sorbitol has been researched along with Alzheimer Disease in 2 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A characteristic hallmark of Alzheimer's disease brain is the presence of hyperphosphorylated tau; however, the mechanisms responsible for the aberrant tau phosphorylation are unknown." | 1.31 | Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells. ( Johnson, GV; Stoothoff, WH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, J | 1 |
| Begley, P | 1 |
| Church, SJ | 1 |
| Patassini, S | 1 |
| McHarg, S | 1 |
| Kureishy, N | 1 |
| Hollywood, KA | 1 |
| Waldvogel, HJ | 1 |
| Liu, H | 1 |
| Zhang, S | 1 |
| Lin, W | 1 |
| Herholz, K | 1 |
| Turner, C | 1 |
| Synek, BJ | 1 |
| Curtis, MA | 1 |
| Rivers-Auty, J | 1 |
| Lawrence, CB | 1 |
| Kellett, KA | 1 |
| Hooper, NM | 1 |
| Vardy, ER | 1 |
| Wu, D | 1 |
| Unwin, RD | 1 |
| Faull, RL | 1 |
| Dowsey, AW | 1 |
| Cooper, GJ | 1 |
| Stoothoff, WH | 1 |
| Johnson, GV | 1 |
2 other studies available for sorbitol and Alzheimer Disease
| Article | Year |
|---|---|
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.
Topics: Aged; Alzheimer Disease; Animals; Blood Glucose; Brain; Case-Control Studies; Copper; Dementia; Fema | 2016 |
Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells.
Topics: Alzheimer Disease; Apoptosis; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cysteine Proteina | 2001 |