sorbitol has been researched along with Diabetic Glomerulosclerosis in 54 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the role played by sorbitol accumulation in the kidney in the development of diabetic albuminuria." | 7.72 | Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency. ( Ii, S; Itakura, M; Kudo, E; Moritani, M; Ohta, M; Tachikawa, T; Yamaoka, T; Yoshimoto, K, 2004) |
| "A series of in vivo and in vitro investigations was performed to examine the localisation of sorbitol pathway activity in the rat renal cortex and to investigate the possible relation that the acculumation of sorbitol pathway intermediates in renal cortical tissue may have to the pathogenesis of renal complications in diabetes mellitus." | 7.65 | The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus. ( Hollows, FC; Hutton, JC; Schofield, PJ; Williams, JF, 1975) |
| " Development of a simple, sensitive and rapid method for sorbitol detection is of considerable significance to efficient monitoring of diabetes-associated disorders like cataract, neuropathy, and nephropathy at initial stages." | 5.05 | Bioengineered Polymer/Composites as Advanced Biological Detection of Sorbitol: An Application in Healthcare Sector. ( Batra, K; Minakshi, P; Rani, R; Singh, G, 2020) |
| "Sodium-glucose co-transporter type 2 inhibitors (luseogliflozin 5 mg/day or canagliflozin 100 mg/day) reduced body weight, HbA1c, albuminuria, estimated glomerular filtration rate and office blood pressure." | 3.85 | Sodium-glucose co-transporter type 2 inhibitors reduce evening home blood pressure in type 2 diabetes with nephropathy. ( Kishimoto, M; Ohta, M; Suzuki, H; Takenaka, T; Tomonaga, O, 2017) |
| " Serum-advanced glycation end-products level, malonaldehyde level, sorbitol concentration of red blood cell, 24 h albuminuria excretion were significantly decreased, whereas activity of serum superoxide dismutase and glutathione peroxidase and creatinine clearance rate were increased by mangiferin." | 3.76 | Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats. ( Cui, X; Li, W; Li, X; Sun, X; Zhu, Q, 2010) |
| "We investigated the role played by sorbitol accumulation in the kidney in the development of diabetic albuminuria." | 3.72 | Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency. ( Ii, S; Itakura, M; Kudo, E; Moritani, M; Ohta, M; Tachikawa, T; Yamaoka, T; Yoshimoto, K, 2004) |
| "The relationship between red blood cell sorbitol content and diabetic complications (cataract, retinopathy, neuropathy, and nephropathy) was examined in 23 non-insulin-dependent diabetic (NIDD) patients." | 3.68 | Studies on clinical markers of diabetes mellitus. 6. Red blood cell sorbitol and diabetic complications. ( Aro, T; Fuda, H; Hatano, M; Hiyoshi, S; Katsu, K; Maruyama, S; Sugiura, M; Taguchi, H, 1990) |
| "A series of in vivo and in vitro investigations was performed to examine the localisation of sorbitol pathway activity in the rat renal cortex and to investigate the possible relation that the acculumation of sorbitol pathway intermediates in renal cortical tissue may have to the pathogenesis of renal complications in diabetes mellitus." | 3.65 | The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus. ( Hollows, FC; Hutton, JC; Schofield, PJ; Williams, JF, 1975) |
| "Epalrestat is an inhibitor of aldose reductase in the polyol pathway and is used for the management of diabetic neuropathy clinically." | 1.51 | The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation. ( Aa, JY; Ding, F; Gao, HX; He, J; Sun, RB; Wang, GJ; Wang, JK; Xie, Y; Yang, N; Zeng, CH; Zhang, JW; Zhu, XD, 2019) |
| "In magnolol-treated GK rats, fasting blood glucose and plasma insulin were significantly decreased, and the pancreatic islets also showed strong insulin antigen positivity." | 1.34 | Effects of magnolol (5,5'-diallyl-2,2'-dihydroxybiphenyl) on diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats. ( Jang, DS; Jung, DH; Kim, CS; Kim, JS; Kim, YS; Lee, YM; Sohn, EJ, 2007) |
| "To elucidate diabetic nephropathy involving also renal tubular damage, we measured urinary sorbitol concentration concomitantly with urinary N-acetyl-D-glucosaminidase (NAG) excretion in WBN-kob diabetic rats." | 1.32 | Alteration of urinary sorbitol excretion in WBN-kob diabetic rats - treatment with an aldose reductase inhibitor. ( Hayakawa, N; Itoh, M; Nagasaka, A; Nagata, M; Nakano, I; Oda, N; Sawai, Y; Shinohara, R; Suzuki, A; Takeda, F; Tsugawa, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (31.48) | 18.7374 |
| 1990's | 16 (29.63) | 18.2507 |
| 2000's | 11 (20.37) | 29.6817 |
| 2010's | 8 (14.81) | 24.3611 |
| 2020's | 2 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bessho, R | 1 |
| Takiyama, Y | 1 |
| Takiyama, T | 1 |
| Kitsunai, H | 1 |
| Takeda, Y | 1 |
| Sakagami, H | 1 |
| Ota, T | 1 |
| Rani, R | 1 |
| Singh, G | 1 |
| Batra, K | 1 |
| Minakshi, P | 1 |
| Nakagawa, T | 2 |
| Johnson, RJ | 1 |
| Andres-Hernando, A | 1 |
| Roncal-Jimenez, C | 1 |
| Sanchez-Lozada, LG | 1 |
| Tolan, DR | 1 |
| Lanaspa, MA | 1 |
| Takenaka, T | 1 |
| Kishimoto, M | 1 |
| Ohta, M | 2 |
| Tomonaga, O | 1 |
| Suzuki, H | 1 |
| He, J | 1 |
| Gao, HX | 1 |
| Yang, N | 1 |
| Zhu, XD | 1 |
| Sun, RB | 1 |
| Xie, Y | 1 |
| Zeng, CH | 1 |
| Zhang, JW | 1 |
| Wang, JK | 1 |
| Ding, F | 1 |
| Aa, JY | 1 |
| Wang, GJ | 1 |
| Kojima, N | 1 |
| Williams, JM | 1 |
| Takahashi, T | 1 |
| Miyata, N | 1 |
| Roman, RJ | 1 |
| Zanoli, L | 1 |
| Granata, A | 1 |
| Lentini, P | 1 |
| Rastelli, S | 1 |
| Fatuzzo, P | 1 |
| Rapisarda, F | 1 |
| Castellino, P | 1 |
| ElGamal, H | 1 |
| Munusamy, S | 1 |
| Forbes, JM | 1 |
| Coughlan, MT | 1 |
| Cooper, ME | 3 |
| Li, X | 3 |
| Hu, J | 1 |
| Zhang, R | 1 |
| Sun, X | 2 |
| Zhang, Q | 1 |
| Guan, X | 1 |
| Chen, J | 1 |
| Zhu, Q | 2 |
| Li, S | 1 |
| Chao, CY | 1 |
| Mong, MC | 1 |
| Chan, KC | 1 |
| Yin, MC | 1 |
| Cui, X | 1 |
| Li, W | 1 |
| Hotta, N | 1 |
| Fujita, T | 2 |
| Ouchi, H | 1 |
| Isogai, S | 2 |
| Amano, S | 1 |
| Yamagishi, Si | 1 |
| Kato, N | 1 |
| Inagaki, Y | 1 |
| Okamoto, T | 1 |
| Makino, M | 2 |
| Taniko, K | 1 |
| Hirooka, H | 1 |
| Jomori, T | 1 |
| Takeuchi, M | 1 |
| Ii, S | 1 |
| Kudo, E | 1 |
| Yamaoka, T | 2 |
| Tachikawa, T | 1 |
| Moritani, M | 1 |
| Itakura, M | 2 |
| Yoshimoto, K | 1 |
| Tsugawa, T | 1 |
| Shinohara, R | 2 |
| Nagasaka, A | 2 |
| Nakano, I | 1 |
| Takeda, F | 1 |
| Nagata, M | 2 |
| Oda, N | 1 |
| Sawai, Y | 1 |
| Hayakawa, N | 2 |
| Suzuki, A | 1 |
| Itoh, M | 2 |
| Yokozawa, T | 1 |
| Yamabe, N | 1 |
| Cho, EJ | 1 |
| Oowada, S | 1 |
| Sohn, EJ | 1 |
| Kim, CS | 1 |
| Kim, YS | 1 |
| Jung, DH | 1 |
| Jang, DS | 1 |
| Lee, YM | 1 |
| Kim, JS | 1 |
| Koya, D | 1 |
| Brownlee, M | 1 |
| Cerami, A | 1 |
| Ward, JD | 1 |
| Nishimura, C | 1 |
| Yamashita, K | 1 |
| Yamada, T | 1 |
| Fujimoto, J | 1 |
| Kokai, Y | 1 |
| Soulis-Liparota, T | 1 |
| Dunlop, M | 1 |
| Jerums, G | 1 |
| Faiman, G | 1 |
| Ganguly, P | 1 |
| Mehta, A | 1 |
| Thliveris, JA | 1 |
| Love, A | 1 |
| Cotter, MA | 1 |
| Cameron, NE | 1 |
| Inokuchi, T | 1 |
| Ohe, K | 1 |
| Hayashi, R | 1 |
| Kakizawa, H | 1 |
| Uchimura, K | 1 |
| Hamada, M | 1 |
| Aono, T | 1 |
| Morrisey, K | 1 |
| Steadman, R | 1 |
| Williams, JD | 1 |
| Phillips, AO | 1 |
| Tsukushi, S | 1 |
| Katsuzaki, T | 1 |
| Aoyama, I | 1 |
| Takayama, F | 1 |
| Miyazaki, T | 1 |
| Shimokata, K | 1 |
| Niwa, T | 1 |
| Tomlinson, DR | 1 |
| Gilbert, RE | 1 |
| Hutton, JC | 1 |
| Schofield, PJ | 1 |
| Williams, JF | 1 |
| Hollows, FC | 1 |
| Daumerie-Goffinet, C | 1 |
| Lambert, AE | 1 |
| Spiro, RG | 1 |
| Servo, C | 1 |
| Pitkänen, E | 1 |
| Larkins, RG | 1 |
| Dunlop, ME | 1 |
| Kawazu, S | 1 |
| Tomono, S | 1 |
| Lohr, JW | 1 |
| Bennett, MI | 1 |
| Pochal, MA | 1 |
| McReynolds, J | 1 |
| Acara, M | 1 |
| Willsky, GR | 1 |
| Iwamoto, Y | 1 |
| Kumari, K | 1 |
| Murthy, PS | 1 |
| Sahib, MK | 1 |
| Hatano, M | 1 |
| Katsu, K | 1 |
| Fuda, H | 1 |
| Taguchi, H | 1 |
| Aro, T | 1 |
| Hiyoshi, S | 1 |
| Sugiura, M | 1 |
| Maruyama, S | 1 |
| Mauer, SM | 1 |
| Steffes, MW | 1 |
| Azar, S | 1 |
| Brown, DM | 1 |
| Sakamoto, N | 1 |
| Engerman, RL | 1 |
| Kern, TS | 1 |
| Greene, D | 1 |
| Cohen, M | 1 |
| Kilo, C | 1 |
| Kador, PF | 1 |
| Kinoshita, JH | 1 |
| Sharpless, NE | 1 |
| Sharkey, TP | 1 |
| Osawa, G | 1 |
| Kinoshita, Y | 1 |
| Ito, G | 1 |
| Dawidowicz, A | 1 |
| Raja, RM | 1 |
| Moros, JG | 1 |
| Kramer, MS | 1 |
| Rosenbaum, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 DiabetesL a Open-label Trial[NCT02502071] | Phase 4 | 45 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Urine uric acid crystals were identified by polarized microscopy (Polarized light imaging Zeiss Axiovert 135; 0.3NA objective), and pictures were captured from each urine sample. UA crystals were defined dichotomously as being present or absent. (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
| Intervention | participants (Number) | |
|---|---|---|
| Day 1 (pre-therapy) | Day 2 (post-therapy) | |
| Sodium Bicarbonate | 14 | 3 |
Urine uric acid were evaluated using a QuantiChrom UA kit assay (DIUA-250) with quantitative colorimetric UA determination at 590 nm (BioAssay System, California, USA). (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
| Intervention | mg/dl (Geometric Mean) | |
|---|---|---|
| Day 1 (pre-therapy) | Day 2 (post-therapy) | |
| Sodium Bicarbonate | 23.81 | 22.30 |
20 reviews available for sorbitol and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Bioengineered Polymer/Composites as Advanced Biological Detection of Sorbitol: An Application in Healthcare Sector.
Topics: Biosensing Techniques; Cataract; Diabetic Nephropathies; Diabetic Neuropathies; Electrochemical Tech | 2020 |
Fructose Production and Metabolism in the Kidney.
Topics: Animals; Cardiomegaly; Diabetic Nephropathies; Dietary Sugars; Energy Metabolism; Fatty Acids; Fruct | 2020 |
Sodium-glucose linked transporter-2 inhibitors in chronic kidney disease.
Topics: Animals; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rat | 2015 |
Aldose Reductase as a Drug Target for Treatment of Diabetic Nephropathy: Promises and Challenges.
Topics: Aldehyde Reductase; Catalytic Domain; Diabetic Nephropathies; Enzyme Inhibitors; Glucose; Glycation | 2017 |
Oxidative stress as a major culprit in kidney disease in diabetes.
Topics: Animals; Cytosol; Diabetic Nephropathies; Disease Models, Animal; Energy Metabolism; Glucose; Glucos | 2008 |
[Risk factors for diabetic complications: Abnormality of polyol metabolism].
Topics: Aldehyde Reductase; Animals; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; F | 2002 |
[Expression mechanisms and incident factors of diabetic nephropathy].
Topics: Animals; Cytokines; Diabetic Nephropathies; Fructose; Genetic Predisposition to Disease; Glomerular | 2002 |
[Diabetic nephropathy--predictive methods].
Topics: Albuminuria; Animals; Biomarkers; Collagen Type IV; Diabetic Nephropathies; Fibronectins; Fructose; | 2002 |
[Molecular understanding of adverse effects of hyperglycemia in diabetic nephropathy].
Topics: Animals; Diabetic Nephropathies; Energy Metabolism; Fructose; Glucose; Glycation End Products, Advan | 2007 |
The biochemistry of the complications of diabetes mellitus.
Topics: Animals; Axonal Transport; Basement Membrane; Blood Platelets; Blood Proteins; Cataract; Diabetes Co | 1981 |
Mitogen-activated protein kinases as glucose transducers for diabetic complications.
Topics: Animals; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Glucose; Humans; Mitog | 1999 |
The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Glucose; Humans; Ischemia | 1999 |
[Diabetic microangiopathies].
Topics: Basement Membrane; Blood Viscosity; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies | 1978 |
Search for a biochemical basis of diabetic microangiopathy.
Topics: Animals; Basement Membrane; Carbohydrate Metabolism; Collagen; Diabetic Nephropathies; Glucose; Glyc | 1976 |
The link between hyperglycaemia and diabetic nephropathy.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose; Glyco | 1992 |
Value of glucose control in preventing complications of diabetes.
Topics: Adult; Animals; Blood Glucose; Blood Pressure; Blood Vessels; Body Weight; Collagen; Diabetes Compli | 1985 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; | 1985 |
Diabetes mellitus--present problems and new research. VI. Nephropathy and neuropathy.
Topics: Adult; Alcohol Oxidoreductases; Animals; Cerebrospinal Fluid; Child; Diabetes Mellitus, Type 1; Diab | 1971 |
[Diabetic nephrosis and dialysis treatment].
Topics: Adult; Diabetic Nephropathies; Female; Humans; Insulin; Peritoneal Dialysis; Renal Dialysis; Sorbito | 1972 |
[Diabetic cataract and modern views on the etiology and pathogenesis of vascular complications during diabetes].
Topics: Age Factors; Cataract; Cataract Extraction; Diabetes Complications; Diabetes Mellitus, Type 1; Diabe | 1971 |
34 other studies available for sorbitol and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy.
Topics: Animals; Cell Hypoxia; Diabetes Mellitus; Diabetic Nephropathies; Hypoglycemic Agents; Hypoxia-Induc | 2019 |
Sodium-glucose co-transporter type 2 inhibitors reduce evening home blood pressure in type 2 diabetes with nephropathy.
Topics: Albuminuria; Biomarkers; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canag | 2017 |
The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation.
Topics: Albuminuria; Aldehyde Reductase; Animals; Diabetic Nephropathies; Enzyme Inhibitors; Fructose; Inosi | 2019 |
Effects of a new SGLT2 inhibitor, luseogliflozin, on diabetic nephropathy in T2DN rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabe | 2013 |
Urocortin ameliorates diabetic nephropathy in obese db/db mice.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Cell Line; Connective Tissue Growth Factor | 2008 |
Anti-glycative and anti-inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice.
Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Caffeic Acids; Cyt | 2010 |
Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Cell Proliferation; Cells, Cultured; Collagen Type IV; Creatini | 2010 |
Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes.
Topics: Aldehyde Reductase; Animals; Blood-Retinal Barrier; Capillary Permeability; Cattle; Cells, Cultured; | 2002 |
Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.
Topics: Albuminuria; Aldehyde Reductase; Animals; Diabetic Nephropathies; Humans; L-Iditol 2-Dehydrogenase; | 2004 |
Alteration of urinary sorbitol excretion in WBN-kob diabetic rats - treatment with an aldose reductase inhibitor.
Topics: Acetylglucosaminidase; Aldehyde Reductase; Animals; Diabetic Nephropathies; Kidney; Male; Models, An | 2004 |
A study on the effects to diabetic nephropathy of Hachimi-jio-gan in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Creatinine; Diabetes Mellitus, Experiment | 2004 |
Effects of magnolol (5,5'-diallyl-2,2'-dihydroxybiphenyl) on diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats.
Topics: Animals; Biphenyl Compounds; Blood Glucose; Collagen Type IV; Creatinine; Diabetes Mellitus, Experim | 2007 |
[The problem of the complications of diabetes].
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellit | 1984 |
Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA.
Topics: Aldehyde Reductase; Animals; Base Sequence; Blotting, Southern; Blotting, Western; Diabetic Angiopat | 1995 |
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat.
Topics: Albuminuria; Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydrox | 1995 |
Effect of statil on kidney structure, function and polyol accumulation in diabetes mellitus.
Topics: Aldehyde Reductase; Animals; Diabetic Nephropathies; Kidney; Male; Phthalazines; Rats; Rats, Sprague | 1993 |
Impaired myelinated fiber regeneration following freeze-injury in rats with streptozotocin-induced diabetes: involvement of the polyol pathway.
Topics: Acetanilides; Aldehyde Reductase; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Di | 1995 |
Effect of an aldose reductase inhibitor on glomerular basement membrane anionic sites in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Albuminuria; Aldehyde Reductase; Animals; Anions; Basement Membrane; Blood Glu | 1995 |
Changes in erythrocyte sorbitol concentrations measured using an improved assay system in patients with diabetic complications and treated with aldose reductase inhibitor.
Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabet | 1998 |
Renal proximal tubular cell fibronectin accumulation in response to glucose is polyol pathway dependent.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Diabetic Nephropathies; Enzyme Inhibitors; Fibronect | 1999 |
Increased erythrocyte 3-DG and AGEs in diabetic hemodialysis patients: role of the polyol pathway.
Topics: Adult; Aged; Aldehyde Reductase; Arginine; Creatinine; Deoxyglucose; Diabetic Nephropathies; Enzyme- | 1999 |
The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus.
Topics: Animals; Chromatography, Gas; Diabetes Mellitus; Diabetic Nephropathies; Fructose; Glucose; Inositol | 1975 |
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.
Topics: Aged; Blood Glucose; Creatinine; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Ethers, Cy | 1975 |
[Diabetic microangiopathy--its biochemical bases].
Topics: Animals; Basement Membrane; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Glu | 1991 |
Effect of vanadate on renal hypertrophy and sorbitol accumulation in streptozotocin induced diabetes in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertrophy; Inosit | 1991 |
[Diabetic complication].
Topics: Aldehyde Reductase; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Diabe | 1991 |
Monoaminoguanidine prevents sorbitol accumulation, nonenzymatic protein glycosylation and development of kidney lesions in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycos | 1991 |
Studies on clinical markers of diabetes mellitus. 6. Red blood cell sorbitol and diabetic complications.
Topics: Biomarkers; Cataract; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Eryth | 1990 |
Effects of sorbinil on glomerular structure and function in long-term-diabetic rats.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Blood Glucose; Diabetes Mellitus, Experimental; Diab | 1989 |
[Causes and treatment of diabetic complications].
Topics: Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Glycosylatio | 1989 |
Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dogs; Galactitol; Galactosemias; H | 1989 |
The pathogenesis and prevention of diabetic neuropathy and nephropathy.
Topics: Aldehyde Reductase; Diabetic Nephropathies; Diabetic Neuropathies; Glucose; Humans; Phosphatidylinos | 1988 |
Aldose reductase inhibition, glomerular metabolism, and diabetic nephropathy.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Imidazoles; Im | 1985 |
Hyperosmotic coma complicating peritoneal dialysis with sorbitol dialysate.
Topics: Coma; Diabetic Nephropathies; Humans; Hypertonic Solutions; Male; Middle Aged; Osmolar Concentration | 1970 |