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sotalol and Acute Disease

sotalol has been researched along with Acute Disease in 14 studies

Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment."9.08Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995)
"The aim of the present study was to characterize the influence of D,L-sotalol on arterial baroreflex sensitivity (BRS) which is generally considered as an estimate of vagal activity and has prognostic value in patients after myocardial infarction (MI)."7.71d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction. ( Haass, M; Krüger, C; Kübler, W; Landerer, V; Zugck, C, 2001)
"This study was designed to determine the hemodynamic effects of the class III antiarrhythmic agent d-sotalol in acute ischemic heart failure at concentrations that prolong ventricular repolarization."7.68Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs. ( Kløw, NE; Mortensen, E; Refsum, H; Tande, PM, 1992)
"The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ."7.67Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985)
"A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation."5.27Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986)
"We randomized 61 patients with paroxysmal atrial fibrillation (AF) ( < 48 hours from onset) to either sotalol or quinidine treatment."5.08Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial). ( Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L, 1995)
"The aim of the present study was to characterize the influence of D,L-sotalol on arterial baroreflex sensitivity (BRS) which is generally considered as an estimate of vagal activity and has prognostic value in patients after myocardial infarction (MI)."3.71d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction. ( Haass, M; Krüger, C; Kübler, W; Landerer, V; Zugck, C, 2001)
"Intravenous amiodarone is an effective treatment for supraventricular and ventricular tachyarrhythmias."3.69Acute pulmonary toxicity in an infant from intravenous amiodarone. ( Daniels, CJ; Franklin, WH; Hammond, S; Schutte, DA, 1997)
"This study was designed to determine the hemodynamic effects of the class III antiarrhythmic agent d-sotalol in acute ischemic heart failure at concentrations that prolong ventricular repolarization."3.68Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs. ( Kløw, NE; Mortensen, E; Refsum, H; Tande, PM, 1992)
"The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ."3.67Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985)
"The amiodarone was omitted in 17 cases because of its side effects."1.32[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium]. ( Borbély, M; Dani, G; Erdej, F; Hajdara, I; Katona, A; Márk, L; Nagy, E; Sziklai, G, 2004)
"A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation."1.27Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's5 (35.71)18.2507
2000's5 (35.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lip, GY1
Watson, T1
Tereshchenko, SN1
Bulanova, NA1
Kositsyna, IV1
Morozova, MN1
Uteshev, IuA1
Márk, L1
Erdej, F1
Dani, G1
Borbély, M1
Sziklai, G1
Nagy, E1
Hajdara, I1
Katona, A1
Halinen, MO1
Huttunen, M1
Paakkinen, S1
Tarssanen, L1
Schwartz, PJ1
Daniels, CJ1
Schutte, DA1
Hammond, S1
Franklin, WH1
Lau, CP1
Lok, NS1
Kulmatycki, KM1
Abouchehade, K1
Sattari, S1
Jamali, F1
Krüger, C1
Zugck, C1
Landerer, V1
Kübler, W1
Haass, M1
Mortensen, E1
Tande, PM1
Kløw, NE1
Refsum, H1
Muller, CA1
Opie, LH1
Hamm, CW1
Peisach, M1
Gihwala, D1
Cobbe, SM2
Manley, BS2
Alexopoulos, D2
Kentala, E1
Pyörälä, K1
Frick, MH1

Reviews

2 reviews available for sotalol and Acute Disease

ArticleYear
Atrial fibrillation (acute onset).
    BMJ clinical evidence, 2008, May-02, Volume: 2008

    Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Sotalol

2008
[Chronic heart failure and atrial fibrilation: aspects of management].
    Kardiologiia, 2003, Volume: 43, Issue:10

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmi

2003

Trials

3 trials available for sotalol and Acute Disease

ArticleYear
Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).
    The American journal of cardiology, 1995, Sep-01, Volume: 76, Issue:7

    Topics: Acute Disease; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Female; Heart R

1995
[Prevention of sudden death in myocardial infarct: do experimental results help to understand the clinical reality? The case of the clinical trial SWORD (Survival With ORal D-sotalol)].
    Cardiologia (Rome, Italy), 1996, Volume: 41, Issue:8

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Drug Therapy, Combination; Femal

1996
Sotalol in the treatment of angina pectoris. A double-blind cross-over study.
    Annals of clinical research, 1974, Volume: 6, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Cardiac Volume; Clinica

1974

Other Studies

9 other studies available for sotalol and Acute Disease

ArticleYear
[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].
    Orvosi hetilap, 2004, May-09, Volume: 145, Issue:19

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrill

2004
Acute pulmonary toxicity in an infant from intravenous amiodarone.
    The American journal of cardiology, 1997, Oct-15, Volume: 80, Issue:8

    Topics: Acute Disease; Amiodarone; Bronchoalveolar Lavage Fluid; Dobutamine; Humans; Infant; Infant, Newborn

1997
A comparison of transvenous atrial defibrillation of acute and chronic atrial fibrillation and the effect of intravenous sotalol on human atrial defibrillation threshold.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:10 Pt 1

    Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Combined Modality Thera

1997
Drug-disease interactions: reduced beta-adrenergic and potassium channel antagonist activities of sotalol in the presence of acute and chronic inflammatory conditions in the rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:2

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Antibodies, Monoclonal; Area Under Curve; Biolo

2001
d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction.
    Pharmacological research, 2001, Volume: 44, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baroreflex; Blood Pressur

2001
Hemodynamic effects of d-sotalol in acute ischemic heart failure in dogs.
    American heart journal, 1992, Volume: 123, Issue:4 Pt 1

    Topics: Acute Disease; Animals; Coronary Disease; Diastole; Disease Models, Animal; Dogs; Dose-Response Rela

1992
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:4

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circu

1986
The influence of acute myocardial ischaemia on the class III antiarrhythmic action of sotalol.
    Cardiovascular research, 1985, Volume: 19, Issue:11

    Topics: Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Electric Stimul

1985
Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol.
    Cardiovascular research, 1985, Volume: 19, Issue:11

    Topics: Acidosis; Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Cultu

1985