sorbitol has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 148 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Development of a simple, sensitive and rapid method for sorbitol detection is of considerable significance to efficient monitoring of diabetes-associated disorders like cataract, neuropathy, and nephropathy at initial stages." | 5.05 | Bioengineered Polymer/Composites as Advanced Biological Detection of Sorbitol: An Application in Healthcare Sector. ( Batra, K; Minakshi, P; Rani, R; Singh, G, 2020) |
| "An orally active inhibitor of aldose reductase, 1,3-dioxo-1H-benz[de]-isoquinoline-2(3H)acetic acid (AY-22,284), prevented cataractous changes in cultured lenses exposed to high concentrations of galactose." | 3.65 | Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor. ( Dvornik, E; Gabbay, KH; Kinoshita, JH; Krami, M; Merola, LO; Sestanj, K; Simard-Duquesne, N; Varma, SD, 1973) |
| "Diabetic retinopathy is similarly related to sorbitol accumulation and may be prevented or reversed by inhibition of aldose reductase." | 2.37 | NIH conference. Aldose reductase and complications of diabetes. ( Cobo, LM; Cogan, DG; Datilis, MB; Kador, PF; Kinoshita, JH; Kupfer, C; Robison, G, 1984) |
| "Mononeuritis (or mononeuritis multiplex) seems to be the result of ischaemia due to intrinsic or extrinsic (altered coagulability) vascular disease." | 2.37 | [Pathogenesis of diabetic neuropathies]. ( Arlot, S; Lalau, JD; Quichaud, J, 1985) |
| "Fidarestat treatment did not affect diabetes-induced increase in glucose concentrations, but normalized sorbitol and fructose concentrations (enzymatic spectrofluorometric assays) as well as 12(S)-hydroxyeicosatetraenoic concentration (ELISA), a measure of 12/15-lipoxygenase activity, in the sciatic nerve and spinal cord." | 1.38 | Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy. ( Hirooka, H; Nadler, JL; Obrosova, IG; Shevalye, H; Stavniichuk, R, 2012) |
| "At 8 months galactosemia reduced NCV to 58% of control values, while ARI-treatment for 8 months improved NCV to 71% of control values." | 1.29 | Galactosemia produces ARI-preventable nodal changes similar to those of diabetic neuropathy. ( Basso, M; Cherian, PV; Hohman, TC; Kamijo, M; Sima, AA, 1994) |
| "Iloprost was administered intraperitoneally to streptozotocin-induced diabetic rats at a dose of 10 micrograms/kg/day for a month." | 1.28 | Effect of a prostaglandin I2 derivative (iloprost) on peripheral neuropathy of diabetic rats. ( Ito, H; Kanazawa, A; Miwa, T; Ohno, A; Tanaka, A, 1992) |
| "Myo-inositol was reduced approximately 50%." | 1.28 | [Alterations in the sorbitol pathway and Na(+)-K(+)-ATPase activity of peripheral nerve of alloxan-induced diabetic rats]. ( Lu, KM; Zhong, XL; Zhu, QY; Zhu, XX, 1990) |
| "Myo-inositol treatment did not affect nerve levels." | 1.28 | The effect of aldose reductase inhibition on the pattern of nerve conduction deficits in diabetic rats. ( Cameron, NE; Cotter, MA; Robertson, S, 1989) |
| "Treatment with Sorbinil (25 mg/kg/day, p." | 1.27 | Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil. ( Mayer, JH; Moriarty, RJ; Tomlinson, DR, 1984) |
| "Sorbinil treatment for 4 wk reduced sciatic nerve sorbitol concentration and improved motor nerve conduction velocity in diabetes of 2-9 mo duration." | 1.26 | The effect of aldose reductase inhibition on motor nerve conduction velocity in diabetic rats. ( Hanwell, MA; Satchell, PM; Turtle, JR; Yue, DK, 1982) |
| "Myoinositol concentration was significantly decreased in patients with polyneuropathy compared with the controls." | 1.26 | Cerebrospinal fluid sorbitol and myoinositol in diabetic polyneuropathy. ( Bergström, L; Fogelholm, R; Servo, C, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (47.30) | 18.7374 |
| 1990's | 54 (36.49) | 18.2507 |
| 2000's | 18 (12.16) | 29.6817 |
| 2010's | 4 (2.70) | 24.3611 |
| 2020's | 2 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Rani, R | 1 |
| Singh, G | 1 |
| Batra, K | 1 |
| Minakshi, P | 1 |
| Srivastava, B | 1 |
| Sen, S | 1 |
| Sen, K | 1 |
| Li, G | 1 |
| Sun, C | 1 |
| Wang, Y | 1 |
| Liu, Y | 1 |
| Gang, X | 1 |
| Gao, Y | 1 |
| Li, F | 2 |
| Xiao, X | 1 |
| Wang, G | 1 |
| Hao, W | 1 |
| Tashiro, S | 1 |
| Hasegawa, T | 1 |
| Sato, Y | 1 |
| Kobayashi, T | 1 |
| Tando, T | 1 |
| Katsuyama, E | 1 |
| Fujie, A | 1 |
| Watanabe, R | 1 |
| Morita, M | 1 |
| Miyamoto, K | 1 |
| Morioka, H | 1 |
| Nakamura, M | 1 |
| Matsumoto, M | 1 |
| Amizuka, N | 1 |
| Toyama, Y | 1 |
| Miyamoto, T | 1 |
| Freeman, OJ | 1 |
| Unwin, RD | 1 |
| Dowsey, AW | 1 |
| Begley, P | 1 |
| Ali, S | 1 |
| Hollywood, KA | 1 |
| Rustogi, N | 1 |
| Petersen, RS | 1 |
| Dunn, WB | 1 |
| Cooper, GJ | 1 |
| Gardiner, NJ | 1 |
| Matsumoto, T | 1 |
| Ono, Y | 2 |
| Kurono, M | 2 |
| Kuromiya, A | 1 |
| Nakamura, K | 1 |
| Bril, V | 4 |
| Sim, HJ | 1 |
| Jeong, JS | 1 |
| Kwon, HJ | 1 |
| Kang, TH | 1 |
| Park, HM | 1 |
| Lee, YM | 1 |
| Kim, SY | 1 |
| Hong, SP | 1 |
| Stavniichuk, R | 1 |
| Shevalye, H | 1 |
| Hirooka, H | 1 |
| Nadler, JL | 1 |
| Obrosova, IG | 2 |
| Oates, PJ | 2 |
| Hotta, N | 9 |
| Hamada, Y | 6 |
| Suzuki, Y | 1 |
| Buchanan, RA | 1 |
| Szabó, C | 1 |
| Pacher, P | 1 |
| Southan, GJ | 1 |
| Abatan, OI | 1 |
| Charniauskaya, T | 1 |
| Stevens, MJ | 4 |
| Yagihashi, S | 4 |
| Romanovsky, D | 1 |
| Cruz, NF | 1 |
| Dienel, GA | 1 |
| Dobretsov, M | 1 |
| Perkins, BA | 1 |
| Brownlee, M | 1 |
| Cerami, A | 1 |
| Mayer, JH | 4 |
| Tomlinson, DR | 11 |
| Moriarty, RJ | 1 |
| Cogan, DG | 1 |
| Kinoshita, JH | 3 |
| Kador, PF | 2 |
| Robison, G | 1 |
| Datilis, MB | 1 |
| Cobo, LM | 1 |
| Kupfer, C | 1 |
| Clarke, BF | 2 |
| Young, RJ | 2 |
| Martyn, CN | 2 |
| Ewing, DJ | 2 |
| Kikkawa, R | 4 |
| Hatanaka, I | 4 |
| Yasuda, H | 5 |
| Kobayashi, N | 2 |
| Shigeta, Y | 5 |
| Terashima, H | 3 |
| Morimura, T | 2 |
| Tsuboshima, M | 1 |
| Jacobson, M | 1 |
| Sharma, YR | 1 |
| Cotlier, E | 1 |
| Hollander, JD | 1 |
| Finegold, D | 1 |
| Lattimer, SA | 10 |
| Nolle, S | 1 |
| Bernstein, M | 1 |
| Greene, DA | 15 |
| Gabbay, KH | 6 |
| Ward, JD | 2 |
| Low, PA | 3 |
| Tuck, RR | 1 |
| Dyck, PJ | 3 |
| Schmelzer, JD | 3 |
| Yao, JK | 4 |
| Fagius, J | 1 |
| Jameson, S | 1 |
| Yue, DK | 1 |
| Hanwell, MA | 1 |
| Satchell, PM | 1 |
| Turtle, JR | 1 |
| Winegrad, AI | 1 |
| Simmons, DA | 1 |
| Martin, DB | 1 |
| Sherman, WR | 3 |
| Hallcher, LM | 1 |
| Service, FJ | 1 |
| O'Brien, PC | 1 |
| Grina, LA | 1 |
| Palumbo, PJ | 1 |
| Swanson, CJ | 1 |
| Koh, N | 6 |
| Sakakibara, F | 5 |
| Nakamura, J | 4 |
| Wakao, T | 3 |
| Hara, T | 3 |
| Mori, K | 3 |
| Naruse, K | 3 |
| Nakashima, W | 1 |
| Kakuta, H | 3 |
| Fukasawa, H | 3 |
| Wright, RA | 1 |
| Nukada, H | 1 |
| Kamijo, M | 5 |
| Basso, M | 1 |
| Cherian, PV | 1 |
| Hohman, TC | 2 |
| Sima, AA | 11 |
| Thurston, JH | 1 |
| McDougal, DB | 1 |
| Hauhart, RE | 1 |
| Schulz, DW | 1 |
| Tilton, RG | 2 |
| Chang, K | 1 |
| Nyengaard, JR | 1 |
| Van den Enden, M | 1 |
| Ido, Y | 3 |
| Williamson, JR | 3 |
| McHowat, J | 1 |
| Chang, KC | 1 |
| Arrigoni-Martelli, E | 1 |
| Orfalian, Z | 1 |
| Kilo, C | 2 |
| Corr, PB | 1 |
| Suzuki, E | 1 |
| Yasuda, K | 2 |
| Miyazaki, S | 1 |
| Takeda, N | 1 |
| Inouye, H | 1 |
| Omawari, N | 1 |
| Miura, K | 1 |
| Matsui, T | 1 |
| Nakamura, Y | 1 |
| Ishikawa, H | 1 |
| Matsuura, A | 3 |
| Kobayashi, F | 1 |
| Frank, RN | 1 |
| Carrington, AL | 1 |
| Diemel, LT | 1 |
| Ettlinger, CB | 1 |
| Smith, WJ | 1 |
| Fernyhough, P | 1 |
| Van Huysen, C | 1 |
| Wada, R | 1 |
| Nagai, K | 1 |
| Cameron, NE | 4 |
| Cotter, MA | 4 |
| Maxfield, EK | 1 |
| Inukai, S | 1 |
| Agata, M | 1 |
| Sato, M | 1 |
| Naitou, A | 1 |
| Matsukawa, H | 1 |
| Goto, M | 1 |
| Hirano, F | 1 |
| Tanaka, H | 1 |
| Okamoto, K | 1 |
| Makino, Y | 1 |
| Inaba, M | 1 |
| Nomura, Y | 1 |
| Fukawa, E | 1 |
| Miura, T | 1 |
| Tani, T | 1 |
| Makino, I | 1 |
| Shindo, H | 3 |
| Thomas, TP | 1 |
| Larkin, DD | 1 |
| Karihaloo, AK | 1 |
| Inada, H | 1 |
| Onaya, T | 3 |
| Ristic, H | 1 |
| Merry, A | 1 |
| Nakashima, E | 2 |
| Ashizawa, N | 2 |
| Yoshida, M | 2 |
| Sugiyama, Y | 2 |
| Akaike, N | 2 |
| Ohbayashi, S | 2 |
| Aotsuka, T | 2 |
| Abe, N | 1 |
| Fukushima, K | 1 |
| Ito, T | 1 |
| Nishimura, C | 1 |
| Takahashi, Y | 1 |
| Saito, T | 1 |
| Omori, Y | 1 |
| Hounsom, L | 1 |
| Akira, T | 1 |
| Naka, H | 1 |
| Hayashi, R | 1 |
| Hayakawa, N | 1 |
| Makino, M | 2 |
| Nagata, M | 1 |
| Kakizawa, H | 1 |
| Uchimura, K | 1 |
| Hamada, M | 1 |
| Aono, T | 1 |
| Fujita, T | 1 |
| Shinohara, R | 1 |
| Nagasaka, A | 1 |
| Itoh, M | 1 |
| Pierzchala, K | 1 |
| Kishi, Y | 1 |
| Zollman, PJ | 1 |
| Nickander, KK | 1 |
| Tritschler, HJ | 1 |
| Kato, K | 3 |
| Nakayama, M | 1 |
| Chaya, S | 1 |
| Kasuya, Y | 1 |
| Mizubayashi, R | 1 |
| Miwa, K | 1 |
| Yasuda, Y | 1 |
| Kamiya, H | 1 |
| Ienaga, K | 1 |
| Sundkvist, G | 1 |
| Dahlin, LB | 2 |
| Nilsson, H | 1 |
| Eriksson, KF | 1 |
| Lindgärde, F | 1 |
| Rosén, I | 1 |
| Sullivan, K | 1 |
| Kato, N | 2 |
| Mizuno, K | 2 |
| Suzuki, T | 1 |
| Yoshii, H | 1 |
| Uchino, H | 1 |
| Ohmura, C | 1 |
| Watanabe, K | 1 |
| Tanaka, Y | 1 |
| Kawamori, R | 1 |
| Coppey, LJ | 1 |
| Davidson, EP | 1 |
| Dunlap, JA | 1 |
| Lund, DD | 1 |
| Yorek, MA | 1 |
| Winkler, G | 1 |
| Kempler, P | 1 |
| Liang, X | 1 |
| Cui, L | 1 |
| Guo, S | 1 |
| Daumerie-Goffinet, C | 1 |
| Lambert, AE | 1 |
| Balasse, EO | 1 |
| Mehnert, H | 1 |
| Servo, C | 1 |
| Bergström, L | 1 |
| Fogelholm, R | 1 |
| Ohno, A | 1 |
| Kanazawa, A | 1 |
| Tanaka, A | 1 |
| Miwa, T | 1 |
| Ito, H | 1 |
| Sonobe, M | 3 |
| Hisanaga, T | 1 |
| Kawabata, T | 1 |
| Maeda, K | 1 |
| Matsubara, A | 1 |
| Nakano, K | 2 |
| Tawata, M | 2 |
| Aida, K | 2 |
| Komori, H | 1 |
| Sakamoto, N | 3 |
| Nathaniel, V | 2 |
| Das, AK | 1 |
| Vijayaraghavan, MV | 1 |
| Kito, S | 1 |
| Yamamura, Y | 1 |
| Wasada, T | 1 |
| Ao, S | 1 |
| Shingu, Y | 1 |
| Kikuchi, C | 1 |
| Takano, Y | 1 |
| Nomura, K | 1 |
| Fujiwara, T | 1 |
| Ohkubo, Y | 1 |
| Notsu, Y | 1 |
| Yamaguchi, I | 1 |
| Nishikawa, M | 1 |
| Yoshida, K | 1 |
| Okamoto, M | 1 |
| Itoh, Y | 1 |
| Kohsaka, M | 1 |
| Nakayama, K | 1 |
| Mizota, M | 1 |
| Miwa, I | 1 |
| Okuda, J | 1 |
| Iwamoto, Y | 1 |
| Mirrlees, DJ | 1 |
| Lu, KM | 1 |
| Zhong, XL | 1 |
| Zhu, XX | 1 |
| Zhu, QY | 1 |
| Suzuki, K | 1 |
| Saito, N | 1 |
| Sakata, Y | 1 |
| Toyota, T | 1 |
| Goto, Y | 1 |
| Willars, GB | 1 |
| Robinson, JP | 2 |
| Archer, DR | 1 |
| McLean, WG | 1 |
| Compton, AM | 1 |
| Keen, P | 1 |
| Schmidt, RE | 1 |
| Plurad, SB | 1 |
| Robertson, S | 1 |
| Yamashita, M | 2 |
| Terada, M | 2 |
| Huitian, Z | 1 |
| Lattimer-Greene, S | 1 |
| Umehara, F | 1 |
| Greene, D | 1 |
| Ward, KK | 1 |
| Yoshida, T | 1 |
| Nishioka, H | 1 |
| Yoshioka, K | 1 |
| Kondo, M | 1 |
| Chandler, CE | 1 |
| Miller, LJ | 1 |
| Pitts, NE | 1 |
| Vreeland, F | 1 |
| Shaw, GL | 1 |
| Peterson, MJ | 1 |
| Mehta, DJ | 1 |
| Collier, J | 1 |
| Gundersen, K | 1 |
| Reid, W | 1 |
| McEwen, TA | 1 |
| Brown, MB | 1 |
| Zimmerman, BR | 1 |
| Vilen, TH | 1 |
| Minnerath, SR | 1 |
| Karnes, JL | 1 |
| Poduslo, JF | 1 |
| Miyamoto, Y | 1 |
| Amenomori, M | 1 |
| Motoyama, Y | 1 |
| Gregersen, G | 1 |
| Lehtinen, JM | 1 |
| Hyvönen, SK | 1 |
| Uusitupa, M | 1 |
| Puhakainen, E | 1 |
| Halonen, T | 1 |
| Kilpeläinen, H | 1 |
| Bertelsmann, FW | 1 |
| Heimans, JJ | 1 |
| van Rooy, JC | 1 |
| Popp-Snijders, C | 1 |
| van der Veen, EA | 1 |
| Inaba, H | 1 |
| Yano, T | 1 |
| Lalau, JD | 1 |
| Arlot, S | 1 |
| Quichaud, J | 1 |
| Kimura, M | 1 |
| Iida, M | 1 |
| Sharpless, NE | 1 |
| Dvornik, E | 1 |
| Simard-Duquesne, N | 1 |
| Krami, M | 1 |
| Sestanj, K | 1 |
| Varma, SD | 1 |
| Merola, LO | 2 |
| Wieland, OH | 1 |
| Sharkey, TP | 1 |
| Lekishvili, VP | 1 |
| O'Sullivan, JB | 1 |
| Ahuja, MM | 1 |
| Draznin, NM | 1 |
| Ide, T | 1 |
| Field, RA | 1 |
| Stewart, MA | 1 |
| Anthony, S | 1 |
42 reviews available for sorbitol and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Bioengineered Polymer/Composites as Advanced Biological Detection of Sorbitol: An Application in Healthcare Sector.
Topics: Biosensing Techniques; Cataract; Diabetic Nephropathies; Diabetic Neuropathies; Electrochemical Tech | 2020 |
Polyol pathway and diabetic peripheral neuropathy.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Enzyme Activation; Enzyme Inhibitors; Humans; L- | 2002 |
[Risk factors for diabetic complications: Abnormality of polyol metabolism].
Topics: Aldehyde Reductase; Animals; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; F | 2002 |
[Risk factors and onset mechanisms of diabetic neuropathy].
Topics: Aldehyde Reductase; Animals; Blood Glucose; Capillary Permeability; Diabetic Neuropathies; Genetic P | 2002 |
[Early detection of diabetic neuropathy].
Topics: Aldehyde Reductase; Chronic Disease; Diabetic Neuropathies; Evidence-Based Medicine; Glycation End P | 2002 |
Sural nerve sorbitol in patients with diabetic sensorimotor polyneuropathy.
Topics: Adult; Aged; Diabetic Neuropathies; Humans; MEDLINE; Middle Aged; Reference Values; Sorbitol; Sural | 2004 |
[Metabolic factors in the pathogenesis of diabetic neuropathies].
Topics: Aldehyde Reductase; Diabetic Neuropathies; Genetic Predisposition to Disease; Glucose; Glycation End | 2005 |
[Early diagnosis of peripheral neuropathy in patients with impaired glucose tolerance (IGT)].
Topics: Diabetic Neuropathies; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hyperglycemia; | 2005 |
Emerging therapies for diabetic neuropathy: a clinical overview.
Topics: Aldehyde Reductase; Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus, Type 2; Dia | 2005 |
Aldose reductase, still a compelling target for diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Controlled Clinical Trials as Topic; Diabetic Neuropathies; Disease Mod | 2008 |
The biochemistry of the complications of diabetes mellitus.
Topics: Animals; Axonal Transport; Basement Membrane; Blood Platelets; Blood Proteins; Cataract; Diabetes Co | 1981 |
Defects of axonal transport in diabetes mellitus--a possible contribution to the aetiology of diabetic neuropathy.
Topics: Animals; Axonal Transport; Body Temperature; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dia | 1984 |
NIH conference. Aldose reductase and complications of diabetes.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Cataract; Corneal Diseases; Diabetic Neuropathies; Di | 1984 |
[The biochemical basis of the complications of diabetes].
Topics: Aldehyde Reductase; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Fruc | 1984 |
The aldose reductase controversy.
Topics: Aldehyde Reductase; Animals; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimen | 1994 |
Limitations of the polyol hypothesis in the pathobiology of experimental diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Spinal; Humans; Models, Ne | 1993 |
Metabolic alterations of peripheral nerve in diabetes.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Disease Models, Animal; Enzyme Inhibitors; Fatty | 1996 |
Does neuropathy develop in animal models?
Topics: Animals; Axotomy; Biological Transport; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dise | 1997 |
[Metabolic disorder of polyol pathway].
Topics: Diabetes Mellitus; Diabetic Neuropathies; Fructose; Glucose; Humans; NAD; NADP; Sorbitol | 1997 |
[SG-210].
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inh | 1997 |
New concepts and insights on pathogenesis and treatment of diabetic complications: polyol pathway and its inhibition.
Topics: Animals; Diabetes Complications; Diabetic Neuropathies; Humans; Sorbitol | 1997 |
[Contemporary views on the pathogenesis of diabetic neuropathy].
Topics: Adenosine Triphosphatases; Basement Membrane; Diabetic Neuropathies; Endothelium, Vascular; Free Rad | 1998 |
Future prevention and treatment of diabetic neuropathy.
Topics: Diabetic Neuropathies; Forecasting; Glycosylation; Humans; Hyperglycemia; Nerve Growth Factors; Oxid | 1998 |
Mitogen-activated protein kinases as glucose transducers for diabetic complications.
Topics: Animals; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Glucose; Humans; Mitog | 1999 |
[The pathogenesis of diabetic and hepatic neuropathies].
Topics: Chronic Disease; Diabetic Neuropathies; Glucose; Hemodynamics; Hemorheology; Humans; Lipid Peroxidat | 2001 |
[Diabetic microangiopathies].
Topics: Basement Membrane; Blood Viscosity; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies | 1978 |
Review: pathogenesis, progression, and therapeutic intervention of diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Axons; Cataract; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Huma | 1992 |
Diabetic peripheral neuropathy.
Topics: Diabetic Neuropathies; Humans; Inositol; Sorbitol | 1991 |
[Diabetic neuropathy--a review of pathological studies].
Topics: Adolescent; Adult; Aged; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mo | 1991 |
Pathogenesis of diabetic neuropathy: role of altered phosphoinositide metabolism.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Humans; Inositol; Neural Conduction; Periphe | 1989 |
Are disturbances of sorbitol, phosphoinositide, and Na+-K+-ATPase regulation involved in pathogenesis of diabetic neuropathy?
Topics: Animals; Diabetic Neuropathies; Glucose; Humans; Inositol; Neural Conduction; Peripheral Nerves; Pho | 1988 |
[Sorbitol, phosphoinositides and Na K-ATPase in the pathogenesis of diabetic complications].
Topics: Aldehyde Reductase; Animals; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Human | 1988 |
Sorbitol, myo-inositol and sodium-potassium ATPase in diabetic peripheral nerve.
Topics: Animals; Blood Glucose; Diabetic Neuropathies; Energy Metabolism; Humans; Inositol; Sodium-Potassium | 1986 |
Altered sorbitol and myo-inositol metabolism as the basis for defective protein kinase C and (Na,K)-ATPase regulation in diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Humans; Inositol; Peripheral Nerves | 1986 |
[Diabetic neuropathy: theories on its metabolic pathogenesis].
Topics: Animals; Diabetic Neuropathies; Humans; Peripheral Nerves; Phosphatidylinositols; Sorbitol | 1987 |
Value of glucose control in preventing complications of diabetes.
Topics: Adult; Animals; Blood Glucose; Blood Pressure; Blood Vessels; Body Weight; Collagen; Diabetes Compli | 1985 |
[Pathogenesis of diabetic neuropathies].
Topics: Animals; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Energy Metabolism; Humans; | 1985 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; | 1985 |
The sorbitol pathway and the complications of diabetes.
Topics: Alcohol Oxidoreductases; Animals; Carbohydrate Metabolism; Cataract; Central Nervous System; Diabete | 1973 |
Diabetes mellitus--present problems and new research. VI. Nephropathy and neuropathy.
Topics: Adult; Alcohol Oxidoreductases; Animals; Cerebrospinal Fluid; Child; Diabetes Mellitus, Type 1; Diab | 1971 |
[New theories of the pathogenesis of diabetic neuropathies].
Topics: Animals; Carbohydrate Metabolism; Demyelinating Diseases; Diabetes Mellitus, Experimental; Diabetic | 1974 |
Diabetic neuropathy.
Topics: Cranial Nerves; Diabetic Neuropathies; Lipid Metabolism; Nerve Tissue; Neural Conduction; Peripheral | 1972 |
8 trials available for sorbitol and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Aldose reductase inhibition in diabetes.
Topics: Aldehyde Reductase; Animals; Clinical Trials as Topic; Diabetes Mellitus, Experimental; Diabetes Mel | 1984 |
Effects of aldose reductase inhibitor treatment in diabetic polyneuropathy - a clinical and neurophysiological study.
Topics: Adult; Albuminuria; Aldehyde Reductase; Autonomic Nervous System; Clinical Trials as Topic; Diabetic | 1981 |
[Clinical study on jinmaitong composita on diabetic peripheral neuropathy].
Topics: Aged; Aldehyde Reductase; Diabetic Neuropathies; Drugs, Chinese Herbal; Erythrocytes; Humans; Male; | 1999 |
Peripheral nerve repair following ARI treatment.
Topics: Aldehyde Reductase; Axons; Diabetic Neuropathies; Double-Blind Method; Humans; Imidazoles; Imidazoli | 1991 |
Clinical experience with sorbinil--an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Autonomic Nervous System Diseases; Blood Glucose; Clinical Trials as To | 1986 |
Six-month treatment with sorbinil in asymptomatic diabetic neuropathy. Failure to improve abnormal nerve function.
Topics: Adult; Aldehyde Reductase; Autonomic Nervous System; Clinical Trials as Topic; Diabetic Neuropathies | 1987 |
Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil.
Topics: Action Potentials; Aldehyde Reductase; Biopsy; Clinical Trials as Topic; Demyelinating Diseases; Dia | 1988 |
The effect of sorbinil treatment on red cell sorbitol levels and clinical and electrophysiological parameters of diabetic neuropathy.
Topics: Adult; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Erythrocytes; Female; H | 1986 |
98 other studies available for sorbitol and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Free serum sorbitol and its interaction with caffeine: A suggestive approach for plausible remediation of diabetic neuropathy.
Topics: Caffeine; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Humans; Sorbitol; Spectr | 2022 |
A clinical and neuropathological study of Chinese patients with diabetic peripheral neuropathy.
Topics: Adult; Biopsy; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Neuro | 2014 |
Hyperglycemia Promotes Schwann Cell De-differentiation and De-myelination via Sorbitol Accumulation and Igf1 Protein Down-regulation.
Topics: Aldehyde Reductase; Animals; Calcitriol; Cell Dedifferentiation; Cells, Cultured; Demyelinating Dise | 2015 |
Metabolic Dysfunction Is Restricted to the Sciatic Nerve in Experimental Diabetic Neuropathy.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; | 2016 |
Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Diabetic Neuropathies; Enzyme Inhibitors; Male; Neur | 2008 |
HPLC with pulsed amperometric detection for sorbitol as a biomarker for diabetic neuropathy.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Diabetic Neuropathies; Humans; Male; Mice | 2009 |
Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy.
Topics: Aldehyde Reductase; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood Gluco | 2012 |
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diureti | 2004 |
Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Anim | 2006 |
Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Blood Glucose; Diabetes Mellitus, Experimental; Diabe | 1983 |
Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Choline O-Acetyltransferase; Diabetes Mellitus, Exper | 1984 |
Effect of a new aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) on peripheral nerve disorders in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Erythrocytes; I | 1983 |
Diabetic complications in lens and nerve and their prevention by sulindac or sorbinil: two novel aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Diabetic Retinopathy; Imidazoles; Imidazolidines | 1983 |
Polyol pathway activity and myo-inositol metabolism. A suggested relationship in the pathogenesis of diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fructose; Gluco | 1983 |
Prevention of peripheral nerve dysfunction by an aldose reductase inhibitor in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Motor Neu | 1984 |
[The problem of the complications of diabetes].
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellit | 1984 |
Prevention of some electrophysiologic and biochemical abnormalities with oxygen supplementation in experimental diabetic neuropathy.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diabetic Neuropath | 1984 |
The effect of aldose reductase inhibition on motor nerve conduction velocity in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Female; Imidazoles; Imidazolidines; Motor Neuron | 1982 |
Has one diabetic complication been explained?
Topics: Animals; Axons; Diabetes Mellitus; Diabetic Neuropathies; Fructose; Humans; Imidazoles; Imidazolidin | 1983 |
Human diabetic endoneurial sorbitol, fructose, and myo-inositol related to sural nerve morphometry.
Topics: Diabetes Mellitus, Type 1; Diabetic Neuropathies; Fructose; Humans; Inositol; Middle Aged; Periphera | 1980 |
Prevention of abnormalities in motor nerve conduction and nerve blood-flow by a prostacyclin analog, beraprost sodium, in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetic Neuro | 1995 |
Effect of a potent new aldose reductase inhibitor, (5-(3-thienyltetrazol-1-yl)acetic acid (TAT), on diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic N | 1995 |
Vascular and metabolic factors in the pathogenesis of experimental diabetic neuropathy in mature rats.
Topics: Animals; Diabetic Neuropathies; Fructose; Glucose; Inositol; Male; Neural Conduction; Peripheral Ner | 1994 |
Galactosemia produces ARI-preventable nodal changes similar to those of diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Axons; Body Weight; Diabetic Neuropathies; Fructose; Galactitol; Galact | 1994 |
Effects of acute, subacute, and chronic diabetes on carbohydrate and energy metabolism in rat sciatic nerve. Relation to mechanisms of peripheral neuropathy.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Chronic Disease; Diabetes M | 1995 |
Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Eye; Fructos | 1995 |
Neural dysfunction and metabolic imbalances in diabetic rats. Prevention by acetyl-L-carnitine.
Topics: Acetylcarnitine; Animals; Ca(2+) Mg(2+)-ATPase; Carnitine; Diabetes Mellitus, Experimental; Diabetic | 1994 |
1H-NMR analysis of nerve edema in the streptozotocin-induced diabetic rat.
Topics: Aldehyde Reductase; Animals; Body Water; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ede | 1994 |
Pharmacological profiles of a novel aldose reductase inhibitor, SPR-210, and its effects on streptozotocin-induced diabetic rats.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Cattle; Diabetes Mellitus, Experimental; Diabetic Neuro | 1994 |
Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic N | 1993 |
Peripheral neuropathy in the WBN/Kob rat with chronic pancreatitis and spontaneous diabetes.
Topics: Action Potentials; Animals; Axons; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; | 1993 |
Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats.
Topics: Action Potentials; Animals; Butylated Hydroxytoluene; Capillaries; Diabetes Mellitus, Experimental; | 1993 |
Characterization of a novel aldose reductase inhibitor, TAT, and its effects on streptozotocin-induced diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Humans; In Vitro Techniques; Male; Mice; Mice, I | 1993 |
Natural course of diabetic peripheral neuropathy in spontaneous-onset diabetic Chinese hamsters.
Topics: Aging; Animals; Cricetinae; Cricetulus; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Electrophy | 1995 |
Modulation of basal nitric oxide-dependent cyclic-GMP production by ambient glucose, myo-inositol, and protein kinase C in SH-SY5Y human neuroblastoma cells.
Topics: Base Sequence; Cholinergic Fibers; Cyclic GMP; Diabetic Neuropathies; Glucose; Humans; Inositol; Mod | 1996 |
Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcarnitine; Alprostadil; Animals; Diabetic Neuropathies; Dinopros | 1996 |
Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats.
Topics: Acetanilides; Aldehyde Reductase; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weigh | 1996 |
Polyol pathway, 2,3-diphosphoglycerate in erythrocytes and diabetic neuropathy in rats.
Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Body Weight; Diabetic Neuropathies; Diphosphogl | 1995 |
Effects of a novel potent aldose reductase inhibitor, GP-1447, on aldose reductase activity in vitro and on diabetic neuropathy and cataract formation in rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Cataract; Diabetes Mellitus, Experimental; | 1997 |
The level of erythrocyte aldose reductase: a risk factor for diabetic neuropathy?
Topics: Adult; Age Factors; Aged; Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neu | 1997 |
Changes in erythrocyte sorbitol concentrations measured using an improved assay system in patients with diabetic complications and treated with aldose reductase inhibitor.
Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabet | 1998 |
Amelioration of neurovascular deficits in diabetic rats by a novel aldose reductase inhibitor, GP-1447: minor contribution of nitric oxide.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic N | 1998 |
Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relati | 1999 |
A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, C | 1999 |
Sorbitol and myo-inositol levels and morphology of sural nerve in relation to peripheral nerve function and clinical neuropathy in men with diabetic, impaired, and normal glucose tolerance.
Topics: Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glucose Intolerance; Glucose Tolerance Test; Human | 2000 |
Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic N | 2000 |
Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass-spectrometry in type 2 diabetes to assess polyol pathway activity.
Topics: Adult; Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retino | 2001 |
Slowing of motor nerve conduction velocity in streptozotocin-induced diabetic rats is preceded by impaired vasodilation in arterioles that overlie the sciatic nerve.
Topics: Acetylcholine; Animals; Arterioles; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Neuropathi | 2000 |
[Physiopathology of chronic complications in diabetes: therapeutic implications].
Topics: Adult; Aged; Arteriosclerosis; Blood Platelets; Diabetes Complications; Diabetic Angiopathies; Diabe | 1979 |
[Do sorbit and fructose aggravate the diabetic lento- and neuropathy?].
Topics: Age Factors; Blood Glucose; Cataract; Diabetic Neuropathies; Diet, Diabetic; Fructose; Humans; Sorbi | 1978 |
Cerebrospinal fluid sorbitol and myoinositol in diabetic polyneuropathy.
Topics: Adult; Aged; Blood Glucose; Diabetic Neuropathies; Dietary Carbohydrates; Humans; Hypoglycemic Agent | 1977 |
Effect of a prostaglandin I2 derivative (iloprost) on peripheral neuropathy of diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetic Neuropath | 1992 |
A combination of the aldose reductase inhibitor, statil, and the prostaglandin E1 analogue, OP1206.alpha CD, completely improves sciatic motor nerve conduction velocity in streptozocin-induced chronically diabetic rats.
Topics: Aldehyde Reductase; Alprostadil; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hy | 1992 |
Effects of a new aldose reductase inhibitor, (2S, 4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-ca rboxamid e (SNK-860), on the slowing of motor nerve conduction velocity and metabolic abnormalities in the peripheral nerve in acute streptozo
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic N | 1992 |
The role of cyclic adenosine 3',5'-monophosphate and polyol metabolism in diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Diabetes Me | 1992 |
Dissociation between biochemical and functional effects of the aldose reductase inhibitor, ponalrestat, on peripheral nerve in diabetic rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetic Neuropathies; Fructose; Hypoglycem | 1992 |
Effect of niceritrol on streptozocin-induced diabetic neuropathy in rats.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fructos | 1992 |
[Diabetic neuropathy--pathogenesis and precipitating factors].
Topics: Alcohol Drinking; Animals; Diabetic Neuropathies; Energy Metabolism; Fructose; Glucose; Humans; Imid | 1991 |
Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Neuropathies; Diabetic Retinopathy; Female; Kinetics | 1991 |
Studies on WF-3681, a novel aldose reductase inhibitor. IV. Effect of FR-62765, a derivative of WF-3681, on the diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Furans; Kinetics; Male; Motor Neurons; Neural Co | 1991 |
Properties of novel aldose reductase inhibitors, M16209 and M16287, in comparison with known inhibitors, ONO-2235 and sorbinil.
Topics: Aldehyde Reductase; Animals; Benzofurans; Cataract; Cattle; Diabetic Neuropathies; Hydantoins; Imida | 1991 |
[Diabetic complication].
Topics: Aldehyde Reductase; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Diabe | 1991 |
Effects of long-term aldose reductase inhibition on development of experimental diabetic neuropathy. Ultrastructural and morphometric studies of sural nerve in streptozocin-induced diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inositol; Male; | 1990 |
[Alterations in the sorbitol pathway and Na(+)-K(+)-ATPase activity of peripheral nerve of alloxan-induced diabetic rats].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucose; Inositol; Male; Ouabain; R | 1990 |
A new prostaglandin E1 analogue (TFC-612) improves the reduction in motor nerve conduction velocity in spontaneously diabetic GK (Goto-Kakizaki) rats.
Topics: Aging; Alprostadil; Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabeti | 1990 |
Clinical significance of erythrocyte sorbitol-blood glucose ratios in type II diabetes mellitus.
Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; E | 1990 |
A sodium-pump defect in diabetic peripheral nerve corrected by sorbinil administration: relationship to myo-inositol metabolism and nerve conduction slowing.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Energy Metabolism; Humans; Imidazol | 1986 |
Studies of sorbinil on axonal transport in streptozotocin-diabetic rats.
Topics: Animals; Axonal Transport; Blood Glucose; Choline O-Acetyltransferase; Diabetes Mellitus, Experiment | 1986 |
Treatment with an aldose reductase inhibitor can reduce the susceptibility of fast axonal transport following nerve compression in the streptozotocin-diabetic rat.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Diabetes Mellitus, Experimental; Diabetic Neuropathie | 1987 |
Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats.
Topics: Animals; Axonal Transport; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fatty Acids, Esse | 1989 |
Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induced diabetic rats.
Topics: Aldehyde Reductase; Animals; Axons; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactos | 1989 |
The effect of aldose reductase inhibition on the pattern of nerve conduction deficits in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inositol; Kinet | 1989 |
Effect of prostaglandin E1 analogue TFC 612 on diabetic neuropathy in streptozocin-induced diabetic rats. Comparison with aldose reductase inhibitor ONO 2235.
Topics: Adenosine Triphosphate; Aldehyde Reductase; Alprostadil; Animals; Diabetes Mellitus, Experimental; D | 1989 |
[Recent advances in the pathogenesis of diabetic neuropathy].
Topics: Animals; Axons; Diabetic Neuropathies; Humans; Inositol; Phosphocreatine; Sorbitol | 1989 |
[Causes and treatment of diabetic complications].
Topics: Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Glycosylatio | 1989 |
Polyols and myo-inositol in diabetic neuropathy--of mice and men.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactitol; Inositol; Mice; Periphe | 1989 |
The pathogenesis and prevention of diabetic neuropathy and nephropathy.
Topics: Aldehyde Reductase; Diabetic Nephropathies; Diabetic Neuropathies; Glucose; Humans; Phosphatidylinos | 1988 |
Pathogenesis of diabetic neuropathy.
Topics: Diabetic Neuropathies; Humans; Inositol; Peripheral Nerves; Sorbitol | 1989 |
Experimental chronic hypoxic neuropathy: relevance to diabetic neuropathy.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Electrophysiology; Glycated Hemoglobin; Hexo | 1986 |
Axonal transport and nerve conduction velocity in animal models of diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Axons; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Imidazol | 1985 |
Recent advances in the therapy of diabetic peripheral neuropathy by means of an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Biological Transport; Diabetic Neuropathies; Humans; Imidazoles; Imidaz | 1985 |
Effect of aldose reductase inhibitor ONO 2235 on reduced sympathetic nervous system activity and peripheral nerve disorders in STZ-induced diabetic rats.
Topics: Aldehyde Reductase; alpha-Methyltyrosine; Animals; Autonomic Nervous System Diseases; Diabetes Melli | 1987 |
The polyol pathway in dysfunction of diabetic peripheral nerve.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Humans; Inositol; Neural Conduction; Peripheral | 1985 |
Studies of aldose reductase using neuronal cell culture and ligated rat sciatic nerve.
Topics: Aldehyde Reductase; Animals; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic N | 1986 |
Nerve glucose, fructose, sorbitol, myo-inositol, and fiber degeneration and regeneration in diabetic neuropathy.
Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Diabetes Mellitus; Diabetic Neuropathies; Erythrocytes; | 1988 |
A new prostaglandin E1 analogue (TFC-612) prevents a decrease in motor nerve conduction velocity in streptozocin-diabetic rats.
Topics: Alprostadil; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inositol; Insulin; Mal | 1988 |
Peripheral nerve function in relation to quality of metabolic control in diabetes.
Topics: Adolescent; Adult; Aged; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Erythrocytes; Female; Hum | 1987 |
[Effect of trapidil on neuropathy in diabetic mice].
Topics: Animals; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Experimental; Diabetic Neuropathies; In | 1986 |
Effects of a fructose-rich diet and the aldose reductase inhibitor, ONO-2235, on the development of diabetic neuropathy in streptozotocin-treated rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Carbohy | 1985 |
Role of sorbitol pathway in neuropathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Disease Models, Animal; Fructose; | 1973 |
Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor.
Topics: Acetates; Administration, Oral; Alcohol Oxidoreductases; Animals; Cataract; Culture Techniques; Diab | 1973 |
[Pathobiochemistry of the late-onset diabetic syndrome].
Topics: Age Factors; Alcohol Oxidoreductases; Animals; Basement Membrane; Cataract; Diabetes Mellitus; Diabe | 1974 |
The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord.
Topics: Animals; Axons; Blood Glucose; Cauda Equina; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dia | 1968 |
Aetiogenesis of diabetic neuropathy.
Topics: Animals; Demyelinating Diseases; Diabetic Neuropathies; Humans; Nerve Degeneration; Peripheral Nerve | 1972 |
[Pathogenesis of angio- and neuropathies in patients with diabetes mellitus].
Topics: Blood Vessels; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic | 1973 |
[Diabetic neuropathy and the sorbitol cycle].
Topics: Animals; Blood Glucose; Brain; Diabetic Neuropathies; Glucose; Humans; In Vitro Techniques; Nervous | 1969 |
Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fructose; Glucose; In Vitro Techniq | 1966 |
Free sugars in alloxan diabetic rat nerve.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fructose; Glucose; In Vitro Techniq | 1966 |