Page last updated: 2024-11-06

sorbitol and Malabsorption Syndromes

sorbitol has been researched along with Malabsorption Syndromes in 47 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Malabsorption Syndromes: General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.

Research Excerpts

ExcerptRelevanceReference
"Small intestinal bacterial overgrowth and sugar malabsorption (lactose, fructose, sorbitol) may play a role in irritable bowel syndrome."7.73Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth. ( Cammarota, G; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Lauritano, EC; Lupascu, A; Nucera, G; Pola, P; Santoliquido, A; Tondi, P, 2005)
"To study the possible causes of sorbitol (S)-based diarrhea and its mechanism of reduction by rice gruel (RG) in cecectomized rats."7.73Sorbitol-based osmotic diarrhea: possible causes and mechanism of prevention investigated in rats. ( Islam, MS; Sakaguchi, E, 2006)
"Small intestinal bacterial overgrowth and sugar malabsorption (lactose, fructose, sorbitol) may play a role in irritable bowel syndrome."3.73Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth. ( Cammarota, G; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Lauritano, EC; Lupascu, A; Nucera, G; Pola, P; Santoliquido, A; Tondi, P, 2005)
"To study the possible causes of sorbitol (S)-based diarrhea and its mechanism of reduction by rice gruel (RG) in cecectomized rats."3.73Sorbitol-based osmotic diarrhea: possible causes and mechanism of prevention investigated in rats. ( Islam, MS; Sakaguchi, E, 2006)
"In 25 patients with untreated celiac disease and 23 sex- and age-matched healthy volunteers, breath H(2) excretion was measured after ingestion of a 250-ml solution containing sorbitol, a poorly absorbed alcohol sugar."3.72Mixing of the intestinal content and variations of fermentation capacity do not affect the results of hydrogen breath test. ( Corazza, GR; Di Stefano, M; Malservisi, S; Miceli, E; Missanelli, A; Strocchi, A, 2003)
"We performed breath hydrogen analyses in 13 healthy children (9 to 36 months of age) and seven children (14 to 27 months of age) with chronic nonspecific diarrhea after they had ingested pear, grape, and apple juices and a 2% sorbitol solution."3.67Carbohydrate malabsorption following fruit juice ingestion in young children. ( Etienne, NL; Hyams, JS; Leichtner, AM; Theuer, RC, 1988)
" The bioavailability of ADiSP and a native (unmodified) starch was evaluated in 20 normal infants and 21 toddlers aged 8-24 mo with chronic non-specific diarrhea."2.70Malabsorption of modified food starch (acetylated distarch phosphate) in normal infants and in 8-24-month-old toddlers with non-specific diarrhea, as influenced by sorbitol and fructose. ( Lebenthal, A; Lebenthal, E; Lebenthal-Bendor, Y; Tabi, I; Theuer, RC, 2001)
"To determine whether infantile colic (IC) is associated with malabsorption of carbohydrates present in fruit juices."2.70Association between infantile colic and carbohydrate malabsorption from fruit juices in infancy. ( Cedillo, M; Duro, D; Lifshitz, F; Rising, R, 2002)
"While lactose malabsorption is a well-investigated condition, few epidemiologic data are available for fructose and sorbitol malabsorption."1.42Carbohydrate Malabsorption and Putative Carbohydrate-Specific Small Intestinal Bacterial Overgrowth: Prevalence and Diagnostic Overlap Observed in an Austrian Outpatient Center. ( Enko, D; Halwachs-Baumann, G; Kimbacher, C; Kriegshäuser, G; Mangge, H; Stolba, R, 2015)
"In preliminary studies feeding the poorly absorbed carbohydrate sorbitol at 2."1.29Determination of lactose and xylose malabsorption in preruminant diarrheic calves. ( Hamilton, D; Nappert, G; Naylor, JM; Petrie, L, 1993)
" The possible importance of alpha-tocopherol in preventing the toxic effect of iron on the apparently very sensitive myocardium after parenteral iron to patients with severe malabsorption syndrome is discussed."1.26Alpha-tocopherol and cardiac toxicity of iron. ( Lindvall, S; Rydén, L; Smedgärd, P; Swedberg, B, 1980)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199010 (21.28)18.7374
1990's14 (29.79)18.2507
2000's15 (31.91)29.6817
2010's8 (17.02)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klek, S1
Chambrier, C1
Cooper, SC1
Gabe, S1
Kunecki, M1
Pironi, L1
Rahman, F1
Sobocki, J1
Szczepanek, K1
Wanten, G1
Lincke, N1
Glotzbach, B1
Forbes, A1
Perets, TT1
Hamouda, D1
Layfer, O1
Ashorov, O1
Boltin, D1
Levy, S1
Niv, Y1
Dickman, R1
Klee, B1
Barske, O1
Mack, A1
Thoeringer, CK1
Haller, B1
Becker, V1
Nennstiel, S1
Montalto, M1
Gallo, A1
Ojetti, V1
Gasbarrini, A2
Däbritz, J1
Mühlbauer, M1
Domagk, D1
Voos, N1
Henneböhl, G1
Siemer, ML1
Foell, D1
Enko, D1
Kriegshäuser, G1
Kimbacher, C1
Stolba, R1
Mangge, H1
Halwachs-Baumann, G1
Heckl, S1
Reiners, C1
Buck, AK1
Schäfer, A1
Dick, A1
Scheurlen, M1
Valeur, J1
Øines, E1
Morken, MH1
Holst, JJ1
Berstad, A1
Fernández-Bañares, F4
Esteve, M2
Viver, JM1
Born, P4
Di Stefano, M2
Miceli, E2
Malservisi, S1
Missanelli, A2
Strocchi, A2
Corazza, GR3
Valois, S1
Rising, R3
Duro, D2
Cole, C1
Cedillo, M2
Lifshitz, F4
Mishkin, DS1
Mishkin, S2
Nucera, G1
Gabrielli, M1
Lupascu, A1
Lauritano, EC1
Santoliquido, A1
Cremonini, F1
Cammarota, G1
Tondi, P1
Pola, P1
Gasbarrini, G2
Rosinach, M1
Forné, M1
Espinós, JC1
Maria Viver, J1
Madsen, JL1
Linnet, J1
Rumessen, JJ4
Islam, MS1
Sakaguchi, E1
Hyams, JS2
Lindvall, S1
Rydén, L1
Smedgärd, P1
Swedberg, B1
Vernia, P1
Frandina, C1
Bilotta, T1
Ricciardi, MR1
Villotti, G1
Fallucca, F1
Zech, J1
Stark, M1
Classen, M1
Lorenz, R1
Esteve-Pardo, M2
de Leon, R2
Humbert, P2
Cabré, E1
Llovet, JM2
Gassull, MA2
Nappert, G1
Hamilton, D1
Petrie, L1
Naylor, JM1
Hoekstra, JH2
van Kempen, AA1
Kneepkens, CM2
Mishkin, D1
Sablauskas, L1
Yalovsky, M1
Gudmand-Høyer, E3
Cole, CR1
Goldstein, R1
Braverman, D1
Stankiewicz, H1
Ladas, SD1
Grammenos, I1
Tassios, PS1
Raptis, SA1
Lebenthal-Bendor, Y1
Theuer, RC2
Lebenthal, A1
Tabi, I1
Lebenthal, E2
Ament, ME1
Kleinman, RE1
Klish, W1
Perman, J1
Udall, JN1
Barina, W1
Vierling, T1
Nelis, GF1
Vermeeren, MA1
Jansen, W1
Lembcke, B1
Rossi, R1
Sirola, D1
Etienne, NL1
Leichtner, AM1
Jain, NK1
Patel, VP1
Pitchumoni, CS1
Coyne, MJ1
Rodriguez, H1
Gligore, V1
Fekete, T1
Stefenelli, N1
Klotz, H1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Controlled, Double-blind, Multicenter Clinical Trial on Home Parenteral Nutrition Using an Omega-3 Fatty Acid Enriched MCT/LCT Lipid Emulsion[NCT03282955]Phase 474 participants (Actual)Interventional2018-01-08Completed
Effects of FODMAPs (Fermentable Oligo-, Di-, and Mono-saccharides, And Polyols) on Small Bowel Water Content: an MRI Study[NCT01459406]17 participants (Actual)Interventional2011-10-31Completed
Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children[NCT02016703]185 participants (Actual)Interventional2006-03-31Completed
Fructose and Fructans and Irritable Bowel Syndrome: MRI Study of Underlying Mechanisms[NCT01776853]69 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for sorbitol and Malabsorption Syndromes

ArticleYear
Fructose, trehalose and sorbitol malabsorption.
    European review for medical and pharmacological sciences, 2013, Volume: 17 Suppl 2

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Diarrhea; Fructose Intolerance; Humans; Intest

2013
Fructose-sorbitol malabsorption.
    Current gastroenterology reports, 2009, Volume: 11, Issue:5

    Topics: Breath Tests; Evidence-Based Medicine; Fructose; Fructose Intolerance; Humans; Intestinal Absorption

2009
The clinical impact of carbohydrate malabsorption.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2011, Volume: 12, Issue:1

    Topics: Diagnosis, Differential; Dietary Carbohydrates; Fructose Intolerance; Humans; Lactose Intolerance; M

2011
Carbohydrate malabsorption in patients with non-specific abdominal complaints.
    World journal of gastroenterology, 2007, Nov-21, Volume: 13, Issue:43

    Topics: Carbohydrate Metabolism; Fructose; Humans; Intestinal Absorption; Intestinal Diseases; Malabsorption

2007
Role of juice carbohydrate malabsorption in chronic nonspecific diarrhea in children.
    The Journal of pediatrics, 1992, Volume: 120, Issue:5

    Topics: Beverages; Child, Preschool; Chronic Disease; Diarrhea; Diarrhea, Infantile; Dietary Carbohydrates;

1992

Trials

8 trials available for sorbitol and Malabsorption Syndromes

ArticleYear
Home parenteral nutrition with an omega-3-fatty-acid-enriched MCT/LCT lipid emulsion in patients with chronic intestinal failure (the HOME study): study protocol for a randomized, controlled, multicenter, international clinical trial.
    Trials, 2019, Dec-30, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Bilir

2019
Effect of nonabsorbed amounts of a fructose-sorbitol mixture on small intestinal transit in healthy volunteers.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:1

    Topics: Adult; Breath Tests; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug

2006
[Carbohydrate substitutes: comparative study of intestinal absorption of fructose, sorbitol and xylitol].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Nov-15, Volume: 89, Issue:11

    Topics: Adult; Breath Tests; Double-Blind Method; Female; Fructose; Humans; Intestinal Absorption; Lactulose

1994
Fructose and sorbitol malabsorption in ambulatory patients with functional dyspepsia: comparison with lactose maldigestion/malabsorption.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:12

    Topics: Breath Tests; Dyspepsia; Ethnicity; Female; Fructose; Gastrointestinal Transit; Humans; Intestinal A

1997
Fructans of chicory: intestinal transport and fermentation of different chain lengths and relation to fructose and sorbitol malabsorption.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:2

    Topics: Acetates; Adolescent; Adult; Biological Transport; Blood Glucose; Cross-Over Studies; Female; Fermen

1998
Consequences of incomplete carbohydrate absorption from fruit juice consumption in infants.
    Archives of pediatrics & adolescent medicine, 1999, Volume: 153, Issue:10

    Topics: Analysis of Variance; Beverages; Breath Tests; Carbon Dioxide; Double-Blind Method; Fruit; Humans; I

1999
Malabsorption of modified food starch (acetylated distarch phosphate) in normal infants and in 8-24-month-old toddlers with non-specific diarrhea, as influenced by sorbitol and fructose.
    Acta paediatrica (Oslo, Norway : 1992), 2001, Volume: 90, Issue:12

    Topics: Acetylation; Child, Preschool; Diarrhea, Infantile; Female; Flavoring Agents; Food Preservatives; Fr

2001
Association between infantile colic and carbohydrate malabsorption from fruit juices in infancy.
    Pediatrics, 2002, Volume: 109, Issue:5

    Topics: Analysis of Variance; Beverages; Breath Tests; Carbohydrate Metabolism; Colic; Crying; Double-Blind

2002

Other Studies

34 other studies available for sorbitol and Malabsorption Syndromes

ArticleYear
Small Intestinal Bacterial Overgrowth May Increase the Likelihood of Lactose and Sorbitol but not Fructose Intolerance False Positive Diagnosis.
    Annals of clinical and laboratory science, 2017, Volume: 47, Issue:4

    Topics: Bacterial Infections; Breath Tests; Diagnostic Errors; False Positive Reactions; Female; Follow-Up S

2017
Sorbitol malabsorption in patients with abdominal discomfort.
    Minerva gastroenterologica e dietologica, 2018, Volume: 64, Issue:2

    Topics: Abdominal Pain; Breath Tests; Diagnostic Self Evaluation; Female; Humans; Malabsorption Syndromes; M

2018
Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption.
    BMC pediatrics, 2014, Feb-27, Volume: 14

    Topics: Adolescent; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Female; F

2014
Carbohydrate Malabsorption and Putative Carbohydrate-Specific Small Intestinal Bacterial Overgrowth: Prevalence and Diagnostic Overlap Observed in an Austrian Outpatient Center.
    Digestion, 2015, Volume: 92, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Austria; Blind Loop Syndrome

2015
Evidence of impaired carbohydrate assimilation in euthyroid patients with Hashimoto's thyroiditis.
    European journal of clinical nutrition, 2016, Volume: 70, Issue:2

    Topics: Adult; Blood Glucose; Breath Tests; Case-Control Studies; Diet Records; Dietary Carbohydrates; Femal

2016
Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.
    Scandinavian journal of gastroenterology, 2008, Volume: 43, Issue:10

    Topics: Adult; Breath Tests; Case-Control Studies; Female; Food Hypersensitivity; Fructose; Glucagon-Like Pe

2008
Mixing of the intestinal content and variations of fermentation capacity do not affect the results of hydrogen breath test.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:7

    Topics: Adult; Artifacts; Breath Tests; Carbohydrate Metabolism; Case-Control Studies; Celiac Disease; Colon

2003
Carbohydrate malabsorption may increase daily energy requirements in infants.
    Nutrition (Burbank, Los Angeles County, Calif.), 2003, Volume: 19, Issue:10

    Topics: Basal Metabolism; Beverages; Breath Tests; Child Development; Dietary Carbohydrates; Energy Intake;

2003
Sorbital H2 breath testing when screening for malabsorption/ intolerance and untreated celiac disease: understanding the dose and concentration issues.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:6

    Topics: Breath Tests; Case-Control Studies; Celiac Disease; Dose-Response Relationship, Drug; Female; Humans

2004
Sorbitol malabsorption: further explanations are needed.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:4

    Topics: Administration, Oral; Breath Tests; Celiac Disease; Dietary Carbohydrates; Dose-Response Relationshi

2005
Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth.
    Alimentary pharmacology & therapeutics, 2005, Jun-01, Volume: 21, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Breath Tests; Diagnostic Errors; Drug Therapy, C

2005
Sugar malabsorption in functional abdominal bloating: a pilot study on the long-term effect of dietary treatment.
    Clinical nutrition (Edinburgh, Scotland), 2006, Volume: 25, Issue:5

    Topics: Breath Tests; Colonic Diseases, Functional; Dietary Carbohydrates; Female; Flatulence; Fructose; Hum

2006
Sorbitol-based osmotic diarrhea: possible causes and mechanism of prevention investigated in rats.
    World journal of gastroenterology, 2006, Dec-21, Volume: 12, Issue:47

    Topics: Animal Feed; Animals; Cathartics; Diarrhea; Disease Models, Animal; Malabsorption Syndromes; Male; O

2006
Chronic abdominal pain caused by sorbitol malabsorption.
    The Journal of pediatrics, 1982, Volume: 100, Issue:5

    Topics: Abdomen; Child, Preschool; Chronic Disease; Female; Humans; Malabsorption Syndromes; Pain; Sorbitol

1982
Alpha-tocopherol and cardiac toxicity of iron.
    Scandinavian journal of haematology, 1980, Volume: 25, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Citrates; Citric Acid; Drug Combinations; Electrocardiography; Ferric Co

1980
Sorbitol malabsorption and nonspecific abdominal symptoms in type II diabetes.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:6

    Topics: Abdomen; Aged; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Malabsor

1995
Sugar malabsorption in functional bowel disease: clinical implications.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:12

    Topics: Adult; Breath Tests; Colonic Diseases, Functional; Diagnosis, Differential; Dietary Carbohydrates; F

1993
Determination of lactose and xylose malabsorption in preruminant diarrheic calves.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1993, Volume: 57, Issue:3

    Topics: Animals; Blood Glucose; Breath Tests; Cattle; Cattle Diseases; Coronaviridae Infections; Cryptospori

1993
Apple juice malabsorption: fructose or sorbitol?
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 16, Issue:1

    Topics: Adult; Breath Tests; Child; Child, Preschool; Female; Fructose; Fruit; Humans; Hydrogen; Infant; Mal

1993
Fruit juice and chronic nonspecific diarrhea.
    The Journal of pediatrics, 1993, Volume: 122, Issue:3

    Topics: Breath Tests; Child; Child, Preschool; Chronic Disease; Diarrhea; Fructose; Fruit; Humans; Hydrogen;

1993
Carbohydrate malabsorption and the effect of dietary restriction on symptoms of irritable bowel syndrome and functional bowel complaints.
    The Israel Medical Association journal : IMAJ, 2000, Volume: 2, Issue:8

    Topics: Adult; Colonic Diseases, Functional; Female; Fructose Intolerance; Humans; Lactose Intolerance; Mala

2000
Coincidental malabsorption of lactose, fructose, and sorbitol ingested at low doses is not common in normal adults.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:12

    Topics: Adult; Breath Tests; Female; Fructose; Fructose Intolerance; Humans; Hydrogen; Lactose; Lactose Into

2000
Functional bowel disease: the role of fructose and sorbitol.
    Gastroenterology, 1991, Volume: 101, Issue:5

    Topics: Colonic Diseases, Functional; Fructose; Humans; Intestinal Absorption; Malabsorption Syndromes; Sorb

1991
Role of fructose-sorbitol malabsorption in the irritable bowel syndrome.
    Gastroenterology, 1991, Volume: 101, Issue:5

    Topics: Adult; Aged; Colonic Diseases, Functional; Female; Fructose; Humans; Intestinal Absorption; Malabsor

1991
[Fructose and sorbitol malabsorption].
    Deutsche medizinische Wochenschrift (1946), 1990, Apr-13, Volume: 115, Issue:15

    Topics: Fructose; Humans; Malabsorption Syndromes; Sorbitol; Turkey

1990
Role of fructose-sorbitol malabsorption in the irritable bowel syndrome.
    Gastroenterology, 1990, Volume: 99, Issue:4

    Topics: Adult; Breath Tests; Colonic Diseases, Functional; Female; Fructose; Humans; Hydrogen; Intestinal Ab

1990
[Carbohydrate malabsorption (fructose, sorbitol) and functional intestinal disorders].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:3

    Topics: Colonic Diseases, Functional; Fructose Intolerance; Fructose Metabolism, Inborn Errors; Humans; Mala

1989
Sorbitol malabsorption in normal volunteers and in patients with coeliac disease.
    Gut, 1988, Volume: 29, Issue:1

    Topics: Adult; Breath Tests; Celiac Disease; Female; Humans; Intestinal Absorption; Malabsorption Syndromes;

1988
Carbohydrate malabsorption following fruit juice ingestion in young children.
    Pediatrics, 1988, Volume: 82, Issue:1

    Topics: Breath Tests; Carbohydrate Metabolism; Carbohydrates; Child, Preschool; Chronic Disease; Diarrhea; F

1988
Malabsorption of fructose-sorbitol mixtures. Interactions causing abdominal distress.
    Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:4

    Topics: Adult; Breath Tests; Deuterium; Drug Combinations; Drug Interactions; Fructose; Gastrointestinal Dis

1987
Sorbitol intolerance in adults. Prevalence and pathogenesis on two continents.
    Journal of clinical gastroenterology, 1987, Volume: 9, Issue:3

    Topics: Adult; Black People; Gastrointestinal Motility; Humans; India; Intestinal Absorption; Malabsorption

1987
Carbohydrate malabsorption in black and Hispanic dialysis patients.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:8

    Topics: Adult; Aged; Black or African American; Breath Tests; Dietary Carbohydrates; Female; Fructose; Hispa

1986
[Current data on diagnosis and treatment of denutrition states].
    Medicina interna, 1972, Volume: 24, Issue:8

    Topics: Adrenal Cortex Hormones; Deficiency Diseases; Diagnosis, Differential; Diet Therapy; Fructose; Gluco

1972
[Use of isosorbide for an absorption test].
    Munchener medizinische Wochenschrift (1950), 1973, Jan-26, Volume: 115, Issue:4

    Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Blood Volume; Carbohydrate Metabolism; Celiac Disease;

1973