sorbitol has been researched along with Hypoglycemia in 13 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peripheral hyperglycemia was associated with significant increases in brain sorbitol (7." | 3.74 | Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory. ( Chong, L; Diamond, DM; Hanna, S; Malone, JI; Mervis, RF; Park, CR; Saporta, S, 2008) |
| " Safety assessments included adverse events, laboratory tests and vital signs." | 2.87 | Efficacy and safety of luseogliflozin added to insulin therapy in Japanese patients with type 2 diabetes: a multicenter, 52-week, clinical study with a 16-week, double-blind period and a 36-week, open-label period. ( Fukatsu, A; Imazeki, H; Ochiai, H; Sakai, S; Sasaki, T; Seino, Y, 2018) |
| "A total of 18 Japanese patients with type 2 diabetes were randomized into two groups, in which patients first received luseogliflozin 2." | 2.82 | Sodium-glucose cotransporter 2 inhibitor luseogliflozin improves glycaemic control, assessed by continuous glucose monitoring, even on a low-carbohydrate diet. ( Nishimura, R; Omiya, H; Sakai, S; Samukawa, Y; Sugio, K; Ubukata, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Papachristoforou, E | 1 |
| Lambadiari, V | 1 |
| Maratou, E | 1 |
| Makrilakis, K | 1 |
| Seino, Y | 2 |
| Sasaki, T | 1 |
| Fukatsu, A | 1 |
| Imazeki, H | 1 |
| Ochiai, H | 1 |
| Sakai, S | 3 |
| Nishimura, R | 2 |
| Osonoi, T | 1 |
| Kanada, S | 2 |
| Jinnouchi, H | 1 |
| Sugio, K | 2 |
| Omiya, H | 2 |
| Ubukata, M | 2 |
| Samukawa, Y | 2 |
| Yabe, D | 1 |
| Iwasaki, M | 1 |
| Kuwata, H | 1 |
| Haraguchi, T | 1 |
| Hamamoto, Y | 1 |
| Kurose, T | 1 |
| Sumita, K | 1 |
| Yamazato, H | 1 |
| Malone, JI | 1 |
| Hanna, S | 1 |
| Saporta, S | 1 |
| Mervis, RF | 1 |
| Park, CR | 1 |
| Chong, L | 1 |
| Diamond, DM | 1 |
| Ogawa, A | 1 |
| Miyamae, Y | 1 |
| Honma, A | 1 |
| Koyama, T | 1 |
| Yazawa, K | 1 |
| Shigemori, H | 1 |
| FREINKEL, N | 1 |
| COHEN, AK | 1 |
| ARKY, RA | 1 |
| FOSTER, AE | 1 |
| Giddings, AE | 1 |
| Rowlands, BJ | 1 |
| Mangnall, D | 1 |
| Clark, RG | 1 |
| Mann, J | 1 |
| Rett, K | 1 |
| Wicklmayr, M | 1 |
| Schwiegelshohn, B | 1 |
| Mickan, C | 1 |
| Dietze, G | 1 |
| Mehnert, H | 1 |
| Fiedler, H | 1 |
| Harries, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes[NCT05478707] | Phase 2 | 64 participants (Anticipated) | Interventional | 2023-10-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sorbitol and Hypoglycemia
| Article | Year |
|---|---|
Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathi | 2020 |
Dietary advice for diabetics: a perspective from the United Kingdom.
Topics: Blood Glucose; Diabetes Mellitus; Diabetic Angiopathies; Diet, Sodium-Restricted; Dietary Carbohydra | 1986 |
5 trials available for sorbitol and Hypoglycemia
6 other studies available for sorbitol and Hypoglycemia
| Article | Year |
|---|---|
Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Dendrites; Dendritic Spines; Diabetes Mellitus, Experimen | 2008 |
Pycnalin, a new α-glucosidase inhibitor from Acer pycnanthum.
Topics: Acer; Biphenyl Compounds; Deoxyglucose; Enzyme Inhibitors; Free Radical Scavengers; Gallic Acid; Gly | 2011 |
ALCOHOL HYPOGLYCEMIA. II. A POSTULATED MECHANISM OF ACTION BASED ON EXPERIMENTS WITH RAT LIVER SLICES.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoradiography; Carbohydrate Metabolism; Carbon Dioxide; Carbo | 1965 |
Plasma insulin and surgery. II. Later changes and the effect of intravenous carbohydrates.
Topics: Abdomen; Carbohydrates; Glucose; Humans; Hypoglycemia; Insulin; Insulin Secretion; Male; Parenteral | 1977 |
[Studies on the toxicity of copper disodium ethylenediamine tetra-acetate].
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Calcium; Copper | 1969 |
Intravenous feeding in infants.
Topics: Acidosis; Amino Acids; Catheterization; Emulsions; Ethanol; Fats; Fructose; Glucose; Heart Failure; | 1971 |