Page last updated: 2024-11-06

sorbitol and Myocardial Ischemia

sorbitol has been researched along with Myocardial Ischemia in 5 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"This study investigated whether aldose reductase (AR) inhibition with zopolrestat, either alone or in combination with an adenosine A(3)-receptor agonist (CB-MECA), reduced myocardial ischemic injury in rabbit hearts subjected to 30 min of regional ischemia and 120 min of reperfusion."1.31Aldose reductase inhibition alone or combined with an adenosine A(3) agonist reduces ischemic myocardial injury. ( Ellery, CA; Knight, DR; MacAndrew, JT; Magee, WP; Oates, PJ; Smith, AH; Tracey, WR, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zweier, JL1
Wang, P1
Kuppusamy, P1
Ramasamy, R2
Oates, PJ2
Schaefer, S2
Trueblood, N1
Tracey, WR1
Magee, WP1
Ellery, CA1
MacAndrew, JT1
Smith, AH1
Knight, DR1
Lecour, S1
Maupoil, V1
Zeller, M1
Laubriet, A1
Briot, T1
Rochette, L1

Other Studies

5 other studies available for sorbitol and Myocardial Ischemia

ArticleYear
Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy.
    The Journal of biological chemistry, 1995, Jan-06, Volume: 270, Issue:1

    Topics: Animals; Arginine; Chelating Agents; Coronary Vessels; Electron Spin Resonance Spectroscopy; Female;

1995
Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury.
    Diabetes, 1997, Volume: 46, Issue:2

    Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Benzothiazoles; Blood Glucose; Diabetes Mellitu

1997
Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Aldehyde Reductase; Animals; Benzothiazoles; Cytosol; Diabetes Mellitus, Type 1; Enzyme Inhibitors;

1998
Aldose reductase inhibition alone or combined with an adenosine A(3) agonist reduces ischemic myocardial injury.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Adenosine; Aldehyde Reductase; Animals; Benzothiazoles; Dose-Response Relationship, Drug; Enzyme Inh

2000
Levels of nitric oxide in the heart after experimental myocardial ischemia.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:1

    Topics: Animals; Chelating Agents; Coronary Vessels; Electron Spin Resonance Spectroscopy; Guanidines; Hemog

2001