sorbitol has been researched along with Glycosuria in 23 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Glycosuria: The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Utilisation of glucose and sorbitol in medically induced hypercorticalic states was investigated by means of the steroid-glucose-tolerance-test (SGTT) in 9 children, aged 6-16 years suffering from obesity and prediabetes." | 3.66 | [Varying utilization of glucose and sorbitol in drug-induced hypercortical metabolism]. ( Heine, W; Krüger, G; Said, M, 1982) |
| "There were no serious adverse events, adverse events leading to discontinuation, or episodes of hypoglycemia." | 2.79 | Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy Japanese males: a randomized, single-blind, placebo-controlled trial. ( Fukatsu, A; Sakai, S; Samukawa, Y; Sasaki, T; Seino, Y, 2014) |
| " Duration and onset of the pharmacologic effects seemed to be closely correlated with the pharmacokinetic properties of each SGLT2 inhibitor, particularly with respect to high distribution and long retention in the target organ, the kidney." | 1.43 | Characterization and comparison of sodium-glucose cotransporter 2 inhibitors in pharmacokinetics, pharmacodynamics, and pharmacologic effects. ( Imamura, M; Kurosaki, E; Tahara, A; Takasu, T; Yokono, M, 2016) |
| " Single oral dosing studies were performed in rats, mice and dogs to assess the abilities of TS-071 to increase urinary glucose excretion and to lower plasma glucose levels." | 1.37 | TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity. ( Arai, M; Asami, J; Fukuhara, N; Gunji, E; Kitano, K; Kojima, N; Kozakai, A; Okumura-Kitajima, L; Takahashi, K; Takahashi, T; Tomoike, H; Toyoda, H; Uchida, S; Yamamoto, K, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (56.52) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sasaki, T | 1 |
| Seino, Y | 1 |
| Fukatsu, A | 1 |
| Sakai, S | 2 |
| Samukawa, Y | 2 |
| Chino, Y | 1 |
| Nakai, Y | 1 |
| Yamaguchi, J | 1 |
| Nakanishi, T | 1 |
| Tamai, I | 1 |
| Tahara, A | 1 |
| Takasu, T | 1 |
| Yokono, M | 1 |
| Imamura, M | 1 |
| Kurosaki, E | 1 |
| Yamamoto, K | 1 |
| Uchida, S | 1 |
| Kitano, K | 1 |
| Fukuhara, N | 1 |
| Okumura-Kitajima, L | 1 |
| Gunji, E | 1 |
| Kozakai, A | 1 |
| Tomoike, H | 1 |
| Kojima, N | 1 |
| Asami, J | 1 |
| Toyoda, H | 1 |
| Arai, M | 1 |
| Takahashi, T | 1 |
| Takahashi, K | 1 |
| ALPTEKIN, N | 1 |
| SEEBERG, VP | 1 |
| WHITNEY, B | 1 |
| GOLDMAN, D | 1 |
| Heine, W | 1 |
| Krüger, G | 1 |
| Said, M | 1 |
| Siegel, EG | 1 |
| Trapp, VE | 1 |
| Wollheim, CB | 1 |
| Renold, AE | 1 |
| Schmidt, FH | 1 |
| Yoshii, H | 1 |
| Uchino, H | 1 |
| Ohmura, C | 1 |
| Watanabe, K | 1 |
| Tanaka, Y | 1 |
| Kawamori, R | 1 |
| Lenner, RA | 1 |
| Soummer-Dauphant, AM | 1 |
| Chambon, P | 1 |
| Chabert, JM | 1 |
| Schmolke, M | 1 |
| Schleicher, E | 1 |
| Guder, WG | 1 |
| Bates, CJ | 1 |
| Cowen, TD | 1 |
| Evans, PH | 1 |
| McCaleb, ML | 1 |
| Sredy, J | 1 |
| Kiyozumi, M | 2 |
| Inoue, T | 1 |
| Kojima, S | 2 |
| Hidaka, S | 1 |
| Tsuruoka, M | 1 |
| Ono, H | 1 |
| Furukawa, A | 1 |
| Keller, U | 1 |
| Froesch, ER | 1 |
| Gabbay, KH | 1 |
| O'Sullivan, JB | 1 |
| Förster, H | 1 |
| Hoffmann, H | 1 |
| Hoos, I | 1 |
| Worth, HG | 1 |
| Bye, PA | 1 |
| Geser, CA | 1 |
| Horning, EC | 1 |
| Horning, MG | 1 |
2 trials available for sorbitol and Glycosuria
| Article | Year |
|---|---|
Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy Japanese males: a randomized, single-blind, placebo-controlled trial.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administrati | 2014 |
SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria.
Topics: Adult; Animals; Biological Transport; Biomarkers; Dose-Response Relationship, Drug; Female; Glucose; | 2014 |
21 other studies available for sorbitol and Glycosuria
| Article | Year |
|---|---|
Characterization and comparison of sodium-glucose cotransporter 2 inhibitors in pharmacokinetics, pharmacodynamics, and pharmacologic effects.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Delayed-Action Preparations; Diabetes M | 2016 |
TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity.
Topics: Animals; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Deoxyglucose; Diabetes Mellitus; Diabetes | 2011 |
[Effects of sorbitol on blood sugar and glycosuria in diabetes].
Topics: Blood Glucose; Diabetes Mellitus; Glycosuria; Humans; Sorbitol | 1953 |
Blood sugar levels and urinary excretion of intravenously-infused glucose, fructose, galactose, and sorbitol.
Topics: Blood Glucose; Carbohydrates; Fructose; Galactose; Glucose; Glycosuria; Humans; Infusions, Intraveno | 1954 |
[Varying utilization of glucose and sorbitol in drug-induced hypercortical metabolism].
Topics: Adolescent; Adrenocortical Hyperfunction; Child; Glucose; Glucose Tolerance Test; Glycosuria; Humans | 1982 |
Beneficial effects of low-carbohydrate--high-protein diets in long-term diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diet, Diabetic; Dietary Carboh | 1980 |
Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass-spectrometry in type 2 diabetes to assess polyol pathway activity.
Topics: Adult; Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retino | 2001 |
Specially designed sweeteners and food for diabetics--a real need?
Topics: Aged; Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Dietary Carbohydrates; Evaluation Studies as | 1976 |
Conversion of sorbitol to mannitol when used parenterally.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Craniocerebral Trauma; Fructose; Glycosuria; Humans | 1976 |
Renal sorbitol, myo-inositol and glycerophosphorylcholine in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Blood Proteins; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Di | 1992 |
Effect of vitamin C on sorbitol in the lens of guinea-pigs made diabetic with streptozotocin.
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Ascorbic Acid; Ascorbic Acid Deficiency; Blood Gluco | 1992 |
Metabolic abnormalities of the hyperglycemic obese Zucker rat.
Topics: Animals; Fructose; Glucose; Glycosuria; Hyperglycemia; Inositol; Male; Obesity; Rats; Rats, Zucker; | 1992 |
Protection against cis-diamminedichloroplatinum-induced nephrotoxicity in rats by N-benzyl-D-glucamine dithiocarbamate.
Topics: Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Body Weight; Carcinoma 256, Walker; Cispl | 1991 |
Effect of N-benzyl-D-glucamine dithiocarbamate on renal toxicity induced by cadmium-metallothionein in rats.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Bile; Cadmium; Chelating Agents; Glycosuria; Kidn | 1990 |
Metabolism and oxidation of U- 14 C-glucose, xylitol, fructose and sorbitol in the fasted and in the streptozotocin-diabetic rat.
Topics: Amino Sugars; Animals; Anti-Bacterial Agents; Carbon Dioxide; Carbon Isotopes; Diabetes Mellitus; Fa | 1971 |
The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord.
Topics: Animals; Axons; Blood Glucose; Cauda Equina; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dia | 1968 |
[Metabolic effects of various carbohydrates and their significance for infusion therapy].
Topics: Alanine Transaminase; Animals; Bilirubin; Blood Glucose; Body Weight; Carbohydrate Metabolism; Fruct | 1973 |
The effect of sugars on automated urinary oestrogens estimations in pregnancy.
Topics: Autoanalysis; Borohydrides; Estrogens; Evaluation Studies as Topic; Female; Galactose; Glycosuria; H | 1973 |
The utilization and metabolism of intravenous sorbitol.
Topics: Blood Glucose; Fructose; Glycosuria; Humans; Parenteral Nutrition; Potassium; Sodium; Sorbitol; Thro | 1969 |
[Clinical use of xylitol].
Topics: Acidosis; Diabetes Mellitus; Fructose; Glucose; Glycosuria; Humans; Liver Cirrhosis; Parenteral Nutr | 1971 |
Urinary sugars and sugar alcohols.
Topics: Alcohols; Carbohydrates; Chromatography, Gas; Chromatography, Ion Exchange; Glycosuria; Humans; Infa | 1970 |