Page last updated: 2024-11-06

sorbitol and Poisoning

sorbitol has been researched along with Poisoning in 14 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."7.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."3.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
" No clinical studies have been published to investigate the ability of a cathartic, with or without activated charcoal, to reduce the bioavailability of drugs or to improve the outcome of poisoned patients."2.42Position paper: cathartics. ( , 2004)
" No clinical studies have been published to investigate the ability of a cathartic, with or without activated charcoal, to reduce the bioavailability of drugs or to improve the outcome of poisoned patients."2.40Position statement: cathartics. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. ( Barceloux, D; Hartigan-Go, K; McGuigan, M, 1997)
" Though a prospective, controlled study needs to be performed, variation in dosage of the CSS may be appropriate in select patient groups to offset the effects of the ingestant on bowel motility."1.28Gastrointestinal transit times of a charcoal/sorbitol slurry in overdose patients. ( Cottington, E; Harchelroad, F; Krenzelok, EP, 1989)
" A study was done in volunteers to determine the rapidity of gastrointestinal transit when activated charcoal was administered with various cathartics."1.27Gastrointestinal transit times of cathartics combined with charcoal. ( Keller, R; Krenzelok, EP; Stewart, RD, 1985)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's6 (42.86)18.2507
2000's1 (7.14)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shinya, H1
James, LP1
Nichols, MH1
King, WD1
Scharman, EJ1
Krenzelok, EP3
Barceloux, D1
McGuigan, M1
Hartigan-Go, K1
Abernethy, MK1
Becker, LB1
Kobrle, V1
Hurych, J1
Cikrt, M1
Jones, MM1
Allerton, JP1
Strom, JA1
Harchelroad, F1
Cottington, E1
Krenzelok, E1
Keller, R1
Stewart, RD1
Schydlo, R1
Dederichs, M1
Younger, RL1
Wright, FC1
Rauen, HM1
Schriewer, H1

Reviews

2 reviews available for sorbitol and Poisoning

ArticleYear
Position paper: cathartics.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:3

    Topics: Animals; Cathartics; Charcoal; Citric Acid; Contraindications; Humans; Organometallic Compounds; Poi

2004
Position statement: cathartics. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:7

    Topics: Animals; Antidotes; Biological Availability; Cathartics; Charcoal; Citric Acid; Contraindications; D

1997

Trials

1 trial available for sorbitol and Poisoning

ArticleYear
A comparison of cathartics in pediatric ingestions.
    Pediatrics, 1995, Volume: 96, Issue:2 Pt 1

    Topics: Cathartics; Charcoal; Child, Preschool; Citrates; Citric Acid; Defecation; Double-Blind Method; Fece

1995

Other Studies

11 other studies available for sorbitol and Poisoning

ArticleYear
[Effect of the second dose of sorbitol].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2011, Volume: 24, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Cathartics; Charcoal; Defecation; Female; Humans; Male; Midd

2011
Nursing attitudes towards charcoal administration--impact on patient care.
    Veterinary and human toxicology, 1994, Volume: 36, Issue:5

    Topics: Attitude of Health Personnel; Charcoal; Data Collection; Emergency Service, Hospital; Ethics, Nursin

1994
Acute nutmeg intoxication.
    The American journal of emergency medicine, 1992, Volume: 10, Issue:5

    Topics: Adult; Anxiety; Charcoal; Condiments; Humans; Male; Paranoid Behavior; Poisoning; Sorbitol; Tachycar

1992
Sodium bis(hydroxyethyl)dithiocarbamate reduces acute lung tissue damage induced by cadmium in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:4

    Topics: Animals; Cadmium; Cadmium Poisoning; Connective Tissue; Copper; Ditiocarb; Lung; Lung Diseases; Male

1991
Hypernatremia due to repeated doses of charcoal-sorbitol.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:5

    Topics: Adult; Cathartics; Charcoal; Female; Humans; Hypernatremia; Phenobarbital; Poisoning; Sorbitol; Susp

1991
Gastrointestinal transit times of a charcoal/sorbitol slurry in overdose patients.
    Journal of toxicology. Clinical toxicology, 1989, Volume: 27, Issue:1-2

    Topics: Adolescent; Adult; Charcoal; Female; Gastrointestinal Transit; Humans; Male; Poisoning; Retrospectiv

1989
Sorbitol--a safe and effective cathartic.
    Annals of emergency medicine, 1987, Volume: 16, Issue:6

    Topics: Cathartics; Humans; Magnesium; Poisoning; Sorbitol

1987
Gastrointestinal transit times of cathartics combined with charcoal.
    Annals of emergency medicine, 1985, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Cathartics; Charcoal; Citrates; Citric Acid; Digestive System; Drug The

1985
[Carbromal-intoxication among children (author's transl)].
    Klinische Padiatrie, 1973, Volume: 185, Issue:6

    Topics: Adolescent; Child, Preschool; Female; Gastric Lavage; Humans; Infant; Ipecac; Male; Poisoning; Sorbi

1973
Acute coumaphos toxicosis in cattle: antidotal therapy with pralidoxime chloride and atropine, and related alterations of blood and serum enzymatic activities.
    American journal of veterinary research, 1971, Volume: 32, Issue:7

    Topics: Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Atropine; Cattle; Cattle Diseases; Ch

1971
[Correlations of enzyme activities in serum after experimental liver damage in rats].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:8

    Topics: Acetamides; Alanine Transaminase; Alcohol Oxidoreductases; Alcoholic Intoxication; Alkaline Phosphat

1971