sotalol has been researched along with Acidosis in 4 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 7.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| "The effects of hypoxia on the actions of dl-sotalol 10(-4) mol ." | 3.67 | Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol. ( Alexopoulos, D; Cobbe, SM; Manley, BS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riegle, KM | 1 |
| Clancy, RL | 1 |
| Yang, T | 1 |
| Tande, PM | 1 |
| Refsum, H | 1 |
| Abiko, Y | 1 |
| Ichihara, K | 1 |
| Sakai, K | 1 |
| Cobbe, SM | 1 |
| Manley, BS | 1 |
| Alexopoulos, D | 1 |
4 other studies available for sotalol and Acidosis
| Article | Year |
|---|---|
Effect of norepinephrine on myocardial intracellular hydrogen ion concentration.
Topics: Acid-Base Imbalance; Acidosis; Animals; Bicarbonates; Carbon Dioxide; Hydrogen-Ion Concentration; Hy | 1975 |
Electromechanical action of dofetilide and D-sotalol during simulated metabolic acidosis in isolated guinea pig ventricular muscle.
Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Female; Guinea Pigs; Heart; Heart Vent | 1992 |
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart.
Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Technique | 1987 |
Interaction of the effects of hypoxia, substrate depletion, acidosis and hyperkalaemia on the class III antiarrhythmic properties of sotalol.
Topics: Acidosis; Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Coronary Disease; Cultu | 1985 |