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sorbitol and Hyperkalemia

sorbitol has been researched along with Hyperkalemia in 24 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To describe a case of extensive intestinal necrosis with oral intake of calcium polystyrene sulfonate without sorbitol."7.77Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol. ( Bordes, J; Goutorbe, P; Lacroix, G; Meaudre, E; Montcriol, A; Souraud, JB, 2011)
"Intestinal ischemia is a recognized risk of SPS in sorbitol."7.75Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol. ( Chu, G; McGowan, CE; Moss, SF; Resnick, MB; Saha, S, 2009)
"Colonic necrosis is an unusual complication after treatment of hyperkalemia with sodium polystyrene sulfonate (SPS, Kayexalate) in sorbitol."7.70Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol. ( Barbul, A; Dardik, A; Efron, G; Harrison, MG; Moesinger, RC, 2000)
"Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients."7.69Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997)
"Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency."7.69Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997)
" All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis."7.67Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987)
"A rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake."3.81Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate. ( Chiang, WC; Kao, CC; Kao, TW; Mao, TL; Tsai, YC, 2015)
"To describe a case of extensive intestinal necrosis with oral intake of calcium polystyrene sulfonate without sorbitol."3.77Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol. ( Bordes, J; Goutorbe, P; Lacroix, G; Meaudre, E; Montcriol, A; Souraud, JB, 2011)
" In 2009, the FDA recommended that sorbitol, a cathartic often given with SPS to prevent obstipation, not be added to SPS powder because of associated colonic necrosis."3.76Damned if you do, damned if you don't: potassium binding resins in hyperkalemia. ( Abbott, KC; Watson, M; Yuan, CM, 2010)
"Intestinal ischemia is a recognized risk of SPS in sorbitol."3.75Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol. ( Chu, G; McGowan, CE; Moss, SF; Resnick, MB; Saha, S, 2009)
"Kayexalate (sodium polystyrene sulfonate) in sorbitol has been demonstrated to cause colonic necrosis in a subset of uremic patients who are administered the cation exchange resin for treatment of hyperkalemia."3.71Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings. ( Abraham, SC; Bhagavan, BS; Lee, LA; Rashid, A; Wu, TT, 2001)
"Colonic necrosis is an unusual complication after treatment of hyperkalemia with sodium polystyrene sulfonate (SPS, Kayexalate) in sorbitol."3.70Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol. ( Barbul, A; Dardik, A; Efron, G; Harrison, MG; Moesinger, RC, 2000)
"Sodium polystyrene sulfonate (Kayexalate) in sorbitol given as an enema or orally to treat hyperkalemia has been reported to induce intestinal necrosis in uremic patients."3.69Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. ( Hamilton, SR; Rashid, A, 1997)
"Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency."3.69Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. ( Gardiner, GW, 1997)
" All patients were uremic and received sodium polystyrene (Kayexalate) in sorbitol enemas for the treatment of hyperkalemia shortly before the development of signs and symptoms of colonic necrosis."3.67Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. ( Burdick, JF; Hamilton, SR; Lillemoe, KD; Pennington, LR; Romolo, JL; Williams, GM, 1987)
"Hyperkalemia is a common condition encountered in medical and surgical patients."1.35Ileocolic perforation secondary to sodium polystyrene sulfonate in sorbitol use: a case report. ( Drolet, S; Morcos, MW; Trottier, V, 2009)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's4 (16.67)18.2507
2000's5 (20.83)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oliveira, AA1
Pedro, F1
Craveiro, N1
Cruz, AV1
Almeida, RS1
Luís, PP1
Santos, C1
Kao, CC1
Tsai, YC1
Chiang, WC1
Mao, TL1
Kao, TW1
Castillo-Cejas, MD1
de-Torres-Ramírez, I1
Alonso-Cotoner, C1
Usta, Y1
Ramirez, C1
Dennert, B1
McGowan, CE1
Saha, S1
Chu, G1
Resnick, MB1
Moss, SF1
Trottier, V1
Drolet, S1
Morcos, MW1
Sterns, RH1
Rojas, M1
Bernstein, P1
Chennupati, S1
Watson, M1
Abbott, KC1
Yuan, CM1
Goutorbe, P1
Montcriol, A1
Lacroix, G1
Bordes, J1
Meaudre, E1
Souraud, JB1
QUE, GS1
van der HEM, G1
van der SLIKKE, L1
Weber, DO1
Yarnoz, MD1
Bennett, LN1
Myers, TF1
Lambert, GH1
Rashid, A2
Hamilton, SR2
Gardiner, GW1
Dardik, A1
Moesinger, RC1
Efron, G1
Barbul, A1
Harrison, MG1
Abraham, SC1
Bhagavan, BS1
Lee, LA1
Wu, TT1
Rogers, FB1
Li, SC1
Saltzman, MJ1
Beyer, MM1
Friedman, EA1
Gerstman, BB1
Platt, R1
Wootton, FT1
Rhodes, DF1
Lee, WM1
Fitts, CT1
Lillemoe, KD1
Romolo, JL1
Pennington, LR1
Burdick, JF1
Williams, GM1
Fiedler, H1
Ireland, GW1
Cass, AS1
Ritz, E1
Fanz, HE1
Herzfeld, G1

Reviews

2 reviews available for sorbitol and Hyperkalemia

ArticleYear
Cecal perforation associated with sodium polystyrene sulfonate-sorbitol enemas in a 650 gram infant with hyperkalemia.
    American journal of perinatology, 1996, Volume: 13, Issue:3

    Topics: Cation Exchange Resins; Cecum; Enema; Female; Humans; Hyperkalemia; Infant, Newborn; Infant, Prematu

1996
Acute colonic necrosis associated with sodium polystyrene sulfonate (Kayexalate) enemas in a critically ill patient: case report and review of the literature.
    The Journal of trauma, 2001, Volume: 51, Issue:2

    Topics: Colon; Colonic Diseases; Critical Care; Enema; Humans; Hyperkalemia; Male; Middle Aged; Necrosis; Po

2001

Other Studies

22 other studies available for sorbitol and Hyperkalemia

ArticleYear
Rectal ulcer due to Kayexalate deposition - an unusual case.
    Revista da Associacao Medica Brasileira (1992), 2018, Volume: 64, Issue:8

    Topics: Acute Kidney Injury; Aged, 80 and over; Biopsy; Cation Exchange Resins; Colonoscopy; Female; Humans;

2018
Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2015, Volume: 114, Issue:10

    Topics: Colon; Fatal Outcome; Female; Humans; Hyperkalemia; Ileum; Intestinal Perforation; Kidney Failure, C

2015
Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.
    Revista espanola de enfermedades digestivas, 2013, Volume: 105, Issue:4

    Topics: Cation Exchange Resins; Colon; Humans; Hyperkalemia; Necrosis; Sorbitol

2013
Image of the Month: Emphysematous Gastritis and Necrosis as a Result of Orally Ingested Sodium Polystyrene Sulfonate (Kayexalate) in Sorbitol.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:3

    Topics: Acute Kidney Injury; Aged; Cathartics; Chelating Agents; Gastritis; Gastroscopy; Humans; Hyperkalemi

2016
Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol.
    Southern medical journal, 2009, Volume: 102, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cathartics; Cation Exchange Resins; Cohort Studies; Female; Humans;

2009
Ileocolic perforation secondary to sodium polystyrene sulfonate in sorbitol use: a case report.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009, Volume: 23, Issue:10

    Topics: Cathartics; Cation Exchange Resins; Colonic Diseases; Female; Humans; Hyperkalemia; Ileal Diseases;

2009
Ion-exchange resins for the treatment of hyperkalemia: are they safe and effective?
    Journal of the American Society of Nephrology : JASN, 2010, Volume: 21, Issue:5

    Topics: Animals; Cathartics; Drug Interactions; Humans; Hyperkalemia; Ion Exchange Resins; Polystyrenes; Sor

2010
Damned if you do, damned if you don't: potassium binding resins in hyperkalemia.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:10

    Topics: Animals; Cathartics; Cation Exchange Resins; Colon; Drug Combinations; Drug Synergism; Evidence-Base

2010
Intestinal Necrosis Associated with Orally Administered Calcium Polystyrene Sulfonate Without Sorbitol.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:2

    Topics: Aged; Cecum; Colonic Pseudo-Obstruction; Fatal Outcome; Female; Humans; Hyperkalemia; Intestinal Muc

2011
[The treatment of hyperkalemia with a cation-exchange resin and sorbitol].
    Nederlands tijdschrift voor geneeskunde, 1962, Dec-08, Volume: 106

    Topics: Cations; Humans; Hyperkalemia; Ion Exchange Resins; Sorbitol

1962
Hyperkalemia complicating cardiopulmonary bypass: analysis of risk factors.
    The Annals of thoracic surgery, 1982, Volume: 34, Issue:4

    Topics: Adult; Aged; Aspartic Acid; Blood Glucose; Cardiopulmonary Bypass; Diabetes Complications; Drug Comb

1982
Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition.
    The American journal of surgical pathology, 1997, Volume: 21, Issue:1

    Topics: Adult; Aged; Cation Exchange Resins; Child, Preschool; Cholestyramine Resin; Crystallization; Digest

1997
Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1997, Volume: 11, Issue:7

    Topics: Aged; Cation Exchange Resins; Colon; Diuretics, Osmotic; Drug Therapy, Combination; Fatal Outcome; F

1997
Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol.
    Southern medical journal, 2000, Volume: 93, Issue:5

    Topics: Abdomen, Acute; Administration, Oral; Administration, Rectal; Cathartics; Cation Exchange Resins; Co

2000
Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings.
    The American journal of surgical pathology, 2001, Volume: 25, Issue:5

    Topics: Aged; Aged, 80 and over; Cation Exchange Resins; Crystallization; Duodenum; Endoscopy, Gastrointesti

2001
Mechanism of life prolongation in nephrectomized rats treated with oxidized starch and charcoal.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Animals; Blood Urea Nitrogen; Charcoal; Hyperkalemia; Male; Nephrectomy; Polystyrenes; Potassium; Ra

1976
Use of sodium polystyrene sulfonate in sorbitol in the United States, 1985-1989.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:5

    Topics: Cation Exchange Resins; Drug Utilization; Humans; Hyperkalemia; Polystyrenes; Sorbitol; United State

1991
Colonic necrosis with Kayexalate-sorbitol enemas after renal transplantation.
    Annals of internal medicine, 1989, Dec-01, Volume: 111, Issue:11

    Topics: Cation Exchange Resins; Colon; Enema; Humans; Hyperkalemia; Ion Exchange Resins; Kidney Transplantat

1989
Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis.
    Surgery, 1987, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Animals; Colon; Enema; Female; Humans; Hyperkalemia; Male; Middle Aged; Necrosis;

1987
[Studies on the toxicity of copper disodium ethylenediamine tetra-acetate].
    Archiv fur Toxikologie, 1969, Volume: 25, Issue:2

    Topics: Alanine Transaminase; Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Calcium; Copper

1969
The recognition and management of acute high output renal failure.
    The Journal of urology, 1972, Volume: 108, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Blood Urea Nitrogen; Creatinine; Female; Glucose; Humans; Hyperkal

1972
[Experience with ion exhcange resins in the calcium phase during the management of hyperkalemia].
    Deutsche medizinische Wochenschrift (1946), 1969, Volume: 94, Issue:2

    Topics: Anuria; Calcium; Humans; Hyperkalemia; Ion Exchange Resins; Potassium; Renal Dialysis; Sorbitol

1969