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sorbitol and Uremia

sorbitol has been researched along with Uremia in 18 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Sodium polystyrene sulphonate (Resonium A) in sorbitol given as an enema or orally to treat hyperkalaemia has been described to induce intestinal necrosis in uraemic patients."7.71Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant. ( Boudová, L; Chlumská, A; Pavlovský, M; Sulc, M, 2002)
"Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients."7.69Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997)
"Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency."7.69Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997)
" All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis."7.67Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987)
"Sodium polystyrene sulphonate (Resonium A) in sorbitol given as an enema or orally to treat hyperkalaemia has been described to induce intestinal necrosis in uraemic patients."3.71Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant. ( Boudová, L; Chlumská, A; Pavlovský, M; Sulc, M, 2002)
"Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients."3.69Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997)
"Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency."3.69Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997)
" All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis."3.67Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's4 (22.22)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chlumská, A1
Boudová, L1
Pavlovský, M1
Sulc, M1
Zuliani, U1
Bonetti, A1
Orlandini, G1
Manari, A1
David, S1
Garini, G1
Rashid, A1
Hamilton, SR2
Gardiner, GW1
Marion, F1
Joye, F1
Tsukushi, S1
Katsuzaki, T1
Aoyama, I1
Takayama, F1
Miyazaki, T1
Shimokata, K1
Niwa, T1
Iarmolinskiĭ, IS1
Treĭzon, IaB1
Kremer, IuN1
Romolo, JL2
Williams, GM2
Saltzman, MJ1
Beyer, MM1
Friedman, EA1
Sterzel, RB1
Servo, C1
Pitkänen, E1
Lillemoe, KD1
Pennington, LR1
Burdick, JF1
DeJesus, PV1
Clements, RS1
Winegrad, AI1
Seifart, VW1
Burkhardt, G1
Talner, LB1
Mauer, SM1
Shideman, JR1
Buselmeier, TJ1
Kjellstrand, CM1
Aloia, JF1
Bischel, MD1
Barbour, BH1

Reviews

1 review available for sorbitol and Uremia

ArticleYear
Urographic contrast media in uremia. Physiology and pharmacology.
    Radiologic clinics of North America, 1972, Volume: 10, Issue:3

    Topics: Animals; Anuria; Contrast Media; Diatrizoate; Diuresis; Dogs; Glomerular Filtration Rate; Humans; In

1972

Trials

1 trial available for sorbitol and Uremia

ArticleYear
Peritoneal dialysis with sorbitol versus dextrose dialysate. Clinical findings and alterations of blood and cerebrospinal fluid.
    Nephron, 1974, Volume: 12, Issue:6

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amylases; Aspartate Aminotransferases; Blood Gluc

1974

Other Studies

16 other studies available for sorbitol and Uremia

ArticleYear
Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant.
    Ceskoslovenska patologie, 2002, Volume: 38, Issue:4

    Topics: Diuretics, Osmotic; Drug Therapy, Combination; Enema; Female; Humans; Infant, Newborn; Infant, Prema

2002
[Pharmacokinetics and antilipolytic effect of a derivative of nicotinic acid (sorbinicate) in dialyzed uremic patients].
    Il Farmaco; edizione pratica, 1981, Volume: 36, Issue:9

    Topics: Female; Humans; Hypolipidemic Agents; Kinetics; Lipolysis; Male; Middle Aged; Nicotinic Acids; Renal

1981
Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition.
    The American journal of surgical pathology, 1997, Volume: 21, Issue:1

    Topics: Adult; Aged; Cation Exchange Resins; Child, Preschool; Cholestyramine Resin; Crystallization; Digest

1997
Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1997, Volume: 11, Issue:7

    Topics: Aged; Cation Exchange Resins; Colon; Diuretics, Osmotic; Drug Therapy, Combination; Fatal Outcome; F

1997
[Polystyrene sodium sulfonate enema: with or without sorbitol?].
    Presse medicale (Paris, France : 1983), 1999, Feb-20, Volume: 28, Issue:7

    Topics: Administration, Oral; Enema; Humans; Intestinal Mucosa; Kidney Failure, Chronic; Necrosis; Polystyre

1999
Increased erythrocyte 3-DG and AGEs in diabetic hemodialysis patients: role of the polyol pathway.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: Adult; Aged; Aldehyde Reductase; Arginine; Creatinine; Deoxyglucose; Diabetic Nephropathies; Enzyme-

1999
[Diet therapy in patients with uremia].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:1

    Topics: Diet Fads; Dietary Proteins; Fructose; Glucose; Humans; Parenteral Nutrition; Sorbitol; Uremia; Xyli

1977
Effect of kayexalate and sorbitol on colon of normal and uremic rats.
    Surgical forum, 1979, Volume: 30

    Topics: Animals; Colon; Enema; Male; Nephrectomy; Polystyrenes; Rats; Sorbitol; Uremia

1979
Mechanism of life prolongation in nephrectomized rats treated with oxidized starch and charcoal.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Animals; Blood Urea Nitrogen; Charcoal; Hyperkalemia; Male; Nephrectomy; Polystyrenes; Potassium; Ra

1976
[Treatment of reversible, uremia-inducing factors in chronic interstitial nephritis].
    Deutsche medizinische Wochenschrift (1946), 1975, Feb-07, Volume: 100, Issue:6

    Topics: Blood Volume; Central Venous Pressure; Chronic Disease; Furosemide; Humans; Kidney; Nephritis, Inter

1975
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.
    Diabetologia, 1975, Volume: 11, Issue:6

    Topics: Aged; Blood Glucose; Creatinine; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Ethers, Cy

1975
Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis.
    Surgery, 1987, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Animals; Colon; Enema; Female; Humans; Hyperkalemia; Male; Middle Aged; Necrosis;

1987
Hypermyoinositolemic polyneuropathy in rats. A possible mechanism for uremic polyneuropathy.
    Journal of the neurological sciences, 1974, Volume: 21, Issue:3

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Electric Stimulation; Evoked Po

1974
[Forced osmodiuresis in peritonitis].
    Zentralblatt fur Chirurgie, 1974, Dec-13, Volume: 99, Issue:50

    Topics: Diuresis; Diuretics, Osmotic; Furosemide; Humans; Mannitol; Osmolar Concentration; Peritonitis; Sorb

1974
Long-term hemodialysis in the neonatal period.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:2

    Topics: Arteriovenous Shunt, Surgical; Blood Urea Nitrogen; Creatinine; Female; Glucose; Growth Disorders; H

1973
Monosaccharides and polyols in diabetes mellitus and uremia.
    The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:5

    Topics: Adult; Aged; Blood Glucose; Chromatography, Gas; Diabetes Mellitus; Female; Fructose; Humans; Inosit

1973