sotalol has been researched along with Acute Disease in 14 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment." | 9.08 | Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995) |
| "The aim of the present study was to characterize the influence of D,L-sotalol on arterial baroreflex sensitivity (BRS) which is generally considered as an estimate of vagal activity and has prognostic value in patients after myocardial infarction (MI)." | 7.71 | d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction. ( Haass, M; Krüger, C; Kübler, W; Landerer, V; Zugck, C, 2001) |
| "This study was designed to determine the hemodynamic effects of the class III antiarrhythmic agent d-sotalol in acute ischemic heart failure at concentrations that prolong ventricular repolarization." | 7.68 | Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs. ( Kløw, NE; Mortensen, E; Refsum, H; Tande, PM, 1992) |
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 7.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| "A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation." | 5.27 | Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986) |
| "We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment." | 5.08 | Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995) |
| "The aim of the present study was to characterize the influence of D,L-sotalol on arterial baroreflex sensitivity (BRS) which is generally considered as an estimate of vagal activity and has prognostic value in patients after myocardial infarction (MI)." | 3.71 | d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction. ( Haass, M; Krüger, C; Kübler, W; Landerer, V; Zugck, C, 2001) |
| "Intravenous amiodarone is an effective treatment for supraventricular and ventricular tachyarrhythmias." | 3.69 | Acute pulmonary toxicity in an infant from intravenous amiodarone. ( Daniels, CJ; Franklin, WH; Hammond, S; Schutte, DA, 1997) |
| "This study was designed to determine the hemodynamic effects of the class III antiarrhythmic agent d-sotalol in acute ischemic heart failure at concentrations that prolong ventricular repolarization." | 3.68 | Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs. ( Kløw, NE; Mortensen, E; Refsum, H; Tande, PM, 1992) |
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 3.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| "The amiodarone was omitted in 17 cases because of its side effects." | 1.32 | [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium]. ( Borbély, M; Dani, G; Erdej, F; Hajdara, I; Katona, A; Márk, L; Nagy, E; Sziklai, G, 2004) |
| "A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation." | 1.27 | Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lip, GY | 1 |
| Watson, T | 1 |
| Tereshchenko, SN | 1 |
| Bulanova, NA | 1 |
| Kositsyna, IV | 1 |
| Morozova, MN | 1 |
| Uteshev, IuA | 1 |
| Márk, L | 1 |
| Erdej, F | 1 |
| Dani, G | 1 |
| Borbély, M | 1 |
| Sziklai, G | 1 |
| Nagy, E | 1 |
| Hajdara, I | 1 |
| Katona, A | 1 |
| Halinen, MO | 1 |
| Huttunen, M | 1 |
| Paakkinen, S | 1 |
| Tarssanen, L | 1 |
| Schwartz, PJ | 1 |
| Daniels, CJ | 1 |
| Schutte, DA | 1 |
| Hammond, S | 1 |
| Franklin, WH | 1 |
| Lau, CP | 1 |
| Lok, NS | 1 |
| Kulmatycki, KM | 1 |
| Abouchehade, K | 1 |
| Sattari, S | 1 |
| Jamali, F | 1 |
| Krüger, C | 1 |
| Zugck, C | 1 |
| Landerer, V | 1 |
| Kübler, W | 1 |
| Haass, M | 1 |
| Mortensen, E | 1 |
| Tande, PM | 1 |
| Kløw, NE | 1 |
| Refsum, H | 1 |
| Muller, CA | 1 |
| Opie, LH | 1 |
| Hamm, CW | 1 |
| Peisach, M | 1 |
| Gihwala, D | 1 |
| Cobbe, SM | 2 |
| Manley, BS | 2 |
| Alexopoulos, D | 2 |
| Kentala, E | 1 |
| Pyörälä, K | 1 |
| Frick, MH | 1 |
2 reviews available for sotalol and Acute Disease
| Article | Year |
|---|---|
Atrial fibrillation (acute onset).
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Sotalol | 2008 |
[Chronic heart failure and atrial fibrilation: aspects of management].
Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmi | 2003 |
3 trials available for sotalol and Acute Disease
| Article | Year |
|---|---|
Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).
Topics: Acute Disease; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Female; Heart R | 1995 |
[Prevention of sudden death in myocardial infarct: do experimental results help to understand the clinical reality? The case of the clinical trial SWORD (Survival With ORal D-sotalol)].
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Drug Therapy, Combination; Femal | 1996 |
Sotalol in the treatment of angina pectoris. A double-blind cross-over study.
Topics: Acute Disease; Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Cardiac Volume; Clinica | 1974 |
9 other studies available for sotalol and Acute Disease
| Article | Year |
|---|---|
[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrill | 2004 |
Acute pulmonary toxicity in an infant from intravenous amiodarone.
Topics: Acute Disease; Amiodarone; Bronchoalveolar Lavage Fluid; Dobutamine; Humans; Infant; Infant, Newborn | 1997 |
A comparison of transvenous atrial defibrillation of acute and chronic atrial fibrillation and the effect of intravenous sotalol on human atrial defibrillation threshold.
Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Combined Modality Thera | 1997 |
Drug-disease interactions: reduced beta-adrenergic and potassium channel antagonist activities of sotalol in the presence of acute and chronic inflammatory conditions in the rat.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Antibodies, Monoclonal; Area Under Curve; Biolo | 2001 |
d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction.
Topics: Acute Disease; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baroreflex; Blood Pressur | 2001 |
Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs.
Topics: Acute Disease; Animals; Coronary Disease; Diastole; Disease Models, Animal; Dogs; Dose-Response Rela | 1992 |
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circu | 1986 |
The influence of acute myocardial ischaemia on the class III antiarrhythmic action of sotalol.
Topics: Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Electric Stimul | 1985 |
Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol.
Topics: Acidosis; Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Cultu | 1985 |