sotalol has been researched along with Anesthesia in 13 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared dl-sotalol-induced electrocardiographic responses in intact dogs using a repeated-measures design among 1% halothane anesthesia, 1." | 8.02 | In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state. ( Akie, Y; Goto, A; Hagiwara-Nagasawa, M; Hoshiai, K; Izumi-Nakaseko, H; Kambayashi, R; Kawai, S; Matsumoto, A; Nunoi, Y; Saito, H; Sugiyama, A; Takei, Y, 2021) |
| " and the ventricular fibrillation threshold at doses between 3-100 micrograms/kg and was 80-1000 times more potent than sematilide, racemic sotalol, d-sotalol or quinidine." | 3.68 | Electropharmacology of dofetilide, a new class III agent, in anaesthetised dogs. ( Blackburn, KJ; Burges, RA; Gwilt, M; Higgins, AJ; Milne, AA; Solca, AM, 1992) |
| "Experimental induction of pulmonary emphysema caused an increase in sensitivity of the rat to toxicity from inhalation of propellants." | 1.25 | Toxicity of aerosol propellants in the respiratory and circulatory systems. VII. Influence of pulmonary emphysema and anesthesia in the rat. ( Aviado, DM; Watanabe, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Saito, H | 2 |
| Kambayashi, R | 1 |
| Hagiwara-Nagasawa, M | 1 |
| Nunoi, Y | 1 |
| Goto, A | 1 |
| Izumi-Nakaseko, H | 2 |
| Kawai, S | 1 |
| Takei, Y | 1 |
| Matsumoto, A | 1 |
| Hoshiai, K | 2 |
| Akie, Y | 2 |
| Sugiyama, A | 2 |
| Yokoyama, H | 1 |
| Nakamura, Y | 1 |
| Nagayama, Y | 1 |
| Wada, T | 1 |
| Ando, K | 1 |
| Hamlin, RL | 1 |
| Kijtawornrat, A | 1 |
| Keene, BW | 1 |
| Hamlin, DM | 1 |
| Tabo, M | 1 |
| Nakamura, M | 1 |
| Kimura, K | 1 |
| Ito, S | 1 |
| Yorimitsu, M | 1 |
| Okada, S | 1 |
| Yamaguchi-Shima, N | 1 |
| Shimizu, T | 1 |
| Arai, J | 1 |
| Yokotani, K | 1 |
| Brooks, RR | 1 |
| Finch, SL | 1 |
| Baczkó, I | 1 |
| El-Reyani, NE | 1 |
| Farkas, A | 1 |
| Virág, L | 1 |
| Iost, N | 1 |
| Leprán, I | 1 |
| Mátyus, P | 1 |
| Varró, A | 1 |
| Papp, JG | 1 |
| Watanabe, T | 1 |
| Aviado, DM | 1 |
| Spinelli, W | 1 |
| Parsons, RW | 1 |
| Colatsky, TJ | 1 |
| Gwilt, M | 1 |
| Blackburn, KJ | 1 |
| Burges, RA | 1 |
| Higgins, AJ | 1 |
| Milne, AA | 1 |
| Solca, AM | 1 |
| Sano, T | 1 |
| Sugiyama, S | 1 |
| Taki, K | 1 |
| Hanaki, Y | 1 |
| Shimada, Y | 1 |
| Ozawa, T | 1 |
| Schmidt, M | 1 |
| Giesen-Crouse, E | 1 |
| Imbs, JL | 1 |
| Lawson, JW | 1 |
13 other studies available for sotalol and Anesthesia
| Article | Year |
|---|---|
In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state.
Topics: Anesthesia; Animals; Consciousness; Dogs; Electrocardiography; Halothane; Isoflurane; Male; Nitrous | 2021 |
Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Electrocardiography; Halo | 2017 |
QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cisapride; Consciousness; Electro | 2003 |
QT-RR relationships and suitable QT correction formulas for halothane-anesthetized dogs.
Topics: Analysis of Variance; Anesthesia; Animals; Astemizole; Dogs; Electrocardiography; Halothane; Male; P | 2006 |
Role of brain adrenoceptors in the corticortopin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonist | 2008 |
Effects of intravenous azimilide on cardiac performance, fibrillation threshold, and hemodynamics in anesthetized dogs.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Electrocardiogr | 2000 |
Antiarrhythmic and electrophysiological effects of GYKI-16638, a novel N-(phenoxyalkyl)-N-phenylalkylamine, in rabbits.
Topics: Action Potentials; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models | 2000 |
Toxicity of aerosol propellants in the respiratory and circulatory systems. VII. Influence of pulmonary emphysema and anesthesia in the rat.
Topics: Adrenergic beta-Antagonists; Aerosol Propellants; Aerosols; Anesthesia; Animals; Arrhythmias, Cardia | 1975 |
Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Benzimidazoles; Dogs; Electrocar | 1992 |
Electropharmacology of dofetilide, a new class III agent, in anaesthetised dogs.
Topics: Action Potentials; Anesthesia; Animals; Anti-Arrhythmia Agents; Dogs; Heart; Heart Ventricles; Hemod | 1992 |
Effects of antiarrhythmic agents classified as class III group on ischaemia-induced myocardial damage in canine hearts.
Topics: Acetylglucosaminidase; Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Coro | 1990 |
Renal and iliac vascular effects of dopamine in the anaesthetized rat.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Butaclamol; Dopamine; Drug Interact | 1987 |
Inhibition of quinidine-propranolol elevation of the ventricular fibrillation threshold by bilateral stellectomy+vagotomy in the anesthetized dog.
Topics: Anesthesia; Animals; Denervation; Dogs; Electric Stimulation; Female; Heart; Male; Propranolol; Quin | 1986 |