sorbitol has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernard, E | 1 |
| Pegat, A | 1 |
| Vallet, AE | 1 |
| Leblanc, P | 1 |
| Lumbroso, S | 1 |
| Mouzat, K | 1 |
| Latour, P | 1 |
| Hans, F | 1 |
| Glasebach, H | 1 |
| Kahle, PJ | 1 |
| Dewey, CM | 1 |
| Cenik, B | 1 |
| Sephton, CF | 1 |
| Dries, DR | 1 |
| Mayer, P | 1 |
| Good, SK | 1 |
| Johnson, BA | 1 |
| Herz, J | 1 |
| Yu, G | 1 |
| Heiss, WD | 1 |
| Prosenz, P | 1 |
| Herles, HJ | 1 |
4 other studies available for sorbitol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Juvenile amyotrophic lateral sclerosis associated with biallelic c.757delG mutation of sorbitol dehydrogenase gene.
Topics: Amyotrophic Lateral Sclerosis; Charcot-Marie-Tooth Disease; Humans; L-Iditol 2-Dehydrogenase; Mutati | 2022 |
Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules.
Topics: Acetylcysteine; Adenine; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Frontotemporal Dementi | 2020 |
TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.
Topics: Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Animals; Biological Assay; Cell Line; Cells, Cul | 2011 |
[Effect of hemodilution and dehydration on regional cerebral circulation].
Topics: Amyotrophic Lateral Sclerosis; Brain; Brain Damage, Chronic; Brain Neoplasms; Cerebrovascular Circul | 1973 |