sorbitol has been researched along with Chronic Disease in 33 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the use of sorbitol as an inexpensive alternative to lactulose for treating constipation in the elderly." | 9.06 | Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose. ( Aske, DM; Busch, DL; Lederle, FA; Mattox, KM; West, MJ, 1990) |
| "X-ray investigation of the colon was conducted in 292 patients with clinically diagnosed chronic colitis: standard 3-phase irrigoscopy-in 189 patients and a primary double contrast study of the colon with citrate-sorbitol-barium suspension in 103." | 7.68 | [Primary double contrast study of the large intestine using citrate-sorbitol-barium suspension in the diagnosis of chronic colitis]. ( Sidorov, VS, 1991) |
| "The purpose of this study was to evaluate the use of sorbitol as an inexpensive alternative to lactulose for treating constipation in the elderly." | 5.06 | Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose. ( Aske, DM; Busch, DL; Lederle, FA; Mattox, KM; West, MJ, 1990) |
| "SGL5213 and miglitol improved obesity, liver dysfunction, insulin resistance, and the NAFLD severity." | 4.02 | Protective effect of SGL5213, a potent intestinal sodium-glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice. ( Honda, Y; Imajo, K; Iwaki, M; Kessoku, T; Kobayashi, T; Nagashima, Y; Nakajima, A; Nogami, A; Ogawa, Y; Ozaki, A; Saito, S; Tomeno, W; Yoneda, M, 2021) |
| "X-ray investigation of the colon was conducted in 292 patients with clinically diagnosed chronic colitis: standard 3-phase irrigoscopy-in 189 patients and a primary double contrast study of the colon with citrate-sorbitol-barium suspension in 103." | 3.68 | [Primary double contrast study of the large intestine using citrate-sorbitol-barium suspension in the diagnosis of chronic colitis]. ( Sidorov, VS, 1991) |
| "We performed breath hydrogen analyses in 13 healthy children (9 to 36 months of age) and seven children (14 to 27 months of age) with chronic nonspecific diarrhea after they had ingested pear, grape, and apple juices and a 2% sorbitol solution." | 3.67 | Carbohydrate malabsorption following fruit juice ingestion in young children. ( Etienne, NL; Hyams, JS; Leichtner, AM; Theuer, RC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (39.39) | 18.7374 |
| 1990's | 9 (27.27) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Liauw, S | 1 |
| Saibil, F | 1 |
| Honda, Y | 1 |
| Ozaki, A | 1 |
| Iwaki, M | 1 |
| Kobayashi, T | 1 |
| Nogami, A | 1 |
| Kessoku, T | 1 |
| Ogawa, Y | 1 |
| Tomeno, W | 1 |
| Imajo, K | 1 |
| Yoneda, M | 1 |
| Saito, S | 1 |
| Nagashima, Y | 1 |
| Nakajima, A | 1 |
| Whittaker, A | 1 |
| Currie, AE | 1 |
| Turner, MA | 1 |
| Field, DJ | 1 |
| Mulla, H | 1 |
| Pandya, HC | 1 |
| Frank, D | 1 |
| Montskó, G | 1 |
| Juricskay, I | 1 |
| Borsiczky, B | 1 |
| Cseh, G | 1 |
| Kocsis, B | 1 |
| Nagy, T | 1 |
| Nagy, ÁK | 1 |
| Kovács, GL | 1 |
| Miseta, A | 1 |
| Funatsu, H | 1 |
| Yamashita, H | 1 |
| Suzuki, Y | 1 |
| Kumeda, Y | 1 |
| Inaba, M | 1 |
| Nishizawa, Y | 1 |
| Van Zandt, MC | 1 |
| Sibley, EO | 1 |
| McCann, EE | 1 |
| Combs, KJ | 1 |
| Flam, B | 1 |
| Sawicki, DR | 1 |
| Sabetta, A | 1 |
| Carrington, A | 1 |
| Sredy, J | 1 |
| Howard, E | 1 |
| Mitschler, A | 1 |
| Podjarny, AD | 1 |
| Callender, ST | 1 |
| Hyams, JS | 2 |
| Thurston, JH | 1 |
| McDougal, DB | 1 |
| Hauhart, RE | 1 |
| Schulz, DW | 1 |
| Fox, GN | 1 |
| Kneepkens, CM | 1 |
| Hoekstra, JH | 1 |
| Duncan, B | 1 |
| Barton, LL | 1 |
| Eicher, ML | 1 |
| Chmielarczyk, VT | 1 |
| Erdman, SH | 1 |
| Hulett, RL | 1 |
| Gupta, R | 1 |
| Gupta, S | 1 |
| Joshi, K | 1 |
| Ganguly, NK | 1 |
| Ott, P | 1 |
| Clemmesen, O | 1 |
| Keiding, S | 1 |
| Bitoun, M | 1 |
| Tappaz, M | 1 |
| Winkler, G | 1 |
| Kempler, P | 1 |
| Conn, HO | 2 |
| Leevy, CM | 1 |
| Vlahcevic, ZR | 1 |
| Rodgers, JB | 2 |
| Maddrey, WC | 1 |
| Seeff, L | 1 |
| Levy, LL | 1 |
| Sterzel, RB | 1 |
| Stegaru, B | 1 |
| Dietmann, K | 1 |
| Schaumann, HJ | 1 |
| Schwab, I | 1 |
| Dini, L | 1 |
| Amici, F | 1 |
| Aguzzi, P | 1 |
| Lifshitz, F | 1 |
| Ament, ME | 1 |
| Kleinman, RE | 1 |
| Klish, W | 1 |
| Lebenthal, E | 1 |
| Perman, J | 1 |
| Udall, JN | 1 |
| Sidorov, VS | 1 |
| Lederle, FA | 1 |
| Busch, DL | 1 |
| Mattox, KM | 1 |
| West, MJ | 1 |
| Aske, DM | 1 |
| Lien, YH | 1 |
| Shapiro, JI | 1 |
| Chan, L | 1 |
| Etienne, NL | 1 |
| Leichtner, AM | 1 |
| Theuer, RC | 1 |
| Lohr, JW | 1 |
| McReynolds, J | 1 |
| Grimaldi, T | 1 |
| Acara, M | 1 |
| Sheleketina, II | 1 |
| Halaburt, H | 1 |
| Lester, J | 1 |
| Bucko, A | 1 |
| Kiley, JE | 1 |
| Balint, JA | 1 |
| Elkington, SG | 1 |
| Floch, MH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safe Excipient Exposure in Neonates and Small ChildreN - a Retrospective, Descriptive Study Off the Amount of Ethanol, Propylene Glycol, Benzyl Alcohol, Parabens, Acesulfam k, Aspartame, Glycerol, Sorbitol and Polysorbate-80 Exposed to Pediatric Patients[NCT02545712] | 630 participants (Actual) | Observational | 2016-01-31 | Active, not recruiting | |||
| Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children[NCT02016703] | 185 participants (Actual) | Interventional | 2006-03-31 | Completed | |||
| Effect of Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Liver Cirrhosis; a Randomized Clinical Trial (PEGHE Trial)[NCT04436601] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-03-09 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for sorbitol and Chronic Disease
| Article | Year |
|---|---|
[Molecular biology in development and progression of diabetic retinopathy].
Topics: Animals; Capillary Permeability; Chronic Disease; Cytokines; Diabetic Retinopathy; Disease Progressi | 2002 |
[Early detection of diabetic neuropathy].
Topics: Aldehyde Reductase; Chronic Disease; Diabetic Neuropathies; Evidence-Based Medicine; Glycation End P | 2002 |
[Diabetes mellitus and osteoporosis].
Topics: Animals; Bone and Bones; Chronic Disease; Diabetes Complications; Diagnosis, Differential; Humans; H | 2002 |
Treatment of iron deficiency.
Topics: Acute Disease; Administration, Oral; Anemia, Hypochromic; Child; Child, Preschool; Chronic Disease; | 1982 |
[The pathogenesis of diabetic and hepatic neuropathies].
Topics: Chronic Disease; Diabetic Neuropathies; Glucose; Hemodynamics; Hemorheology; Humans; Lipid Peroxidat | 2001 |
Role of juice carbohydrate malabsorption in chronic nonspecific diarrhea in children.
Topics: Beverages; Child, Preschool; Chronic Disease; Diarrhea; Diarrhea, Infantile; Dietary Carbohydrates; | 1992 |
4 trials available for sorbitol and Chronic Disease
| Article | Year |
|---|---|
Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial.
Topics: Aged; Ammonia; Blood; Chronic Disease; Clinical Trials as Topic; Disaccharides; Electroencephalograp | 1977 |
Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose.
Topics: Aged; Aged, 80 and over; Chronic Disease; Constipation; Cost-Benefit Analysis; Double-Blind Method; | 1990 |
Comparison of results of long-term treatment of chronic hepatic encephalopathy with lactulose and sorbitol.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Disaccharides; Female; Hepatic Encephalopathy; Huma | 1973 |
Lactulose in the treatment of chronic portal-systemic encephalopathy. A double-blind clinical trial.
Topics: Adult; Aged; Alcoholism; Ammonia; Brain Diseases; Chronic Disease; Clinical Trials as Topic; Colon; | 1969 |
23 other studies available for sorbitol and Chronic Disease
| Article | Year |
|---|---|
Sorbitol: Often forgotten cause of osmotic diarrhea.
Topics: Chewing Gum; Chronic Disease; Diarrhea; Female; Humans; Middle Aged; Osmolar Concentration; Sorbitol | 2019 |
Protective effect of SGL5213, a potent intestinal sodium-glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice.
Topics: 1-Deoxynojirimycin; Animals; Chronic Disease; Diet, High-Fat; Dietary Sucrose; Disease Models, Anima | 2021 |
Toxic additives in medication for preterm infants.
Topics: Administration, Oral; Chronic Disease; Dexamethasone; Drug Administration Schedule; Excipients; Fema | 2009 |
Clindamycin release determined by high performance liquid chromatography from a novel low-cost local drug delivery system: a new potential treatment option for chronic osteomyelitis.
Topics: Anti-Bacterial Agents; Capsules; Chromatography, High Pressure Liquid; Chronic Disease; Clindamycin; | 2011 |
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications.
Topics: Acetic Acid; Aldehyde Reductase; Animals; Chronic Disease; Diabetes Mellitus, Experimental; Drug Des | 2004 |
Chronic abdominal pain caused by sorbitol malabsorption.
Topics: Abdomen; Child, Preschool; Chronic Disease; Female; Humans; Malabsorption Syndromes; Pain; Sorbitol | 1982 |
Effects of acute, subacute, and chronic diabetes on carbohydrate and energy metabolism in rat sciatic nerve. Relation to mechanisms of peripheral neuropathy.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Chronic Disease; Diabetes M | 1995 |
Treatment and cost concerns for chronic constipation.
Topics: Cathartics; Child; Chronic Disease; Constipation; Cost Control; Drug Costs; Humans; Lactulose; Sorbi | 1994 |
Fruit juice and chronic nonspecific diarrhea.
Topics: Breath Tests; Child; Child, Preschool; Chronic Disease; Diarrhea; Fructose; Fruit; Humans; Hydrogen; | 1993 |
Medication-induced pneumatosis intestinalis.
Topics: Cerebral Palsy; Child; Chronic Disease; Diarrhea; Enteral Nutrition; Humans; Male; Pneumatosis Cysto | 1997 |
Role of iron and iron chelation therapy in oxygen free radical mediated tissue injury in an ascending mouse model of chronic pyelonephritis.
Topics: Animals; Chelation Therapy; Chronic Disease; Citric Acid; Deferoxamine; Disease Models, Animal; Drug | 1997 |
Interpretation of simultaneous measurements of hepatic extraction fractions of indocyanine green and sorbitol: evidence of hepatic shunts and capillarization?
Topics: Acute Disease; Adult; Aged; Capillaries; Chronic Disease; Female; Humans; Indocyanine Green; Liver; | 2000 |
Gene expression of taurine transporter and taurine biosynthetic enzymes in brain of rats with acute or chronic hyperosmotic plasma. A comparative study with gene expression of myo-inositol transporter, betaine transporter and sorbitol biosynthetic enzyme.
Topics: Acute Disease; Aldehyde Reductase; Animals; Brain; Carboxy-Lyases; Carrier Proteins; Chronic Disease | 2000 |
[Treatment of reversible, uremia-inducing factors in chronic interstitial nephritis].
Topics: Blood Volume; Central Venous Pressure; Chronic Disease; Furosemide; Humans; Kidney; Nephritis, Inter | 1975 |
[Hemodynamic and metabolic changes in patients with bronchial asthma during therapy with isosorbide and dinitrate retard].
Topics: Asthma; Chronic Disease; Hemodynamics; Humans; Isosorbide; Nitrates; Sorbitol | 1975 |
[Very slow cholangiography in hyperbilirubinemia and chronic diseases of the liver].
Topics: Cholangiography; Chronic Disease; Contrast Media; Humans; Hyperbilirubinemia; Liver Diseases; Sorbit | 1975 |
[Primary double contrast study of the large intestine using citrate-sorbitol-barium suspension in the diagnosis of chronic colitis].
Topics: Adult; Barium Sulfate; Chronic Disease; Citrates; Citric Acid; Colitis; Colon; Contrast Media; Diagn | 1991 |
Effects of hypernatremia on organic brain osmoles.
Topics: Acute Disease; Amino Acids; Animals; Body Water; Brain; Chronic Disease; Hypernatremia; Inositol; Ma | 1990 |
Carbohydrate malabsorption following fruit juice ingestion in young children.
Topics: Breath Tests; Carbohydrate Metabolism; Carbohydrates; Child, Preschool; Chronic Disease; Diarrhea; F | 1988 |
Effect of acute and chronic hypernatremia on myoinositol and sorbitol concentration in rat brain and kidney.
Topics: Acute Disease; Animals; Body Water; Brain; Chronic Disease; Hypernatremia; Inositol; Kidney; Male; O | 1988 |
[Effect of sorbitol preparations on the vitamin saturation of the organism in patients with chronic hepatocholecystitis].
Topics: Adult; Aged; Ascorbic Acid; Avitaminosis; Cholecystitis; Chronic Disease; Citrates; Female; Hepatiti | 1969 |
Leptomeningeal changes following lumbar myelography with water-soluble contrast media (meglumine iothalamate and methiodal sodium).
Topics: Adipates; Adult; Aged; Arachnoiditis; Back Pain; Chronic Disease; Female; Glucosamine; Humans; Iotha | 1973 |
[Diet therapy in pancreatic diseases].
Topics: Acute Disease; Amino Acids; Chronic Disease; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; | 1974 |