Page last updated: 2024-11-06

sorbitol and Brain Diseases

sorbitol has been researched along with Brain Diseases in 18 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
" The hypotensive side effect can be used for treatment of reactive arterial hypertension in neurosurgical patients during surgery where this therapy is advantageous per se because of its cerebral dehydrating effects."1.27[Acute lowering of blood pressure by infusion of hyperosmolal sorbitol solution in brain operations. Dangerous adverse effect or favorable side effect?]. ( Panning, B; Piepenbrock, S; Schäffer, J; Stolke, D, 1988)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199012 (66.67)18.7374
1990's5 (27.78)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guiberson, NGL1
Pineda, A1
Abramov, D1
Kharel, P1
Carnazza, KE1
Wragg, RT1
Dittman, JS1
Burré, J1
Papadakis, N1
Mark, VH1
Nau, HE1
Conn, HO2
Mangar, D1
O'Connor, TM1
Bergmann, M1
Silling-Engelhardt, G1
Schnabel, R1
Gulotta, F1
Fritz, W1
Schmidt, K1
Panning, B3
Stolke, D2
Higer, HP1
Just, M1
Grigat, M1
Meindl, S1
Jungke, M1
Bielke, G1
Pedrosa, P1
Kunze, S1
Voth, D1
Piepenbrock, S2
Frýdl, V1
Schäffer, J1
Bircher, J2
Müller, J1
Guggenheim, P1
Haemmerli, UP2
Cambier, J1
Mason, M1
Dairou, R1
Elkington, SG1
Floch, MH1
Williams, R1
Brown, H1
Trey, C1
McDermott, WV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy[NCT04937062]Early Phase 150 participants (Anticipated)Interventional2021-03-01Enrolling by invitation
Effect of Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Liver Cirrhosis; a Randomized Clinical Trial (PEGHE Trial)[NCT04436601]Phase 4102 participants (Anticipated)Interventional2020-03-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sorbitol and Brain Diseases

ArticleYear
[Critical comments on reports of fatalities in hereditary fructose intolerance in adulthood from the viewpoint of neuroanesthesia].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1988, Volume: 23, Issue:4

    Topics: Adult; Brain Diseases; Fructose; Fructose Intolerance; Fructose Metabolism, Inborn Errors; Humans; I

1988

Trials

4 trials available for sorbitol and Brain Diseases

ArticleYear
Blindness induced by double-blindedness.
    Archives of internal medicine, 1981, Volume: 141, Issue:7

    Topics: Brain Diseases; Clinical Trials as Topic; Humans; Portasystemic Shunt, Surgical; Sorbitol

1981
Lactulose in the treatment of chronic portal-systemic encephalopathy. A double-blind clinical trial.
    The New England journal of medicine, 1969, Aug-21, Volume: 281, Issue:8

    Topics: Adult; Aged; Alcoholism; Ammonia; Brain Diseases; Chronic Disease; Clinical Trials as Topic; Colon;

1969
Lactulose in the treatment of portal-systemic encephalopathy. Report of a symposium.
    Gastroenterology, 1970, Volume: 58, Issue:4

    Topics: Adult; Animals; Brain Diseases; Child; Dogs; Electroencephalography; Fructose; Hepatic Encephalopath

1970
Lactulose treatment of hepatic encephalopathy in outpatients.
    Archives of surgery (Chicago, Ill. : 1960), 1971, Volume: 102, Issue:1

    Topics: Adolescent; Aged; Alcoholism; Ambulatory Care; Ammonia; Brain Diseases; Colon; Diet Therapy; Dietary

1971

Other Studies

13 other studies available for sorbitol and Brain Diseases

ArticleYear
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
    Nature communications, 2018, 09-28, Volume: 9, Issue:1

    Topics: Animals; Brain Diseases; Caenorhabditis elegans Proteins; Cell Line, Tumor; Cells, Cultured; HEK293

2018
Intermittent decortication and progressive hyperthermia, hypertension and tachycardia following methylglucamine iothalamate ventriculogram.
    Applied neurophysiology, 1980, Volume: 43, Issue:1-2

    Topics: Adult; Brain Diseases; Cerebral Decortication; Cerebral Ventriculography; Fever; Humans; Hypertensio

1980
Electroencephalography (EEG) after introduction of water soluble contrast media into cerebrospinal fluid (CSF).
    Acta neurochirurgica, 1981, Volume: 57, Issue:1-2

    Topics: Adolescent; Adult; Aged; Brain Diseases; Cerebral Ventriculography; Child; Convulsants; Electroencep

1981
Hyponatremic encephalopathy after endometrial ablation.
    JAMA, 1994, Feb-02, Volume: 271, Issue:5

    Topics: Brain Diseases; Dextrans; Endometrium; Female; Glycine; Humans; Hyponatremia; Postoperative Complica

1994
Hyponatremic encephalopathy after endometrial ablation.
    JAMA, 1994, Feb-02, Volume: 271, Issue:5

    Topics: Brain Diseases; Endometrium; Ethanol; Female; Humans; Hyponatremia; Postoperative Complications; Sor

1994
[Therapy-induced cerebro-renal oxalosis?].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1991, Volume: 46, Issue:4

    Topics: Aged; Brain Diseases; Calcium Oxalate; Cerebral Arteries; Critical Care; Crystallization; Endotheliu

1991
[Transcranial Doppler ultrasound monitoring of osmo-oncotherapy in neurosurgical patients with brain edema].
    Neurochirurgia, 1990, Volume: 33, Issue:6

    Topics: Blood Flow Velocity; Brain Diseases; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Criti

1990
[Cerebral perfusion pressure in acute blood pressure decrease with hyperosmolar sorbitol in anesthesia conditions].
    Neurochirurgia, 1990, Volume: 33, Issue:2

    Topics: Anesthesia, General; Blood Pressure; Brain Diseases; Brain Neoplasms; Cerebrovascular Circulation; H

1990
[Gadolinium dimeglumine gadopentetate compared to CPMG sequencing and image synthesis].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1988, Volume: 148, Issue:3

    Topics: Brain Diseases; Brain Neoplasms; Contrast Media; Drug Combinations; Gadolinium; Gadolinium DTPA; Hum

1988
[Cerebrorenal oxalate formation--a metabolic abnormality following parenteral infusions of carbohydrate exchange substances].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1987, Volume: 133, Issue:4

    Topics: Alcohol Withdrawal Delirium; Brain Diseases; Calcium Oxalate; Fructose; Humans; Kidney Calculi; Male

1987
[Acute lowering of blood pressure by infusion of hyperosmolal sorbitol solution in brain operations. Dangerous adverse effect or favorable side effect?].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1988, Volume: 23, Issue:2

    Topics: Blood Pressure; Brain Diseases; Female; Hemodynamics; Humans; Hypertonic Solutions; Intracranial Pre

1988
Treatment of chronic portal-systemic encephalopathy with lactulose.
    Lancet (London, England), 1966, Apr-23, Volume: 1, Issue:7443

    Topics: Brain Diseases; Diet Therapy; Dietary Proteins; Disaccharides; Humans; Liver Cirrhosis; Male; Middle

1966
[Letter: Myoclonic encephalopathy and bismuth salt poisoning].
    La Nouvelle presse medicale, 1974, Dec-21, Volume: 3, Issue:44

    Topics: Bismuth; Brain Diseases; Drug Synergism; Electroencephalography; Humans; Male; Mental Disorders; Mid

1974