, J1
Hobbs, FD1
Davis, EM1
Packard, KA2
Hilleman, DE2
Kanorskiĭ, SG2
Kanorskaia, IuS2
Freemantle, N1
Lafuente-Lafuente, C1
Mitchell, S1
Eckert, L1
Reynolds, M1
Kong, DF1
Apostolakis, S1
Finks, SW1
Rogers, KC1
Manguso, AH1
Linz, D1
Neuberger, HR1
Böhm, M1
Wirth, K1
Kerin, NZ1
Jacob, S1
Grunnet, M1
Sicouri, S1
Pourrier, M1
Gibson, JK1
Lynch, JJ1
Antzelevitch, C1
Franz, MR2
Smith, PJ1
Jhaveri, M1
Kumar, S1
Sutherland, F1
Morton, JB1
Lee, G1
Morgan, J1
Wong, J1
Eccleston, DE1
Voukelatos, J1
Garg, ML1
Sparks, PB1
Viñolas, X1
Freire, F1
Romero-Menor, C1
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Clinical Trials (24)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Association of Postoperative Lactate Levels With Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Graft Surgery[NCT05448521]250 participants (Anticipated)Observational2022-08-15Recruiting
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement - a Randomized Controlled Trial[NCT05076019]266 participants (Anticipated)Interventional2022-02-01Recruiting
Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins - Randomized Controlled Trial[NCT05062239]100 participants (Anticipated)Interventional2022-04-01Recruiting
A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery[NCT05780320]242 participants (Anticipated)Observational2022-09-19Active, not recruiting
Pre-Operative Stellate Ganglion to Prevent Post-Operative Atrial Fibrillation[NCT05656170]0 participants (Actual)Interventional2023-10-01Withdrawn (stopped due to Unable to begin study)
Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery[NCT05543278]Phase 4242 participants (Anticipated)Interventional2023-12-01Not yet recruiting
Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation: a Prospective, Controlled, Randomized Pilot Study[NCT02889562]Phase 2/Phase 356 participants (Actual)Interventional2016-09-30Completed
Safety Assessment for Sotalol Protocol in Outpatient Unit[NCT05418036]Phase 4110 participants (Anticipated)Interventional2020-10-26Recruiting
Using Time-dependent Intravenous Infusions of Amiodarone for Conversions to Sinus Rhythms in Patients With Paroxysmal Atrial Fibrillation[NCT03432663]Phase 460 participants (Actual)Interventional2008-08-01Completed
Dual Shock Versus Single Shock Synchronized External Direct Current Cardioversion for Atrial Fibrillation - A Double-blinded Randomized Trial[NCT03943693]Phase 4100 participants (Actual)Interventional2019-04-01Terminated (stopped due to Poor enrollment)
Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150]80 participants (Actual)Observational2007-01-31Completed
[NCT00000556]Phase 30 participants Interventional1995-03-31Completed
Pragmatic Randomized Clinical Trial of Early Dronedarone Versus Usual Care to Change and Improve Outcomes in Persons With First-Detected Atrial Fibrillation[NCT05130268]Phase 43,000 participants (Anticipated)Interventional2021-10-29Active, not recruiting
CSP #399 - The Effects of Antiarrhythmic Therapy in Maintaining Stability of Sinus Rhythm in Atrial Fibrillation[NCT00007605]Phase 3706 participants (Anticipated)Interventional1998-04-30Completed
A Randomized Controlled Trial of Prophylactic Pulmonary Vein Isolation as Adjunct to Coronary Artery Bypass Grafting[NCT00338715]Phase 3193 participants (Actual)Interventional2006-07-31Completed
Reveal® XT Performance Trial[NCT00680927]Phase 4247 participants (Actual)Interventional2007-09-30Completed
First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication[NCT05939076]Phase 3220 participants (Anticipated)Interventional2023-08-21Not yet recruiting
Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation[NCT02145546]Phase 4600 participants (Anticipated)Interventional2014-05-31Not yet recruiting
aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980]500 participants (Anticipated)Observational2015-01-01Recruiting
[NCT00257959]Phase 4400 participants Interventional2001-01-31Completed
A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Treating Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF2) Trial[NCT00340314]Phase 4198 participants Interventional2005-01-31Completed
[NCT00224341]Phase 4360 participants Interventional2003-11-30Recruiting
Subclinical Postoperative Atrial Fibrillation[NCT02522364]150 participants (Anticipated)Interventional2015-08-31Recruiting
Prospective, Randomized Evaluation of New Onset Postoperative Atrial Fibrillation in Subjects Receiving an Amniotic Membrane Patch Placed on the Epicardial Surface[NCT02193321]Phase 1/Phase 20 participants (Actual)Interventional2014-07-31Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Strokes

Efficacy will be measured by the freedom from stroke during the study period. Events relating to stroke will be adjudicated using pre-determined definitions by independent committee members that remain blinded to the patient's treatment arm. (NCT02889562)
Timeframe: 30 days

Interventionparticipants (Number)
Apixaban0
Warfarin0

Number of Participants With Thromboembolytic Events

Efficacy will be measured by the freedom from thromboembolytic events during the study period. Events relating to thromboembolytic events will be adjudicated using pre-determined definitions by independent committee members that remain blinded to the patient's treatment arm. (NCT02889562)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Apixaban0
Warfarin0

Time in Therapeutic Range of INR, if on Warfarin

Time in therapeutic range of INR, if on warfarin, (eg. 2-3), measured as a percentage and defined for each patient using the Rosendaal equation (NCT02889562)
Timeframe: 30 days

Interventionpercentage (Mean)
Warfarin56.8

Total Post-operative Length of Stay

This will be measured from the date/time of the end of the subject's surgery until the date/time of the patient's discharge from the hospital. This will be measured in hours, to the nearest tenth of an hour. (NCT02889562)
Timeframe: 30 days

Interventionhours (Mean)
Apixaban167.5
Warfarin143.1

Units of Blood Given After Initiation of Anticoagulation Medication

Units of blood or blood products given after the first dose of anticoagulation. (NCT02889562)
Timeframe: 30 days

Interventiontotal units of blood (Number)
Apixaban6
Warfarin2

Reviews

53 reviews available for sotalol and Auricular Fibrillation

ArticleYear
Arrhythmias in Pregnancy.
    JACC. Clinical electrophysiology, 2022, Volume: 8, Issue:1

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Flecainide; Humans; Pregnancy; Sotalol; Tachyca

2022
The Future of Antiarrhythmic Drug Therapy: Will Drugs Be Entirely Replaced by Procedures?
    Methodist DeBakey cardiovascular journal, 2022, Volume: 18, Issue:5

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Humans; Sotalol; Tachycardia, Ventri

2022
Dronedarone versus sotalol in patients with atrial fibrillation: A systematic literature review and network meta-analysis.
    Clinical cardiology, 2023, Volume: 46, Issue:6

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Humans; Network Meta-An

2023
The Arrhythmogenicity of Sotalol and its Role in Heart Failure: A Literature Review.
    Journal of cardiovascular pharmacology, 2023, 08-01, Volume: 82, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Heart Failure; Hum

2023
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Postoperative atrial fibrillation: mechanisms, manifestations and management.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calci

2019
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2013
Rate control in atrial fibrillation.
    Lancet (London, England), 2016, Aug-20, Volume: 388, Issue:10046

    Topics: Adrenergic beta-Antagonists; Age Factors; Amiodarone; Anti-Arrhythmia Agents; Atenolol; Atrial Fibri

2016
Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2008, Volume: 12, Issue:28

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Cost-Benefit Analysis; Database

2008
Atrial fibrillation (acute onset).
    BMJ clinical evidence, 2008, May-02, Volume: 2008

    Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Sotalol

2008
Pharmacologic prophylaxis of postoperative atrial fibrillation in patients undergoing cardiac surgery: beyond beta-blockers.
    Pharmacotherapy, 2010, Volume: 30, Issue:7

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Amiodarone; Angiotensin Receptor Antagonists; Angiotens

2010
Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Female; Flecainide; Huma

2011
Atrial fibrillation (acute onset).
    BMJ clinical evidence, 2011, Feb-15, Volume: 2011

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Sotalol

2011
The efficacy of sotalol in preventing postoperative atrial fibrillation: a meta-analysis.
    The American journal of medicine, 2011, Volume: 124, Issue:9

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Drug Therapy, Combination; Electro

2011
New insights into the mechanisms and management of atrial fibrillation.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Oct-29, Volume: 167, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiac Catheterization; Hu

2002
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.
    The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Tria

2003
Meta-analysis of antiarrhythmic therapy in the prevention of postoperative atrial fibrillation and the effect on hospital length of stay, costs, cerebrovascular accidents, and mortality in patients undergoing cardiac surgery.
    The American journal of cardiology, 2003, May-01, Volume: 91, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Cardiac Surgica

2003
Arrhythmias in the intensive care patient.
    Current opinion in critical care, 2003, Volume: 9, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter;

2003
Atrial fibrillation after cardiac surgery: update on the evidence on the available prophylactic interventions.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:2

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2003
Atrial stunning: basics and clinical considerations.
    International journal of cardiology, 2003, Volume: 92, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function; Atrial Functi

2003
Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Cost-Benefit Anal

2003
Facilitating electrical cardioversion of persistant atrial fibrillation by antiarrhythmic drugs: update on clinical trial results.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Humans; Propafenone; Randomized

2003
[Chronic heart failure and atrial fibrilation: aspects of management].
    Kardiologiia, 2003, Volume: 43, Issue:10

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmi

2003
Antiarrhythmic drug therapy of atrial fibrillation.
    Cardiology clinics, 2004, Volume: 22, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Flecainide; Humans; Phenethyl

2004
Atrial fibrillation after cardiac surgery: evidence on prophylactic interventions.
    Expert review of cardiovascular therapy, 2003, Volume: 1, Issue:2

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2003
Pharmacologic strategies for prevention of atrial fibrillation after open heart surgery.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:2

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin II; Anti-Arrhythmia Agents; Atrial Fibrillation

2005
[Atrial flutter and fibrillation].
    Praxis, 2005, Nov-09, Volume: 94, Issue:45

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia

2005
Atrial fibrillation post-cardiac surgery: changing perspectives.
    Current medical research and opinion, 2006, Volume: 22, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Atrial Fibrillation; Cardiac Surgical

2006
Guidelines on the prevention and management of de novo atrial fibrillation after cardiac and thoracic surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 30, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Evidence-Based

2006
[Pharmacological therapy for atrial fibrillation after cardiac surgery].
    Kyobu geka. The Japanese journal of thoracic surgery, 2007, Volume: 60, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anticoagulants; Atrial Fibrillation; Calcium Channel Blocke

2007
Indications and limitations of class II and III antiarrhythmic drugs in atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trial

1994
Comparison of class I and class III action in atrial fibrillation.
    European heart journal, 1993, Volume: 14 Suppl H

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trial

1993
Clinical role of d-sotalol and d,l-sotalol in supraventricular arrhythmias, including pre-excitation.
    European heart journal, 1993, Volume: 14 Suppl H

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Atrial Flutter; Clinical Trials as Topic; Humans;

1993
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
    European heart journal, 1993, Volume: 14 Suppl E

    Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Fle

1993
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock].
    Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; El

1993
[Therapy of atrial fibrillation with class III anti-arrhythmia agents].
    Herz, 1993, Volume: 18, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Heart Atria; Humans; S

1993
Antiarrhythmic drug therapy in the treatment of atrial fibrillation.
    Cardiology clinics, 1996, Volume: 14, Issue:4

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electrop

1996
Risks of initiating therapy with sotalol for treatment of atrial fibrillation.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:1

    Topics: Aged; Ambulatory Care; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flu

1998
Sotalol: An important new antiarrhythmic.
    American heart journal, 1999, Volume: 137, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Defibri

1999
Comparison of sotalol versus quinidine for maintenance of normal sinus rhythm in patients with chronic atrial fibrillation.
    The American journal of cardiology, 1999, Jun-15, Volume: 83, Issue:12

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Humans; Quinidine; Secondary Preventio

1999
Prevention of atrial fibrillation in the postoperative cardiac patient: significance of oral class III antiarrhythmic agents.
    The American journal of cardiology, 1999, Nov-04, Volume: 84, Issue:9A

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as To

1999
Drug choices in the treatment of atrial fibrillation.
    The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Electric Countershock; Hum

2000
Management and prevention of atrial fibrillation after cardiovascular surgery.
    The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial

2000
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy.
    The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A

    Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit An

2000
Post-cardioversion atrial fibrillation: the synthesis of modern concepts?
    European heart journal, 2000, Volume: 21, Issue:14

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Electric Countershock; Hear

2000
The role of class III antiarrhythmic agents in maintaining sinus rhythm.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 1 Suppl C

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart Conduction Syst

2000
Does prophylaxis against atrial fibrillation after cardiac surgery reduce length of stay or hospital costs?
    Pharmacotherapy, 2001, Volume: 21, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Costs and Cost

2001
A review of class III antiarrhythmic agents for atrial fibrillation: maintenance of normal sinus rhythm.
    Pharmacotherapy, 2001, Volume: 21, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Drug Interactions

2001
New antiarrhythmic drugs for the treatment of atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 2002, Volume: 25, Issue:2

    Topics: Aminobenzoates; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds,

2002
Amiodarone vs. sotalol as prophylaxis against atrial fibrillation/flutter after heart surgery: a meta-analysis.
    Chest, 2002, Volume: 121, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Artery Bypas

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Transient atrial mechanical dysfunction (stunning) after cardioversion of atrial fibrillation and flutter.
    American heart journal, 2002, Volume: 144, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Appendage; Atrial Fibrillation; Atrial

2002
Atrial fibrillation. Is there a safe and highly effective pharmacological treatment?
    Circulation, 1990, Volume: 82, Issue:6

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Death, Sudden; Electric Count

1990
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
    Cardiovascular clinics, 1970, Volume: 2, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillatio

1970

Trials

102 trials available for sotalol and Auricular Fibrillation

ArticleYear
Effectiveness of moxonidine to reduce atrial fibrillation burden in hypertensive patients.
    The American journal of cardiology, 2013, Sep-01, Volume: 112, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Convert

2013
Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up.
    Cardiology journal, 2014, Volume: 21, Issue:4

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Chi-Square Distri

2014
Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease.
    The American journal of cardiology, 2014, Sep-01, Volume: 114, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cause of Death; Coronary Artery Disea

2014
Reduction over time of QTc prolongation in patients with sotalol after cardioversion of atrial fibrillation.
    Heart rhythm, 2016, Volume: 13, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Drug; Electric Counte

2016
[The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery].
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2008, Volume: 8, Issue:3

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Proc

2008
The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker.
    American heart journal, 2008, Volume: 156, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Bradycardia; Cardiac Pacing, Artificial; Fem

2008
Absence of protective effect of renin-angiotensin system inhibitors on atrial fibrillation development: insights from the Canadian Trial of Atrial Fibrillation (CTAF).
    The Canadian journal of cardiology, 2008, Volume: 24, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Female; Humans; Male; Middle

2008
Systematic electrocardioversion for atrial fibrillation and role of antiarrhythmic drugs: a substudy of the SAFE-T trial.
    Heart rhythm, 2009, Volume: 6, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribution; Combined Mod

2009
Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey.
    Clinical cardiology, 2010, Volume: 33, Issue:3

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channe

2010
Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion.
    Heart rhythm, 2012, Volume: 9, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribution; Confidence Interva

2012
Management and outcome of patients with atrial fibrillation during acute myocardial infarction: the GUSTO-III experience. Global use of strategies to open occluded coronary arteries.
    Heart (British Cardiac Society), 2002, Volume: 88, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Female; Hospit

2002
Combination of sotalol and magnesium prevents atrial fibrillation after coronary artery bypass grafting.
    The Annals of thoracic surgery, 2002, Volume: 74, Issue:3

    Topics: Aged; Atrial Fibrillation; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administra

2002
Intracardiac low-energy versus transthoracic high-energy direct-current cardioversion of atrial fibrillation: a randomised comparison.
    Cardiology, 2003, Volume: 99, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Creatine Kinase; Electric

2003
Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study.
    Journal of the American College of Cardiology, 2003, May-21, Volume: 41, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Atriove

2003
Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study.
    Journal of the American College of Cardiology, 2003, May-21, Volume: 41, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Atriove

2003
Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study.
    Journal of the American College of Cardiology, 2003, May-21, Volume: 41, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Atriove

2003
Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study.
    Journal of the American College of Cardiology, 2003, May-21, Volume: 41, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Atriove

2003
Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug.
    Journal of the American College of Cardiology, 2003, Jul-02, Volume: 42, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Endpoint Determination; Humans; Sotalol

2003
Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug.
    Journal of the American College of Cardiology, 2003, Jul-02, Volume: 42, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Endpoint Determination; Humans; Sotalol

2003
Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug.
    Journal of the American College of Cardiology, 2003, Jul-02, Volume: 42, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Endpoint Determination; Humans; Sotalol

2003
Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug.
    Journal of the American College of Cardiology, 2003, Jul-02, Volume: 42, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Endpoint Determination; Humans; Sotalol

2003
Comparison of sotalol versus amiodarone in maintaining stability of sinus rhythm in patients with atrial fibrillation (Sotalol-Amiodarone Fibrillation Efficacy Trial [Safe-T]).
    The American journal of cardiology, 2003, Aug-15, Volume: 92, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Female; Heart Ra

2003
Combination therapy for prevention of atrial fibrillation after coronary artery bypass surgery: a randomized trial of sotalol and magnesium.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypa

2003
Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Atrial Fib

2003
Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial.
    American heart journal, 2004, Volume: 147, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Female; Humans; Infusions, I

2004
Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Health Status Indicators; Humans; Propafeno

2003
Preoperative use of sotalol versus atenolol for atrial fibrillation after cardiac surgery.
    The Annals of thoracic surgery, 2004, Volume: 77, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atenolol; Atrial Fi

2004
A comparison between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: the pilot study of prevention of postoperative atrial fibrillation (SPPAF), a randomized, placebo-controlled trial.
    American heart journal, 2004, Volume: 147, Issue:4

    Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgica

2004
Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiopulmonary Bypass; Coronary Artery

2004
Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial.
    European heart journal, 2004, Volume: 25, Issue:16

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blin

2004
Sotalol reverses remodeled action potential in patients with chronic atrial fibrillation but does not prevent arrhythmia recurrence.
    Journal of cardiovascular electrophysiology, 2004, Volume: 15, Issue:8

    Topics: Action Potentials; Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibril

2004
Amiodarone versus sotalol for the treatment of atrial fibrillation after open heart surgery: the Reduction in Postoperative Cardiovascular Arrhythmic Events (REDUCE) trial.
    American heart journal, 2004, Volume: 148, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Coronary

2004
Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 2004, Dec-15, Volume: 94, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Propafenone; P

2004
Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation.
    Basic research in cardiology, 2005, Volume: 100, Issue:2

    Topics: Action Potentials; Adult; Aged; Anti-Arrhythmia Agents; Atrial Appendage; Atrial Fibrillation; Elect

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Double-Blind M

2005
Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2005, Volume: 12, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Combined Modality Therap

2005
Amiodarone versus Sotalol and Propafenone for prevention of immediate recurrence of atrial fibrillation after internal cardioversion: importance of P wave analysis.
    International journal of cardiology, 2006, Jan-13, Volume: 106, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Female; Humans; Male

2006
A randomized trial of prophylactic antiarrhythmic agents (amiodarone and sotalol) in patients with atrial fibrillation for whom direct current cardioversion is planned.
    American heart journal, 2006, Volume: 151, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Electric C

2006
[Effects of amiodarone versus sotalol in treatment of atrial fibrillation: a random controlled clinical study].
    Zhonghua yi xue za zhi, 2006, Jan-10, Volume: 86, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Admini

2006
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
    Circulation, 2006, Jul-11, Volume: 114, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol

2006
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
    Circulation, 2006, Jul-11, Volume: 114, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol

2006
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
    Circulation, 2006, Jul-11, Volume: 114, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol

2006
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
    Circulation, 2006, Jul-11, Volume: 114, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol

2006
Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program Substudy.
    Journal of the American College of Cardiology, 2006, Aug-15, Volume: 48, Issue:4

    Topics: Activities of Daily Living; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Bl

2006
Azimilide vs. placebo and sotalol for persistent atrial fibrillation: the A-COMET-II (Azimilide-CardiOversion MaintEnance Trial-II) trial.
    European heart journal, 2006, Volume: 27, Issue:18

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blin

2006
Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study.
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium

2006
A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Diseases;

2006
Exercise capacity in atrial fibrillation: a substudy of the Sotalol-Amiodarone Atrial Fibrillation Efficacy Trial (SAFE-T).
    American heart journal, 2007, Volume: 153, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Electric Counter

2007
[Effect of bisoprolol and sotalol on clinical status of patients with proximal form of atrial fibrillation and chronic heart failure].
    Kardiologiia, 2007, Volume: 47, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Fibrillation; Bisoprolol; Exercise Test; Female; He

2007
Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.
    Journal of cardiovascular pharmacology and therapeutics, 2007, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut

2007
Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation.
    The American journal of medicine, 2007, Volume: 120, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Female; Humans; Hyper

2007
A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: the Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA
    American heart journal, 2008, Volume: 155, Issue:1

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Atrial Fibrillation;

2008
Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation.
    Herzschrittmachertherapie & Elektrophysiologie, 2007, Volume: 18, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Combined Modality Therapy; Cross-Ove

2007
Effects of antiarrhythmic drugs on inappropriate shocks in patients with implantable cardioverter defibrillators.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Defibril

2008
[Influence of perindopril, rosuvastatin, or omega-3 polyunsaturated fatty acids on efficacy of antirecurrence therapy with sotalol in patients with persistent atrial fibrillation].
    Kardiologiia, 2007, Volume: 47, Issue:12

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-R

2007
[Circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation. Results of the APAF trial].
    Kardiologiia, 2008, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged; Amiodarone; Angina, Unstable; Anti-Arrhythmia Agents; Atrial Fibrillation;

2008
Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine.
    Journal of the American College of Cardiology, 1995, Volume: 26, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Drug Administration Schedul

1995
[A comparison between flecainide and sotalol in the prevention of recurrences of paroxysmal atrial fibrillation].
    Giornale italiano di cardiologia, 1995, Volume: 25, Issue:1

    Topics: Adult; Aged; Atrial Fibrillation; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged;

1995
Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).
    The American journal of cardiology, 1995, Sep-01, Volume: 76, Issue:7

    Topics: Acute Disease; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Female; Heart R

1995
Risk factors for the development of recurrent atrial fibrillation: role of pacing and clinical variables.
    American heart journal, 1995, Volume: 129, Issue:6

    Topics: Atrial Fibrillation; Cardiac Pacing, Artificial; Chronic Disease; Female; Heart Atria; Heart Disease

1995
[Sotalol and quinidine/verapamil (Cordichin) in chronic atrial fibrillation--conversion and 12-month follow-up--a randomized comparison].
    Zeitschrift fur Kardiologie, 1994, Volume: 83 Suppl 5

    Topics: Aged; Atrial Fibrillation; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Adminis

1994
Aggravation of postcardioversion atrial dysfunction by sotalol.
    Journal of the American College of Cardiology, 1995, Mar-01, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Function; Double-Blind Method; Echocardi

1995
Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group.
    American heart journal, 1995, Volume: 129, Issue:4

    Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Dose-Response Relationship,

1995
Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:4

    Topics: Administration, Oral; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Cardia

1994
Oral sotalol reduces the incidence of atrial fibrillation after coronary artery bypass surgery.
    The Thoracic and cardiovascular surgeon, 1993, Volume: 41, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atrial Fibrillation; Ch

1993
Comparative effects of the combination of digoxin and dl-sotalol therapy versus digoxin monotherapy for control of ventricular response in chronic atrial fibrillation. dl-Sotalol Atrial Fibrillation Study Group.
    American heart journal, 1994, Volume: 127, Issue:3

    Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Double-Blind Method; Drug Therapy, Combination; Elect

1994
Hemodynamic effects of oral sotalol during both sinus rhythm and atrial fibrillation.
    Journal of the American College of Cardiology, 1993, Nov-01, Volume: 22, Issue:5

    Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Cardiac Catheterization; Cardiac Pacing, Art

1993
Propafenone versus sotalol for suppression of recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 1993, Mar-01, Volume: 71, Issue:7

    Topics: Aged; Atrial Fibrillation; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Male;

1993
[Propafenone and sotalol: long-term efficacy and tolerability in the prevention of paroxysmal atrial fibrillation. A placebo-controlled double-blind study].
    Giornale italiano di cardiologia, 1996, Volume: 26, Issue:4

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Electrocardiography;

1996
Sotalol prophylaxis and treatment of atrial fibrillation.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:4

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Sotalol

1996
Effect of electrode position on outcome of low-energy intracardiac cardioversion of atrial fibrillation.
    The American journal of cardiology, 1997, Mar-01, Volume: 79, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Catheterizat

1997
Comparisons of oral propafenone and sotalol as an initial treatment in patients with symptomatic paroxysmal atrial fibrillation.
    The American journal of cardiology, 1997, Apr-01, Volume: 79, Issue:7

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Evaluation S

1997
Oxygen uptake kinetics and cardiopulmonary performance in lone atrial fibrillation and the effects of sotalol.
    Chest, 1997, Volume: 111, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Exe

1997
[Comparison of anti-arrhythmic therapy guided by the transesophageal electropharmacologic test and emperic therapy in the prophylaxis of atrial fibrillation recurrence].
    Giornale italiano di cardiologia, 1997, Volume: 27, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Echocardiography, Transesophageal; Female; Flecainide;

1997
Efficacy and safety of sotalol in patients with refractory atrial fibrillation or flutter.
    American heart journal, 1997, Volume: 134, Issue:2 Pt 1

    Topics: Aged; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Female; Hemodynamics; Humans; Male; Midd

1997
Comparison of sotalol and metoprolol in the prevention of atrial fibrillation after coronary artery bypass surgery.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Electrocardiography; Female; He

1998
Low-dose amiodarone versus sotalol for suppression of recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 1998, Apr-15, Volume: 81, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Female; Follow-Up Stud

1998
Effects of antiarrhythmic drugs on variability of ventricular rate and exercise performance in chronic atrial fibrillation complicated with ventricular arrhythmias.
    International journal of cardiology, 1998, Mar-13, Volume: 64, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Pressure; Chi-Square

1998
[Analysis of atrial fibrillation recurrence during therapy with sotalol or quinidine. Researchers of +SOCESP].
    Arquivos brasileiros de cardiologia, 1998, Volume: 70, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Quinidi

1998
Tachycardia-induced change of atrial refractory period in humans: rate dependency and effects of antiarrhythmic drugs.
    Circulation, 1998, Jun-16, Volume: 97, Issue:23

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electroph

1998
Prospective comparison of flecainide versus sotalol for immediate cardioversion of atrial fibrillation.
    The American journal of cardiology, 1998, Jun-15, Volume: 81, Issue:12

    Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Administration Schedule; Female

1998
Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification? A prospective placebo-controlled study using low-dose sotalol.
    European heart journal, 1998, Volume: 19, Issue:5

    Topics: Adult; Aged; Algorithms; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Dose-R

1998
Treatment of recent onset atrial fibrillation with intravenous sotalol and/or flecainide.
    The Netherlands journal of medicine, 1998, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Thera

1998
Superiority of ibutilide (a new class III agent) over DL-sotalol in converting atrial flutter and atrial fibrillation. The Ibutilide/Sotalol Comparator Study Group.
    Heart (British Cardiac Society), 1998, Volume: 79, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Arrhythmia Agents; Arrhythmias, Cardiac;

1998
[Medicamentous prevention of symptomatic paroxysmal atrial fibrillation/flutter onset. Goals and design of the SOPAT Study. Executive committee of the investigators representing trial physicians].
    Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dose-Response Relationship, Drug; Doubl

1999
[Medicamentous prevention after electric cardioversion of chronic atrial fibrillation. Goals and design of the PAFAC Study].
    Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Dis

1999
An open label, randomised, crossover study comparing sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation.
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Atrial Fibrillation; Cross-Over Studies; Drug Administr

1999
Oral d,l sotalol reduces the incidence of postoperative atrial fibrillation in coronary artery bypass surgery patients: a randomized, double-blind, placebo-controlled study.
    Journal of the American College of Cardiology, 1999, Volume: 34, Issue:2

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Dou

1999
Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with symptomatic atrial fibrillation and/or atrial flutter. d,l-Sotalol Atrial Fibrillation/Flutter Study Group.
    The American journal of cardiology, 1999, Aug-01, Volume: 84, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disease-Free Survival; Dose-Response Re

1999
Efficacy and safety of sotalol versus quinidine for the maintenance of sinus rhythm after conversion of atrial fibrillation. SOCESP Investigators. The Cardiology Society of São Paulo.
    The American journal of cardiology, 1999, Nov-01, Volume: 84, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Female; Heart Rate; Human

1999
A simple HPLC-fluorescence method for the measurement of R,S-sotalol in the plasma of patients with life-threatening cardiac arrhythmias.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:2

    Topics: Anti-Arrhythmia Agents; Area Under Curve; Atrial Fibrillation; Chromatography, High Pressure Liquid;

2000
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
    The New England journal of medicine, 2000, Mar-30, Volume: 342, Issue:13

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Female; Humans

2000
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
    The New England journal of medicine, 2000, Mar-30, Volume: 342, Issue:13

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Female; Humans

2000
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
    The New England journal of medicine, 2000, Mar-30, Volume: 342, Issue:13

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Female; Humans

2000
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
    The New England journal of medicine, 2000, Mar-30, Volume: 342, Issue:13

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Female; Humans

2000
A prospective, randomized controlled trial comparing the efficacy and safety of sotalol, amiodarone, and digoxin for the reversion of new-onset atrial fibrillation.
    Annals of emergency medicine, 2000, Volume: 36, Issue:1

    Topics: Aged; Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Digoxin;

2000
The effect of oral magnesium, alone or as an adjuvant to sotalol, after cardioversion in patients with persistent atrial fibrillation.
    European heart journal, 2000, Volume: 21, Issue:14

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; D

2000
Atrial pacing for suppression of early reinitiation of atrial fibrillation after successful internal cardioversion.
    European heart journal, 2000, Volume: 21, Issue:14

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Electric Count

2000
Low dose amiodarone and sotalol in the treatment of recurrent, symptomatic atrial fibrillation: a comparative, placebo controlled study.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:3

    Topics: Aged; Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Dist

2000
Role of gender and personality on quality-of-life impairment in intermittent atrial fibrillation.
    The American journal of cardiology, 2000, Oct-01, Volume: 86, Issue:7

    Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Fem

2000
Is either sotalol or amiodarone more effective than digoxin for converting patients with new-onset atrial fibrillation (AF) to sinus rhythm within 48 hours?
    The Journal of family practice, 2000, Volume: 49, Issue:11

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Humans; Sotalol; Treatment Outcome

2000
Rate-control versus conversion strategy in postoperative atrial fibrillation: a prospective, randomized pilot study.
    American heart journal, 2000, Volume: 140, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Digoxin;

2000
Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm?
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:11 Pt 2

    Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Heart R

2000
Sotalol vs metoprolol for ventricular rate control in patients with chronic atrial fibrillation who have undergone digitalization: a single-blinded crossover study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2001, Volume: 3, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Circadian

2001
Maintenance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation; sotalol vs bisoprolol.
    European heart journal, 2001, Volume: 22, Issue:16

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Electric Count

2001
Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 2001, Sep-15, Volume: 88, Issue:6

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Surviva

2001
Effect of Sotalol in the prevention of atrial fibrillation following coronary artery bypass grafting.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2001, Volume: 49, Issue:10

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Fem

2001
An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.
    European heart journal, 2002, Volume: 23, Issue:11

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Node; Catheter Ablat

2002
Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation.
    American heart journal, 2002, Volume: 143, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Female; Health Status Indicat

2002
Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial.
    European heart journal, 2002, Volume: 23, Issue:13

    Topics: Aged; Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Costs and Cost

2002
[Sotalol in the Wolff-Parkinson-White syndrome: an electrophysiological and clinical study].
    Giornale italiano di cardiologia, 1992, Volume: 22, Issue:6

    Topics: Adult; Atrial Fibrillation; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Fema

1992
Efficacy and safety of sotalol in digitalized patients with chronic atrial fibrillation. The Sotalol Study Group.
    The American journal of cardiology, 1991, Nov-01, Volume: 68, Issue:11

    Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Double-Blind Method; Electrocardiography, Ambulatory;

1991
Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation.
    Circulation, 1990, Volume: 82, Issue:6

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Death, Sudden; Dose-Response Rel

1990
Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass. Comparison with disopyramide and digoxin in a randomised trial.
    British heart journal, 1985, Volume: 54, Issue:1

    Topics: Atrial Fibrillation; Atrial Flutter; Cardiopulmonary Bypass; Clinical Trials as Topic; Digoxin; Diso

1985

Other Studies

169 other studies available for sotalol and Auricular Fibrillation

ArticleYear
Safety and efficacy of flecainide associated with beta-blockers in arrhythmogenic right ventricular cardiomyopathy.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2022, 02-02, Volume: 24, Issue:2

    Topics: Arrhythmogenic Right Ventricular Dysplasia; Atrial Fibrillation; Defibrillators, Implantable; Flecai

2022
Management of acute atrial fibrillation in the intensive care unit: An international survey.
    Acta anaesthesiologica Scandinavica, 2022, Volume: 66, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Intensive Care Units; Sotalol; Surveys and Ques

2022
Intravenous sotalol-A shortcut to success?
    Journal of cardiovascular electrophysiology, 2022, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Sotalol

2022
Economics and outcomes of sotalol in-patient dosing approaches in patients with atrial fibrillation.
    Journal of cardiovascular electrophysiology, 2022, Volume: 33, Issue:3

    Topics: Aftercare; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Male; Medic

2022
Comparative Safety and Effectiveness of Sotalol Versus Dronedarone After Catheter Ablation for Atrial Fibrillation.
    Journal of the American Heart Association, 2022, Volume: 11, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Dronedarone; Humans; Retrospective S

2022
Esophagopericardial Fistula and Pneumopericardium as a Complication of Pulmonary Vein Isolation in a 62-Year-Old Man with Atrial Fibrillation: A Case Report.
    The American journal of case reports, 2022, Jul-13, Volume: 23

    Topics: Atrial Fibrillation; Chest Pain; Fistula; Humans; Male; Middle Aged; Pneumopericardium; Pulmonary Ve

2022
Novel methodology for the evaluation of symptoms reported by patients with newly diagnosed atrial fibrillation: Application of natural language processing to electronic medical records data.
    Journal of cardiovascular electrophysiology, 2023, Volume: 34, Issue:4

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Dizziness; Dronedarone; Dyspnea; Electronic Heal

2023
Protocol Development and Initial Experience With Intravenous Sotalol Loading for Atrial Arrhythmias.
    Critical pathways in cardiology, 2023, 03-01, Volume: 22, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electric Countershock; Female; H

2023
A value-based budget impact model for dronedarone compared with other rhythm control strategies.
    Journal of comparative effectiveness research, 2023, Volume: 12, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Humans; Sotalol

2023
Feasibility and Safety of Intravenous Sotalol Loading in Adult Patients With Atrial Fibrillation (DASH-AF).
    JACC. Clinical electrophysiology, 2023, Volume: 9, Issue:4

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Feasibility Studies; Humans; Prospective Studies

2023
Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study.
    Annals of internal medicine, 2023, Volume: 176, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Dabigatran; Embolism;

2023
Dronedarone Versus Sotalol in Antiarrhythmic Drug-Naive Veterans With Atrial Fibrillation.
    Circulation. Arrhythmia and electrophysiology, 2023, Volume: 16, Issue:8

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Femal

2023
Mortality and ventricular arrhythmias in patients on d,l-sotalol for rhythm control of atrial fibrillation: A nationwide cohort study.
    Heart rhythm, 2023, Volume: 20, Issue:11

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Humans; So

2023
Chapter 5: Guideline Recommendations: Which AAD and for Whom?
    The American journal of cardiology, 2023, Volume: 205 Suppl 1

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Failure; Humans; Sotalol; Stroke Volume; United S

2023
Association Between Obesity-Mediated Atrial Fibrillation and Therapy With Sodium Channel Blocker Antiarrhythmic Drugs.
    JAMA cardiology, 2020, 01-01, Volume: 5, Issue:1

    Topics: Aged; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Diet, High-Fat; Disease Models, Animal;

2020
Adverse event rate during inpatient sotalol initiation for the management of supraventricular and ventricular tachycardia in the pediatric and young adult population.
    Heart rhythm, 2020, Volume: 17, Issue:6

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Child, Preschool; Electrocardiography, Ambulatory; Fema

2020
Assessment of Sotalol and Dofetilide Dosing at a Large Academic Medical Center.
    Journal of cardiovascular pharmacology and therapeutics, 2020, Volume: 25, Issue:5

    Topics: Academic Medical Centers; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Boston; Drug Dosage Cal

2020
Comparative clinical outcomes of dronedarone and sotalol in Asian patients with atrial fibrillation: a nationwide cohort study.
    Scientific reports, 2020, 09-30, Volume: 10, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Asian People; Atrial Fibrillation; Atrial Flutter; Cause of Death; Dro

2020
Diurnal QT analysis in patients with sotalol after cardioversion of atrial fibrillation.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2021, Volume: 26, Issue:4

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Electrocardiography; Humans; Sot

2021
Limited duration of antiarrhythmic drug use for newly diagnosed atrial fibrillation in a nationwide population under age 65.
    Journal of cardiovascular electrophysiology, 2021, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation;

2021
Outpatient Initiation of Sotalol in Patients with Atrial Fibrillation: Utility of Cardiac Implantable Electronic Devices for Therapy Monitoring.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2021, Volume: 21, Issue:6

    Topics: Atrial Fibrillation; Defibrillators, Implantable; Humans; Monitoring, Physiologic; Outpatients; Sota

2021
Atrial fibrillation management in a breeding stallion.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2017, Volume: 19, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Breeding; Electric Countershock; Horse Disease

2017
Trends in outpatient anti-arrhythmic prescriptions for atrial fibrillation and left atrial ablation in Australia: 1997-2016.
    Internal medicine journal, 2018, Volume: 48, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrilla

2018
Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control Studies; Echocardiography, Dopple

2018
Assessing the Risk for Peripheral Neuropathy in Patients Treated With Dronedarone Compared With That in Other Antiarrhythmics.
    Clinical therapeutics, 2018, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Stud

2018
Associations between relevant cardiovascular pharmacotherapies and incident heart failure in patients with atrial fibrillation: a cohort study in primary care.
    Journal of hypertension, 2018, Volume: 36, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atrial Fibrillation; Calcium Channel Blockers;

2018
Ventricular arrhythmia and death among atrial fibrillation patients using anti-arrhythmic drugs.
    American heart journal, 2018, Volume: 205

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cause of Death; Dronedarone; Female; Flecainide;

2018
Case 9-2019: A 62-Year-Old Man with Atrial Fibrillation, Depression, and Worsening Anxiety.
    The New England journal of medicine, 2019, Mar-21, Volume: 380, Issue:12

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Antidepressive Agents; Anxiety Disorders; Aripiprazol

2019
Antiarrhythmic effect of ranolazine in combination with class III drugs in an experimental whole-heart model of atrial fibrillation.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:6

    Topics: Acetanilides; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; D

2013
Resting heart rate and physical activity as risk factors for lone atrial fibrillation: a prospective study of 309,540 men and women.
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:23

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Early Diagnosis; Exercise; Female; Flecainide; H

2013
Comparative effectiveness of pharmacotherapies for prevention of atrial fibrillation following coronary artery bypass surgery.
    The American journal of cardiology, 2013, Oct-01, Volume: 112, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fib

2013
Clinical characteristics, management, and control of permanent vs. nonpermanent atrial fibrillation: insights from the RealiseAF survey.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Dis

2014
Electrocardiographic markers of repolarization heterogeneity during dofetilide or sotalol initiation for paroxysmal atrial fibrillation.
    The American journal of cardiology, 2014, Jun-15, Volume: 113, Issue:12

    Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Diagnosis, Computer-

2014
ECG response: September 23, 2014.
    Circulation, 2014, Sep-23, Volume: 130, Issue:13

    Topics: Aged; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Drug Therapy, Combination; Electr

2014
Analysis of the cost-effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia.
    Kardiologia polska, 2015, Volume: 73, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cost-Benefit Analysis; Disease-Free Surviva

2015
Efficacy and safety of dronedarone in patients previously treated with other antiarrhythmic agents.
    Clinical cardiology, 2014, Volume: 37, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Double-Blind Method; Droned

2014
Antiarrhythmic drug use in patients <65 years with atrial fibrillation and without structural heart disease.
    The American journal of cardiology, 2015, Feb-01, Volume: 115, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Databases, Factual; Droneda

2015
Risk prediction for adverse events during initiation of sotalol and dofetilide for the treatment of atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 2015, Volume: 38, Issue:4

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Comorbidity; Drug-Related Side Effects and Adverse Reac

2015
Comparative effectiveness of antiarrhythmic drugs for rhythm control of atrial fibrillation.
    Journal of cardiology, 2016, Volume: 67, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Dronedarone; Female;

2016
ECG of the Month. Persistent atrial tachycardia after cardioversion in a horse.
    Journal of the American Veterinary Medical Association, 2015, Oct-01, Volume: 247, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Electrocardiography; Ho

2015
[A change in adrenal responsiveness in sotalol-treated patients with paroxysmal atrial fibrillation depending on autonomic nervous system tone].
    Terapevticheskii arkhiv, 2016, Volume: 88, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Autonomic Nervous System; Coronary Disease;

2016
Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits.
    Journal of pharmacological sciences, 2016, Volume: 130, Issue:3

    Topics: Amiodarone; Animals; Anisoles; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Remodeling; Bepri

2016
Mortality risk of sotalol and amiodarone for post-CABG atrial fibrillation.
    International journal of cardiology, 2016, Jul-01, Volume: 214

    Topics: Aged; Aged, 80 and over; Amiodarone; Atrial Fibrillation; Canada; Comorbidity; Coronary Artery Bypas

2016
The evolving landscape of oral anti-arrhythmic prescriptions for atrial fibrillation in England: 1998-2014.
    European heart journal. Cardiovascular pharmacotherapy, 2016, Volume: 2, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Drug Prescriptions; Drug Utili

2016
Impact of QT interval prolongation following antiarrhythmic drug therapy on left ventricular function.
    Future cardiology, 2017, Volume: 13, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Echocardiography; Electrocardiography

2017
Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children.
    The American journal of cardiology, 2017, 05-01, Volume: 119, Issue:9

    Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschool; Dr

2017
Efficacy and safety of sotalol for refractory tachyarrhythmias in congenital heart disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Natriur

2008
Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation.
    Journal of cardiovascular electrophysiology, 2009, Volume: 20, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Stimulation; Electrocardiography; Ele

2009
Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy.
    Cardiology journal, 2009, Volume: 16, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents; Atrial Fibrillation; Ciprofloxacin;

2009
Cost of hospital admission for antiarrhythmic drug initiation in atrial fibrillation.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Health Care Costs; Hospitalization; Human

2009
Sotalol and a broken heart.
    Journal of cardiovascular electrophysiology, 2010, Volume: 21, Issue:2

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Long QT Syndrome; So

2010
[Effectiveness of D,L-sotalol in post-ablative atrial arrhythmias in patients with atrial fibrillation treated with radiofrequency ablation].
    Orvosi hetilap, 2009, Sep-06, Volume: 150, Issue:36

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control Studies; Catheter

2009
d,l-Sotalol reverses abbreviated atrial refractoriness and prevents promotion of atrial fibrillation in a canine model with left ventricular dysfunction induced by atrial tachypacing.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:10

    Topics: Action Potentials; Administration, Oral; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agent

2009
Reversible vestibular dysfunction secondary to sotalol use.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2010, Volume: 27, Issue:1

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Male; Middle Aged; Sotalol; Vestibular Diseases

2010
[79-year-old patient with paroxysmal artial fibrillation and syncope].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:45

    Topics: Aged; Antihypertensive Agents; Atrial Fibrillation; Diagnosis, Differential; Electrocardiography; Hu

2009
Atrial fibrillation degenerates into ventricular fibrillation.
    Journal of the American College of Cardiology, 2010, Mar-09, Volume: 55, Issue:10

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Defibrillators, Impla

2010
Rhythm control agents and adverse events in patients with atrial fibrillation.
    International journal of clinical practice, 2010, Volume: 64, Issue:8

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control Studies; Female;

2010
[Atrial fibrillation in patients with type 2 diabetes mellitus: specific features of development and antirecurrence therapy].
    Kardiologiia, 2010, Volume: 50, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Atrial Fi

2010
Augmenting maintenance of sinus rhythm in the control of atrial fibrillation by antiarrhythmic drug combinations.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4 Suppl

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Dronedarone; Drug Therap

2010
Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Evidence-Based Medicine; Fleca

2011
Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement.
    The International journal of pharmacy practice, 2011, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Dr

2011
Combined blockade of early and late activated atrial potassium currents suppresses atrial fibrillation in a pig model of obstructive apnea.
    Heart rhythm, 2011, Volume: 8, Issue:12

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Male; Models, Animal; Potassium; P

2011
Pharmacological treatment of atrial fibrillation: what does it take?
    Heart rhythm, 2011, Volume: 8, Issue:12

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Male; Potassium Channels, Voltage-

2011
Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations.
    Heart rhythm, 2012, Volume: 9, Issue:3

    Topics: Acetanilides; Action Potentials; Adrenergic beta-Agonists; Animals; Anisoles; Anti-Arrhythmia Agents

2012
Comparative pharmacophysiology of vernakalant, ranolazine, and d-sotalol in canine pulmonary vein sleeve preparations: new flavors or same old taste?
    Heart rhythm, 2012, Volume: 9, Issue:3

    Topics: Acetanilides; Animals; Anisoles; Atrial Fibrillation; Humans; Piperazines; Pulmonary Veins; Pyrrolid

2012
One-year treatment persistence and potential adverse events among patients with atrial fibrillation treated with amiodarone or sotalol: a retrospective claims database analysis.
    Clinical therapeutics, 2011, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Ma

2011
[Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs].
    Medicina clinica, 2013, Apr-20, Volume: 140, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Mass Index; Comorbidity; Diabete

2013
Estimation and prediction of drug therapy on the termination of atrial fibrillation by autoregressive model with exogenous inputs.
    IEEE journal of biomedical and health informatics, 2013, Volume: 17, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Computer Simulation; Female; Heart Conduction

2013
Sodium channel block by ranolazine in an experimental model of stretch-related atrial fibrillation: prolongation of interatrial conduction time and increase in post-repolarization refractoriness.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2013, Volume: 15, Issue:5

    Topics: Acetanilides; Administration, Oral; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Fl

2013
Electrophysiologic actions of dl-sotalol in patients with persistent atrial fibrillation.
    Journal of the American College of Cardiology, 2002, Dec-18, Volume: 40, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Cardiac Pacing, Artificial; Elec

2002
Findings suggest revised atrial fibrillation approach.
    Report on medical guidelines & outcomes research, 2003, Jan-10, Volume: 14, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channe

2003
A case series of sotalol-induced torsade de pointes in patients with atrial fibrillation--a tale with a twist.
    Annals of the Academy of Medicine, Singapore, 2003, Volume: 32, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Middle Aged; Sotalol; Torsades de

2003
Impact of left atrial size reduction on chronic atrial fibrillation in mitral valve surgery.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pac

2003
Clinical predictors and time course of arrhythmia recurrence in patients with early reinitiation of atrial fibrillation after successful internal cardioversion.
    Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:9

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control Studies; Electric Countershock; Fema

2003
New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.
    Pharmacotherapy, 2003, Volume: 23, Issue:10

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Databases, Factual; Drug Prescriptions;

2003
Initiation and monitoring of class III antiarrhythmic agents.
    Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:12 Suppl

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Administration Schedule; Drug Approval; Drug Label

2003
[Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach].
    Kardiologiia, 2004, Volume: 44, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Electrocardi

2004
Atrial fibrillation: rate control often better than rhythm control.
    Prescrire international, 2004, Volume: 13, Issue:70

    Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramid

2004
[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].
    Orvosi hetilap, 2004, May-09, Volume: 145, Issue:19

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrill

2004
[Perspectives and limitations in the treatment of vagus-induced atrial fibrillation. Insights from cellular pharmacology].
    Medizinische Klinik (Munich, Germany : 1983), 2004, Jul-15, Volume: 99, Issue:7

    Topics: Adult; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cells, Cultured; Culture Media; Heart A

2004
Is atrial remodeling a viable target for prevention of atrial fibrillation recurrence?
    Journal of cardiovascular electrophysiology, 2004, Volume: 15, Issue:8

    Topics: Action Potentials; Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibril

2004
Limitations to antiarrhythmic drug use in patients with atrial fibrillation.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Sep-28, Volume: 171, Issue:7

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Contraindications; Female; Fl

2004
[PAFAC Study. Secondary prevention of atrial fibrillation after cardioversion].
    Der Internist, 2005, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therap

2005
Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs.
    Cardiovascular research, 2005, Jul-01, Volume: 67, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Electric Countershock; Electr

2005
Sustained torsade de pointes occurring early during oral sotalol therapy for atrial fibrillation recurrence prophylaxis in a patient without heart disease.
    International journal of cardiology, 2005, Dec-07, Volume: 105, Issue:3

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Middle Aged; Recu

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, Aug-11, Volume: 353, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Quality of Life; Sotalol

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, Aug-11, Volume: 353, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Hum

2005
Amiodarone versus sotalol for atrial fibrillation.
    The New England journal of medicine, 2005, Aug-11, Volume: 353, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Sex Factors; Sotalol;

2005
Ablation of atrial fibrillation using microwave energy--early experience.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Coronary Ar

2005
Proarrhythmias and antiarrhythmias: two sides of the same coin.
    Heart rhythm, 2005, Volume: 2, Issue:9

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2005
Potential proarrhythmic effect of biventricular pacing: fact or myth?
    Heart rhythm, 2005, Volume: 2, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2005
Sotalol and amiodarone versus digoxin for conversion of recent onset atrial fibrillation.
    American heart journal, 2005, Volume: 150, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Humans; Sotalol; Time Factors

2005
Rate of conversion and recurrence after sotalol treatment in patients with direct current-refractory atrial fibrillation.
    Clinical cardiology, 2006, Volume: 29, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control Studies; Electric Countershock; Fema

2006
Inadvertent toxic drug reaction in the management of atrial fibrillation.
    Journal of the Royal Society of Medicine, 2006, Volume: 99, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Digoxin; Drug Interactions; Electrocardiog

2006
[Conversion in sinus rhythm].
    Praxis, 2006, Feb-01, Volume: 95, Issue:5

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Diagnosis, Differential; Dose-Response Relationship, Dr

2006
[Conversion to sinus rhythm].
    Praxis, 2006, Feb-15, Volume: 95, Issue:7

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Diagnosis, Differential; Diarrhea; Electri

2006
Does prophylactic sotalol and magnesium decrease the incidence of atrial fibrillation following coronary artery bypass surgery: a propensity-matched analysis.
    Journal of cardiothoracic surgery, 2006, Mar-03, Volume: 1

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemoprevention; Coronary A

2006
Combined use of 1C and III agents for highly symptomatic, refractory atrial fibrillation.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2006, Volume: 15, Issue:3

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Drug Combinations; Female

2006
Comparison of a standard versus accelerated dosing regimen for D,L-sotalol for the treatment of atrial and ventricular dysrhythmias.
    Pacing and clinical electrophysiology : PACE, 2006, Volume: 29, Issue:11

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; California; Dose-Response R

2006
Fetal atrial flutter: a case report and experience of sotalol treatment.
    Taiwanese journal of obstetrics & gynecology, 2006, Volume: 45, Issue:1

    Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Delivery,

2006
Atrial fibrillation pharmacotherapy after hospital discharge between 1995 and 2004: a shift towards beta-blockers.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2008, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atr

2008
Sotalol-induced delayed ventricular repolarization in man.
    European heart journal, 1980, Volume: 1, Issue:5

    Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrophysiology; Heart; Hear

1980
[Embolic episodes after treatment of atrial fibrillation in a patient with thyrotoxicosis].
    Ugeskrift for laeger, 1995, Jul-17, Volume: 157, Issue:29

    Topics: Anticoagulants; Arterial Occlusive Diseases; Atrial Fibrillation; Embolectomy; Embolism; Humans; Mal

1995
Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms.
    Circulation, 1995, Jun-01, Volume: 91, Issue:11

    Topics: Acetylcholine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutt

1995
Class III antiarrhythmic drug action in experimental atrial fibrillation. Differences in reverse use dependence and effectiveness between d-sotalol and the new antiarrhythmic drug ambasilide.
    Circulation, 1994, Volume: 90, Issue:4

    Topics: Aminobenzoates; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Bridged Bicyc

1994
Sotalol and end-stage renal failure.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:3

    Topics: Aged; Atrial Fibrillation; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Sotalol

1994
Undersensing during ventricular tachyarrhythmias in a third-generation implantable cardioverter defibrillator: diagnosis using stored electrograms and correction with programming.
    Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:9

    Topics: Aged; Atrial Fibrillation; Defibrillators, Implantable; Electrocardiography; Electrophysiology; Equi

1994
Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.
    Clinical cardiology, 1994, Volume: 17, Issue:4

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Dilated; Drug Combinati

1994
Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness.
    Circulation, 1993, Volume: 88, Issue:3

    Topics: Animals; Atrial Fibrillation; Atrial Function; Cardiac Pacing, Artificial; Dogs; Electric Stimulatio

1993
Effect of low dose sotalol on the signal averaged P wave in patients with paroxysmal atrial fibrillation.
    British heart journal, 1995, Volume: 74, Issue:6

    Topics: Adult; Aged; Algorithms; Anti-Arrhythmia Agents; Atrial Fibrillation; Computers; Cross-Over Studies;

1995
Effect of parenteral d-sotalol on transvenous atrial defibrillation threshold in a canine model of atrial fibrillation.
    American heart journal, 1996, Volume: 132, Issue:1 Pt 1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Node; Coronary Vessels; Defib

1996
Sotalol proarrhythmia: a report of five cases and an audit of the use of a sotalol in a teaching hospital.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Hospitals, Teac

1996
Torsades de pointes from terfenadine and sotalol given in combination.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:10

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Interactions; Electrocardiography; Female; H

1996
Low energy transvenous cardioversion of short duration atrial tachyarrhythmias in humans using a single lead system.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:1 Pt 1

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing

1997
Initial clinical experience with an implantable human atrial defibrillator.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:1 Pt 2

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Pacing, Arti

1997
Sotalol for atrial tachycardias after surgery for congenital heart disease.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:8 Pt 2

    Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Bradycardi

1997
[The effect of sotalol hydrochloride therapy on atrial signal-averaged ECG in patients with paroxysmal atrial fibrillation].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1996, Volume: 1, Issue:5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electrocardi

1996
Patient characteristics and underlying heart disease as predictors of recurrent atrial fibrillation after internal and external cardioversion in patients treated with oral sotalol.
    American heart journal, 1997, Volume: 134, Issue:3

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershoc

1997
[Biatrial stimulation in therapy of paroxysmal atrial tachycardia: a case report].
    Zeitschrift fur Kardiologie, 1997, Volume: 86, Issue:7

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function; Combined Modalit

1997
A comparison of transvenous atrial defibrillation of acute and chronic atrial fibrillation and the effect of intravenous sotalol on human atrial defibrillation threshold.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:10 Pt 1

    Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Combined Modality Thera

1997
Leukocytoclastic vasculitis associated with sotalol therapy.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Exanthema; Humans; Male; Skin Diseases, Vascular;

1998
Factors influencing long term persistence of sinus rhythm after a first electrical cardioversion for atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 1998, Volume: 21, Issue:1 Pt 2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electric Countershock; Female; Fol

1998
[Noninvasive monitoring of anti-arrhythmia sotalol therapy by analysis of intracardiac signals].
    Biomedizinische Technik. Biomedical engineering, 1997, Volume: 42 Suppl

    Topics: Aged; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Dogs; Electrocardiograph

1997
Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia

1998
[Sotalol--atrial fibrillation, reduced renal function and sudden death].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1998, Oct-30, Volume: 118, Issue:26

    Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Death, Sudden, Cardiac;

1998
T wave alternans after sotalol: evidence for increased sensitivity to sotalol after conversion from atrial fibrillation to sinus rhythm.
    Heart (British Cardiac Society), 1998, Volume: 80, Issue:3

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Electrocardiography; Female;

1998
Long-term outcome in patients with chronic atrial fibrillation after successful internal cardioversion.
    The American journal of cardiology, 1999, Feb-15, Volume: 83, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Electric Countershoc

1999
Pharmacologic cardioversion of chronic atrial fibrillation in the goat by class IA, IC, and III drugs: a comparison between hydroquinidine, cibenzoline, flecainide, and d-sotalol.
    Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Disease Models, Animal; Elect

1999
Redefining the role of antiarrhythmic drugs.
    The New England journal of medicine, 1999, Jun-17, Volume: 340, Issue:24

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Chemotherapy, Adjuvant; Defibrillators, Implantable; El

1999
Prevention of postoperative atrial fibrillation: what is the best approach?
    Journal of the American College of Cardiology, 1999, Volume: 34, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Humans; Sotalol

1999
Incidence and modes of onset of early reinitiation of atrial fibrillation after successful internal cardioversion, and its prevention by intravenous sotalol.
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrilla

1999
Lack of prevention of heart failure by serial electrical cardioversion in patients with persistent atrial fibrillation.
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Electric Countershock

1999
Cardioversion with sotalol in selected patients with vagally and adrenergically mediated paroxysmal atrial fibrillation.
    Angiology, 1999, Volume: 50, Issue:9

    Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrilla

1999
Intravenous sotalol decreases transthoracic cardioversion energy requirement for chronic atrial fibrillation in humans: assessment of the electrophysiological effects by biatrial basket electrodes.
    Journal of the American College of Cardiology, 2000, Volume: 35, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Thera

2000
[Ion channels and arrhythmias].
    Zeitschrift fur Kardiologie, 2000, Volume: 89 Suppl 3

    Topics: Action Potentials; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atrial Fib

2000
[Paroxysmal atrial fibrillation].
    Deutsche medizinische Wochenschrift (1946), 2000, Apr-20, Volume: 125 Suppl 1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Electric Countershock; F

2000
Sotalol in the treatment of fetal dysrhythmias.
    Circulation, 2000, Jun-13, Volume: 101, Issue:23

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Hydrops Fetalis; Inf

2000
Widening of the excitable gap during pharmacological cardioversion of atrial fibrillation in the goat: effects of cibenzoline, hydroquinidine, flecainide, and d-sotalol.
    Circulation, 2000, Jul-11, Volume: 102, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female

2000
Amiodarone to prevent recurrence of atrial fibrillation.
    The New England journal of medicine, 2000, Aug-24, Volume: 343, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Disease; Humans; Hypertrophy, Left

2000
Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation.
    Cardiovascular research, 2000, Volume: 48, Issue:2

    Topics: Acetylcholine; Action Potentials; Adenosine; Adrenergic beta-Antagonists; Animals; Arrhythmias, Card

2000
Oral d,l-sotalol in atrial fibrillation and/or flutter.
    The American journal of cardiology, 2000, Jan-01, Volume: 85, Issue:1

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation

2000
Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium.
    Japanese circulation journal, 2001, Volume: 65, Issue:1

    Topics: Action Potentials; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Func

2001
The frequency analysis of signal-averaged ECG of P wave as predictor of efficacy of class III antiarrhythmic drugs to maintain sinus rhythm in recurrent idiopathic atrial fibrillation.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2001, Volume: 6, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Humans;

2001
The class III antiarrhythmic drugs dofetilide and sotalol prevent AF induction by atrial premature complexes at doses that fail to terminate AF.
    Cardiovascular research, 2001, Volume: 50, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Premature Complexes; Dogs; Drug Adminis

2001
Comparison of class III antiarrhythmic drugs versus digoxin for the reversion of new-onset atrial fibrillation.
    Annals of emergency medicine, 2001, Volume: 37, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Humans; Sotalol; Time Factors; Tre

2001
Oral amiodarone and atrial fibrillation.
    Lancet (London, England), 2001, Jul-14, Volume: 358, Issue:9276

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibril

2001
Sotalol: a fool's deal?
    European heart journal, 2001, Volume: 22, Issue:16

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cohort Studies; Humans; Sotalol

2001
Effects of oral sotalol administration before electrical cardioversion of persistent atrial fibrillation.
    European heart journal, 2001, Volume: 22, Issue:16

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Humans; Ma

2001
Global distribution of atrial ectopic foci triggering recurrence of atrial tachyarrhythmia after electrical cardioversion of long-standing atrial fibrillation: a bi-atrial basket mapping study.
    Journal of the American College of Cardiology, 2001, Mar-01, Volume: 37, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock;

2001
[Chronic hepatitis ascribed to the use of sotalol].
    Nederlands tijdschrift voor geneeskunde, 2001, Dec-01, Volume: 145, Issue:48

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Biopsy; Chemical and

2001
[Atrial fibrillation successfully converted. A new standard in the prevention of recurrence?].
    MMW Fortschritte der Medizin, 2001, Dec-13, Volume: 143, Issue:51-52

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Calcium Ch

2001
Maintainance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation.
    European heart journal, 2002, Volume: 23, Issue:7

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Electric Countershock; Humans; Sotalol

2002
Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters.
    Heart (British Cardiac Society), 2002, Volume: 87, Issue:5

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Electro

2002
Suppression of atrial fibrillation by multisite and septal pacing in a novel experimental model.
    Cardiovascular research, 2002, Volume: 54, Issue:2

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atrial Fibrillation; Cardiac Pacing, Art

2002
Amiodarone: pearl or peril?
    European heart journal, 2002, Volume: 23, Issue:13

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cost-Benefit Analysis; Humans; Propafenone;

2002
Atrial fibrillation in Wolff-Parkinson-White syndrome: reversal of isoproterenol effects by sotalol.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Adult; Atrial Fibrillation; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Conductio

1992
Sotalol-induced torsade de pointes: management with magnesium infusion.
    Postgraduate medical journal, 1992, Volume: 68, Issue:798

    Topics: Aged; Amiodarone; Atrial Fibrillation; Dose-Response Relationship, Drug; Electrocardiography, Ambula

1992
Treatment of atrial fibrillation: time for change?
    The Medical journal of Australia, 1992, Jul-20, Volume: 157, Issue:2

    Topics: Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Digitalis Glycosides; Digoxin; Humans;

1992
Serial antiarrhythmic drug treatment to maintain sinus rhythm after electrical cardioversion for chronic atrial fibrillation or atrial flutter.
    The American journal of cardiology, 1991, Aug-01, Volume: 68, Issue:4

    Topics: Actuarial Analysis; Aged; Amiodarone; Analysis of Variance; Atrial Fibrillation; Atrial Flutter; Chr

1991
Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs.
    Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3

    Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Data Interpretation, Statistical; Drug Administrat

1990
New hope in atrial fibrillation.
    Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Quinidine; Sotalol

1990
Efficacy, safety, and tolerance of d-sotalol in patients with refractory supraventricular tachyarrhythmias.
    American heart journal, 1989, Volume: 117, Issue:3

    Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Female;

1989
Sudden death in hemochromatosis after closed-chest catheter ablation of the atrioventricular junction.
    The American journal of cardiology, 1988, Apr-15, Volume: 61, Issue:11

    Topics: Atrial Fibrillation; Atrioventricular Node; Death, Sudden; Electric Countershock; Electrocardiograph

1988
Differential effect of some antiarrhythmic drugs in right- or left-sided aconitine-induced experimental atrial arrhythmias.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:2

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dogs; Female; Male;

1987
Successful termination of combined rapid atrial flutter/fibrillation and ventricular tachycardia by intravenous sotalol.
    Postgraduate medical journal, 1987, Volume: 63, Issue:741

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Humans; Infusions

1987
Protection against ventricular and atrial fibrillation by sotalol.
    Cardiovascular research, 1986, Volume: 20, Issue:5

    Topics: Action Potentials; Animals; Atrial Fibrillation; Cardiopulmonary Bypass; Dogs; Heart; Sotalol; Ventr

1986
[Effects of oral sotalol on the conduction of accessory atrioventricular pathways].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78, Issue:7

    Topics: Administration, Oral; Adult; Atrial Fibrillation; Electrocardiography; Female; Heart Conduction Syst

1985
Sotalol infusion in the treatment of supraventricular tachyarrhythmias.
    Chest, 1985, Volume: 87, Issue:1

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Female; Humans; Male; Middle

1985
Effect of Sotalol on clinical arrhythmias.
    The American journal of cardiology, 1972, Volume: 29, Issue:3

    Topics: Administration, Oral; Aged; Amino Alcohols; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutte

1972