sorbitol has been researched along with Necrosis in 38 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intestinal necrosis associated with cation exchange resin (CER) is considered related to sorbitol, but it has been reported even in patients receiving CER alone." | 7.96 | Intestinal necrosis related to administration of cation exchange resin without sorbitol: A retrospective analysis of 61 patients with end-stage renal diseases. ( Kawagishi, N; Miyasaka, Y; Murakami, K; Nakamura, Y; Sasano, H; Sato, T, 2020) |
| "Based on a single rat study by Lillemoe et al, the consensus has been formed to implicate sorbitol rather than sodium polystyrene sulfonate (SPS) as the culprit for colon necrosis in humans treated with SPS and sorbitol." | 7.81 | Colon Necrosis Due to Sodium Polystyrene Sulfonate with and without Sorbitol: An Experimental Study in Rats. ( Ayoub, I; Babinska, A; Gupta, R; McFarlane, M; Oh, MS; Salifu, MO, 2015) |
| "Colonic necrosis has been reported after sodium polystyrene sulfonate (SPS)/sorbitol use, but the incidence and relative risk (RR) are not established." | 7.78 | Association of prescription of oral sodium polystyrene sulfonate with sorbitol in an inpatient setting with colonic necrosis: a retrospective cohort study. ( Abbott, KC; Baker, TP; Nguyen, A; Oliver, DK; Sebastianelli, ME; Stewart, HL; Watson, MA; Yuan, CM, 2012) |
| "To describe a case of extensive intestinal necrosis with oral intake of calcium polystyrene sulfonate without sorbitol." | 7.77 | Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol. ( Bordes, J; Goutorbe, P; Lacroix, G; Meaudre, E; Montcriol, A; Souraud, JB, 2011) |
| "Intestinal ischemia is a recognized risk of SPS in sorbitol." | 7.75 | Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol. ( Chu, G; McGowan, CE; Moss, SF; Resnick, MB; Saha, S, 2009) |
| "Sodium polystyrene sulphonate (Resonium A) in sorbitol given as an enema or orally to treat hyperkalaemia has been described to induce intestinal necrosis in uraemic patients." | 7.71 | Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant. ( Boudová, L; Chlumská, A; Pavlovský, M; Sulc, M, 2002) |
| "Colonic necrosis is an unusual complication after treatment of hyperkalemia with sodium polystyrene sulfonate (SPS, Kayexalate) in sorbitol." | 7.70 | Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol. ( Barbul, A; Dardik, A; Efron, G; Harrison, MG; Moesinger, RC, 2000) |
| "Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients." | 7.69 | Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997) |
| "Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency." | 7.69 | Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997) |
| " All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis." | 7.67 | Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987) |
| "Intestinal necrosis associated with cation exchange resin (CER) is considered related to sorbitol, but it has been reported even in patients receiving CER alone." | 3.96 | Intestinal necrosis related to administration of cation exchange resin without sorbitol: A retrospective analysis of 61 patients with end-stage renal diseases. ( Kawagishi, N; Miyasaka, Y; Murakami, K; Nakamura, Y; Sasano, H; Sato, T, 2020) |
| "Various types of cell death, including apoptosis, necrosis, necroptosis, and ferroptosis, are induced in renal tubular epithelial cells following exposure to environmental stresses and toxicants such as osmotic stress, ischemia/reperfusion injury, cisplatin, and cadmium." | 3.91 | Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms. ( Fujiki, K; Inamura, H; Matsuoka, M; Sugaya, T, 2019) |
| "A rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake." | 3.81 | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate. ( Chiang, WC; Kao, CC; Kao, TW; Mao, TL; Tsai, YC, 2015) |
| "Colonic necrosis has been reported after sodium polystyrene sulfonate (SPS)/sorbitol use, but the incidence and relative risk (RR) are not established." | 3.78 | Association of prescription of oral sodium polystyrene sulfonate with sorbitol in an inpatient setting with colonic necrosis: a retrospective cohort study. ( Abbott, KC; Baker, TP; Nguyen, A; Oliver, DK; Sebastianelli, ME; Stewart, HL; Watson, MA; Yuan, CM, 2012) |
| "To describe a case of extensive intestinal necrosis with oral intake of calcium polystyrene sulfonate without sorbitol." | 3.77 | Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol. ( Bordes, J; Goutorbe, P; Lacroix, G; Meaudre, E; Montcriol, A; Souraud, JB, 2011) |
| " In 2009, the FDA recommended that sorbitol, a cathartic often given with SPS to prevent obstipation, not be added to SPS powder because of associated colonic necrosis." | 3.76 | Damned if you do, damned if you don't: potassium binding resins in hyperkalemia. ( Abbott, KC; Watson, M; Yuan, CM, 2010) |
| "Intestinal ischemia is a recognized risk of SPS in sorbitol." | 3.75 | Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol. ( Chu, G; McGowan, CE; Moss, SF; Resnick, MB; Saha, S, 2009) |
| "Sodium polystyrene sulphonate (Resonium A) in sorbitol given as an enema or orally to treat hyperkalaemia has been described to induce intestinal necrosis in uraemic patients." | 3.71 | Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant. ( Boudová, L; Chlumská, A; Pavlovský, M; Sulc, M, 2002) |
| "Colonic necrosis is an unusual complication after treatment of hyperkalemia with sodium polystyrene sulfonate (SPS, Kayexalate) in sorbitol." | 3.70 | Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol. ( Barbul, A; Dardik, A; Efron, G; Harrison, MG; Moesinger, RC, 2000) |
| "Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients." | 3.69 | Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997) |
| "Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency." | 3.69 | Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997) |
| " All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis." | 3.67 | Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987) |
| " However, its use has been associated with colonic necrosis and other fatal gastrointestinal adverse events." | 2.49 | Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review. ( Bell, CM; Harel, S; Harel, Z; Perl, J; Shah, PS; Wald, R, 2013) |
| "Hyperkalemia is a common condition encountered in medical and surgical patients." | 1.35 | Ileocolic perforation secondary to sodium polystyrene sulfonate in sorbitol use: a case report. ( Drolet, S; Morcos, MW; Trottier, V, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (28.95) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 12 (31.58) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Murakami, K | 1 |
| Nakamura, Y | 1 |
| Miyasaka, Y | 1 |
| Sato, T | 1 |
| Kawagishi, N | 1 |
| Sasano, H | 1 |
| Fujiki, K | 1 |
| Inamura, H | 1 |
| Sugaya, T | 1 |
| Matsuoka, M | 1 |
| Kao, CC | 1 |
| Tsai, YC | 1 |
| Chiang, WC | 1 |
| Mao, TL | 1 |
| Kao, TW | 1 |
| Castillo-Cejas, MD | 1 |
| de-Torres-Ramírez, I | 1 |
| Alonso-Cotoner, C | 1 |
| Ayoub, I | 1 |
| Oh, MS | 1 |
| Gupta, R | 1 |
| McFarlane, M | 1 |
| Babinska, A | 1 |
| Salifu, MO | 1 |
| Usta, Y | 1 |
| Ramirez, C | 1 |
| Dennert, B | 1 |
| Dalvin, LA | 1 |
| Garcia, MD | 1 |
| Salomão, DR | 1 |
| Iezzi, R | 1 |
| Barkmeier, AJ | 1 |
| McGowan, CE | 1 |
| Saha, S | 1 |
| Chu, G | 1 |
| Resnick, MB | 1 |
| Moss, SF | 1 |
| Trottier, V | 1 |
| Drolet, S | 1 |
| Morcos, MW | 1 |
| Wu, LY | 1 |
| Ma, ZM | 1 |
| Fan, XL | 1 |
| Zhao, T | 1 |
| Liu, ZH | 1 |
| Huang, X | 1 |
| Li, MM | 1 |
| Xiong, L | 1 |
| Zhang, K | 1 |
| Zhu, LL | 1 |
| Fan, M | 1 |
| Watson, M | 1 |
| Abbott, KC | 2 |
| Yuan, CM | 2 |
| Goutorbe, P | 1 |
| Montcriol, A | 1 |
| Lacroix, G | 1 |
| Bordes, J | 1 |
| Meaudre, E | 1 |
| Souraud, JB | 1 |
| Chou, YH | 1 |
| Wang, HY | 1 |
| Hsieh, MS | 1 |
| Watson, MA | 1 |
| Baker, TP | 1 |
| Nguyen, A | 1 |
| Sebastianelli, ME | 1 |
| Stewart, HL | 1 |
| Oliver, DK | 1 |
| Harel, Z | 1 |
| Harel, S | 1 |
| Shah, PS | 1 |
| Wald, R | 1 |
| Perl, J | 1 |
| Bell, CM | 1 |
| Chlumská, A | 1 |
| Boudová, L | 1 |
| Pavlovský, M | 1 |
| Sulc, M | 1 |
| ASADA, M | 1 |
| GALAMBOS, JT | 1 |
| SCHLANT, RC | 1 |
| RAWLS, WJ | 1 |
| Kelsey, PB | 1 |
| Chen, S | 1 |
| Lauwers, GY | 1 |
| Hahn, RG | 1 |
| Nennesmo, I | 1 |
| Rajs, J | 1 |
| Sundelin, B | 1 |
| Wróblewski, R | 1 |
| Zhang, W | 1 |
| Rashid, A | 1 |
| Hamilton, SR | 2 |
| Gardiner, GW | 1 |
| Marion, F | 1 |
| Joye, F | 1 |
| Dardik, A | 1 |
| Moesinger, RC | 1 |
| Efron, G | 1 |
| Barbul, A | 1 |
| Harrison, MG | 1 |
| Rogers, FB | 1 |
| Li, SC | 1 |
| Koyama, AH | 1 |
| Irie, H | 1 |
| Ueno, F | 1 |
| Ogawa, M | 1 |
| Nomoto, A | 1 |
| Adachi, A | 1 |
| Lutzger, LG | 1 |
| Factor, SM | 1 |
| Bannai, C | 1 |
| Yamazaki, M | 1 |
| Matsushima, Y | 1 |
| Kunika, K | 1 |
| Itakura, M | 1 |
| Okuda, Y | 1 |
| Yamashita, K | 1 |
| Gerstman, BB | 1 |
| Kirkman, R | 1 |
| Platt, R | 1 |
| Burnett, RJ | 1 |
| Wootton, FT | 1 |
| Rhodes, DF | 1 |
| Lee, WM | 1 |
| Fitts, CT | 1 |
| Lillemoe, KD | 1 |
| Romolo, JL | 1 |
| Pennington, LR | 1 |
| Burdick, JF | 1 |
| Williams, GM | 1 |
| Hetzer, R | 1 |
| Balten, U | 1 |
| Nevermann, L | 1 |
| Vycoupil, KF | 1 |
| Walter, P | 1 |
| Borst, HG | 1 |
| Burke, MD | 1 |
| Thorpe, E | 1 |
| Gopinath, C | 1 |
| Jones, RS | 1 |
| Ford, EJ | 1 |
| Tkác, J | 1 |
| Sutta, J | 1 |
| Schulz, FW | 1 |
| Meesmann, W | 1 |
| Tüttemann, J | 1 |
| Maruhn, D | 1 |
| Schley, G | 1 |
| Heine, W | 1 |
| Schill, H | 1 |
| Tessmann, D | 1 |
| Kupatz, H | 1 |
| Enderle, A | 1 |
| Korb, G | 1 |
| Krug, A | 1 |
4 reviews available for sorbitol and Necrosis
| Article | Year |
|---|---|
Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: case report and literature review.
Topics: Administration, Oral; Adult; Colon; Colonoscopy; Crystallization; Humans; Male; Necrosis; Polystyren | 2011 |
Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review.
Topics: Cation Exchange Resins; Colonic Diseases; Drug Therapy, Combination; Female; Gastrointestinal Diseas | 2013 |
Acute colonic necrosis associated with sodium polystyrene sulfonate (Kayexalate) enemas in a critically ill patient: case report and review of the literature.
Topics: Colon; Colonic Diseases; Critical Care; Enema; Humans; Hyperkalemia; Male; Middle Aged; Necrosis; Po | 2001 |
Intestinal necrosis associated with postoperative orally administered sodium polystyrene sulfonate in sorbitol.
Topics: Administration, Oral; Adult; Aged; Cation Exchange Resins; Female; Humans; Incidence; Intestinal Dis | 1992 |
34 other studies available for sorbitol and Necrosis
| Article | Year |
|---|---|
Intestinal necrosis related to administration of cation exchange resin without sorbitol: A retrospective analysis of 61 patients with end-stage renal diseases.
Topics: Adult; Aged; Aged, 80 and over; Cation Exchange Resins; Female; Humans; Intestines; Kidney Failure, | 2020 |
Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms.
Topics: Activin Receptors, Type I; Activins; Apoptosis; Cadmium; Cell Death; Cell Line; Cisplatin; Epithelia | 2019 |
Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate.
Topics: Colon; Fatal Outcome; Female; Humans; Hyperkalemia; Ileum; Intestinal Perforation; Kidney Failure, C | 2015 |
Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.
Topics: Cation Exchange Resins; Colon; Humans; Hyperkalemia; Necrosis; Sorbitol | 2013 |
Colon Necrosis Due to Sodium Polystyrene Sulfonate with and without Sorbitol: An Experimental Study in Rats.
Topics: Animals; Colon; Humans; Male; Necrosis; Polystyrenes; Rats; Rats, Sprague-Dawley; Sorbitol | 2015 |
Image of the Month: Emphysematous Gastritis and Necrosis as a Result of Orally Ingested Sodium Polystyrene Sulfonate (Kayexalate) in Sorbitol.
Topics: Acute Kidney Injury; Aged; Cathartics; Chelating Agents; Gastritis; Gastroscopy; Humans; Hyperkalemi | 2016 |
Necrotizing Subconjunctival Granulomata and Intraoperative Use of Topical GenTeal Gel.
Topics: Acrylic Resins; Administration, Topical; Adult; Borates; Conjunctiva; Conjunctival Diseases; Drug Co | 2016 |
Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol.
Topics: Adult; Aged; Aged, 80 and over; Cathartics; Cation Exchange Resins; Cohort Studies; Female; Humans; | 2009 |
Ileocolic perforation secondary to sodium polystyrene sulfonate in sorbitol use: a case report.
Topics: Cathartics; Cation Exchange Resins; Colonic Diseases; Female; Humans; Hyperkalemia; Ileal Diseases; | 2009 |
The anti-necrosis role of hypoxic preconditioning after acute anoxia is mediated by aldose reductase and sorbitol pathway in PC12 cells.
Topics: Aldehyde Reductase; Animals; Berberine; Cell Hypoxia; Necrosis; PC12 Cells; Rats; RNA, Messenger; So | 2010 |
Damned if you do, damned if you don't: potassium binding resins in hyperkalemia.
Topics: Animals; Cathartics; Cation Exchange Resins; Colon; Drug Combinations; Drug Synergism; Evidence-Base | 2010 |
Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol.
Topics: Aged; Cecum; Colonic Pseudo-Obstruction; Fatal Outcome; Female; Humans; Hyperkalemia; Intestinal Muc | 2011 |
Association of prescription of oral sodium polystyrene sulfonate with sorbitol in an inpatient setting with colonic necrosis: a retrospective cohort study.
Topics: Administration, Oral; Age Distribution; Aged; Aged, 80 and over; Biopsy, Needle; Cohort Studies; Col | 2012 |
Intestinal necrosis following Calcium Resonium-sorbitol administration in a premature uraemic infant.
Topics: Diuretics, Osmotic; Drug Therapy, Combination; Enema; Female; Humans; Infant, Newborn; Infant, Prema | 2002 |
EFFECT OF A SMALL, CIRCUMSCRIBED HEPATIC NECROSIS ON SERUM AND HEPATIC ENZYME ACTIVITIES.
Topics: Alanine Transaminase; Angiography; Animals; Aspartate Aminotransferases; Clinical Enzyme Tests; Diat | 1963 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-2003. A 79-year-old man with coronary artery disease, peripheral vascular disease, end-stage renal disease, and abdominal pain and distention.
Topics: Abdominal Pain; Aged; Aortography; Cation Exchange Resins; Colon; Coronary Artery Disease; Diagnosis | 2003 |
Morphological and X-ray microanalytical changes in mammalian tissue after overhydration with irrigating fluids.
Topics: Animals; Brain; Chlorine; Diuretics, Osmotic; Drug Synergism; Electrocardiography; Electron Probe Mi | 1996 |
Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition.
Topics: Adult; Aged; Cation Exchange Resins; Child, Preschool; Cholestyramine Resin; Crystallization; Digest | 1997 |
Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients.
Topics: Aged; Cation Exchange Resins; Colon; Diuretics, Osmotic; Drug Therapy, Combination; Fatal Outcome; F | 1997 |
[Polystyrene sodium sulfonate enema: with or without sorbitol?].
Topics: Administration, Oral; Enema; Humans; Intestinal Mucosa; Kidney Failure, Chronic; Necrosis; Polystyre | 1999 |
Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol.
Topics: Abdomen, Acute; Administration, Oral; Administration, Rectal; Cathartics; Cation Exchange Resins; Co | 2000 |
Suppression of apoptotic and necrotic cell death by poliovirus.
Topics: Apoptosis; Cell Death; Cell Line; Eukaryotic Cells; Humans; Necrosis; Poliovirus; Proviruses; Sodium | 2001 |
Effects of some water-soluble contrast media on the colonic mucosa.
Topics: Animals; Barium Sulfate; Colon; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Intestinal Mucos | 1976 |
Amelioration of dermal lesions in streptozotocin-induced diabetic rats by aminoguanidine.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamid | 1992 |
Sodium polystyrene-sorbitol enemas.
Topics: Colon; Enema; Humans; Necrosis; Polystyrenes; Resins, Synthetic; Sorbitol | 1990 |
Colonic necrosis with Kayexalate-sorbitol enemas after renal transplantation.
Topics: Cation Exchange Resins; Colon; Enema; Humans; Hyperkalemia; Ion Exchange Resins; Kidney Transplantat | 1989 |
Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis.
Topics: Adolescent; Adult; Animals; Colon; Enema; Female; Humans; Hyperkalemia; Male; Middle Aged; Necrosis; | 1987 |
[Histochemical studies of the extension of necrosis following temporary regional myocardial ischemis in pigs (author's transl)].
Topics: Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Cineradiography; Coronary Disease; He | 1974 |
Hepatic function tests.
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Alkaline Phosphatase; Aminopeptidases; Antibodies; As | 1974 |
The effect of chloroform on the liver and the activity of serum enzymes in the horse.
Topics: Adenosine Triphosphatases; Animals; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced L | 1969 |
[Influence of surgical diseases and surgical interventions on the activity of GOT, GPT, SODH and AP enzymes in the blood serum of the cattle].
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Alkaline Phosphatase; Animals; Aspartate Aminotransfe | 1971 |
[Plasma enzyme activities and morphology of the myocardium following acute experimental coronary occlusion in relation to the spontanous collateral vessels of the heart].
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Collateral Circ | 1972 |
[Fatal liver dystrophy in 3 siblings with hereditary fructose intolerance after long-lasting infusion with sorbitol solutions].
Topics: Autopsy; Carbohydrate Metabolism, Inborn Errors; Chemical and Drug Induced Liver Injury; Fatty Liver | 1969 |
[Animal experiment studies on influencing the effect of a temporary coronary artery occlusion on the myocardium].
Topics: Animals; Blood Pressure; Cats; Coronary Vessels; Cortisone; Dextrans; Electrocardiography; Hydrogen- | 1969 |