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sorbitol and Hypernatremia

sorbitol has been researched along with Hypernatremia in 14 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Hypernatremia: Excessive amount of sodium in the blood. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."7.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
"To clarify the role of the sugar polyols, sorbitol and myo-inositol, in cerebral cell volume regulation, we studied the effect of sorbinil, an inhibitor of aldose and aldehyde reductase, on the size of the cerebral water compartments in rats with hypernatremia, hyponatremia and normonatremia."3.68The role of polyols in cerebral cell volume regulation in hypernatremic and hyponatremic states. ( Futterweit, S; Hammer, E; Oates, P; Siegel, TW; Trachtman, H, 1991)
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."3.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
"In posthaemorrhagic and postmeningitic hydrocephalus valuable time was gained before shunt therapy until the infant and his CSF were fit for operation."2.64Isosorbide in treatment of infantile hydrocephalus. ( Lorber, J, 1975)
"The treatment of cerebral edema must be directed towards improving the volume regulation of the brain cell which is disturbed due to reduced blood flow and hypoxia and towards restoring the disturbed function of the blood-brain barrier."1.25[Osmo-oncotherapy in brain edema]. ( Gofferje, H; Landgraf, H; Schultis, K; von Schwerin, W, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's4 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lorber, J2
Gofferje, H1
Landgraf, H1
von Schwerin, W1
Schultis, K1
Trachtman, H1
Futterweit, S1
Hammer, E1
Siegel, TW1
Oates, P1
Allerton, JP1
Strom, JA1
Gazda-Smith, E1
Synhavsky, A1
Lien, YH1
Shapiro, JI1
Chan, L1
Heilig, CW1
Stromski, ME1
Gullans, SR1
Moore, CM1
Sullivan, JB1
Krenzelok, EP1
Lohr, JW1
McReynolds, J1
Grimaldi, T1
Acara, M1
Farley, TA1
Gault, MH1
Brown, RS1

Trials

1 trial available for sorbitol and Hypernatremia

ArticleYear
Isosorbide in treatment of infantile hydrocephalus.
    Archives of disease in childhood, 1975, Volume: 50, Issue:6

    Topics: Adolescent; Body Weight; Cerebrospinal Fluid Shunts; Clinical Trials as Topic; Diarrhea; Female; Hum

1975

Other Studies

13 other studies available for sorbitol and Hypernatremia

ArticleYear
[Osmo-oncotherapy in brain edema].
    Infusionstherapie und klinische Ernahrung, 1975, Volume: 2, Issue:5

    Topics: Biological Transport; Blood-Brain Barrier; Brain Edema; Fructose; Glucose; Glycerol; Humans; Hyperna

1975
The role of polyols in cerebral cell volume regulation in hypernatremic and hyponatremic states.
    Life sciences, 1991, Volume: 49, Issue:9

    Topics: Aldehyde Reductase; Analysis of Variance; Animals; Brain; Electrolytes; Hypernatremia; Hyponatremia;

1991
Hypernatremia due to repeated doses of charcoal-sorbitol.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:5

    Topics: Adult; Cathartics; Charcoal; Female; Humans; Hypernatremia; Phenobarbital; Poisoning; Sorbitol; Susp

1991
Hypernatremia following treatment of theophylline toxicity with activated charcoal and sorbitol.
    Archives of internal medicine, 1990, Volume: 150, Issue:3

    Topics: Charcoal; Humans; Hypernatremia; Male; Middle Aged; Sorbitol; Theophylline

1990
Effects of hypernatremia on organic brain osmoles.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:5

    Topics: Acute Disease; Amino Acids; Animals; Body Water; Brain; Chronic Disease; Hypernatremia; Inositol; Ma

1990
Methylamine and polyol responses to salt loading in renal inner medulla.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 2

    Topics: Animals; Betaine; Hypernatremia; Inositol; Kidney Medulla; Male; Methylamines; Rats; Rats, Inbred St

1989
Hypernatremia after the use of an activated charcoal-sorbitol suspension.
    The Journal of pediatrics, 1988, Volume: 112, Issue:2

    Topics: Charcoal; Child; Child, Preschool; Humans; Hypernatremia; Infant; Sorbitol; Suspensions

1988
Repetitive doses of the activated charcoal-sorbitol combination: a word of caution.
    The American journal of emergency medicine, 1988, Volume: 6, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Charcoal; Humans; Hypernatremia; Hypokalemia; Sorbitol

1988
Effect of acute and chronic hypernatremia on myoinositol and sorbitol concentration in rat brain and kidney.
    Life sciences, 1988, Volume: 43, Issue:3

    Topics: Acute Disease; Animals; Body Water; Brain; Chronic Disease; Hypernatremia; Inositol; Kidney; Male; O

1988
Severe hypernatremic dehydration after use of an activated charcoal-sorbitol suspension.
    The Journal of pediatrics, 1986, Volume: 109, Issue:4

    Topics: Charcoal; Dehydration; Humans; Hypernatremia; Infant; Male; Sorbitol; Theophylline

1986
Isosorbide in the medical treatment of infantile hydrocephalus.
    Journal of neurosurgery, 1973, Volume: 39, Issue:6

    Topics: Administration, Oral; Cerebral Hemorrhage; Cerebral Ventriculography; Cerebrospinal Fluid Shunts; De

1973
Peritoneal dialysis solutions.
    Canadian Medical Association journal, 1973, Feb-03, Volume: 108, Issue:3

    Topics: Acetates; Acute Kidney Injury; Blood Urea Nitrogen; Calcium; Chlorides; Coma; Glucose; Humans; Hyper

1973
Hypernatremia in hyperosmotic coma?
    Annals of internal medicine, 1971, Volume: 74, Issue:4

    Topics: Coma; Humans; Hypernatremia; Hypertonic Solutions; Male; Osmolar Concentration; Peritoneal Dialysis;

1971