sorbitol has been researched along with Multiple Sclerosis in 6 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gadolinium DTPA is a paramagnetic contrast agent that does not cross an intact blood-brain barrier." | 5.27 | Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging. ( Atlas, SW; Galetta, S; Gonzalez-Scarano, F; Grossman, RI; Silberberg, DH, 1987) |
| "Thirteen patients with definite multiple sclerosis (MS), studied 16-24 months previously with magnetic resonance (MR) imaging with and without enhancement by intravenously administered gadolinium diethylenetriaminepentaacetic acid (DTPA) dimeglumine, were reexamined with a similar protocol." | 3.67 | Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. ( Braffman, BH; Brorson, JR; Goldberg, HI; Gonzalez-Scarano, F; Grossman, RI; Silberberg, DH, 1988) |
| "Gadolinium DTPA is a paramagnetic contrast agent that does not cross an intact blood-brain barrier." | 1.27 | Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging. ( Atlas, SW; Galetta, S; Gonzalez-Scarano, F; Grossman, RI; Silberberg, DH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Regenold, WT | 1 |
| Phatak, P | 1 |
| Makley, MJ | 1 |
| Stone, RD | 1 |
| Kling, MA | 1 |
| Smith, SL | 1 |
| Novotný, M | 1 |
| Karmen, A | 1 |
| Grossman, RI | 2 |
| Braffman, BH | 1 |
| Brorson, JR | 1 |
| Goldberg, HI | 1 |
| Silberberg, DH | 2 |
| Gonzalez-Scarano, F | 2 |
| Galetta, S | 1 |
| Atlas, SW | 1 |
| Gusev, EI | 1 |
| Karneev, AN | 1 |
| Ivanokov, AN | 1 |
| Gürtler, J | 1 |
6 other studies available for sorbitol and Multiple Sclerosis
| Article | Year |
|---|---|
Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression.
Topics: Adult; Analysis of Variance; Disease Progression; Female; Fructose; Glucose; Humans; Lactic Acid; Ma | 2008 |
Elevation of certain polyols in the cerebrospinal fluid of patients with multiple sclerosis.
Topics: Chromatography, Ion Exchange; Fructose; Humans; Multiple Sclerosis; Sorbitol | 1984 |
Multiple sclerosis: serial study of gadolinium-enhanced MR imaging.
Topics: Adult; Aged; Blood-Brain Barrier; Brain; Contrast Media; Drug Combinations; Female; Gadolinium DTPA; | 1988 |
Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging.
Topics: Adult; Aged; Brain; Contrast Media; Drug Combinations; Female; Gadolinium; Gadolinium DTPA; Humans; | 1987 |
[Use of polyamine in the complex treatment of multiple sclerosis].
Topics: Adult; Amino Acids; Drug Therapy, Combination; Female; Glucose; Humans; Male; Middle Aged; Multiple | 1985 |
[Treatment of constipation in multiple sclerosis].
Topics: Constipation; Enema; Humans; Multiple Sclerosis; Sorbitol | 1967 |