sorbitol has been researched along with Innate Inflammatory Response in 14 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of the free radical scavenger 2,4-tetra-O-methyl-furfurylidene-sorbitol (MSF) on the carrageenan-induced hind-paw inflammation in rats as well as its influence on the anti-inflammatory and toxic activities of indomethacin is evaluated in comparison with thiola, thioctic acid, silymarin, reduced glutathione and propylgallate." | 7.66 | Influence of 2,4-tetra-O-methyl-furfurylidene-sorbitol (MSF) on carrageenan-induced inflammation and anti-inflammatory and toxic effects of indomethacin in rats. ( Baggio, G; Poggioli, R; Zanoli, P, 1982) |
| "Habitual xylitol gum chewing may reduce gingival inflammation." | 5.22 | Effects of sugar-free polyol chewing gums on gingival inflammation: a systematic review. ( Gursoy, UK; Pienihäkkinen, K; Söderling, E, 2022) |
| " This indicates the following metabolic derangements in DME: (a) a higher amount of oxidized fatty acids but a lower amount of endogenous antioxidants (oxidative stress); (b) higher levels of β-glucose and homocysteine but a lower level of sorbitol (hyperglycemia); (c) a higher amount of prostaglandin metabolites (inflammation); (d) higher amounts of acylcarnitines, odd-numbered fatty acids, and 7,8-diaminononanoate (respiration deterioration); (e) a higher amount of neurotransmitter metabolites and homovanillic acid (neuronal damage); (f) a lower amount of extracellular matrix (ECM) constituents (ECM deterioration); and (g) a higher amount of di-amino peptides (microvascular damage)." | 4.12 | Untargeted metabolomic analysis of aqueous humor in diabetic macular edema. ( Bakthavatsalam, M; Brelen, ME; Chan, KP; Chan, TI; Chu, KO; Pang, CP; Wang, CC; Yip, YW, 2022) |
| " Uveitis is a disease of the eye associated with chronic inflammation." | 3.79 | Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. ( Chang, KC; Enzsöly, A; LaBarbera, DV; Laffin, B; Németh, J; Petrash, JM; Ponder, J, 2013) |
| "The influence of the free radical scavenger 2,4-tetra-O-methyl-furfurylidene-sorbitol (MSF) on the carrageenan-induced hind-paw inflammation in rats as well as its influence on the anti-inflammatory and toxic activities of indomethacin is evaluated in comparison with thiola, thioctic acid, silymarin, reduced glutathione and propylgallate." | 3.66 | Influence of 2,4-tetra-O-methyl-furfurylidene-sorbitol (MSF) on carrageenan-induced inflammation and anti-inflammatory and toxic effects of indomethacin in rats. ( Baggio, G; Poggioli, R; Zanoli, P, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Söderling, E | 1 |
| Pienihäkkinen, K | 1 |
| Gursoy, UK | 1 |
| Chu, KO | 1 |
| Chan, TI | 1 |
| Chan, KP | 1 |
| Yip, YW | 1 |
| Bakthavatsalam, M | 1 |
| Wang, CC | 1 |
| Pang, CP | 1 |
| Brelen, ME | 1 |
| Papachristoforou, E | 1 |
| Lambadiari, V | 1 |
| Maratou, E | 1 |
| Makrilakis, K | 1 |
| Nakatsu, Y | 1 |
| Kokubo, H | 1 |
| Bumdelger, B | 1 |
| Yoshizumi, M | 1 |
| Yamamotoya, T | 1 |
| Matsunaga, Y | 1 |
| Ueda, K | 1 |
| Inoue, Y | 1 |
| Inoue, MK | 1 |
| Fujishiro, M | 1 |
| Kushiyama, A | 1 |
| Ono, H | 1 |
| Sakoda, H | 1 |
| Asano, T | 1 |
| Ahmadyan, S | 1 |
| Kabiri, M | 1 |
| Tasharofi, N | 1 |
| Hosseinzadeh, S | 1 |
| Kehtari, M | 1 |
| Hajari Zadeh, A | 1 |
| Soleimani, M | 1 |
| Farazmand, A | 1 |
| Hanaee-Ahvaz, H | 1 |
| Yang, S | 1 |
| Zhao, Y | 1 |
| Yu, J | 1 |
| Fan, Z | 1 |
| Gong, ST | 1 |
| Tang, H | 1 |
| Pan, L | 1 |
| Weinstein, EA | 1 |
| Ordonez, AA | 1 |
| DeMarco, VP | 1 |
| Murawski, AM | 1 |
| Pokkali, S | 1 |
| MacDonald, EM | 1 |
| Klunk, M | 1 |
| Mease, RC | 1 |
| Pomper, MG | 1 |
| Jain, SK | 1 |
| Ishibashi, Y | 1 |
| Matsui, T | 1 |
| Matsumoto, T | 1 |
| Kato, H | 1 |
| Yamagishi, S | 1 |
| Chang, KC | 1 |
| Laffin, B | 1 |
| Ponder, J | 1 |
| Enzsöly, A | 1 |
| Németh, J | 1 |
| LaBarbera, DV | 1 |
| Petrash, JM | 1 |
| Zanoli, P | 1 |
| Baggio, G | 1 |
| Poggioli, R | 1 |
| Smith, FW | 1 |
| Dendy, PP | 1 |
| Pocklington, T | 1 |
| Dawson, AA | 1 |
| Foster, MA | 1 |
| Mallard, JR | 1 |
| Nakagawa, H | 1 |
| Ikota, N | 1 |
| Ozawa, T | 1 |
| Kotake, Y | 1 |
| Ottlecz, A | 1 |
| Dekov, E | 1 |
| Koltai, M | 1 |
| Minker, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes[NCT05478707] | Phase 2 | 64 participants (Anticipated) | Interventional | 2023-10-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sorbitol and Innate Inflammatory Response
| Article | Year |
|---|---|
Effects of sugar-free polyol chewing gums on gingival inflammation: a systematic review.
Topics: Chewing Gum; Dental Plaque; Gingivitis; Humans; Inflammation; Prospective Studies; Sorbitol; Xylitol | 2022 |
Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathi | 2020 |
12 other studies available for sorbitol and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Untargeted metabolomic analysis of aqueous humor in diabetic macular edema.
Topics: Antioxidants; Aqueous Humor; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fatty Acids; Glucose; | 2022 |
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cytokines; Diabetes Mel | 2017 |
The osmolyte type affects cartilage associated pathologic marker expression during in vitro mesenchymal stem cell chondrogenesis under hypertonic conditions.
Topics: Adipose Tissue; Calcium; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chondrocytes; Ch | 2018 |
Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila.
Topics: Alarmins; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Animals, Genetically Modified; Carrier | 2019 |
Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography.
Topics: Animals; Anti-Infective Agents; Brain Neoplasms; Cell Line; Enterobacteriaceae Infections; Escherich | 2014 |
Ranirestat has a stronger inhibitory activity on aldose reductase and suppresses inflammatory reactions in high glucose-exposed endothelial cells.
Topics: Aldehyde Reductase; Anti-Inflammatory Agents; Cell Line, Tumor; Chromatography, Liquid; Dose-Respons | 2016 |
Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues.
Topics: Aldehyde Reductase; Animals; Apoptosis; Cells, Cultured; Eye; Hydrolyzable Tannins; Inflammation; In | 2013 |
Influence of 2,4-tetra-O-methyl-furfurylidene-sorbitol (MSF) on carrageenan-induced inflammation and anti-inflammatory and toxic effects of indomethacin in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Drug Synergism; Female; Free Radicals; Gastric Mucos | 1982 |
A preliminary investigation of 67Ga citrate distribution in hyperferraemic patients.
Topics: Citrates; Citric Acid; Drug Combinations; False Negative Reactions; False Positive Reactions; Ferric | 1980 |
Dose- and time-dependence of radiation-induced nitric oxide formation in mice as quantified with electron paramagnetic resonance.
Topics: Animals; Arginine; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Enzy | 2001 |
Anti-inflammatory activity of various agents producing hyperlipemia in rats.
Topics: Administration, Oral; Animals; Blood Vessels; Carrageenan; Dextrans; Dose-Response Relationship, Dru | 1974 |