Page last updated: 2024-11-04

sotalol and Apoplexy

sotalol has been researched along with Apoplexy in 5 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone, the most effective antiarrhythmic drug in atrial fibrillation, inhibits apixaban and rivaroxaban elimination, thus possibly increasing anticoagulant-related risk for bleeding."8.31Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study. ( Chung, CP; Daugherty, JR; Dickson, AL; Dupont, WD; Hung, AM; Murray, KT; Ray, WA; Smalley, W; Stein, CM; Zimmerman, E, 2023)
"Amiodarone, the most effective antiarrhythmic drug in atrial fibrillation, inhibits apixaban and rivaroxaban elimination, thus possibly increasing anticoagulant-related risk for bleeding."4.31Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study. ( Chung, CP; Daugherty, JR; Dickson, AL; Dupont, WD; Hung, AM; Murray, KT; Ray, WA; Smalley, W; Stein, CM; Zimmerman, E, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ray, WA1
Chung, CP1
Stein, CM1
Smalley, W1
Zimmerman, E1
Dupont, WD1
Hung, AM1
Daugherty, JR1
Dickson, AL1
Murray, KT1
Qin, D1
Leef, G1
Alam, MB1
Rattan, R1
Munir, MB1
Patel, D1
Khattak, F1
Adelstein, E1
Jain, SK1
Saba, S1
Chauveau, S1
Derex, L1
Chevalier, P1
Zimmer, J1
Pezzullo, J1
Choucair, W1
Southard, J1
Kokkinos, P1
Karasik, P1
Greenberg, MD1
Singh, SN1
Crystal, E1
Connolly, SJ1
Sleik, K1
Ginger, TJ1
Yusuf, S1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pre-Operative Stellate Ganglion to Prevent Post-Operative Atrial Fibrillation[NCT05656170]0 participants (Actual)Interventional2023-10-01Withdrawn (stopped due to Unable to begin study)
A Randomized Controlled Trial of Prophylactic Pulmonary Vein Isolation as Adjunct to Coronary Artery Bypass Grafting[NCT00338715]Phase 3193 participants (Actual)Interventional2006-07-31Completed
Prospective, Randomized Evaluation of New Onset Postoperative Atrial Fibrillation in Subjects Receiving an Amniotic Membrane Patch Placed on the Epicardial Surface[NCT02193321]Phase 1/Phase 20 participants (Actual)Interventional2014-07-31Withdrawn
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement - a Randomized Controlled Trial[NCT05076019]266 participants (Anticipated)Interventional2022-02-01Recruiting
Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins - Randomized Controlled Trial[NCT05062239]100 participants (Anticipated)Interventional2022-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for sotalol and Apoplexy

ArticleYear
Meta-analysis of antiarrhythmic therapy in the prevention of postoperative atrial fibrillation and the effect on hospital length of stay, costs, cerebrovascular accidents, and mortality in patients undergoing cardiac surgery.
    The American journal of cardiology, 2003, May-01, Volume: 91, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Cardiac Surgica

2003
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002
Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing

2002

Other Studies

3 other studies available for sotalol and Apoplexy

ArticleYear
Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study.
    Annals of internal medicine, 2023, Volume: 176, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Dabigatran; Embolism;

2023
Comparative effectiveness of antiarrhythmic drugs for rhythm control of atrial fibrillation.
    Journal of cardiology, 2016, Volume: 67, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Dronedarone; Female;

2016
A heartless brain.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2013, Volume: 15, Issue:6

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Female; Humans; Long QT Syndrome; Sotalol; Stroke; Torsad

2013